News Archive

13/11/2025 | The University of Cologne is once again represented in the international ranking of ‘Highly Cited Researchers’, which is published annually by Clarivate Analytics based on information from the ‘Web of Science’ publication database.

11/11/2025 | First biomarkers for rapid diagnosis and targeted therapy / Tuberculosis (TB) is one of the world's leading infectious diseases. Infection with the bacterium "Mycobacterium tuberculosis" primarily affects the lungs, but in up to 25 percent of all infected individuals, it also affects other parts of the body, such as the lymph nodes, bones, or brain.

06/11/2025 | In a joint project, the two University of Cologne scientists are investigating mutations of viral pathogens in connection with the immune response. The European Research Council awards ERC Synergy Grants to interdisciplinary groups of two to four excellent researchers.

05/11/2025 | Over half a million euros in funding from the German Research Foundation (DFG) goes to Prof. Dr. Miguel Alejandre Alcazar (Translational Experimental Pediatrics, Department of Pediatrics, associated to the CMMC, University Hospital Cologne Institute for Lung Health, Justus Liebig University Giessen) and Dr. Julian Wagner (Institute of Cardiovascular Regeneration, Goethe University Frankfurt)

04/11/2025 | Antibodies against virulence factors of "Pseudomonas aeruginosa" could become an alternative to antibiotics in the future. A team from Cologne University Hospital has been awarded the 2025 "Galenus von Pergamon Prize" for basic research for its work in this field.

03/11/2025 | Researchers from the University of Cologne discovered how a specific dietary amino acid increases cellular energy, opening new possibilities for treating metabolic diseases

31/10/2025 | A research team from the UKK and the CMMC has developed and systematically compared macrophage co-culture systems in chronic lymphocytic leukemia (CLL). The study provides the first comprehensive analysis of these models and proposes a new experimental standard for reproducible investigations into leukemia-microenvironment interactions.

21/10/2025 | A research team at the University of Cologne and University Hospital Cologne identifies a circuit in the brain that counteracts anxiety and helps to restore balanced behaviour. The result could contribute to developing treatment options for anorexia nervosa, one of the deadliest mental illnesses.

17/10/2025 | This year's Prize for European HIV Research (ANRS MIE Award for the Best Basic/Translational Paper on HIV) goes to Prof. Dr. Dr. Philipp Schommers, Clinic I for Internal Medicine at Cologne University Hospital and associated to the Center of Molecular Medicine Cologne (CMMC).

14/10/2025 | A new study shows that disease-causing changes in the MFN2 gene in Charcot-Marie-Tooth syndrome trigger programmed cell death – a potential key to understanding the incurable nerve disease / publication in “Journal of Cell Science”

09/10/2025 | Additional €1.55 million from the Else Kröner-Fresenius-Stiftung - Antibiotic resistance is one of the greatest medical challenges of our time. Infections with multi-resistant pathogens are increasingly leading to severe disease progression, long hospital stays, and rising mortality rates.

07/10/2025 | A new study by the Laboratory for Experimental Immunology of the Eye at Cologne University Hospital and the Faculty of Medicine reveals new, promising methods for preventing eye damage in diabetic retinopathy (DR) by targeting the immune response within the retina.

07/10/2025 | A Cologne-led research team has discovered the antibody 04_A06, which neutralizes the human immunodeficiency virus (HIV) in almost all tested variants in vitro and even overcomes typical resistance mechanisms. The discovery potentially opens up new perspectives for the prevention and treatment of HIV infections.

06/10/2025 | University Professor Florian Klein, Director of the Institute of Virology at Cologne University Hospital, Executive Board Member at the Center for Molecular Medicine Cologne (CMMC) and a leading international expert in human immunodeficiency virus (HIV), has been awarded the 2025 Hamburg Science Prize for his work on immunomodulation.

02/10/2025 | In response to cellular stress, the protein CxUb is activated to identify damaged proteins, thereby maintaining cellular health. The discovery could lead to ways to improve the treatment of cancer and neurodegenerative diseases

22/09/2025 | Scientists in Cologne offer a molecular perspective on the architecture of a synapse. They have discovered that a protein in the brain forms flexible filaments, thereby acting as an essential building block of inhibitory synapses.

18/09/2025 | A molecular protective mechanism keeps fat cells healthy, protects against metabolic diseases and plays an important role during the ageing process / These findings could contribute to better early detection and treatment in the future / Publication in ‘Science Advances’

15/09/2025 | An international team of scientists have discovered that microbes associated with tumours produce a molecule, which can control cancer progression and boost the effectiveness of chemotherapy / publication in "Cell Systems".

11/09/2025 | A research team at the University of Cologne and the Max Delbrück Center in Berlin has deciphered in detail the rules behind an important mechanism of cellular quality control in humans / Publication in ‘Molecular Cell’

11/09/2025 | Researchers reveal that lung cancer cells form direct synapses with neurons to grow and proliferate, opening the door to new therapies that cut the communication lines / publication in ”Nature”

09/09/2025 | On September 8, the University Election Assembly — consisting of an equal number of members of the Senate and members of the University of Cologne’s University Council — elected Professor Dr Carien Niessen as Vice-Rector for Research.

05/09/2025 | At the Heart Center of Cologne University Hospital, the team of doctors led by Prof. Stephan Baldus, Director of Department III for Internal Medicine, Matti Adam, and Dennis Mehrkens has successfully implanted a Sapien M3 mitral valve prosthesis for the first time in North Rhine-Westphalia.

03/09/2025 | A University of Cologne research team has identified a direct molecular link between aging and neurodegeneration by investigating how age-related changes in cell signalling contribute to toxic protein aggregation

21/08/2025 | A preclinical study at the University of Cologne could open up new treatment options for STING-associated vasculopathy with onset in infancy (SAVI) and benefit a wide spectrum of other currently therapy-resistant genetic diseases

18/08/2025 | The Skin Cancer Prevention Project DIE SONNE UND WIR is running the "UV-Schutz im Freibad – Mach den Sonnencheck" campaign to raise awareness of UV protection, in collaboration with KölnBäder.

06/08/2025 | Dr. Sebastian Theobald and Louise M. Cremer take on key board roles at the Young Immunologists of the German Society for Immunology (DGfI).

04/08/2025 | Together with the CMMC´s outreach project “DIE SONNE UND WIR” the Cologne University Hospital is participating in the campaign “UV-Schutz im Freibad - Mach den Sonnencheck” to raise awareness about sun protection and skin cancer prevention.

04/08/2025 | A University of Cologne research team has discovered that cells in high-energy-demanding tissues respond to mitochondrial dysfunction in a surprising way.

01/08/2025 | Prof. Dr. Brunhilde Wirth, director of the Institute of Human Genetics at Cologne University Hospital and Executive Board Member at the Center for Molecular Medicine Cologne (CMMC), appeared as an expert guest on the WDR5 podcast series “Neugier genügt” to discuss human genetics and rare diseases.

31/07/2025 | We congratulate Kasia Bozek, member at the CMMC, on the wonderful portrait about her and her work in the magazine “make ideas work” (Publisher: Gateway Exzellenz Start-up-Center, University of Cologne, Author: Manuel Heckel, Photos: Natalie Bothur).

28/07/2025 | A research team at the University of Cologne has developed a method called DynaTag, which can detect the binding of proteins to DNA, even in an individual cell. Interactions of proteins with DNA are crucial for gene expression, which has a major impact on diseases such as cancer / publication in ‘Nature Communications’

21/07/2025 | A University of Cologne research team has developed a novel approach to predict how fast kidney disease is likely to progress, using just blood samples. They discovered 29 proteins that are linked to how quickly kidney function declines each year / Publication in Nature Communications

04/07/2025 | Together with Professor Dr. Andreas Speer and Professor Dr. Christiane Josephine Bruns, three Cologne professors will be members of the Senate of the German Research Foundation from January 1, 2026 / Thomas Benzing is responsible for Clinical Medicine I.

