Overview of completed dissertations
2022
Adamo, Christin (M.Sc. in Biomedical Sciences)
Project Title: New mechanisms of fibrillin dependent fibrosis
Supervisor: PD Dr. Gerhard Sengle - Institute for Biochemistry II
Breuer, Saida (M. Sc in Molecular Nutritional Science)
Project Title: Causes and avoidance of hypothalamic Dysfunction in the offspring of obese mothers
Supervisor: Prof. Dr. Jörg Dötsch - Clinic and Polyclinic for Paediatric and Adolescent Medicine
Daimagüler, Hülya-Sevcan (M. Sc. in Molecular and Applied Biotechnology)
Project Title: Identification and functional assessment of novel neuromuscular disease-causing genes
Supervisor: Dr. Sebahattin Cirak - Department of Pediatrics / CMMC
Delle Vedove, Andrea (Diploma in Medicine and Surgery)
Project Title: Identification and Functional Assessment of Novel Neuromuscular Disease-Causing Genes
Supervisor: Prof. Dr. Brunhilde Wirth - Institute for Human Genetics
Jiang, Qu (M.Sc. in Medicine)
Project Title: The oncogenic role of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia
Supervisor: PD Dr. Marco Herling - Clinic I of Internal Medicine
Knoke, Kristin (M. Sc. in Biology)
Project Title: The crosstalk of vitamin D and iron metabolism in innate host responses against intracellular pathogens
Supervisor: Prof. Dr. Mario Fabri - Clinic and Policlinic for Dermatology and Venerology
Nikiforov, Anastasia (M.Sc. in Molecular Cell Biology)
Project Title: Deciphering the role of scaffolding protein NEDD9 in pathogenesis and therapy of EGFR-driven lung adenocarcinome with focus on stromal tumor microenvironment
Supervisor: Dr. Tamina Seeger Nukpezah - Clinic I of Internal Medicine
Thomalla, Daniel (M.Sc. in Biological Sciences)
Project Title: Identification of mechanisms of acquired resistance towards BCL-2 inhibitors and strategies to overcome this resistance in B cell lymphoma
Supervisor: Dr. Lukas Frenzel - CECAD Research Center
Voggel, Jenny (M.Sc. In Molecular Nutritional Science)
Project Title: Early nutritional reprogramming with docosahexaenoic acid and choline in IUGR rats to prevent kidney damage in later life by arterial hypertension, RAAS dysregulation, or an aggravated course of inflammatory glomerular disease
Supervisor: Dr. Kai-Dietrich Nuesken - Department of Pediatrics
Wang, Jie (M.Sc.Molecular Cell Biology)
Project Title: The role of the lysine-specific demethylase 1 in the development of hepatocellular carcinoma
Supervisor: Prof. Dr. Margarete Odenthal - Institute for Pathology
Wang, Lingyu (Medicine Doctor Degree - Peking University Health Science Center)
Project Title: The Epigeneitic Crosstalk modifications by the histone demethylase LSD1 in hepatic stellate cells contribute to liver fibrosis
Supervisor: Prof. Dr. Margarete Odenthal - Institute for Pathology
Yan, Shuaifeng (M.Sc. in Medicine)
Project Title: Membrane-bound IL-6R is upregulated on Th17 cells and inhibits Treg cell migration in autoimmune Arthritis
Supervisor: PD Dr. David Kofler - Clinic I for Internal Medicine
Yang, Tsun-Po (M.Sc. in Computer Science)
Project Title: Cell type-specific dynamics of DNA replication timing in primary cancer whole-genome sequences
Supervisor: Prof. Dr. Martin Peifer - Department of Translational Genomics
2021
Bayer, Robin (M. Sc. Biomedical Engineering)
Project Title: Development of a novel in-vitro vascular model for determination of physiological and pathophysiological mechanobiology
Supervisor: Prof. Dr. Jürgen Hescheler - Institute for Neurophysiology
Alawbathani, Salem Awadh Omar (M.Sc. in Human Genetics)
Project Title: Identification and functional characterization of novel genes and variants involved in neurogenetic and musculoskeletal disorders in a Yemeni cohort
Supervisor: Prof. Dr. Angelika Noegel - Institute for Biochemistry
Al-Qadhi, Safwan (Diplom-Ingenieur (FH))
Project Title: A Demand-Controlled Application of Deep Brain Stimulation with a Portable Neurostimulator
Supervisor: PD Dr. Christian Hauptmann - Research Center Jülich
Acharya, Aviseka (M. Sc. in Pharmacy)
Project Title: A Comprehensive Study To Decipher The Impact Of Simulated Microgravity On Human Induced Pluripotent Stem Cell-derived Cardiomyocytes
