News

Another top position for corneal transplants

06/09/2024 | The Center for Ophthalmology at the University Hospital of Cologne has once again maintained its leading position in the field of corneal transplants in Germany in 2023.

New Mechanisms Identified for Muscle Repair

04/09/2024 | Scientists at the University of Cologne, in collaboration with international partners, have developed a new experimental setup to induce sustained muscle contraction in nematodes using blue light alone.

How gene regulation changes over a lifetime

03/09/2024 | Scientists at the University of Cologne have discovered that coordination between basic cellular processes is lost with increasing age / publication in ‘Nature Aging’

Corneal transplantation: Research on donor-induced graft acceptance

29/08/2024 | Follow-up funding for ophthalmology: Prof. Dr. Felix Bock (Cologne), together with Prof. Dr. Alexander Steinkasserer (Erlangen), has received follow-up funding from the German Research Foundation (DFG) for further research into donor-induced graft acceptance after corneal transplantation.

Two proteins identified as potential targets to improve ALS symptoms

26/08/2024 | University of Cologne scientists have found that the protein histone H1.2 and the enzyme PARP1 could be potential therapeutic targets to decrease neurodegeneration in amyotrophic lateral sclerosis (ALS) / publication in ‘Cell Reports’

Artificial intelligence improves lung cancer diagnosis

26/08/2024 | University of Cologne - New AI-based digital platform enables extremely fast and accurate analysis of tissue sections from lung cancer patients / publication in ‘Cell Reports Medicine’

Prof. Fink new member of the Leopoldina

20/08/2024 | Prof. Dr. Gereon R. Fink is honored as one of the most cited German neuroscientists for outstanding scientific achievements in the neurosciences.

Unique mechanism protects pancreatic cells from inflammation in mice

31/07/2024 | The results of the new study could have significant implications for advancing our understanding of diabetes / publication in ‘Molecular Metabolism’

Apply now for the CCSP-Program at the Medical Faculty of the University of Cologne

17/07/2024 | The Medical Faculty of the University of Cologne offers positions in the Cologne Clinician Scientist Program (CCSP), a training program for Clinician Scientists with a strong focus on translational and / or clinical research.

Aleksandra Trifunovic accepted as a new member of the European Molecular Biology Organization (EMBO)

09/07/2024 | Together with other internationally renowned European scientists, the European Molecular Biology Organization (EMBO) has accepted the molecular biologist Professor Dr Aleksandra Trifunovic from the Institute of Mitochondrial Diseases and Ageing at the University of Cologne’s Faculty of Medicine, the CMMC Center for Molecular Medicine Cologne and the CECAD Cluster of Excellence for Aging Research as a new member.

DFG approved: Funding for new CRC 1678 on mRNA Research and Extension for the Mito-CRC 1218

10/06/2024 | The German Research Foundation (DFG) has approved a new Collaborative Research Center in mRNA research and extended funding for the CRC 1218 on mitochondria

The body’s own lipids affect mental disorders: Can specific inhibitors help?

07/06/2024 | A genetic disorder leads to an increase in bioactive lipids in the brain promoting mental disorders. New study shows that treatment with an enzyme inhibitor that prevents the activation of lipids can restore balance and alleviate symptoms.

June 3-7, 2024: Diversity Week at the University of Cologne

29/05/2024 | The University of Cologne is holding events to promote equal opportunities - organized by the Vice Rectorate for Anti-Discrimination, Equal Opportunities and the Equal Opportunities Unit and cooporating partners.

Data-driven characterisation of genetic variability in disease pathways and pesticide-induced nervous system disease

17/05/2024 | The study highlights the importance of the integration of spatial and genetic data for the prediction of at-risk populations and the guidance of future research and policy. Publication in "Environ Health Perspect"

How aging clocks tick

06/05/2024 | Two scientists from the University of Cologne have discovered that aging clocks are based on random events / publication in ‘Nature Aging’

Warmest congratulations to Professor Stoffel from the CMMC Family

30/04/2024 | We are pleased to extend our warmest congratulations to you on the occasion of your birthday. We recognize the dedication of your life to the pursuit of knowledge and scientific excellence.

Once food is in sight, the liver is activated

26/04/2024 | The brain sends signals to the liver earlier than previously assumed, which then adapts the sugar metabolism - publication in ‘Science’.

ERC Advanced Grants for the CECAD and CMMC researchers Jens Brüning and Thorsten Hoppe

11/04/2024 | Metabolism researcher Jens Brüning and geneticist Thorsten Hoppe, both working group leaders at the Cluster of Excellence for Aging Research CECAD and the Center for Molecular Medicine Cologne, receive European Research Council awards.