01/07/2025 | The European Molecular Biology Organisation (EMBO) has elected Anne Schaefer, Director at the Max Planck Institute for the Biology of Ageing and researcher at the Center for Molecular Medicine Cologne (CMMC), as a new member.

27/06/2025 | A University of Cologne research team has identified the protein AIFM1 as a central coordinator of cellular energy production.

24/06/2025 | We are deeply saddened to announce the passing of Prof. Dr. Dr. Dres. h.c. Wilhelm Stoffel, who died on June 24, 2025, at the age of 97.

18/06/2025 | With the launch of the EVH, a new European project for pandemic preparedness vaccine development is taking off.

16/06/2025 | Hope for more effective treatment for aggressive B-cell lymphoma: A research team from the University Hospital of Cologne and the Faculty of Medicine at the University of Cologne has discovered a previously unknown mechanism ...

13/06/2025 | At its 37th annual meeting in Nuremberg, the German Society for Ophthalmic Surgery (DOC) presented the DOC Research Award to Prof. Dr. Claus Cursiefen, Director of the Center for Ophthalmology at the University Hospital of Cologne ...

11/06/2025 | The "Green-up Your Lab competition" is now open to all research teams at the University of Cologne and University Hospital Cologne! Do you have a creative idea to make your lab more sustainable - by reducing waste, saving energy, or rethinking how resources are used? Click here ...

05/06/2025 | The research group led by Professor Dr. Johannes Vogt (Institute of Anatomy II, Molecular and Translational Neuroscience Group of the Medical Faculty of the University of Cologne and principle investigator at the Center for Molecular Medicine Cologne) and the researchers involved were recently awarded the Best Publication Award 2024 of the Anatomical Society ...

04/06/2025 | Professor Dr. Axel Heidenreich, director of urology at the University Hospital of Cologne and associated member of the Center for Molecular Medicine Cologne (CMMC) , was appointed chairman and spokesman of the guideline commission on testicular germ cell tumors by the European Society of Urology.

04/06/2025 | Professor Dr. Florian Klein, director of the Institute of Virology at Cologne University Hospital and Executive Board Member at the Center for Molecular Medicine Cologne (CMMC), was appointed a new member of the Leopoldina - the National Academy of Sciences.

03/06/2025 | of Professor Kurt Pfannkuche at the Faculty of Medicine (University of Cologne). The ZukunftBio.NRW funding of €850,000 marks an important step towards advancing potential regenerative therapies for myocardial infarction.

30/05/2025 | The German Research Foundation (DFG) has approved a new Transregional Collaborative Research Centre at the University of Cologne: Together with scientists at the Universities of Hamburg and Münster, the researchers will study the control processes in the kidney filter.

28/05/2025 | Researchers at the Max Planck Institute for Biology of Ageing (one of them Professor Andreas Beyer, Principle Investigator at the Center for Molecular Medicine Cologne) have discovered that the combination of the two cancer drugs Rapamycin and Trametinib significantly extends the lifespan of mice.

28/05/2025 | Obesity is a global health problem that affects many people. In recent years, very promising anti-obesity drugs have been developed. Despite these successes, there are patients who do not respond to these drugs or suffer from side effects. Therefore, there is still an unmet need for therapies. Researchers at the Max Planck Institute for Metabolism Research

27/05/2025 | CECAD researcher, clinical mycology expert and associated principle investigator at the Center for Molecular Medicine Cologne (CMMC) Professor Dr. Oliver A. Cornely will serve as President of ISHAM, the leading global society for fungal infections.

23/05/2025 | Five proposals for Clusters of Excellence win funding in the federal competition / Clusters in the fields of aging research, astrophysics, plant sciences, quantum research and economics will receive funding

20/05/2025 | The Center for Molecular Medicine Cologne (CMMC) congratulates Professor Aleksandra Trifunovic on receiving the University of Cologne’s Max Delbrück Prize for her pioneering contributions to mitochondrial biology.

19/05/2025 | The West German Genome Center has been re-established on a new legal basis, allowing it to continue its internationally competitive genome research in the medical field and the life sciences.

12/05/2025 | You are invited to the Annual Meeting 2025 of the International Genetic Epidemiology Society (IGES), the premier gathering for experts in genetic epidemiology and statistical genetics!

02/05/2025 | The Center for Molecular Medicine Cologne (CMMC) congratulates Professor Jens Brüning on receiving the University Award for Research 2024 in recognition of his exceptional scientific achievements and his contribution to Cologne’s reputation as a leading research hub.

02/05/2025 | As part of the European Union's (EU) MSCA funding line, the STEM-CORE project, which includes the Center for Ophthalmology at the University Hospital of Cologne, will receive more than four million euros.

28/04/2025 | Interdisciplinary Progam Molecular Medicine - From May 19 - 20, 2025

25/04/2025 | A research team has discovered that the enzyme myeloperoxidase (MPO) plays an important role in vascular health in obese people

23/04/2025 | Professor Dr. Dr. Jan Rybniker, Cologne, and Professor Dr. Rolf Müller, Saarbrücken, are starting a collaboration with the Institut Pasteur in Paris.

23/04/2025 | New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal ageing

14/04/2025 | The DFG is providing €500,000 for three-years for his research, which is closely tied to the CRC 1607.

09/04/2025 | How can data-driven medicine help fight breast cancer better? Host Vivian Polenz visited researchers at the University of Cologne for the Mindblown University YouTube channel. The video was produced on behalf of the BMBF.

08/04/2025 | for his outstanding scientific achievements in neuroblastoma research

07/04/2025 | Damage to the mitochondria, the “power plants” of the cells, contributes to many diseases.

04/04/2025 | A new DFG-funded research group investigates how proteostasis is regulated at the organismal level and its impact on aging and disease.

04/04/2025 | Early administration of the drug Fosdenopterin/rcPMP improves the chances of survival of infants with MoCD type A and promotes the development of brain functions

24/03/2025 | Researchers at the University of Cologne have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system.

21/03/2025 | Funded by the German Center for Infection Research - The rise of antibiotic resistance is a global health problem associated with increasing mortality and significantly higher healthcare costs.

28/02/2025 | Researchers at the University of Cologne have identified a specific form of the tau protein that is responsible for mediating the toxicity of harmful protein clumps in human neurons

18/02/2025 | Dept. of General, Visceral, Thoracic and Transplant Surgery at Cologne University Hospital and the Medical Faculty of the University of Cologne

13/02/2025 | A European research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating Charcot-Marie-Tooth disease / publication in ‘Nature Communications’

07/02/2025 | Advancing global collaboration to accelerate breakthroughs in healthy aging.

07/02/2025 | A high-resolution spatial map of the human hypothalamus makes it possible to identify specific cells, determine their exact location and analyse their neighbouring cells.

16/01/2025 | Scientists have discovered a novel autophagy mechanism that protects the brain cells of mice and opens up new therapeutic approaches for the treatment of neurogenerative diseases.

03/01/2025 | The Donation goes to the Dept. of Exp. Pediatric Oncology at the University Hospital Cologne headed by Professor Matthias Fischer

20/12/2024 | honored for his pioneering contributions to optimizing minimally invasive corneal transplantation.

17/12/2024 | to Investigate Metabolic Implications of Neuron-Tumor Interactions

16/12/2024 | In recognition of her work in identifying microglial immune mechanisms and targets to optimize AAV-based gene therapies for retinal degeneration.

