Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Inducing mtDNA deletions in mouse tissues to study if and how they affect ageing
Rudi Wiesner
Dept. of Physiology, Univ. of Cologne
RESI Seminar Series
4.00 p.m. – Seminar Room, CMMC Research Building
Central service facilities of the CCG and the CMMC
Catherin Niemann
member of the CF Tissue Embedding
Christian Frese
member of the CF Proteomics Facility
Jay Gopalakrishnan
member of the CF Microscopy Facility
Janine Altmüller
member of the NGS Platform (CCG)
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Title tba
Elena Rugarli
CECAD Cologne, Univ. of Cologne
RESI Seminar Series
4.00 p.m. – Seminar Room, CMMC Research Building
Cilia induction to prevent proliferation of glioma stem cells in vitro
Gladiola Goranci
member of the RG Gopalakrishnan
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Parallels between wound healing and cancer
Sabine Eming
Dept. of Dermatology, Univ. of Cologne
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Host-directed therapies in mycobacterial infection
Mario Fabri
Department of Dermatology, Univ. of Cologne
RESI Seminar Series
4.00 p.m. – Seminar Room, CMMC Research Building
Genetic heterogeneity in Pakistani microcephaly families
Sajid M. Hussain
member of the RG Nürnberg
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Computational approaches to decipher the cancer genome
Martin Peifer
Dept. of Translational Genomics, Univ. of Cologne
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Florian Klein
Clinic I for Internal Medicine, Univ. of Cologne
CCRC Seminar Series
4.00 p.m. – Seminar Room, CMMC Research Building
Flow-mediated remodeling of resistance arteries and dual role of the angiotensin II receptors
Daniel Henrion
BNMI, INSERM, CNRS, Université d'Angers , Angers, France
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Targeting tumor angiogenesis in solid tumors
Roland Ullrich
Clinic I for Internal Medicine, Univ. of Cologne
RESI Seminar Series
4.00 p.m. – Seminar Room, CMMC Research Building
Epigenetic control of pluripotency enhancers state as a novel germline competence mechanism
Tore Bleckwehl
member of the JRG Alvaro Rada-Iglesias
RESI Seminar Series
4.00 p.m. – Seminar Room, CMMC Research Building
Epigenetic control of pluripotency enhancers state as a novel germline competence mechanism
Jay Gopalakrishnan JRG IX, CMMC, Univ. of Cologne
CMMC Seminar Series
12.00 p.m. – Seminar Room, CMMC Research Building
The role of the Cytoskeleton in Cardiac Conduction
Jeffrey Fields
Perelman School of Medicine University of Pennsylvania
Philadelphia - USA
RESI Seminar Series
4.00 p.m. – Seminar Room, CMMC Research Building
A role for 3D chromatin rearrangements in cellular senescence
Kostas Sofiadis
member of the RG Argyris Papantonis
CMMC Seminar Series
2.00 p.m. – Seminar Room, CMMC Research Building
Disrupted cysteine metabolism in neurodegenerative disorders
Bindu Diana Paul
Johns Hopkins Univ. School of Medicine
Baltimore - USA
CMMC Seminar Series
2.00 p.m. – Seminar Room, CMMC Research Building
Transcriptional and epigenetic regulation during differentiation, development and disease
Henk Stunnenberg
Radboud University Medical Center - Nijmegen, NL
RESI Seminar Series
4.00 p.m. – Seminar Room, CMMC Research Building
Impact of aging on cardiac injury recovery
Gaurav Ahuja
Member of the Kurian Research Group, CMMC, Cologne
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
3D genome reorganization and its implications in signaling and senescence
Argyris Papantonis
CMMC, Cologne
In-house exhibition
Promega GmbH
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Stem cell-specific mechanisms in tumor initiation and progression
Catherin Niemann
Institute for Biochemistry II and CMMC, Cologne
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Cell polarity programs in skin homeostasis, tumor formation and progression
Sandra Iden
CECAD Cologne
RESI Seminar Series
4.00 p.m. – Seminar Room, CMMC Research Building
Centrosome activation: a mechanism to control cancer cell proliferation
Arul Mariappan
Member of the Gopalakrishnan Research Group, CMMC, Cologne
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Control of epithelial cyto-architecture in homeostasis and disease
Carien Niessen
Department of Dermatology and CECAD Cologne
Seminar "Novel Technologies"
11.30 a.m. - 1.00 p.m. – Seminar Room, CMMC Research Building
Improve your CRISPR-Cas9 genome editing workflow with the chemically modified Alt-R™ CRISPR-Cas9 System from IDT
Michel Cannieux
INTEGRATED DNA TECHNOLOGIES (IDT)
Seminar "Novel Technologies"
02.00 - 03.00 p.m. – Mediathek, CMMC Research Building
Multiplex Cytokine Detection in 3ul sample volume
Oliver Gresch