Supervisor: Prof. Dr. Agapios Sachinidis - Institute for Neurophysiology
Vallabhbhai Hirani, Dharmesh (M. Sc. in Biology)
Project Title: Molecular mechanisms and novel therapeutical targets to prevent aberrant lung growth in newborn mice exposed to prolonged hyperoxia
Supervisor: Prof. Dr. Miguel Alejandre Alcazar - Clinic and Polyclinic for Paediatric and Adolescent Medicine
Muke, Ines (M. Sc. in Klinische und Experimentelle Neurowissenschaften)
Project Title: Modulation of tissue specific membrane transporters for prevention of chemotherapy-induced peripheral neuropathy
Supervisor: Prof. Dr. Helmar Lehmann - Clinic for Neurology
Hsin, Chih-hsuan (M. Sc. FOKUS Pharmazie)
Project Title: Methods to quantify activities of clinically relevant membrane transporters in vitro and in vivo
Supervisor: Prof. Dr. Uwe Fuhr - Institute for Pharmacology
Refaian, Nasrin (M. Sc. in Biology)
Project Title: Influence of Melanoma Cells and Cancer-associated Fibroblasts on (Lymph-)angiogenesis in Conjunctival Melanoma
Supervisor: Prof. Dr. Ludwig Heindl - Department of Ophthalmology
Hassenrück, Floyd (M. Sc. Biomedical Sciences)
Project Title: Profiling PI3K inhibitors with isogenic p110δ-dependent cells: impact of the binding pocket mutation I777M
Supervisor: Dr. Günter Krause - Clinic I for Internal Medicine
Borde, Julika Charlotte Antonia (M. Sc. Biomedical Sciences)
Project Title: Improved breast cancer risk prediction by the implementation of new risk genes and polygenic risk scores
Supervisor: PD Dr. Eric Hahnen - Center for Familial Breast and Ovarian Cancer
Wieters, Frederique Pascal (M. Sc. in Molecular Cell Biology)
Project Title: Evaluation of spasticity in experimental models of ischemic stroke
Supervisor: Dr. Markus Aswendt - Clinic for Neurology
2020
Goranci-Buzhala, Gladiola (M.Sc. in Biological Sciences)
Project Title: Characterization of primary cilia in patient-derived glioma stem cells
Supervisor: Prof. Dr. Jay Gopalakrishnan - Institute for Human Genetics, Heinrich-Heine-University - Dusseldorf
Khayyat, Arwa Ishaq A (M.Sc. in Biochemistry)
Project Title: Genomic and molecular investigations of a large Pakistani family manifesting syndromic intellectual disability associated with microcephaly
Supervisor: Prof. Dr. Angelika Noegel - Institute for Biochemistry
Weber-Lassalle, Nana-Maureen (M.Sc. In Human Biology)
Project Title: Identification of novel breast and ovarian cancer susceptibility genes by hypothesis-driven and exome-wide approaches
Supervisor: PD Dr. Eric Hahnen - Center for Familial Breast- and Ovarian Cancer
Kretschmer, Tobias(M. Sc. in Biomedical Sciences)
Project Title: Maternal High Fat Nutrition is Associated with Placental Dysfunction: Insight in Pathophysiology and Potential Mechanisms
Supervisor: Prof. Dr. Jörg Dötsch - Clinic and Polyclinic for Pediatric and Adolescent Medicine
Meyer, Anja (M. Sc. in Biologie)
Project Title: Interleukin-6 receptor inhibition restores the kinase activity signature of CD4+ T cells and promotes migration of regulatory T cells in rheumatoid arthritis
Supervisor: PD Dr. David Kofler - Clinic I for Internal Medicine
Taiwo, Moyinoluwa Temitope (M. Sc. in Pharmacology and Biotechnology)
Project Title: Role of Platelet-Derived Growth Factor Receptor signalling in microglia-mediated neuroinflammation
Supervisor: Prof. Dr. Thomas Langmann - Department of General Ophthalmology
Schommers, Philipp Frederik (Dr. med.)
Project Title: Restriction of HIV-1 Escape by a Novel Highly Broad and Potent Neutralizing Antibody
Supervisor: Prof. Dr. Florian Klein- Institute for Virology
Hauser, Christoph (Apotheker)
Project Title: Neue Assays zur Charakterisierung der Transamidaseaktivität und der GTP-Bindungsfunktion der Transglutaminase 2
Supervisor: Prof. Dr. Stefan Herzig - Institute for Pharmacology
2019
de Castro Kroner, Juliana (M.Sc. in Biological Sciences)
Project Title: Glucocorticoid regulation of human Th17 responses
Supervisor: Prof. Dr. Mario Fabri - Department for Dermatology and Venerology
Golumba-Nagy, Viktória (Dipl. Biol.)
