Individual Project Funding Program
Research Area A
Mechanisms of tumor development: intrinsic and extrinsic control of cell proliferation and tissue invasion
- Fischer, Matthias - A 01
Tracing Determinants of Malignant Transformation in Neuroblastic Tumors on the Single Cell Level - Frezza, Christian | Schatton, Désirée - A 02
Dietary Interventions for Renal Cancer in Hereditary Leiomyomatosis and Renal Cell Carcinoma - Hillmer, Axel | Büttner, Reinhard - A 03
Developing New Treatment Concepts for "KEAP1"-Mutated Lung Adenocarcinoma - Jachimowicz, Ron D. - A 04
Targeting UBQLN1-Driven Oncogenesis in Lung Adenocarcinoma - von Karstedt, Silvia - A 05
Modelling KRAS Inhibitor Resistance Driven by Acquired KRAS Mutations in Pancreatic Cancer - Motori, Elisa | Kreuzaler, Peter - A 06 (TP)
Neuro-Metabolic Priming in Breast Cancer: Uncovering Innervation-Induced Mechanisms of Brain Metastatic Competence - Walczak, Henning - A 07
Evaluation of Novel Pro-Apoptotic Combination Therapies to Overcome Therapy Resistance in Haematological Malignancies
Research Area B
Principles of immunity, inflammation and infection
- Brinkkötter, Paul | Brähler, Sebastian - B 01
Plexin Signaling in Podocyte Disease – Linking Inflammation and Actin Cytoskeleton Remodeling - Kashkar, Hamid - B 02
Role of IAPs in Gastrointestinal Inflammatory Diseases and Therapeutic Interventions - Klein, Florian | Rohde, Malena - B 03
HIV-1 Post-Treatment Control by Autologous Neutralizing Antibodies - Liccardi, Gianmaria - B 04
The Role of Necroptosis in the Pathogenesis and Treatment of STING Associated Vasculopathy with Onset in Infancy (SAVI) - Mathur, Sanjay | Hallek, Michael - B 05 (TP)
Stimuli-responsive Nanocarriers for Precision Drug Delivery and Tumor Microenvironment - Neumann-Haefelin, Christoph | Meli-Lang, Julia - B 06
Impact of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) on Immune Control of Chronic Hepatitis B Virus Infection - Pasparakis, Manolis - B 07
Role of Cell Death in Regulating the cGAS-STING-Dependent Interferonopathy Caused by TREX1 Deficiency - Rybniker, Jan | Theobald, Sebastian - B 08
Comparative Analysis of Cross-Protective Trained Innate Immunity Induced by Different Vaccine Platforms - Schlößer, Hans A - B 09
Elucidating IFN-γ-related Immune Escape as Mechanism of Resistance to Immunotherapy in Human Gastric Cancer and Orthotopic Mouse Models of Genomically Stable and Chromosomally Instable Gastric Adenocarcinoma - Schommers, Philipp - B 10
Engineering Novel Multi-Specific HIV Antibodies to Overcome Viral Resistance - Zehner, Matthias - B 11
Investigation of HCMV Resistance and Immune Escape Pathways – HCMV-RISE
Research Area C
Molecular mechanisms and metabolic control of tissue degeneration and regeneration
- Benzing, Thomas | Gather, Malte - C 01 (TP)
Biophysics of Podocyte Machanoregulation and Contractility - Bergami, Matteo - C 02
Mechanisms Underlying Epileptic Phenotypes by the Mitochondrial Transport Adaptor Protein TRAK1 - Brachvogel, Bent - C 03
Reductive Imbalances as Driver of Cartilage Degeneration in Aging and Mitochondrial Disease - Cabreiro, Filipe | Struble, Sebastian | Solagna, Francesca - C 04
Role of the Gut Microbiota in Polycystic Kidney Disease - Eming, Sabine | Reznick, Jane - C 05 (TP)
Investigating Molecular Mechanisms Controlling Regenerative Plasticity and Scar-free Healing in Mammals - Gatto, Graziana - C 06
Unlocking the Prodromal Code: Early Signs of Sensory Dysfunctions in Diabetic Neuropathy - Hammerschmidt, Matthias - C 07
Analysis of the Molecular Mechanisms Underlying Scar-free Healing of Cutaneous Wounds in the Zebrafish - Isbrandt, Dirk | Tsortouktzidis, Despina - C 08
Precision Therapies for HCN1-DEE - Korotkova, Tatiana - C 09
Neuronal Mechanisms of Hunger Resistance: Functional Roles of Cholecystokinin (CCK)-expressing Lateral Hypothalamic Neurons in Obesity and Anorexia Nervosa - Rugarli, Elena I - C 10
The Role of the Integrated Stress Response and of Paraplegin-specific Substrates in Neurodegeneration Caused by Mutations in SPG7 - Schermer, Bernhard | Ebert, Lena - C 11
Next-Generation Cilia Proximity Labeling to Decipher the Pathomechanisms of Human Ciliopathies - Schwarz, Günter | Köhler, Felix - C 12
MBK2910 to Treat Acute Kidney Injury: From Molecular Mechanism to Clinical Application - Trifunovic, Aleksandra | Riemer, Jan - C 13 (TP)
Turning Over Complex I: A Redox-Guided Route to Mitochondrial Resilience in Metabolic Disease - Vilchez, David - C 14
Defining Cold-induced Pathways to Prevent Aging and Age-related Diseases - Vogt, Johannes | Kepser, Lara-Jane | Endle, Heiko - C 15
Lipid Signaling in the Regulation of Circuit Integration and Cell Death During Adult Neurogenesis
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