06/12/2024 | Cologne Scientist Prof. Axel Heidenreich receives €700.000 funding for his research on yolk sac tumors

29/11/2024 | Two of the three silver medals awarded this year by the Walter Siegenthaler Society go to Prof. Dr. Dr. Philipp Schommers and Dr. Alexander Simonis, both from the Clinic I for Internal Medicine at the University Hospital Cologne and the Medical Faculty of the University of Cologne.

27/11/2024 | STOP-PKD is the first study to evaluate the safety and efficacy of SGLT2 inhibitors in patients with ADPKD.

26/11/2024 | Two Collaborative Research Centres involving the University of Cologne will receive funding from the German Research Foundation (DFG) for a further funding period. One of them is the CRC 1451.

22/11/2024 | The University of Cologne is once again represented in the international ranking ‘Highly Cited Researchers’, which is published annually by Clarivate Analytics based on information from the publication database ‘Web of Science’.

21/11/2024 | He received the award for his research on how olfactory receptor 2 drives abdominal aortic aneurysm by promoting CX3CR1-mediated monocyte recruitment at the German Cardiac Societies’ Heart Conference in Sept. 2024.

19/11/2024 | Research Training Groups receive over 9.5 million Euros in funding from the DFG

15/11/2024 | At its 122nd Annual Meeting in Berlin, the German Ophthalmological Society (DOG) elected Prof. Dr. Claus Cursiefen, Director of the Center for Ophthalmology at the University Hospital of Cologne, as Secretary General for a further four years.

04/11/2024 | Experts from the University of Cologne highlight the importance of tumor-associated macrophages (TAMs) and their multifaceted role during disease pathogenesis.

28/10/2024 | The CMMC hosted an event on student mobility between German and Italian universities. The event was a joint initiative of the Italian Consulate General in Cologne, the Forum Accademico Italiano (FAI), the Orizzonti platform of Com.It.Es. in Cologne and the University of Cologne.

17/10/2024 | Professor Dr. Stephan Baldus has been elected President of the Ordinarienkonferenz Kardiologie e.V. for the next two years.

15/10/2024 | Honor for special services to medicine: Prof. Dr. Michael Hallek has been awarded the Order of Merit of the Federal Republic of Germany in Cologne´s historic town hall.

01/10/2024 | Researchers from the University of Cologne and University Hospital Cologne have discovered key factors that determine different disease progressions in rare lung tumors / publication in the ‘Journal of Clinical Oncology’

27/09/2024 | This interdisciplinary research facility, operated jointly by the Faculty of Medicine and the Faculty of Mathematics and Natural Science, is dedicated to investigating the pathological mechanisms underlying diseases and the development of novel therapeutic strategies.

06/09/2024 | The Center for Ophthalmology at the University Hospital of Cologne has once again maintained its leading position in the field of corneal transplants in Germany in 2023.

04/09/2024 | Scientists at the University of Cologne, in collaboration with international partners, have developed a new experimental setup to induce sustained muscle contraction in nematodes using blue light alone.

03/09/2024 | Scientists at the University of Cologne have discovered that coordination between basic cellular processes is lost with increasing age / publication in ‘Nature Aging’

26/08/2024 | University of Cologne scientists have found that the protein histone H1.2 and the enzyme PARP1 could be potential therapeutic targets to decrease neurodegeneration in amyotrophic lateral sclerosis (ALS) / publication in ‘Cell Reports’

26/08/2024 | University of Cologne - New AI-based digital platform enables extremely fast and accurate analysis of tissue sections from lung cancer patients / publication in ‘Cell Reports Medicine’

20/08/2024 | Prof. Dr. Gereon R. Fink is honored as one of the most cited German neuroscientists for outstanding scientific achievements in the neurosciences.

31/07/2024 | The results of the new study could have significant implications for advancing our understanding of diabetes / publication in ‘Molecular Metabolism’

17/07/2024 | The Medical Faculty of the University of Cologne offers positions in the Cologne Clinician Scientist Program (CCSP), a training program for Clinician Scientists with a strong focus on translational and / or clinical research.

12/07/2024 | The General Assembly of the German Research Foundation (DFG) re-elected Prof. Dr. Christiane J. Bruns from the University Hospital of Cologne and the Faculty of Medicine of the University of Cologne for a second term of three years (2025-2027) at the DFG Annual Meeting in Potsdam.

09/07/2024 | Together with other internationally renowned European scientists, the European Molecular Biology Organization (EMBO) has accepted the molecular biologist Professor Dr Aleksandra Trifunovic from the Institute of Mitochondrial Diseases and Ageing at the University of Cologne’s Faculty of Medicine, the CMMC Center for Molecular Medicine Cologne and the CECAD Cluster of Excellence for Aging Research as a new member.

10/06/2024 | The German Research Foundation (DFG) has approved a new Collaborative Research Center in mRNA research and extended funding for the CRC 1218 on mitochondria

07/06/2024 | A genetic disorder leads to an increase in bioactive lipids in the brain promoting mental disorders. New study shows that treatment with an enzyme inhibitor that prevents the activation of lipids can restore balance and alleviate symptoms.

29/05/2024 | The University of Cologne is holding events to promote equal opportunities - organized by the Vice Rectorate for Anti-Discrimination, Equal Opportunities and the Equal Opportunities Unit and cooporating partners.

17/05/2024 | The study highlights the importance of the integration of spatial and genetic data for the prediction of at-risk populations and the guidance of future research and policy. Publication in "Environ Health Perspect"

06/05/2024 | Two scientists from the University of Cologne have discovered that aging clocks are based on random events / publication in ‘Nature Aging’

26/04/2024 | The brain sends signals to the liver earlier than previously assumed, which then adapts the sugar metabolism - publication in ‘Science’.

11/04/2024 | Metabolism researcher Jens Brüning and geneticist Thorsten Hoppe, both working group leaders at the Cluster of Excellence for Aging Research CECAD and the Center for Molecular Medicine Cologne, receive European Research Council awards.

10/04/2024 | An international research team, led by PD Dr. Hajar Maleki (University of Cologne), has developed a novel approach to bone tissue engineering, that has the potential to significantly advance the restoration of damaged bone tissues in post-surgery osteosarcoma treatment.

08/04/2024 | New finding from scientists at the University of Cologne’s CECAD and CMMC discloses how mitochondria control tissue rejuvenation and synaptic plasticity in the adult mouse brain / publication in ‘Neuron’

08/04/2024 | After a 9-month certification process, four research groups at laboratory level 1 of the Center for Molecular Medicine Cologne (CMMC research building) have received the sustainability certificate awarded by the non-profit organization My Green Lab - with the highest certification level "Green". In the initial assessment, the CMMC research groups led by Dr. Hänsel-Hertsch, Dr. Simon Pöpsel, Dr. Debora Trentini and PD Dr. Catherin Niemann had already achieved bronze status.

18/03/2024 | Project involving the University of Cologne gives insights into a key brain function / publication in ‘Nature Neuroscience’

08/03/2024 | For the first time, scientists from the University of Cologne (UoC) have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory. They could be used as artificial nucleic acids for therapeutic applications / publication in ‘Journal of the American Chemical Society’

07/03/2024 | Researchers from the University of Cologne (UoC) have discovered a regulatory mechanism that prevents an excessive and harmful immune response / publication in ‘Nature Communications’

16/02/2024 | Scientists at University Hospital Cologne have developed a procedure in the laboratory that effectively fights affected cells in lymphoma cancer without harming healthy immune cells, a common issue with comparable therapies / publication in ‘Cell Reports Medicine’

06/02/2024 | three scientists from Cologne - in recognition of their outstanding contributions to lung cancer diagnostics and therapy, specifically within the framework of the "National Network Genomic Medicine (nNGM) Lung Cancer", which they initiated.