Project Title: CAR modified T cells resist TGF-b mediated repression through engineered IL-7 triggered IL-2 signaling
Supervisor: Prof. Dr. Hinrich Abken - Department I for Internal Medicine
Hönig, Merle Christine (M.Sc. in Cognitive and Clinical Neuroscience)
Project Title: The Spatial Evolution of Tau Pathology in Alzheimer’s Disease: Influence of Functional Connectivity and Education
Supervisor: Prof. Dr. Alexander Drzezga - Department for Nuclear Medicine
Hos, Nina Judith(Dr. med.)
Project Title: The Role of Type I Interferon in Regulating Macrophage Responses to Salmonella Typhimurium Infection
Supervisor: Dr. Nirmal Robinson - Institute for Medical Microbiology, Immunology und Hygiene
Kiesewetter, Anne (M.Sc. in Biologie)
Project Title: Macrophage function in corneal hem- and lymphangiogenesis
Supervisor: Prof. Dr. Sabine Eming - Department for Dermatology and Venerology
Kimoloi, Sammy Kipchumba (M. Sc. In Clinical Pharmacology)
Project Title: Role of skeletal muscle cells-specific mitochondrial DNA deletions in the development of aging sarcopenia
Supervisor: Prof. Dr. Rudolf Wiesner - Institute for Vegetative Physiology
Le, Viet Nhat Hung (Resident in Ophthalmology)
Project Title: Antilymphangiogenic therapies to promote high-risk corneal graft survival
Supervisor: Prof. Dr. Claus Cursiefen- Department of General Ophthalmology
Mohr, Jasmine (M.Sc. Human- und Molekularbiologie)
Project Title: Molecular mechanisms regulating organ development in neonatal hyperoxia-induced injury
Supervisor: Prof. Dr. Miguel Alejandre Alcazar - Department for Paediatric and Adolescent Medicine
Oberbeck, Sebastian Tobias Karl-Heinz (M.Sc. in Biological Sciences)
Project Title: The T-cell receptor and it’s signaling in T-cell Prolymphocytic Leukemia
Supervisor: PD Dr. Marco Herling - Department I for Internal Medicine
Probst, Kristina (M.Sc. in Biological Sciences)
Project Title: Die Bedeutung der mitochondrialen Atmung für die enchondrale Ossifikation
Supervisor: Prof. Dr. Bent Brachvogel - Department for Paediatric and Adolescent Medicine
Rehorst, Wiebke Adele (M. Sc. in Biological Sciences)
Project Title: Muscle-Secreted Factors in Spinal Muscular Atrophy: CTRP3 at the Interface of Muscle and Neuron
Supervisor: Dr. Min Jeong Kye - Institute of Human Genetics
2018
Baudis, Birte Caren (Dipl. Biol.)
Project Title: Immunological Properties of Embryonic Stem Cell-Derived Cardiomyocytes
Supervisor: PD Dr. Dr. T. Šaric - Institute for Neurophysiology
Chatzigiagkos, Antonis (Dipl. Vet. Med.)
Project Title: The role of macrophage death in atherosclerosis
Supervisor: Prof. Dr. M. Pasparakis - Institute for Genetics / CECAD
Dannhausen, Katharina (M.Sc. in Biology)
Project Title: Retinal degeneration and immunomodulation in juvenile Neuronal Ceroid Lipofuscinoses (jNCL) mice
Supervisor: Prof. Dr. Th. Langmann - Department of Experimental Immunology of the Eye
El-Awaad, Ehab (M.Sc.)
Project Title: Characterization of the direct interaction between the extracellular matrix protein thrombospondin-4 and the gabapentin receptor α2δ-1
Supervisor: Prof. Dr. S. Herzig - Institute of Pharmacology
Gooi, Li Ming (M. Sc. in Biotechnology)
Project Title: Centrosomal Sas-6 in regulation of stem cells and aging
Supervisor: Dr. Jay Gopalakrishnan - CMMC
Hou, Yanhong (M. Sc. in Ophthalmology)
Project Title: Photodynamic therapy and crosslinking treatment of pathologic corneal hemangiogenesis and lymphangiogenesis in ocular surface diseases
Supervisor: Prof. Dr. C. Cursiefen - Department of General Ophthalmology
Nemade, Harshal (M.Sc. in Biochemistry)
Project Title: Evaluation of Etoposide-induced Cardiotoxicity Using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes
Supervisor: Prof. Dr. A. Sachinidis - Institute for Neurophysiology
Philipp, Denise (M.Sc. in Biology)
Project Title: Role of macrophage polarization for MSC-dependent amelioration of hypertrophy in iPS-derived cardiomyocytes
Supervisor:Prof. Dr. Y.-H. Choi - Department for Cardiac and Thoracic Surgery
Rüger, Maria Adele (Dr. med.)