AYOXXA Biosystems GmbH
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Mechanisms underlying brain hippocampal network rewiring in physiology and disease
Matteo Bergami
CECAD Cologne
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Functional and topological characterization of poised enhancers during embryonic stem cell differentiation
Alvaro Rada-Iglesias
CMMC Cologne
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Primary Cilia and Ciliopathies
Bernhard Schermer
Dept. II of Internal Medicine, CECAD Cologne
CMMC Seminar Series
Looking beyond the genes: CRISPR/Cas9 genome editing to investigate non-coding mutations
Malte Spielmann
Institute for Medical and Human Genetics, Charité-Universitätsmedizin Berlin and
Max Planck Institute for Molecular Genetics, Berlin, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
A sweet deal - the role of amino sugars in homeostasis and longevity
Martin Denzel
MPI for Biology of Ageing, Cologne
CMMC Seminar Series
CRISPR/Cas-assisted genome engineering: strategies and applications
Sebastian Bultmann
Faculty of Biology, Dept. II - Human Biology and Bioimaging, LMU Munich, Germany
CCRC Seminar Series
The endothelial glycocalyx in vascular health and disease
Bernard M. van den Berg
Leiden University Medical Center, Leiden, The Netherlands
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
The roles of cytoskeletal organisers in mouse development
Hisham Bazzi
Medical Faculty and CECAD/SFB 829, Cologne
Seminar "Novel Technologies"
10.00 - 11.30 a.m. – Mediathek, CMMC Research Building
"Liquid handling with pipettes and the impact of pipetting technique"
Eppendorf Deutschland GmbH
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Recapitulating human early embryonic development using pluripotent stem cells
Leo Kurian
Institute for Neurophysiology assoc. CMMC-JRG II, Cologne
CCRC Seminar Series
Interaction of vascular dysfunction and myocardium in heart failure
Rolf Wachter
Clinic for Cardiology and Pneumology, University Medicine Göttingen and DZHK (German Cardiovascular Research Centre) partner site Göttingen
RESI Seminar Series
04.00 p.m. – Seminar Room, CMMC Research Building
The paraoxonase PON2 modifies lipid peroxidation and TRPC6-signaling at the glomerular slit diaphragm
Henning Hagmann
Member of the Brinkkötter Research Group – Dept. II for Internal Medicine and CMMC, Cologne
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
The fibrillin microfibril scaffold: A niche for growth factors and mechanosensation?
Gerhard Sengle
Institute for Biochemistry II, Cologne
RESI Seminar Series
04.00 p.m. – Seminar Room, CMMC Research Building
Targeting tumor angiogenesis in cancer
Caroline Volz
Member of Ullrich Research Group, Dept. I of Internal Medicine and CMMC, Cologne
Mol-Med Lecture Series Series
Seminar Room, CMMC Research Building
Biomechanical regulation of epidermal cell fate and morphogenesis
Sara Wickström
MPI for Biology of Ageing, Cologne
CMMC Seminar Series
04.00 p.m. – Seminar Room, CMMC Research Building
AATF sustains global transcription in multiple myeloma through the maintenance of an open chromatin structure
Maurizio Fanciulli
Regina Elena Cancer Institute, Rome, Italy
CMMC Seminar Series
04.00 p.m. – Seminar Room, CMMC Research Building
Programmable RNA Recognition and Tracking with CRISPR/Cas9 in Live Cells
David A Nelles
Dept. of Cellular and Molecular Medicine Materials Science and Engineering Graduate Program University of California - San Diego, USA
Seminar "Novel Technologies"
02.00 p.m. - Seminar Room
Molecular interaction studies using PerkinElmer Technologies
Horst Lauersen (PerkinElmer) and Nadine Fröhlich (Field Application Scientist, PerkinElmer)
PerkinElmer LAS (Germany) GmbH
CMMC Seminar Series
03.00 p.m. – Seminar Room, CMMC Research Building
3C technologies: from studying 3D genome structure and function to non-invasive prenatal diagnosis
Wouter de Laat
Hubrecht Institute-KNAW & University Medical Center Utrecht Utrecht, The Netherlands
RESI Seminar Series
04.00 p.m. – Seminar Room, CMMC Research Building
Genetic and functional characterization of rare adipose tissue disorder
Julia Schreml
Principal Investigator - Institute for Human Genetics, Cologne
CMMC Seminar Series
05.00 p.m. – Seminar Room, CMMC Research Building
suPAR Biology and Kidney Disease
Jochen Reiser
Dept. of Internal Medicine, Rush University Medical Center, Chicago, Illinois
CCRC Seminar Series
05.00 p.m. – Seminar Room, CMMC Research Building
PI3K in airway disease: targeting kinase and scaffold function
Emilio Hirsch
Dept. of Molecular Biotechnology and Health Sciences, Center for Molecular Biotechnology, Italy
RESI Seminar Series
How to teach the immune system to fight cancer?