01/02/2024 | DNA and RNA research is revolutionizing pharmaceutics: New drugs are being developed faster and at a lower cost, and they are effective against previously incurable diseases.

02/01/2024 | An international research team led by Jan Rybniker has identified several substances that have a dual effect against tuberculosis. These substances reduce the pathogenicity of the bacteria responsible for the disease in human immune cells and boost the activity of conventional antibiotics. The findings were published in 'Cell Chemical Biology'.

08/12/2023 | Cologne scientists decipher how the antibody response of our immune system reacts to a coronavirus infection and prepares for future infections / Publications in ‘Immunity’ and ‘Science Immunology’

06/12/2023 | With the € 1.1 Mio. Professorship Funding from Else Körner Foundation, Philipp Schommer is dedicated to further advance antiviral therapies and vaccines. Further information: Schommers Laboratory of Antiviral Immunity

29/11/2023 | The German research Foundation (DFG) has approved a Collaborative Research Centre (CRC) in the field of ophthalmology / CRCs on cell death and Arctic climate research are being further funded.

02/11/2023 | Broadly neutralizing antibodies are already being used to fight viruses. This approach could also help to treat infections with multi-resistant bacteria in the future / publication in the renowned journal ‘Cell’

26/10/2023 | The ERC BATPROJECT "Learning from Bats: New strategies to extend healthspan and improve diseases resistancce". European Research Council (ERC) is funding the project ‘BATPROTECT’ with 11.9 million euros over a period of six years

04/10/2023 | In planta expression of human polyQ-expanded huntingtin fragment reveals mechanisms to prevent disease-related protein aggregation/ new research reported in “Nature Aging” may have found a way to “copy” the mechanism for application in human cells

21/09/2023 | addressed these challenges and successfully contributed to intensify the interdisciplinary exchange. We were delighted to welcome over 320 participants.

27/07/2023 | University of Cologne Scientists discover that cleavage of the protein cFLIP is crucial to limit cell death and promote tissue regeneration / Publication in Science Advances

28/06/2023 | In this study, Cologne researchers demonstrate a differential expression of BTLA on renal immune cells during glomerulonephritis. indicating that the immune checkpoint molecule BTLA has great potential to restrain T-cell mediated kidney inflammation.

02/06/2023 | With deep sadness, we received the news of the loss of our dear friend and colleague Konstantin Belostotski.

26/05/2023 | Cologne researchers identify a novel chaperonopathy causing altered protein O-glycosylation. This discovery will promote a better understanding of the role of complex O-glycans in human health and disease.

22/05/2023 | With this extension, the members of the TRR 259 are excited to continue cutting-edge research into aortic diseases in Cologne, Düsseldorf, and Bonn.

22/05/2023 | Unmet medical needs, societal implications and future therapeutic perspectives.

08/05/2023 | To celebrate the start of the second funding period the FOR 2722 is hosting an International Symposium.

13/04/2023 | In a large joint study, researchers of the University of Cologne, the Cologne Max Planck Institute for Biology of Aging (MPI) and the University of Göttingen have shown that across the animal kingdom with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers and that with dietary restrictions, these processes could be reversed.

30/03/2023 | Researchers of the University of Cologne describe that the competence for the future cardiac fate of human embryonic stem cells (hESCs) is preset in pluripotency by a specialized mRNA translation circuit controlled by RBPMS l published in Science Advances

26/03/2023 | demonstrating that the DREAM complex functions as conserved master regulator of somatic DNA-repair capacities.

25/03/2023 | On March 23, 2023 she receives the national prize the "Duchenne-Erb Prize" in recognition of her life's work as a human geneticist and her outstanding scientific achievements: the elucidation of the genetic cause of spinal muscular atrophy (SMA), the discovery of genetic factors that protect against SMA and the associated cellular pathomechanisms.

23/03/2023 | The 14. Annual Congress of the Technology and Methods Platform for Networked Medical Research (TMF) will focus on the opportunities, risks and challenges of genomic medicine.

16/03/2023 | This year, the CMMC organized the workshop "The secret of the smallest building blocks of your body" and the lecture "Sun - Skin - Shadow" which were parts of the program at the Cologne Children´s University 2023.

06/03/2023 | With over 200 participants the CMMC Annual Retreat (March 02-03, 2023) was a great success. Thanks to the outstanding engagement of CMMC Junior Faculty the participants were offered a high quality scientific program.

01/03/2023 | The topic of the 2023 meeting (March 07-13, 2023) covers the interface between the two Cologne DFG-funded CRCs 1218 and 1403.

28/02/2023 | Plastin 3 escapes X inactivation in some women: on the one hand this protects against spinal muscular atrophy, on the other hand it is a biomarker for cancer

23/02/2023 | Stimulation by the hormone leptin causes hunger to be briefly suppressed in mice when the opportunity for social interaction with the opposite sex and reproduction opens up. However, if hunger is too strong, food intake is preferred / Publication in "Cell Metabolism".

10/02/2023 | On Feb. 9, 2023 the first Sustainability Forum took place and was attended by over 250 members of the University of Cologne or University Hospital of Cologne. This Forum offered an outstanding networking platform to exchange ideas, information and to initiate plans for sustainable transformation.

06/02/2023 | Dr. Débora Trentini Schmidt received the €10,000 Research Award of the Peter and Traudl Engelhorn Foundation in January 9, 2023.

01/02/2023 | A newly created professorship at the Medical Facultyof the University of Cologne. Dr. Leo Kurian has started his W1 professorship on Feb. 1, 2023.

19/01/2023 | Dynamical patterns of electrical potential relate to growth and viability in spatially structured bacterial colonies / publication in PLOS Biology

22/12/2022 | Damage to the paternal genome of the nematode Caenorhabditis elegans cannot be repaired and is instead passed on to its offspring, while the female egg repairs or limits the damage / publication in ‘Nature’.

22/12/2022 | The European Union has supported a research proposal for new therapies to restore visual acuity in rare and severe ocular surface diseases under the Horizon Health Program. The project leader on the Cologne side is Prof. Dr. Claus Cursiefen, Director of the Center for Ophthalmology at the University Hospital of Cologne and the Faculty of Medicine.

09/12/2022 | Scientists from Cologne and Münster investigate how DNA damage triggers the development of age-related diseases / Results could help to prevent age-related diseases.

08/12/2022 | for their study on the evolution of complex genomic amplifications in cancer. They identified a type of amplification named as “seismic amplification”.

28/11/2022 | This research funding award supports the translational project "Disease monitoring by liquid biopsies in genetically complex soft tissue sarcomas" in the field of tumor research with a total of 16,000 euros.

16/11/2022 | Scientists at the University of Cologne have discovered how cells can eliminate mutated mitochondrial DNA (mtDNA).This discovery could open up new therapeutic options to treat aging-associated diseases like Parkinson’s. / publication in ‘Nature Communications’

16/11/2022 | Annual ranking of ‘Highly Cited Researchers’ by the Web of Science Group published as an indicator of outstanding research. University of Cologne represented by five medical researchers, by one physicist, two biologists,

07/11/2022 | A first clinical trial has shown that a ketogenic metabolism can have a positive effect on patients with cystic kidneys / Scientists from the University of Cologne have presented their results at the Kidney Week of the American Society of Nephrology.