Project Title: Bildgebend-gesteuerte Gentherapie maligner Gliome
Supervisor: Prof. Dr. A. H. Jacobs - European Institute for Molecular Imaging (EIMI)
Schmitt, Anna Katharina (M.Sc. in Biomedical Sciences)
Project Title: Targeting a defective DNA damage response in KRAS-mutant adenocarcinomas
Supervisor: Prof. Dr. C. Reinhardt - Institute for Neurophysiology / CECAD
Telugu, Narasimha Swamy (M.Sc. in Animal Biotechnology)
Project Title: miRNA-503/322 cluster regulates splicing of Ccne1 gene by modulating the expression of a serine and arginine rich splicing factor 1 (SRSF1) to promote cardiomyocyte quiescence
Supervisor: PD Dr. Dr. T. Šaric - Institute for Neurophysiology
2017
Dalvi, Priya (M.Sc. in Bioscience Technolog)
Topic: Molecular mechanisms involved in lysine-specific demethylase 1 mediated oncogenic stress
Supervisor: Prof. Dr. M. Odenthal - Institute for Pathology and CMMC
Huber, Anke (Dipl.-Biol.)
Topic: Novel universal targeting platform to improve AAV's use in gene therapy
Supervisor: Prof. Dr. H. Büning - Hannover Medical School, previous: Department I of Internal Medicine and CMMC
Imhof, Thomas (M.Sc. in Life Sciences, Dr. med. dent.)
Topic: Einfluss von Tenascin-N auf die Regulation und Differenzierung von mesenchymalen Stammzellen in vivo
Supervisor: Prof. Dr. Manuel Koch- Institute for Oral and Musculoskeletal Biology
Krämer, Andrea (M.Sc. in Biomedical Sciences)
Topic: The prognostic and therapeutic relevance of TERT activation in neuroblastoma
Supervisor: Prof. Dr. M. Fischer - Department of Pediatric Oncology and Hematology and CMMC
Macheleidt, Iris Felicitas (M.Sc. in Biotechnology)
Topic: Inhibition of LSD1 in non-small cell lung cancer - in vitro and in vivo
Supervisor: Prof Dr. M. Odenthal - Institute for Pathologyand CMMC
Meumann, Nadja (M.Sc.)
Topic: Induction of a specific immune response and inhibition of tumor angiogenesis in HCC bytumor-associated-antigen-conditioneddecentric cells and adeno-associated virus vectors
Supervisor: Prof. Dr. Hildegard Büning- Hannover Medical School, previous: Department I of Internal Medicine and CMMC
Mikhael, Nelly(M.Sc. in Clinical and Chemical Pathology)
Topic: Novel role for cardiomyocytes in extracellular matrix production: deciphering the fibrotic mechanism
Supervisor:Dr. Kurt Pfannkuche - Institute for Neurophysiology
Moosa, Shahida (MMed, FCMG)
Topic: Next-Generation-Sequencing in the Clinic: novel genes and novel mutations resolve the diagnostic odyssey for patients with undiagnosed genetic disorders
Supervisor: Prof. Dr. B. Wollnik - Institute of Human Genetics, Unversity of Göttingen, previous: Institute for Human Genetics, University of Cologne and CMMC
Neumann, Lars (M.Sc.)
Topic: Functional role of PI3K-Delta in malignant B cells
Supervisor: Dr. Günter Krause - Department of Internal Medicine
Schöllhorn, Laura (Dipl.-Biol.)
Topic: Corneal lymphangiogenesis is necessary to induce autoimmune dry eye disease
Supervisor: Prof. Dr. Claus Cursiefen - Deptartment of Ophthalmology and CMMC
Vondey, Verena (M.Sc. in Biochemistry)
Topic: LYN-dependent intrinsic functions of malignant B cells
Supervisor:Prof. Dr. G. Krause - Department I of Internal Medicine
Yu, Xiaojie (M. Sc. in Biochemistry and Molecular Biology)
Topic: Overexpressed microRNA-198 is secreted via exosomes from hepatoma cells
Supervisor: Prof. Dr. Margarete Odenthal- Institute for Pathology and CMMC
Zare Mehrjardi, Nagres (M.Sc. in Medical Immunology)
Topic: Duplication of chromosome 1q in zinc finger nuclease edited human induced pluripotent stem cell-derived neural stem cells results in their higher proliferation rate in vitro and in vivo
Supervisor: PD Dr. T. Šaric - Institute for Neurophysiology
2016
Abhijeet, Joshi (M.Sc.)