Hinrich Abken
Principal Investigator - Dept. I of Internal Medicine and CMMC
RESI Seminar Series
04.00 p.m. – Seminar Room, CMMC Research Building
Capturing the native 3D conformation of mammalian genomes
Julia Schreml
Principal Investigator - Institute of Human Genetics
CCRC Seminar Series
05.00 p.m. – Seminar Room, CMMC Research Building
Inhibition of endocannabinoid degradation protects against pulmonary hypertension
Daniela Wenzel and Bernd Fleischmann
Institute of Physiology I, Life & Brain Center, University of Bonn, Germany
RESI Seminar Series
04.00 p.m. – Seminar Room, CMMC Research Building
Capturing the native 3D conformation of mammalian genomes
Lilija Brant
Member of the Papantonis Research Group, CMMC, Cologne
CMMC Seminar Series
Renal stroma cells: functions, plasticity and crucial relevance of dynamic HIF-2
Armin Kurtz
Institut für Physiologie, Universität Regensburg, Germany
RESI Seminar Series
04.00 p.m. – Seminar Room, CMMC Research Building
Adeno-Associated Viral Vectors - from viruses to designer nanoparticles
Hildegard Büning
Principal Investigator - Hannover Medical School and Dept. I / CMMC, Cologne
CMMC Seminar Series
The dynamic epigenome – a challenge to healthy aging and suppression of cancer
Peter D. Adams
The Beaton Institute of Cancer Research, University of Glasgow, United Kingdom
CCRC Seminar Series
05.00 p.m. – Seminar Room, CMMC Research Building
Cell death and inflammation in atherosclerosis
Manolis Pasparakis
Principal Investigator - CECAD Cologne
RESI Seminar Series
Antibody mediated neutralization of HIV1
Daniela Weiland
Member of the Klein Research Group – Dept. I for Internal Medicine / CMMC, Cologne
CCRC Seminar Series
DNA damage responses in aging-associated diseases
Björn Schumacher
CECAD Cologne, Germany
CMMC - Seminar
An unexpected Journey on the Edge of Elastinopathies and Collagenopathie
Bert Callewaert
Gent, Belgium
RESI Seminar Series
Characterization of microRNA biogenesis and decay in Spinal muscular atrophy
Inês do Carmo Gil Gonçalves
CCRC Seminar Series
Discovering non-coding RNAs in the cardiovascular world
Thomas Thum
Hannover Medical School, Hannover, Germany
RESI Seminar Series
Modulation of Rho kinase to improve axonal regeneration
Abhijeet Joshi
CMMC, Cologne, Germany
CCRC Seminar Series
Macrophage-dependent signaling in myocardial hyperterophy
Yeong-Hoon Choi
Dept. III of Internal Medicine, Cologne, Germany
CCRC Seminar Series
Tyrosine kinase signaling in vascular disease
Stephan Rosenkranz
Dept. III of Internal Medicine, Cologne, Germany
RESI Seminar Series
Insights into tumor evolution from genome sequencing data
Cun Yupeng
Cologne, Germany
RESI Seminar Series
Epigenomic based identification of novel patterning regulators
Rizwan Rehimi
Cologne, Germany
CMMC - Seminar
Brain L type calcium channels: new targets for old drugs?