24/10/2022 | The University of Cologne is deeply shocked by Russia's attack on Ukraine. We are equally highly concerned for the lives of the people in Ukraine. Peace, democracy and the freedom of research and teaching form the basis of our academic activities.

19/10/2022 | The multicenter and prospective study of the German Center for Infection Research (DZIF) led by the Cologne scientists, funded with almost 680,000 euro, will now help to improve the early detection and treatment of affected patients.

11/10/2022 | Proteins in the gut of the nematode C. elegans are not degraded when its temperature sensors are disturbed. At the same time, the worm's lifespan is extended.

11/10/2022 | Dr. Sebastian Theobald receives dissertation prize of the Paul Ehrlich Society for Infection Therapy.

07/10/2022 | Ground-breaking discoveries in cilia biology have revolutionized our understanding of the critical role of cilia in cell signalling, development, tissue homeostasis and disease.

14/09/2022 | An international scientific research collaboration led by Prof. Brunhilde Wirth (Univ. of Cologne and Univ. Hospital Cologne) and by Prof. Alfredo Brusco (University of Turin, Italy) uncovered how different mutations in CAPRIN1 associate with distinct disorders: one causing alterations in the neural development and one causing neurodegeneration.

31/08/2022 | What constitutes excellent research, what does excellence actually mean, and what is the relationship between excellence and equal opportunities? These and other questions will be addressed at this year's Scientific Career Day.

01/08/2022 | Prof. Dr. Katarzyna Bozek, previously Junior Research Group Leader at the Center for Molecular Medicine Cologne, has received a W2 professorship for Data Analytics in Bioinformatics at the Faculty of Medicine as of August 01, 2022. The W2 professorship with tenure track is located at the Institute of Biomedical Informatics led by of Univ. Prof. Dr. Oya Beyan.

30/07/2022 | to prepare the new CMMC Funding Period (01/2022-12/2025). The evaluation procedure has been initiated

22/07/2022 | A team of scientists led by Roman-Ulrich Müller identified the molecular mechanism underlying caloric restriction and showed that a reduction in the metabolic product 20-hydroxyeicosatetraenoic acid (20-HETE) mediates its protective effect - new perspectives for potential targeted interventions / Publication in "Kidney International".

04/07/2022 | In a new study performed with vaccinated individuals, a research team led by Jan Rybniker at the University of Cologne / the Unviersity Hospital Cologne focus for the first time on the signaling pathways of these immune cells and their effect on the acquired immune response.

29/06/2022 | A group of Cologne scientists and their cooperating partners demonstrated that the brain controls our body’s lysophospholipids, which in turn control a programme that activates nutritional intake / specific inhibitors of lipid synthesis could serve as new obesity therapies / publication in ‘Nature Metabolism’.

08/06/2022 | Frailty has been accepted as the core of geriatric medicine - going far beyond multimorbidity and chronological age - and incorporates aging processes essential to its development and reversibility.

02/06/2022 | organized by and for young researchers - Nov. 16-18, 2022 in Seville (ES). Register now & apply for travel grants!

25/05/2022 | and provides 1.8 million euros for his research on application-oriented infection.

24/05/2022 | The Industrie-Club Düsseldorf in cooperation with the North Rhine-Westphalian Academy of Sciences and Arts honor their outstanding research on the human immune response to viral infectious agents.

17/05/2022 | Two similar proteins can stand in for each other in the quality control mechanism of defective mRNA. This has redefined the distribution of protein tasks / publication in ‘The EMBO Journal’.

23/04/2022 | His research on "Characterization of HIV-1 antibody resistance in patients and its influence on viral fitness" will be funded with a total of approximately 2.3 million euros over the next six years.

22/03/2022 | Scientists at the University of Cologne have shown in an animal model that certain diets protect the kidneys from damage, promising successful clinical application / publication in ‘Translational Research’

21/03/2022 | The CMMC is looking forward to receiving applications from highly talented mid-career scientists, who are members at the University of Cologne and whose scientific profiles meet the CAP requirements.

17/03/2022 | Prestigious EU research prize will support Leo Kurian´s fundamental genetic research into the development of the human heart.

17/03/2022 | To kick-off this year’s membership drive we have arranged for a fabulous online event: 24 hours of nonstop regenerative biology talks spanning the globe!

09/03/2022 | Scientists at the University of Cologne have shown that the recycling program of cells, autophagy, leads to the fusion of several single cells into multinucleated cell units during wound healing / publication in ‘The EMBO Journal’

15/02/2022 | The University of Cologne invites applications to its DFG-funded CCRC Research Training Group 2407 „Inflammatory & Cellular Stress Signaling: Switches to Vascular Dysfunction" - Application Deadline: January 30, 2021

03/01/2022 | The newly established professorship is linked to the establishment of a dedicated Institute at the Faculty of Medicine, University of Cologne.

22/12/2021 | Identification of a novel population of “ultrashort” cell-free DNA with G-quadruplex potential reduced abundance and G4-forming potential in blood plasma of healthy individuals than of patients with cancer.

18/12/2021 | The study provides data that could improve treatment of a subset of EGFR-mutated lung tumors that no longer respond to standard therapy.

26/11/2021 | The award of the new CRC 1530 (speaker - Michael Hallek) and the extension of the CRC 1310 (speaker - Michael Lässig) refers to the great team of scientists at the University of Cologne and their cooperating partners. Scientists from the CMMC are involved in both CRCs.

17/11/2021 | The study provides novel insights into the mechanisms of how human tumors acquire genomic amplifications as major drivers of oncogenic transformation

29/10/2021 | With this award the German Society for Cell Biology (DGZ) acknowledges each year outstanding cell biological research with a focus on cell culture or the use of cell cultures.

27/10/2021 | On October 27, 2021 the Faculty of Medicine invites to the second Scientific Career Day. The focus this year is on the topic of the leadership culture of tomorrow.

29/09/2021 | Many thanks to our guest speakers for their outstanding contributions on the forefront of 25 years of progress in molecular medicine, our participants, the Leopoldina, the Fritz Thyssen Foundation and our internal collaborators for their support.

18/09/2021 | Cologne Researchers of the Faculty of Medicine and the University Hospital Cologne uncovered a conserved, MAPK/IRF1-mediated inflammatory response in tumors that undergo stemness- and senescence-associated reprogramming.

18/09/2021 | New study demonstrates the necessity of a scrutinized molecular view of the pleiotropic functions of omega-3-and omega-6-polyunsaturated fatty acids as molecular culprits or benefactors of life style diseases over the course of the lifespan before they are included in legitimate dietary recommendations

17/09/2021 | On Sept. 17, 2021, PD Dr. Özlem Türeci and Prof. Dr. Uğur Şahin, the founders of the biotech company BioNTech and developer of the first approved mRNA-based Corona vaccine were honored in the Historic City Hall of the City Cologne. They signed the Golden Book of the City of Cologne and the University of Cologne and were awarded with the Honorary Doctorates from the Faculty of Medicine of the University of Cologne.

16/09/2021 | Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in the embryonic phase - reported by researchers from the DZNE, the Faculty of Medicine and the CMMC at the University of Cologne and the University Hospital Cologne

30/07/2021 | The attachment of the small protein ubiquitin to other proteins (ubiquitination) regulates numerous biological processes, including signal transduction and metabolism.

23/07/2021 | The CRU 329 is starting the second funding period with a funding volume of over five million euros until 2024 on `Molecular mechanism of podcyte diseseas - Nephrology on the way to precision medicine`.

08/07/2021 | A slower renewal turnover of aged skin and its hair follicles may be caused by the decreased elasticity of skin tissues surrounding the stem cells / New insights into the causes of aging published in ‘Nature Cell Biology’

30/06/2021 | The European Research Council is among the most important European institutions promoting pioneering research. Biologist Maria Leptin will become the new Chair of the ERC’s Scientific Council.