Innovative Biomaterial Breakthroug: Development of Theragenerative Biomaterial with Antibacterial, Antiosteosarcoma, and Osteoinductive Properties

10/04/2024 | An international research team, led by PD Dr. Hajar Maleki (University of Cologne), has developed a novel approach to bone tissue engineering, that has the potential to significantly advance the restoration of damaged bone tissues in post-surgery osteosarcoma treatment.

Fuelling nerve cell function and plasticity

08/04/2024 | New finding from scientists at the University of Cologne’s CECAD and CMMC discloses how mitochondria control tissue rejuvenation and synaptic plasticity in the adult mouse brain / publication in ‘Neuron’

Research laboratories of the Center for Molecular Medicine Cologne on level 1 awarded the Green Lab certificate

08/04/2024 | After a 9-month certification process, four research groups at laboratory level 1 of the Center for Molecular Medicine Cologne (CMMC research building) have received the sustainability certificate awarded by the non-profit organization My Green Lab - with the highest certification level "Green". In the initial assessment, the CMMC research groups led by Dr. Hänsel-Hertsch, Dr. Simon Pöpsel, Dr. Debora Trentini and PD Dr. Catherin Niemann had already achieved bronze status.

Eating, socializing or exploring: How the brain switches between different behaviors

18/03/2024 | Project involving the University of Cologne gives insights into a key brain function / publication in ‘Nature Neuroscience’

Researchers develop artificial building blocks of life

08/03/2024 | For the first time, scientists from the University of Cologne (UoC) have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory. They could be used as artificial nucleic acids for therapeutic applications / publication in ‘Journal of the American Chemical Society’

Keeping the immune system in check

07/03/2024 | Researchers from the University of Cologne (UoC) have discovered a regulatory mechanism that prevents an excessive and harmful immune response / publication in ‘Nature Communications’

New strategy for safer CAR T cell therapy in lymphomas

16/02/2024 | Scientists at University Hospital Cologne have developed a procedure in the laboratory that effectively fights affected cells in lymphoma cancer without harming healthy immune cells, a common issue with comparable therapies / publication in ‘Cell Reports Medicine’

The German Cancer Aid Prize 2023 was awarded to Reinhard Büttner, Jürgen Wolf and Roman Thomas -

06/02/2024 | three scientists from Cologne - in recognition of their outstanding contributions to lung cancer diagnostics and therapy, specifically within the framework of the "National Network Genomic Medicine (nNGM) Lung Cancer", which they initiated.

Getting to the root of the illness

01/02/2024 | DNA and RNA research is revolutionizing pharmaceutics: New drugs are being developed faster and at a lower cost, and they are effective against previously incurable diseases.

March 18-22: Cologne Spring School for Medical Humanities 2024

31/01/2024 | Perspectives on Health, Wellbeing and Diversity - This inter- and transdisciplinary 5-day Spring School is aimed at advanced students and doctoral candidates to promote innovative dialog between medicine and the humanities.

Treating tuberculosis when antibiotics no longer work - New antibiotic molecules identified

02/01/2024 | An international research team led by Jan Rybniker has identified several substances that have a dual effect against tuberculosis. These substances reduce the pathogenicity of the bacteria responsible for the disease in human immune cells and boost the activity of conventional antibiotics. The findings were published in 'Cell Chemical Biology'.

How the first contact of the virus influences the immune response to new SARS-CoV-2 variants

08/12/2023 | Cologne scientists decipher how the antibody response of our immune system reacts to a coronavirus infection and prepares for future infections / Publications in ‘Immunity’ and ‘Science Immunology’

Philipp Schommes honored with Else Kröner Clinician Scientist Professorship for Outstanding Patient Care and Research Synergy

06/12/2023 | With the € 1.1 Mio. Professorship Funding from Else Körner Foundation, Philipp Schommer is dedicated to further advance antiviral therapies and vaccines. Further information: Schommers Laboratory of Antiviral Immunity

New Cutting-Edge Ophthalmology CRC and Continued Funding for the CRC in Cell Death

29/11/2023 | The German research Foundation (DFG) has approved a Collaborative Research Centre (CRC) in the field of ophthalmology / CRCs on cell death and Arctic climate research are being further funded.

