
March 12, 2025 - Program
9.00 - 10.30 a.m.
Meeting of the CMMC Executive Board
(only for members of the EC Board)
Location: Seminar Room, MTI-Lecture Hall (Venue of the CMMC Annual Retreat)
10.00 - 10.50 a.m.
Reception with Registration
For Poster Presenters: please collect your poster board number and display your poster on the designated board
11.00 - 11.15 a.m.
Welcome Address - CMMC Annual Retreat 2025
Esther von Stebut-Borschitz - Vice Dean of Science - Translation - Transfer, Faculty of Medicine
Stanislav Kopriva - Vice Dean of Research, Faculty of Mathematics and Natural Sciences
Thomas Benzing - Chair of the CMMC
Introduction to the scientific program by the organizers
Alessandro Annibaldi • Johannes Brägelmann • Sebastian Brähler • Elisa Motori • Débora Trentini Schmidt
11.15 - 12.45 p.m.
Short Talk Session I - CMMC Research Area C
Molecular mechanisms and metabolic control of tissue degeneration and regeneration
Chairs: Elisa Motori and Débora Trentini Schmidt
11.15 - 11.30 a.m.
Consequences of age-related G-quadruplex formation for the fidelity of mammalian transcription
Robert Hänsel-Hertsch1andAndreas Beyer2
CMMC1 and CECAD2
11.30 - 11.45 a.m.
Cellular and molecular crosstalk in skin wound resolution
Sabine Eming and Mario Fabri
Dept. of Dermatology and Venereology
11.45 - 12.00 p.m.
Understanding the role of nonsense-mediated mRNA decay in differentiation, development and disease
Niels Gehring
Institute for Genetics, Dept. of Biology
12.00 - 12.15 p.m.
The quality control Ubiquitin ligase CHIP: a key regulator of Insulin signaling, healthy aging & neuroprotection
Thorsten Hoppe
Institute for Genetics and CECAD
12.15 - 12.30 p.m.
Skin insulin-IGF signalling in health and disease
Carien Niessen
Dept. of Cell Biology of the Skin and CECAD
12.30 - 12.45 p.m.
Two are not enough: Extra base pairs in nucleic acids and their application (Research Area A)
Stephanie Kath-Schorr
Institute of Organic Chemistry (MNF)
12.45 - 2.00 p.m.
Lunch Break and Industrial Exhibition
2.00 - 3.15 p.m.
Flash Talk Session I and CMMC Info I
Chairs: Débora Trentini Schmidt and Alessandro Annibaldi
- P 01 - P xx: Flash Talk Presentations of Posters with odd Numbers
- CMMC Info: CMMC New Gene - Empowering CMMC Junior Faculty - GAMMA - CMMC´s Sustainability Approach
3.15 - 5.00 p.m.
Poster Session I and Industrial Exhibition
with Coffee and Cake
5.00 - 5.45 p.m.
CMMC Lecture I
Understanding the metabolic cross-talk between cancer and immune cells in metastatic melanoma
Ilaria Elia, Dept. of Cellular and Molecular Medicine, KU Leuven, Leuven, BE
Chair: Elisa Motori
at 5.45 p.m.
CMMC Get-Together at the venue and Industrial Exhibition
March 13, 2025 - Program
9.00 - 10.45 a.m.
Short Talk Session II - CMMC Research Areas B
Principles of immunity, inflammation and infection
Chairs: Johannes Brägelmann and Christina Ising
9.00 - 9.15 a.m.
The hidden cost of hosting a microbiome
Filipe Cabreiro, Mauro Corrado and Francesca Solagna
CECAD
9.15 - 9.30 a.m.
Cell death and immunity
Hamid Kashkar
Institute for Molecular Immunology
9.30 - 9.45 a.m.
Antibodies and the challenge of viral diversity
Florian Klein
Institute of Virology
9.45 - 10.00 a.m.
Deciphering innate immune responses in SARS-CoV-2 infection and vaccination
Sebastian Theobald and Jan Rybniker
Dept. I of Internal Medicine
10.00 - 10.15 a.m.
Heme biogenesis flux regulates switch between inflammation and ferroptosis
Aleksandra Trifunovic
Institute for Mitochondrial Diseases and Ageing and CECAD
10.15 - 10.45 a.m.
CMMC Report
incl. announcement “submission of project proposals – 11th CMMC Funding Period” and introduction of Central Core Facilities (MF) presented by Marten Schulte (CCF-Coordinator)
Thomas Benzing - Chair of the CMMC
10.45 - 11.00 a.m.
Coffee Break and Industrial Exhibition
11.00 - 11.45 a.m.
CMMC Lecture II
Patient-level multiomics analysis of human heart and kidney disease
Christoph Kuppe, Department of Nephrology, RWTH Aachen, Aachen, DE
Chair: Sebastian Brähler
11.45 - 12.45 p.m.
Flash Talk Session II and CMMC Info II
Chairs: Alessandro Annibaldi and Débora Trentini Schmidt
- P 02 - P xx: Flash Talks of Poster Presenters with even Numbers
- CMMC Info II: Flow Cytometrie (M. Albert) – CyTOF/Hyperion (P. Hofmann) - CMMC/CECAD-Microscopy (M. Babaki)
12.45 - 1.15 p.m.
Lunch Break and Industrial Exhibition
1.00 - 2.45 p.m.
Poster Session II and Industrial Exhibition
2.45 - 3.45 p.m.
Short Talk Session III - CMMC Research Area A
Mechanisms of tumor development: intrinsic and extrinsic control of cell proliferation and tissue invasion
Chairs: Sebastian Brähler and Roland Ullrich
2.45 - 3.00 p.m.
Role of synaptic hijacking in SCLC brain metastatic growth
ElisaMotori1and Matteo Bergami2
CMMC1 and CECAD2
3.00 - 3.15 p.m.
Ubiquilins expose an actionable target in cancer therapy
Ron Jachimowicz
Dept. I of Internal Medicine and MPI of Ageing
3.15 - 3.30 p.m.
Mechanisms of Hedgehog-Gli signaling in mammalian skin
Catherin Niemann
CMMC and Institute for Biochemistry (MF)
3.30 - 3.45 p.m.
Essential role of macrophage-derived LYN tyrosine kinase in tumor support
Phuong-Hien Nguyen1, Renata Stripecke1 and Alessandro Annibaldi2
Dept. I for Internal Medicine1 and CMMC2