25/06/2021 | Scientists from the University of Cologne found that the balance status of proteins (protein homeostasis) of germline cells influences protein aggregation in other tissues by long-distance signaling | Publication in ‘Science Advances’

16/06/2021 | The study of an interdisciplinary Cologne Research Team provides a rational for pharmacologically targeting the NLRP3 inflammasome and associated cytokines in severe cases of COVID-19. The data will help to evaluate immunogenicity of S-protein-based vaccine constructs with regard to stimulation of innate immune signaling.

12/06/2021 | We extend our sincere condolences to his family and friends.

18/05/2021 | Cologne reseachers have now developed an approach that allows them to show that neurons that are supposedly the same are actually very different: they not only sense different hormones for the body's energy state, but also have a different influence on food intake.

01/05/2021 | As of May 2021 Silvia von Karstedt will take up the professorship for Dynamics of Cancer and Immune Systems anchored in the Department of Translational Genomics and based at CECAD.

06/04/2021 | Iron-dependent cell death ferroptosis and cell death by oxidative stress can be activated in small cell lung cancer, and be induced by two drugs / publication in ‘Nature Communications’

27/03/2021 | Björn Schumacher and Thomas Krieg (Medical Faculty, University of Cologne) launched a special issue in the Journal of Investigative Dermatology focusing on aging skin and thereby highlighting novel therapeutic concepts to combat aging-associated skin diseases.

11/03/2021 | The CMMC is pleased to announce the three scientists of the Medical Faculty (University of Cologne) awarded with the CMMC CAP Funding. The three awardees are: Phuong-Hien Nguyen, Joahnnes Brägelmann and Sebastian Brähler.

03/03/2021 | Two Cologne scientists have developed a method that can determine an organism’s biological age with unprecedented precision. The researchers expect new insights into how the environment, nutrition, and therapies influence the aging process.

22/02/2021 | The International Society for Regenerative Biology provides a new opportunity to actively exchange the latest ideas and to foster potential cross-disciplinary collaborations among Regenerative Biology and Clinical Translation: VIRTUAL MEETING April 8-9, 2021

18/02/2021 | New consortium of research institutions VACCELERATE will coordinate vaccine trials in the European Union. The long-term goal is to strategically plan and carry out vaccine trials in all EU and EU-associated countries

05/02/2021 | In total, more than 260 participants attended the CMMC Annual Retreat 2021 participating in either all or selected program parts offered over the course of the 3-day CMMC Annual Retreat 2021.

01/02/2021 | Study provides evidence for involvement of the genes FANCM, MSH6, and NF1 in addition to the already known breast cancer risk genes. The German Familial Breast & Ovarian Cancer Consortium Univ. Hopsital of Cologne), coordinated by Prof. R. Schmutzler, contributed nearly 30 percent of all familial samples.

20/01/2021 | With an epitope-based immunization, scientists at Cologne University Hospital / University of Cologne and the German Center for Infection Research (DZIF) have now described a new vaccination strategy against S. aureus

19/01/2021 | Based on an intensive reseach, Brundhilde Wirth and her team have found a patient affected by a newly investigated disease gene VWA1, causing recessive hereditary motor neuropathy. Identification opens up new therapeutic strategies

11/01/2021 | A new clinical study at the University of Cologne and Cologne University Hospital is investigating whether a ketogenic diet has a positive effect on patients with polycystic kidney disease. The trial is funded by the American PKD Foundation (polycystic kidney disease).

18/12/2020 | Cologne University Hospital/University of Cologne, University of Marburg, the German Center for Infection Research (DZIF) and Boehringer Ingelheim announcing the initiation of Phase 1/2a clinical investigation of BI 767551, a new SARS-CoV-2 neutralizing antibody.

30/11/2020 | The SFB 1451 focusing on motor control is under the leadership of the Faculty of Medicine at the University of Cologne starting in 2021.

25/11/2020 | published annually by Clarivate Analytics based on data from the publication database ‘Web of Science’. In total seven researchers of the University of Cologne are at the top in this ranking - an indicator for excellent scientific achievements.

18/11/2020 | providing him the option to translocate his research activities to the University of Cologne. The Medical Faculty has started the recruitment negotiations.

04/11/2020 | developed by the funding initiative C.A.S.E. presents career paths beyond the classical activities as physician & highlights the academic developments

12/10/2020 | The research team led by Björn Schumacher (University of Cologne) uncovers a role for H3K4me2 in coordinating the recovery of protein biosynthesis and homeostasis required for developmental growth and longevity after DNA damage. This discovery may enable the development of therapeutic approaches for treating premature aging disorders.

03/10/2020 | BioRiver awards three biotech start-up companies PerAGraft (Aachen) - Dermanostic (Düsseldorf) - CASC8 (Belgium) for their innovative and diagnostic approches.

30/09/2020 | The two awards are highlighting the outstanding scientific contribution of Jens C. Brüning´s research activities and groundbreaking finding that have increased the knowledge of diabetes as well as obesity and metabolic diseases

28/09/2020 | An international research team led by Sabine Eming (Univ. of Cologne) and Sara Wickström (Univ. of Helsinki) has shown that Rictor, a protein that helps to regulate the growth, energy, and oxygen consumption of cells, plays a key role in the cellular metabolism and longevity of hair follicle stem cells in mice.

16/09/2020 | The research group around Brunhilde Wirth at the Institute for Human Genetics, the Center for Molecular Medicine Cologne (CMMC) and the Center for Rare Diseases at the University Hospital Cologne has now identified mutations in the GBF1 gene that cause a new type of motor neuropathy.

27/08/2020 | The Federal Ministry of Education and Research (BMBF) is supporting a research project at the Cologne University Hospital and the Medical Faculty with over 400,000 Euros led by Prof. Dr. Bernhard Schermer between the Dept. II of Internal Medicine and the Institute for Virology in affiliation with the CMMC at the University Hospital Cologne

04/08/2020 | providing a potential new target for personalized medicine, say scientists at the University of Cambridge and CMMC - University of Cologne

29/07/2020 | The German Research Foundation (DFG) has approved the extension for funding of the CRC/SFB 1218 "Regulation of cellular function by mitochondria" for additional four years until 2024.

29/07/2020 | The German Research Foundation (DFG) has approved the extension of funding of the CRC 1218 "Regulation of cellular function by mitochondria" for additional four years until 2024.

22/07/2020 | The study of Cologne Scientits led by Hamid Kashkar (CECAD and CMMC) provides genetic evidence for a requirement of mitochondrial respiration in vascular endothelial cells for neoangiogenesis during development, tissue repair and cancer.

09/07/2020 | A team of researchers led by Prof. Florian Klein (Cologne University Hospital) and the German Center for Infection Research (DZIF) has further elucidated how these antibodies develop and has isolated potent SARS-CoV-2 neutralizing antibodies.

08/07/2020 | Together with other internationally renowned European scientists, EMBO has accepted the molecular biologist Prof. Dr. Thorsten Hoppe from the Institute of Genetics, the Cluster of Excellence for Ageing Research CECAD and the Center for Molecular Medicine Cologne at the University of Cologne as a new member.

02/07/2020 | Prof. Dr. Thomas Benzing re-elected as CMMC Chair for the next term of 3 years. As Vice-Chairs Prof. Dr. Guenter Schwarz was re-elected and Prof. Dr. Sabine Eming was elected for the first time.