Joerg Striessnig
Innsbruck, Germany
CCRC Seminar Series
Bio-engineering of human myocardium
Wolfram H. Zimmermann
Univ. Medical Ctr. Göttingen, Germany
RESI Seminar Series
Imaging / Tissue Emb. / Cell Sorting / Bioanalytics
Presentation Core Units
CMMC ‐ Seminar
3D genome organization and gene expression control
Peter Fraser
Babraham, England
CCRC Seminar Series
Innate immune cells in CV disease - Role of neutrophils in vascular signaling and structure
Anna Klinke
Dept. III for Internal Medicine, Cologne, Germany
RESI Seminar Series
The role of the PI 3‐Kinase isoform p110alpha for vascular remodeling in experimental pulmonary hypertension
Eva Berghausen
Cologne, Germany
CCRC Special Seminar
Redox-Derived Signaling Mediators and New Drug Candidates
Bruce A Freeman
Pittsburgh, PA, USA
GWAS oder was? Lessons from the Cohorte Lausanoise
Sven Bergmann
Lausanne, French
CCRC Seminar Series
Inflammatory signals in metabolism
Jens Brüning
MPI f. Metabolismus Research/ZEDP, Cologne, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
New CCL treatment option – a perspective view
Christian Reinhardt
Dept. I of Internal Medicine, CCG
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Animal Models used in cancer research
Thorsten Hoppe (CECAD Cologne) and Thomas Wunderlich (Institute for Genetics)
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Leukemia: disease and current therapies from a medical perspective
Christian Reinhardt
Dept. I of Internal Medicine, CCG
RESI Seminar Series
Protective modifier Plastin 3 and its interacting network in neurodegenerative disorders
Mohsen Hosseini
Cologne, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
DNA damage and innate immunity
Elke Pogge-von Strandmann
Dept. I of Internal Medicine
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
The Immune System and Cancer
Hildegard Büning
CMMC and Institute of Exp. Hamatology - Hannover Medical School
CCRC Seminar Series
Cardiac channelopathies - Mechanisms of inherited cardiac rhythm disorders
Daniel Steven
Dept. III of Internal Medicine, Cologne, Germany
RESI Seminar Series
Climate protection measures at the working place in the CMMC Research Building: Your impact? Why? How? Where? When?
Bernd Oerder
Cologne, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
DNA damage-induced cell death; a safe guard system for tissue homeostasis
Hamid Kashkar
Inst. for Med. Microbiology, Immunology & Hygiene (IMMIH)
RESI Seminar Series
A molecular mechanism for adult stem cell maintainance in Drosophila
Li Ming Gooi
Cologne, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
DNA damage detection, response (DDR) and repair
Björn Schumacher
CECAD Cologne, CMMC
CMMC Seminar
Novel strategies to treat proteinuria: Can we heal the actin cytoskeleton?
Mario Schiffer
Hannover, Germany
CCRC Seminar Series
Inflammatory cells in arterial hypertension
Philip Wenzel
Univ. Medicine Mainz, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Molecular diagnostic tools in cancer
Carmen Herling
Dept. I of Internal Medicine
CCRC Seminar Series
Role of the podocyte in glomerular filtration and progressive kidney disease
Thomas Benzing
Dept. II for Internal Medicine, Cologne, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Signaling networks and signal transduction
Christian Reinhardt
Dept. I of Internal Medicine, CCG
RESI Seminar Series
Mechanisms of stem cell-driven skin tumour initiation and differentiation
Karen Reuter
Cologne, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
The B-cell receptor pathway, a new therapeutic target
Christian Pallasch
Dept. I of Internal Medicine, CECAD Cologne
CMMC Seminar
Epigenetic control of the pluripotency network
Pablo Navarro-Gil
Paris, France
CCRC Seminar Series
Mitochondrial dysfunction in disease and aging
Aleksandra Trifunovic
CECAD Cologne, Germany
CCRC Seminar Series
Mini-Symposium:
PhD Student reports and presentation of the CCRC Core Facilities
Cologne, Germany
CMMC Seminar
Proteome TAILS - tools for system-wide determination of proteolysis and protease substrates
Pitter Huesgen
Jülich, Germany
CMMC ‐ Seminar