Topic: Extrinsic modulation of regenerative pathways differentially affects axonal recovery in pre-clinical models of peripheral nerve disorders
Supervisor: PD Dr. Helmar Lehmann - Department of Neurology
Amer, Wafa (M.Sc.)
IPMM Thesis:Comprehensive analysis of disease related nuclear and mitochondrial genes in hepatocellular carcinoma
Supervisor: Prof. Dr. Margarethe Odenthal - Institute for Pathology
Bobylev, Ilja (Dipl. Biol.)
Topic: The role of mitochondria in the pathogenesis of chemotherapy-induced peripheral neuropathy
Supervisor: PD Dr. Helmar Lehmann - Department of Neurology
Deshmukh, Jayesh (M.Sc.)
Topic: Epidermal RAC 1 regulates the DNA damage response and protects from UV-light induced skin carcinogenesis and keratinocyte apoptosis
Supervisor: Prof. Ingo Haase / Dr. Sandra Iden - Department of Dermatology / CECAD Cologne
Academic Grade: Dr. nat. med.
Dietlein, Felix (Dr. rer. nat. / Dr. med. cand.)
Topic: A framework to comprehensively identify synergistic drug interactions in cancer
Supervisor: Prof. Dr. Christian Reinhardt - Department I of Internal Medicine
Academic Grade: Dr. nat. med.
Faitschuk, Elena (Dipl. Chem.)
Topic: A novel dual chain-based design of a Chimeric Antigen Receptor (CAR) for Adoptive cell therapy and an FcµR-specific CAR for improved targeting of Chronic Lymphocytic Leukemia (CLL)
Supervisor: Prof. Dr. Hinrich Abken - Department I of Internal Medicine
Göckeritz, Elisa (M.Sc. - Clinical Molecular Science)
Thesis: Exploring oncogenic functions of malignant B cells by inhibition of PI3K and BTK
Supervisor: Dr. Günter Krause - Department I for Internal Medicine
Hos, Deniz (Dr. med.)
IPMM Thesis: The Contribution of Macrophages to Inflammatory Corneal lymphangiogenesis
Supervisor: Prof. Dr. Claus Cursiefen - Department of Ophthalmology
Martyniszyn, Alexandra (Dipl.-Biol.)
Topic: Duales Targeting von malignen B-Zellen mit einem bispezifischen chimären Antigen-Rezeptor (CAR) zur Erkennung von Antigen-Verlustvarianten
Supervisor: Prof. Dr. Hinrich Abken - Department I of Internal Medicine / CMMC
Meder, Lydia (M.Sc.)
Topic: Deciphering the role of NOTCH, ASCL1, p53 and RB in secondary small cell lung carcinomas
Supervisor: PD Dr. Lukas Heukamp - former member Department I of Internal Medicine
Sheikh, Miriam (Pharmacist)
Topic:Identification and kinetic characterization of novel inhibitors of Cholesterol Esterase and new insights into the bile salt-induced activation mechanism
Supervisor: Prof. Dr. Stefan Herzing - Institute for Pharmacology
Scholz, Rebecca (Dipl.-Oecotroph.)
Topic: Microglia as therapeutic targets in retinal degeneration: role of translocator protein (18 kDa) (TSPO) and minocycline
Supervisor: Prof. Dr. Thomas Langmann - Department of Ophtamology, Lab. of Experimental Immunology of the Eye
Volz, Caroline (M.Sc.)
Topic: The role of VGFR2 and EphA2 in tumor cell invasion in non-small-cell lung cancer
Supervisor: PD Dr. Dr. Roland Ullrich - Department I of Internal Medicine
Zhang, Liang (Dr. med.)
Topic: Capsid-engineering overcomes barriers towards endothelial cell transduction
Supervisor: Prof. Dr. Hildegard Büning - Department I of Internal Medicine / CMMC / present adress: Hannover Medical School
2015
Aslanidis, Alexander (M.Sc.)
Topic: Characterization of photoreceptor gene regulation and modulation of microglial reactivity in the retina
Supervisor: Prof. Dr. Th. Langmann - Department of Experimental Immunology of the Eye
Liu, Yicheng (M.Sc.)
Topic: New insights into the molecular pathogenesis of accelerated aging phenotypes in Hallermann-Streiff and Bloom syndromes
Supervisor: Prof. Dr. Bernd Wollnik - Institute for Human Genetics
Schmied, Sabine (M.Sc.)
