Trifunovic, Aleksandra - B 11
Role of mitochondria in the regulation of innate immunity responses
Prof. Dr. Aleksandra Trifunovic
Inst. for Mitochondrial Diseases and Ageing | CECAD Research Center
CMMC - PI - B 11
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Inst. for Mitochondrial Diseases and Ageing | CECAD Research Center
Joseph-Stelzmann-Str. 26
50931 Cologne
Introduction
For information about Prof. Trifunovic's research and work, please visit the following page: Trifunovic Lab
Affiliations
- CECAD: https://www.cecad.uni-koeln.de/research/principal-investigators/prof-dr-aleksandra-trifunovic
- CRC 1218: https://sfb1218.uni-koeln.de/projects/research-area-b-mitochondria-in-stress-response-and-disease/b01-trifunovic
- GRK 2047: https://kardiologie.uk-koeln.de/forschung/dfg-funded-ccrc-graduate-program/projects/
Publications generated during 1/2023-12/2025 with CMMC affiliation
2024 (up to June)
- Moschandrea C, Kondylis V, Evangelakos I, Herholz M, Schneider F, Schmidt C, Yang M, Ehret S, Heine M, Jaeckstein MY, Szczepanowska K, Schwarzer R, Baumann L, Bock T, Nikitopoulou E, Brodesser S, Kruger M, Frezza C, Heeren J, Trifunovic A, and Pasparakis M (2024). Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes. Nature625, 385-392. doi:10.1038/s41586-023-06857-0.
2023
- Montoro-Gamez C, Nolte H, Molinie T, Evangelista G, Troder SE, Barth E, Popovic M, Trifunovic A, Zevnik B, Langer T, and Rugarli EI (2023). SARM1 deletion delays cerebellar but not spinal cord degeneration in an enhanced mouse model of SPG7 deficiency. Brain 146, 4117-4131. doi:10.1093/brain/awad136.
- Peker E, Weiss K, Song J, Zarges C, Gerlich S, Boehm V, Trifunovic A, Langer T, Gehring NH, Becker T, and Riemer J (2023). A two-step mitochondrial import pathway couples the disulfide relay with matrix complex I biogenesis. J Cell Biol 222. doi:10.1083/jcb.202210019.
- Rozsivalova DH, Popovic M, Kaul H, and Trifunovic A (2023). Isolation of Functional Mitochondria and Pure mtDNA from Murine Tissues. Methods Mol Biol 2615, 3-16. doi:10.1007/978-1-0716-2922-2_1.
- Spath MR, Hoyer-Allo KJR, Seufert L, Hohne M, Lucas C, Bock T, Isermann L, Brodesser S, Lackmann JW, Kiefer K, Koehler FC, Bohl K, Ignarski M, Schiller P, Johnsen M, Kubacki T, Grundmann F, Benzing T, Trifunovic A, Kruger M, Schermer B, Burst V, and Muller RU (2023). Organ Protection by Caloric Restriction Depends on Activation of the De Novo NAD+ Synthesis Pathway. J Am Soc Nephrol 34, 772-792. doi:10.1681/ASN.0000000000000087.