Hammerschmidt, Matthias - C 06

Novel pathomechanisms of spine abnormalities and intervertebral disc degeneration caused by mutations in the fatty acid synthase gene

Prof. Dr. Matthias Hammerschmidt
Prof. Dr. Matthias Hammerschmidt

Institute of Zoology - Biocenter Cologne

CMMC - PI - C 06
Executive Board Member

Institute of Zoology - Biocenter Cologne

Zülpicher Str. 47b

50674 Cologne

Introduction

For information about Prof. Hammerschmidt's research and work, please visit the following page: AG Hammerschmidt

2024 (up to June)
  • Asif M, Khayyat AIA, Alawbathani S, Abdullah U, Sanner A, Georgomanolis T, Haasters J, Becker K, Budde B, Becker C, Thiele H, Baig SM, Isidoro-Garcia M, Winter D, Pogoda HM, Muhammad S, Hammerschmidt M, Kraft F, Kurth I, Martin HG, Wagner M, Nurnberg P, and Hussain MS (2024). Biallelic loss-of-function variants of ZFTRAF1 cause neurodevelopmental disorder with microcephaly and hypotonia. Genet Med26, 101143. doi:10.1016/j.gim.2024.101143.
     
  • Benard EL, Kucukaylak I, Hatzold J, Berendes KUW, Carney TJ, Beleggia F, and Hammerschmidt M (2024). wnt10a is required for zebrafish median fin fold maintenance and adult unpaired fin metamorphosis. Dev Dyn253, 566-592. doi:10.1002/dvdy.672.
     
  • Raote I, Rosendahl AH, Hakkinen HM, Vibe C, Kucukaylak I, Sawant M, Keufgens L, Frommelt P, Halwas K, Broadbent K, Cunquero M, Castro G, Villemeur M, Nuchel J, Bornikoel A, Dam B, Zirmire RK, Kiran R, Carolis C, Andilla J, Loza-Alvarez P, Ruprecht V, Jamora C, Campelo F, Kruger M, Hammerschmidt M, Eckes B, Neundorf I, Krieg T, and Malhotra V (2024). TANGO1 inhibitors reduce collagen secretion and limit tissue scarring. Nat Commun15, 3302. doi:10.1038/s41467-024-47004-1.
2023
  • Benard EL, Kucukaylak I, Hatzold J, Berendes KUW, Carney TJ, Beleggia F, and Hammerschmidt M (2023). wnt10a is required for zebrafish median fin fold maintenance and adult unpaired fin metamorphosis. Dev Dyn. doi:10.1002/dvdy.672.
     
  • Hatzold J, Nett V, Brantsch S, Zhang JL, Armistead J, Wessendorf H, Stephens R, Humbert PO, Iden S, and Hammerschmidt M (2023). Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects. PLoS Genet 19, e1010873. doi:10.1371/journal.pgen.1010873.
     
  • Pogoda HM, Riedl-Quinkertz I, and Hammerschmidt M (2023). Direct BMP signaling to chordoblasts is required for the initiation of segmented notochord sheath mineralization in zebrafish vertebral column development. Front Endocrinol (Lausanne) 14, 1107339. doi:10.3389/fendo.2023.1107339.