Topic: Characterization of tumor-antigen-specific T cells – insights into WT1- and HPV16-specific T cell repertoires
Supervisor: Dr. Anne Richter / Dr. Mario Assenmacher - Milteny Biotec GmbH
2014
Beleggia, Filippo (M.Sc.)
Topic: Innovative strategies for gene identifaction and functional analysisof progeria syndromes
Supervisor: Prof. Dr. Bernd Wollnik - Institute for Human Genetics
Bohlen, Susanne (M.Sc.)
Topic: NADPH-oxidase derived reactive oxygen species (ROS) regulateStaphylococcus aureus-induced autophagy through PI3K
Supervisor: Dr. Oleg Krut - Institute for Med. Microbiology, Immunology and Hygiene
Chatterjee, Sampurna (M.Sc.)
Topic: VEGFR2 as a biomarker and therapeutic target in non small cell lung cancer
Supervisor: PD Dr. med. Dr. nat. med. Roland Ullrich - Department I of Internal Medicine
Dibué-Adjei, Maxine (M.Sc.)
Topic: Mechanisms of the Cav2.3 Calcium Channel’s Role in Epileptogenesis and Antiepileptic Pharmacotherapy
Supervisor: Prof. Dr. T. Schneider - Institute for Neurophysiology
Lehmann, Martin (Dipl.-Biol.)
Topic: A novel model system to study the role of catecholamines in cardiac lineage commitment of embryonic stem cells and functional response to proarrhytmic drugs
Supervisor: Prof. Dr. Jürgen Hescheler - Institute for Neurophysiology
Lichtenauer, Urs (Dr. med.)
Topic: Regulation of adrenocortical growth and steroidogenesis - stem cells and orphan nuclear receptors
Supervisor: Dr. F. Beuschlein - Department of Medicine, LMU, München
Seidel, Daniela (Dipl.-Biol.)
Topic: Genomic signatures of clinical phenotypes in non-small cell lung cancer
Supervisor: Prof. Dr. R. Thomas - MPI for Neurological Research, Functional Cancer Genomics
Willkomm, Lena (M.Sc.)
Topic: The effects of lactate on skeletal muscle
Supervisor: Prof. Dr. W. Bloch - Deutsche Sporthochschule
2013
Dafinger, Claudia (Dipl.-Biol.)
Topic: Molekulare Pathogenese des Joubert-Syndroms - die Rolle des Proteins KIF7
Supervisor: Prof. Dr. Th. Benzing - Department II of Internal Medicine
Keupp, Katharina (Dipl.-Biol.)
Topic: Novel insights into molecular mechanisms of inherited bone disorders
Supervisor: Prof. Dr. B. Wollnik - Institute for Human Genetics
Kocak, Hayriye (Dipl.-Biol.)
Topic: Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma
Supervisor: PD Dr. M. Fischer - Department of Pediatric Oncology and Hematology
Pohl, Esther (Dipl.-Biol.)
Topic: Molecular pathogenesis of selected autosomal recessively inherited disorders: from gene to function
Supervisor: Prof. Dr. B. Wollnik - Institute for Human Genetics
Sallach, Jessica (M.Sc.)
Topic: Exploiting high-throughput screens to optimize Adeno-Associated viral vectors for gene transfer into primary human kerationcytes
Supervisor: PD Dr. H. Büning - CMMC / Department I of Internal Medicine
Rabenhorst, Anja (Dipl.-Biol.)
Topic: Modulation of tumor microenvironment and anti-tumor immunity by mast cells
Supervisor: PD Dr. K. Hartmann - Department of Dermatology
2012
Alcazár, Miguel (Dr. med.)
Topic: Role of neuropeptide Y in lung development: implications in the pathogenesis of chronic lung disease
Supervisor: Prof. Dr. J. Dötsch - Department of Pediatrics
Brüggemann, Sabrina (Dipl.-Biol.)
Topic: Genomic instability and DNA damage response in premature aging syndromes
Supervisor: PD Dr. M. Stoff-Khalili - Institute for Virology
Esser, Knud (Dipl.-Chem.)
Topic: Das Hepatitis B Virus folgt dem Transport der neutralen Lipide in die Leber und in die Hepatozyten, um seine Wirtszelle zu erreichen und zu infizieren
Supervisor: Prof. Dr. U. Protzer - Institute for Virology Munich (former Inst. for IMMIH Cologne)
Rother, Eva (Dr. med.)
Topic: Neuroendokrine Kontrolle der Gewichtsregulation
Supervisor: Prof. Dr. J. Brüning - Center for Endocrinology, Diabetology and Preventive Medicine / MPI for Neurological Research / CMMC
Wen, Tingting (M.Sc.)