04/06/2020 | In a cooperative approach the team around Thomas Langmann (Laboratory of the Exp. Immunology of the Eye at the Center for Ophthalmology and the CMMC) together with the team of Michael Schramm (Inst. of Med. Microbiology, Immunology and Hygiene) at the Univ. Hospital of Cologne and the Univ. of Cologne has identified a new mechanism of damaging immune activation in the eye.

12/05/2020 | by the research team led by Prof. Thomas Benzing: ultraresolution microscopy together with mathematical modelling provides an experimentally validated model of the kidney filtration barrier.

11/05/2020 | Life Science Research: Career planning after the Master's degree or doctorate in the life science industry

29/03/2020 | in astrocytic perivascular processes highlighting a crucial role of glial cells in enabling vascular remodelling

20/03/2020 | With their findings Wilhelm Stoffel and his research team discovered a previously unrecognized membrane-structure-based molecular link between nutrient ω3-and ω6-PUFAs,

18/03/2020 | Phenotyping of model organisms and diagnostics of cancer: K. Bozek's research aims are to establish methods and approaches allowing for broad, data scientific use of visual data in biology and medicine.

16/03/2020 | In light of the increased spread of the Coronavirus (SARS-CoV-2), the CMMC has implemented strict measures in an effort to slow down the infection rate and to protect the health and safety of our members and associates.

27/02/2020 | presented by Alessandro Annibaldi - new CMMC Junior Research group

12/02/2020 | Small variations in the composition of a cell can radically change its function and cause diseases such as diabetes, cancer or neuronal dysfunction.

06/02/2020 | presented by Simon Poepsel - new CMMC Junior Research Group Leader

01/02/2020 | identified by the research group led by Florian Klein at the Inst. of Virology, Univ. Hospital of Cologne & the University of Cologne and the German Centre for Infection Research (DZIF).

23/01/2020 | organized by the Depts. of Internal Medicine II and III, Univ. Hospital of Cologne in collaboration with the CMMC, CECAD and Stiftung der Cellitinnen e.V.

14/01/2020 | presented by Robert Hänsel-Hertsch – new CMMC Junior Research Group Leader

29/11/2019 | Third-party project "Cell death in immunity, inflammations and diseases" (CRC 1403) funded with 13 million euros for four years

22/11/2019 | The current study hypothesises that these strategies may have driven the counter-evolution of pyroptosis to secure cellular death as a host defence mechanism.

02/10/2019 | to establish an internationally visible research group as independent leaders at the Center for Molecular Medicine Cologne.

09/08/2019 | A collaborative study performed by international research groups led by Sabine Eming (Dept. of Dermatology - University Hospital Cologne) identified a new molecular mechanism causing dry and scaly skin frequently associated with atopic dermatitis, diabetes mellitus or skin ageing.

01/08/2019 | Preparation of the new funding period with the site visit of the External Scientific Advisory Board (SAB) from Nov. 25-26, 2019.

30/07/2019 | Molecular mechanics in the skin of mice are driven by polarity genes as a team led by Sandra Iden of the Cluster of Excellence CECAD and the CMMC reports in ‘Nature Communications’.

21/06/2019 | Research group of Brunhilde Wirth demonstrates that a combined therapy of nusinersen (SMN-ASOs) and neurocalcin delta (NCALD) ASOs improves protection against spinal muscular atrophy (SMA) compared to nusinersen alone.

04/06/2019 | Medical research at the University of Cologne will be enhanced by two large-scale third-party funded projects.

18/05/2019 | A collaborative study by research groups from the Cluster of Excellence CECAD and the Center for Molecular Medicine Cologne (CMMC) at the the University of Cologne,

14/05/2019 | for her groundbreaking research in the field of spinal muscular atrophy.

12/04/2019 | – new experimental strategy described by the CMMC team lead by Álvaro Rada Iglesias

21/03/2019 | indicating that restoring histone acetylation levels in cardiomyocytes by histone acetylases inhibition prevents the sphinganine-induced DNA damage and functional decline both in vitro and in vivo.

22/01/2019 | January 19, 2019

13/12/2018 | by the research team of Dr. Leo Kurian, heading a NRW Stem Cell Network Junior Research Group at the CMMC.

29/06/2018 | The research team of Prof. Dr. Brunhilde Wirth, working at the Institute of Human Genetics and the Center for Molecular Medicine Cologne, succeeded

01/06/2018 | Dr. Argyris Papantonis, Junior Group Leader for Chromatin Systems Biology at the CMMC will be co-coordinating a large German consortium on 3D genome architecture.

15/05/2018 | The RTG supported by the CMMC investigates common inflammatory processes and cellular reactions to cardiovascular diseases.

27/04/2018 | was uncovered by the Chromatin Systems Biology research group of Dr. Argyris Papantonis at the CMMC, and sheds new light onto how cell senescence is established.

20/02/2018 | Martin Peifer and his team analyzed whole-exome sequencing data of eight chronic lymphocytic leukemia (CLL) patients that developed resistance upon BCL2-inhibition by venetoclax

24/01/2018 | A collaborative effort between the research groups of Brunhilde Wirth (Inst. of Human Genetics (Univ. Hospital of Cologne) and the CMMC and Giovanni Stevanin (Neurogenetics Inst., INSERM) succeeded to identify a novel mutation in the gene CHP1 as a novel cause of Cerebellar Ataxia.

22/01/2018 | During the symposium highly challenging aspects of geriatric care have been discussed by experts in the field, including intensive care, emergency medicine and cardiovascular disease management of older adults.

16/01/2018 | highlighting the power of genetic modifiers in Spinal Muscular Atrophy (SMA) from the Faculty of Medicine, University of Cologne on January 12, 2018 .

20/12/2017 | The Interdisciplinary Program Molecular Medicine (IPMM) at the University is aimed at outstanding research-oriented medical and life science graduates.

19/12/2017 | More than 200 million people worldwide suffer from chronic kidney diseases (CKD). Glomerular disorders account for the majority of cases of CKD.

04/11/2017 | of patients reported by the teams of Sebahattin Cirak (Dept. of Pediatrics, Univ. Hospital of Cologne and the CMMC), Andrew Crosby and Emma Baple (University Exeter, UK).

25/10/2017 | to further promote his research to uncover the transcriptional regulatory principles of mammalian embryogenesis and human congenital disease.

17/10/2017 | A direct implications for multi-exon skipping strategies for Duchenne muscular dystrophy (DMD). A breakthrough has been achieved in the understanding why patients benefit so variably from molecular therapies for muscular dystrophies in clinical practice.

26/09/2017 | Scientists in the research groups of Roman Thomas and Martin Sos at Cologne University Hospital and University of Cologne have tested the effects of more than 1,500 substances on different kinds of cancer cells.

23/07/2017 | Translating basic concepts into regenerative therapy” taking place from Oct. 15 - 17, 2017 organized by the CMMC at the Medical Campus, University of Cologne.

10/07/2017 | To increase awareness towards alternative careers in non-academic sectors of life science companies the CMMC hosted this event for the third time on July 05, 2017.

07/07/2017 | aming at increasing their awareness towards UV exposure as a primary preventive strategy to decrease skin cancer rates in adults.

22/06/2017 | Sabine Eming (University Hospital of Cologne, CMMC and CECAD) together with her colleagues Thomas Wynn (National Institutes of Health, USA) and Paul Martin (University of Bristol, UK) summarize the state of the research and emerging concepts that may expand therapeutic perspectives by addressing the role of key inflammatory and metabolic processes in tissue-regenerative responses.

09/06/2017 | Individual excellence is at the core of scientific progress and must be rewarded – that is why the University of Cologne awards Research Prizes to excellent researchers.