New antibodies neutralize resistant bacteria

02/11/2023 | Broadly neutralizing antibodies are already being used to fight viruses. This approach could also help to treat infections with multi-resistant bacteria in the future / publication in the renowned journal ‘Cell’

ERC Synergy Grant for Björn Schumacher: bats as a guide to extend healthspan

26/10/2023 | The ERC BATPROJECT "Learning from Bats: New strategies to extend healthspan and improve diseases resistancce". European Research Council (ERC) is funding the project ‘BATPROTECT’ with 11.9 million euros over a period of six years

Plant chloroplasts promise potential therapy for Huntington’s disease

04/10/2023 | In planta expression of human polyQ-expanded huntingtin fragment reveals mechanisms to prevent disease-related protein aggregation/ new research reported in “Nature Aging” may have found a way to “copy” the mechanism for application in human cells

From concepts to Clinic: a New Era of Nucleic Acid Therapeutics - The CMMC Symposium 2023

21/09/2023 | addressed these challenges and successfully contributed to intensify the interdisciplinary exchange. We were delighted to welcome over 320 participants.

Essential cell death-regulating mechanisms important for recovery from SARS-CoV infection and skin injury discovered

27/07/2023 | University of Cologne Scientists discover that cleavage of the protein cFLIP is crucial to limit cell death and promote tissue regeneration / Publication in Science Advances

Immune checkpoint molecule B and T-lymphocyte attenuator (BTLA) is important for the control of inflammation of glomerulonephritis

28/06/2023 | In this study, Cologne researchers demonstrate a differential expression of BTLA on renal immune cells during glomerulonephritis. indicating that the immune checkpoint molecule BTLA has great potential to restrain T-cell mediated kidney inflammation.

Thomas Benzing - Sabine Eming - Guenter Schwarz - elected as Chairperson and Vice Chairpersons of the CMMC

19/06/2023 | All three elected candidates accepted their election and thanked the CMMC Members for their trust. Together with the Scientific Coordinators of the three Research Areas the elected chairpersons are looking forward to further advance the scientific and structural development of the CMMC.

Deeply saddened by the news that our friend and colleague Konstantin Belostotski has passed away

02/06/2023 | With deep sadness, we received the news of the loss of our dear friend and colleague Konstantin Belostotski.

Defective sugar chains trigger genetic syndrome

26/05/2023 | Cologne researchers identify a novel chaperonopathy causing altered protein O-glycosylation. This discovery will promote a better understanding of the role of complex O-glycans in human health and disease.

Second Funding Period Approved - The TRR 259 "Aortic Diseases" was awarded a DFG grant of about 14 Mio. € for its second funding period (2023-2027)

22/05/2023 | With this extension, the members of the TRR 259 are excited to continue cutting-edge research into aortic diseases in Cologne, Düsseldorf, and Bonn.

The German Research Council (DFG) awards the extension CRC 1399 “Mechanisms of drug sensitivity and resistance in small cell lung cancer”

22/05/2023 | Funding for the worldwide largest research consortium on Small Cell Lung Cancer extended for four additional years.

May 25 -26, 2023: Announcement Leopoldina Symposium "The ageing eye"

22/05/2023 | Unmet medical needs, societal implications and future therapeutic perspectives.

Mai 09, 2023: Announcement - FOR 2722 Symposium "Oxygen, metabolismus and extracellular matrix"

08/05/2023 | To celebrate the start of the second funding period the FOR 2722 is hosting an International Symposium.

Ageing-associated changes in transcriptional elongation influence longevity - Publication in ‘Nature’

13/04/2023 | In a large joint study, researchers of the University of Cologne, the Cologne Max Planck Institute for Biology of Aging (MPI) and the University of Göttingen have shown that across the animal kingdom with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers and that with dietary restrictions, these processes could be reversed.

A key mechanism that controls human heart development discovered

30/03/2023 | Researchers of the University of Cologne describe that the competence for the future cardiac fate of human embryonic stem cells (hESCs) is preset in pluripotency by a specialized mRNA translation circuit controlled by RBPMS l published in Science Advances

Researchers discover a way to fight the aging process and cancer development

26/03/2023 | demonstrating that the DREAM complex functions as conserved master regulator of somatic DNA-repair capacities.

Brunhilde Wirth was honored with the highest-ranking prize of the Deutsche Gesellschaft für Muskelkranke

25/03/2023 | On March 23, 2023 she receives the national prize the "Duchenne-Erb Prize" in recognition of her life's work as a human geneticist and her outstanding scientific achievements: the elucidation of the genetic cause of spinal muscular atrophy (SMA), the discovery of genetic factors that protect against SMA and the associated cellular pathomechanisms.

April 18 -19, 2023: TMF-Annnual Congress "The future of medicine - Where are omics, digitalization and social change leading?

23/03/2023 | The 14. Annual Congress of the Technology and Methods Platform for Networked Medical Research (TMF) will focus on the opportunities, risks and challenges of genomic medicine.

Please find more CMMC news in our news archive.