Topic: Regulation of Laminin 332 expression
Supervisor: Prof. Dr. M. Aumailley - Institute for Biochemistry II
2011
Plume, Nadine (Dipl.-Biol.)
Topic: Molekulare Mechnismen isolierter und Syndrom-assoziierter Lipidstoffwechselerkrankungen
Supervisor: Dr. B. Wollnik - CMMC-Junior Research Group V / Institute for Human Genetics
Rybniker, Jan (Dr. med.)
Topic: Identification and characterization of host-shut-off proteins of Mycobacteriophages
Supervisor: PD Dr. P. Hartmann - Department I of Internal Medicine
Séquaris, Gilles (Dipl.-Biol.)
Topic: Molecular mechanism of Indian Hedgehog signalling in human sebocytes
Supervisor: Dr. C. Niemann - CMMC-Junior Research Group IV
Siebolts, Udo (Dr. med Dipl.- Biol.)
Topic: New aspects into pathophysiology and molecular diagnostics of myeloproliferative neoplasms
Supervisor: Prof. Dr. C. Wickenhauser - Institute for Pathology, Univ. of Leipzig (former Institute for Pathology, Univ. of Cologne)
Vierkotten, Sarah (Dipl.-Biol.)
Topic: HTR1: Ein Kandidatengen für die Altersbedingte Makuladegeneration
Supervisor: PD Dr. S. Fauser - Center of Ophthalmology
Weiß, Jonathan (Dipl.-Biol.)
Topic: Deciphering oncogene dependencies and signaling pathway alterations in non small cell lung cancer
Supervisor: Prof. Dr. R. Thomas - MPI for Neurological Research / JRG Functional Cancer Genomics
2010
Ernst, Marianne (M.Sc.)
Topic: Expression of Foxo 1 versions in the mouse
Supervisor: Prof. Dr. Jens Brüning - Institute for Genetics and CMMC
Gonzalez, Nela Klein (Dr. med.)
Topic: Homing and migration of CD40-activated B cells
Supervisor: Dr. Dr. Michael v. Bergwelt-Baildon - Department of Internal Medicine I
Jangsangthong, Wanchana (M.Sc)
Topic: Structural determinants of gating properties of voltage-gated L-type Calcium channels as revealed by single-channel analysis
Supervisor: Prof. Dr. Stefan Herzig - Institute for Pharmacology and CMMC
Pawlik, Barbara (Dipl.-Biol.)
Topic: Molecular mechanisms of congential limb malformations
Supervisor: Dr. Bernd Wollnik - CMMC-Junior Research Group V / Institute for Human Genetics
Petersson, Monika (Dipl.-Biol.)
Topic: Regulation of morphogenesis and tumourigenesis in the skin
Supervisor: Dr. Catherin Niemann - CMMC-Junior Research Group IV
Academic Grade: Dr. rer. nat.
Uhrig, Silke (Dipl.-Biol.)
Topic: Detailed analysis of cell infection by capsid engineered AAV vectors
Supervisor: PD Dr. Hildegard Büning - Department of Internal Medicine I and CMMC
Ullrich, Roland (Dr. med.)
Topic: Molecular imaging for the quantitative assessment of tumor proliferation, progression and the early assessment of molecular targeted treatment response
Supervisor: Prof. Dr. Andreas Jacobs - EIMI, Univ. of Münster (former Dept. of Neurology, Univ. of Cologne)
2009
Elhamine, Fatiha (Dipl.-Biol.)
Topic: Myofibrillar protein expression and contractility in the right ventricle from infants with congenital heart disease associated with right ventricular outflow obstruction
Supervisor: Prof. G. Pfitzer - Institute for Vegetative Physiology and CMMC
Hettich, Moritz (Dipl.-Biol.)
Topic: Role of neuronal IGF-1 receptor signaling for the pathogenesis of Alzheimer´s disease
Supervisor: Prof. Dr. W. Krone - Department of Internal Medicine II
Academic Grade: Dr. rer. nat.
Kopacek, Anke (Dipl.-Biol.)
Topic: Generation, expression and functional analysis of recombinant
bi-specific CD3 x NCAM antibodies for the therapy of patients with rezidative neuroblastoma
Supervisor: Prof. F. Berthold - Dept. of Pediatric Oncology & Hematology and CMMC
Könner, Christine (Dipl.-Biol.)
Topic: Genetic Microdissection of Insulin Action on Neurocircuits in Control of Glucose and Energy Homeostasis
Supervisor: Prof. Dr. Wilhelm Krone - Department of Internal Medicine II and CMMC
Academic Grade: Dr. rer. nat.
Meemboor, Sonja (M.Sc.)