08/06/2017 | The CMMC welcomed students of the Master Program Cancer, Stem Cells and Developmental Biology of the Utrecht University to the Mini-Symposium "CMMC Research Insights“ on June 07, 2017

29/05/2017 | This Forschungskolleg, chaired by Prof. Christiane Bruns and Prof. Christian Reinhardt, will promote the career development of the so-called Clinician Scientist.

27/05/2017 | Healthcare professionals were invited to gain insight into the latest research findings and the developments related to the translation into everyday clinical practice.

05/05/2017 | Dr. Herling and Prof. Abken leading the Cologne project successfully synergize lymphoma biology Herling´s research group) and the facilities of applied T-cell immunology (Abken´s research group) on the model of T-cell prolymphocyte leukemia (T-PLL).

27/03/2017 | The team of Alvaro Rada-Iglesias has discovered that a group of DNA regulatory sequences, called poised enhancers, are essential for the induction of genes with major roles during brain development.

10/03/2017 | The group of Brunhilde Wirth (Inst. of Human Genetics, Univ. Hospital of Cologne and the CMMC has, together with the group of Henry Houlden (London), identified mutations in the VAMP1 gene as cause of this disorder.

09/03/2017 | This year the meeting covering "Frontiers in Matrix Biology" takes place in Cologne in cooperation with the CRC 829 and the Center for Molecular Medicine Cologne.

02/03/2017 | The prize is one of the highest awards in German cancer medicine and has been awarded to Prof. Dr. Michael Hallek for his outstanding scientific achievements in the field of chronic lymphocytic leukemia (CLL).

20/02/2017 | Jay Gopalakrishnan, Olaf Utermöhlen and Martin Krönke from the CMMC, the Inst. of Med. Microbiology, Immunology & Hygiene and the DZIF reprogrammed human skin cells into neural stem cells and used these to develop a 3D experimental model that depicts early brain development.

27/01/2017 | The research team of Brunhilde Wirth, Director of the Institute for Human Genetics at the University Hospital of Cologne leading a CMMC resarch group identified Neurocalcin Delta (NCALD) as a protective modifier gene for Spinal muscular atrophy (SMA).

23/01/2017 | the fastest-growing type of cancer and the most fatal skin disease. Sandra Iden and her team at CECAD Cologne supported by the CMMC and the CRC 829 investigated the influence of the surrounding tissue on the formation and growth of tumor cells.

12/01/2017 | connect complex diseases and cell type-specific enhancer maps. The team of Rada-Iglesias has recently implemented a bioinformatic toolkit called GARLIC.

10/01/2017 | aims to demonstrate the potential of interdisciplinarity and multidimensionality with the ultimate scope of defining new perspectives in the management and care of older individuals.

22/12/2016 | was developed by the Chromatin Systems Biology research Group of Dr. Argyris Papantonis at the CMMC, that allows for a new understanding of its structure-to-function relationship.

16/12/2016 | to dissect cellular heterogeneity based on a highly sensitive and specific strategy. The research team of Alvaro Rada-Iglesias, leading a Junior Research Group at the Center for Molecular Medicine Cologne,

14/12/2016 | The Interdisciplinary Program Molecular Medicine (IPMM) at the University is aimed at outstanding research-oriented medical and life science graduates.

09/12/2016 | - an Organization for PhD Education in Biomedicine and Health Sciences in the European System associated with numerous European biomedical and health science faculties and institutions.

04/12/2016 | shares with other colleagues in an interview with Cell Stem Cell the experience to set up the own lab and the challenge to publish the group’s first paper.

28/11/2016 | Florian Klein’s main goal is to improve HIV therapy with the help of antibodies and to develop a HIV vaccine. His research on a new generation of broadly neutralising antibodies has found worldwide recognition: the German Center for Infection Research (DZIF)

23/11/2016 | and will receive a further four years of funding by the DFG. The CRC 829 chaired by Prof. Carien Niessen was positively evaluated

21/11/2016 | from Nov. 23 - 25, 2016 organized by the members of the CECAD/CMMC Proteomics Facility and Proteomics Facility of the MPI for Biology of Ageing.

08/11/2016 | Researchers of the Cluster of Excellence CECAD and the Center of Molecular Medicine Cologne at the University of Cologne showed that RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation.

28/10/2016 | The research group of Brunhilde Wirth at the Institute of Human Genetics (Univ. Hospital of Cologne) and the Center for Molecular Medicine Cologne (CMMC) has succeeded to identify mutations in a gene called PIEZO2 that cause a new type of muscular atrophy by lack of proprioception.

26/10/2016 | Of fly, mouse and man - the research team led by Sabine Eming, Dermatologist at the Univ. Hospital of Cologne and Principal Investigator at the CMMC and CECAD Cologne, identified unique functions of target of rapamycin (TOR) signaling in skin morphogenesis and epidermal barrier formation.

25/10/2016 | A new perspective for the development of therapeutic approaches for the treatment of inflammatory diseases. The team of Dr. Argyris Papantonis discovered in collaboration with groups from the Universities of Oxford (UK), Aachen (DE), and the Erasmus Medical Center (NL) this novel mechanism published in Genome Research.

10/10/2016 | for the development of new treatment methods. Researchers at the MPI for Biology of Ageing, the CMMC, the CECAD Cologne and the Institute for Genetics of the University of Cologne have now gained new insights into the underlying cellular mechanisms. Their findings could lead to the development of new treatment methods.

29/09/2016 | Bernhard Schermer - principal investigator of the CMMC Research Project C 9 - has been awarded with the Franz-Volhard-Prize given by the German Society of Nephrology in recognition of his outstanding research on the pathogenesis of cystic kidney diseases.

20/08/2016 | Leo Kurian received the Young Investigator Award 2016 for his outstanding research from the German Stem Cell Network.

08/08/2016 | The team of scientists led by Brunhilde Wirth, Principal Investigator at the CMMC and director of the Institute for Human Genetics, uncovered unknown cellular mechanisms that will lead to new therapeutic strategies for the treatment of spinal muscular atrophy. This outstanding scientific contribution has been awarded as highlight by the Am J Hum Genet. free access for to the publication until Oct. 21, 2016: http://authors.elsevier.com/a/1TedAgeWinGf

04/08/2016 | A potential tool for novel targeted therapeutic strategies. Diffuse large B cell lymphoma - the most common and aggressive blood cancer in the Western world - remains a clinical challenge. Christian Reinhardt and Christian Pallasch highlighted

03/08/2016 | The research team led by Sandra Iden, Principal Investigator at the CMMC and CECAD Cologne, uncovered a key role for the polarity protein  Par3 

31/07/2016 | - an important finding for the implementation of clinical trials. To specify the natural disease progession of Duchenne Muscular Dystrophy (DMD) patients and the mutations in the Dystrophin gene Sebahattin Cirak, leading a DFG Emmy Noether research group at the CMMC, and his international

24/07/2016 | CMMC scientists offer courses and lectures related to aging research in the CSS - organized by the International Office of the University of Cologne.

15/06/2016 | In the newly established CRC 1218 nineteen project leaders from the University of Cologne, the University Hospital Cologne, the Max Planck Institute for Biology of Ageing and the Max Planck Institute for Metabolism Research in Cologne have teamed up to study how mitochondria influence activity, differentiation and survival of the cell.

08/06/2016 |  A basic cell biological question of how centriolar and ciliary lengths are regulated has remained unknown. Anand Ramani and Li Ming Gooi, members of Jay Gopalakrishnan´s

03/06/2016 | Aleksandra Trifunovic (Principal Investigator at the Cluster of Excellence CECAD) will coordinate the REMIX project (REgulation of MItochondrial gene eXpression).