Enhancer transcription accurately identifies active enhancers and reveals architectures of transcriptional regulation
Robin Andersson
Copenhagen, Denmark
CCRC Seminar Series
Transcription factors and epigenetic networks in pulmonary hypertension
Soni Pullamsetti
MPI Bad Nauheim, Germany
CMMC Seminar
Nephron development and homeostasis - Basic research and clinical implications
Kai M. Schmidt-Ott
Berlin, Germany
CCRC Seminar Series
Innate immune cells in CV disease - Role of neutrophils in cardiac integrity
Volker Rudolph
Dept. III of Internal Medicine, Cologne, Germany
CMMC Seminar
Methods to analyze composition and dynamics of protein complexes
Ilka Wittig
Frankfurt, Germany
CMMC Seminar
Kidney function in older adults - the Berlin Initiative Study
Elke Schäffner
Berlin, Germany
CMMC Seminar
Circadian gene expression in the aging mouse kidney: a change of rhythm
Pål Westermark
Berlin, Germany
Middle and large-scale positional organization of transcription in simple (and not-so-simple) eukaryotes
Christoforos Nikolaou
Crete, Greece
New avenues to understanding proteinuria: An evolutionary approach
Tobias Huber
Freiburg, Germany
The motivation for clinical research - Hereditary tumor diseases of the kidney and the adrenal gland
Hartmut Neumann
Freiburg, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Insulin/IGF signaling in epithelial morphogenesis, homeostasis and carcinogenesis
Carien Niessen
Dept. of Dermatology
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Survival of priceless cells: Active and passive protection of embryonic stem cells
against immune destruction
Olaf Utermöhlen
Institute of Medical Microbiology, Immunology and Hygiene (IMMIH)
Metals in Alzheimer's disease and Parkinson's disease
Ashley I. Bush
Melbourne, Australia
Stability analysis of clonal T-cell populations against (leukemic) invaders
Hans Diebner
Dresden, Germany
Directed evolution approaches
– a powerful technology to improve Adeno-associated viral vectors
Hildegard Büning
CMMC and Institute of Exp. Hematology - Hannover Medical School
Enabling T cell migration to the tumor as a strategy to enhance the efficacy of adoptive T cell therapy
Sebastian Kobold
Munich, Germany
Mol-Med Lecture Series
12.00 p.m. – Seminar Room, CMMC Research Building
Mitochondrial dysfunction in determination of longevity
Aleksandra Trifunovic
Institute for Mitochondrial Diseases and Aging, CECAD
MicroRNA and immune surveillance of tumors
Barbara Seliger
Halle-Wittenberg, Germany
Plexin Signaling in Development and Disease
Thomas Worzfeld
Marburg, Germany
Siglec ligands protect tumor cells from NK cell immunosurveillance
Stephan von Gunten
Bern, Switzerland
Next generation genome engineering - Knocking out genes with CRISPR/Cas9
Stefan Frank
Münster, Germany
Are oxidative and calcium signaling determinants of mitochondrial longevity?
Muniswamy Madesh
Philadelphia, USA
Conserved long non-coding RNAs program vertebrate embryonic development
Leo Kurian
Cologne, Germany
Posttranscriptional regulation by RNA - binding proteins
Markus Landthaler
Berlin, Germany
Membrane cholesterol keeps the TCR in an active state
Wolfgang Schamel
Freiburg, Germany
Designer nucleases and iPSC - novel tools to model and treat chronic immunodeficienc
Toni Cathomen
Freiburg, Germany
"To Be, or not to Be, Monoclonal" The genetics of identical twinning in humans
Bruno Reversade
Singapore
Phagocyte cross-talk in bacterial infection
Christian Kurts
Bonn, Germany
Investigating Prohibitin genetic interactions in the regulation of ageing and metabolism
Marta Artal Sanz
Sevilla, Spain
Redox signaling as cardiovascular all-rounder: the role of PON2 in endothelial stress, blood coagulation and angiogenesis
Sven Horke
Mainz, Germany
Mechanisms of centriole assembly
Pierre Gönczy
Lausanne, Switzerland
The Drosophila nephrocyte - a powerful model for vertebrate podocyte development and function
Michael Krahn
Regensburg, Germany
Kidney and testicular cancer: the link to cilia in the mesonephros
Rachel Giles
Utrecht, Netherlands
Centrosome and Cilia formation in development and disease
Mónica Bettencourt Dias
Oeiras, Portugal