Topic: Streptococcus pneumoniae capsular polysaccharide-mediated CD4+ T cell-dependant abscess formation requires IL-6 and TLR-4
Supervisor: PD Dr. Wiltrud Kalka-Moll - Institute for Medical Microbiology, Immunology and Hygiene
Pütz, Sandra (Dipl.-Biol.)
Topic: Role of caldesmon in the regulation of smooth muscle actomyosin interaction
Supervisor: Prof. Gabriele Pfitzer - Institute for Vegetative Physiology and CMMC
Radhakrishnan, Kayalvizhi (M.Sc.)
Topic: Interaction partners of the E-/R-type voltage gated calcium channels which are involved in the phorbolester mediated stimulation of Cav2.3 calcium channel
Supervisor: Prof. Toni Schneider - Institute for Neurophysiology and CMMC
Academic Grade: Dr. rer. nat.
Schievenbusch, Stephanie (Dipl.-Biol.)
Topic: HGF as a multifunctional and anti-fibrotic-agent with high impact on gene therapy for renal tubulointestitial fibrosis Supervisor Academic Grade 2005
Supervisor: Prof. Dr. Margarete Odenthal - Institute for Pathology
2008
Quasdorff, Maria (Dr. med.)
Topic: Die Bedeutung von Wirtsfaktoren für die Hepatitis B und Hepatitis B Virus-assoziierte hepatozelluläre Karzinome und ihre therapeutische Beeinflussung
Supervisor: Prof. Dr. U. Protzer - Institute for Virology TU Munich
Academic Grade: Dr. nat. med.
Rohmann, Edyta (Dipl.-Biol.)
Topic: Molekulare Pathogenese arrhythmogener Erkrankungen
Supervisor: Dr. Bernd Wollnik - CMMC-Junior Research Group V / Institute for Human Genetics
Academic Grade: Dr. nat. med.
Steingen, Caroline (Dipl.-Biol.)
Topic: The relevance of circulating progenitor cells for the regeneration of dysfunctional endothelium
Supervisor: PD Dr. K. Brixius - Institute for Cardiovascular Research, & Sports Medicine, German Sport University of Cologne
Academic Grade: Dr. rer. nat.
Zedler, Uta (Dipl.-Biol.)
Topic: Fluorescent hepatitis B virus particles. Dendritic cells allow expression of viral antigens but not infection of with hepatitis B virus
Supervisor: Prof. Dr. U. Protzer - Institute for Virology TU Munich
2007
Meyer, Philipp T. (Dr. med.)
Topic: In vivo Quantification of Cerebral A1-Adenosin-Rezeptoren mittels [18F]CPFPX und der Positronen-Emissions-Tomographie: Quantifizierungsmodelle und erste Untersuchungen physiologischer und pathologischer Prozesse
Supervisor: Prof. K. Zilles - Institute for Nuclear Chemistry (INC) Research Center Jülich
Miletic, Hrvoje (Dr. med.)
Topic: Gene therapy of malignant glioma with lentiviral vectors
Supervisor: Prof. M. Deckert - Department of Neuropathology
Schnaith, Annabelle (Pharmazy)
Topic: Identification and characterization of cytotxic factors produced by Staphylococcus aureus
Supervisor: Prof. M. Krönke - Institute for Medical Microbiology, Immunology & Hygiene and CMMC
Song, Jian (M.Sc.)
Topic: The role of the cytoplasmatic tail of IgG1 B cell receptors in signalling and B cell development
Supervisor: Prof. A. Waisman - I. Medical Department and Polyclinic, University of Mainz (former Institute for Genetics, University of Cologne)
2006
Nussbaum, Tanja (Dipl.-Biol.)
Topic: Funktionelle Aspekte der IGF-II Inhibierung im humanen hepatozellulären Karzinom unter Berücksichtigung möglicher therapeutischer Ansätze
Supervisor: Prof. P. Schirmacher - Institute for Pathology, Univ. of Heidelberg (former Institute for Pathology, Univ. of Cologne)
Academic Grade: Dr. rer. nat.
Weiergräber, Marco (Dr. med.)
Topic: Funktionelle Charakterisierung des neuronalen E-Typ Ca2+-Kanals im kardio-vaskulären System der Maus
Supervisor: Prof. T. Schneider - Institute for Neurophysiology and CMMC
2005
Schnickmann, Stephanie (Dipl.-Biol.)
Topic: Bedeutung des HGF-MET Signalsystems im Rahmen der epidermalen Wundheilung
Supervisor: Prof. P. Schirmacher - Institute for Pathology, Univ. of Heidelberg (former Institute for Pathology, Univ. of Cologne)
Academic Grade: Dr. rer. nat.