September 26, 2021 - Sunday
12.45 p.m.
Welcome Address
Axel Freimuth - Rector of the University of Cologne
Thomas Krieg - Vice President of the ´Nationale Akademie der Wissenschaften (Leopoldina)
Thomas Benzing - Chair - Center for Molecular Medicine Cologne, University of Cologne
Session I:
Stem Cell Biology and Regenerative Medicine
Chairs: Claus Cursiefen and Carien Niessen (Cologne, DE)
1.00 - 1.10 p.m.
Introduction
of the research field
1.10 - 1.40 p.m.
SARS-CoV-2 genomic integration, expression and cell tropism
Rudolph Jaenisch
Massachusetts Institute of Technology - Cambridge, US
1.40 - 2.10 p.m.
Mechanisms of mammalian cell fate decisions
Thomas Graf
Centre for Genomic Regulation (CRG) - Barcelona, ES
2.10 - 2.40 p.m.
Proteostasis of aging and stem cells
David Vilchez
CECAD - Cologne Excellence Cluster Diseases - Cologne, DE
2.40 - 3.10 p.m.
Hybrid Coffee Break
3.10 - 3.40 p.m.
Single factor induction of divergent cell fates
Konrad Hochedlinger
Massachusetts General Hospital, Harvard Dept. of Stem Cell and Regenerative Biology and Howard Hughes Medical Institute - Boston, US
3.40 - 4.10 p.m.
From melanoma to Parkinson’s disease – applications of human pluripotent stem cells
Lorenz Studer
The Center for Stem Cell Biology, Developmental Biology Program, Memorial Sloan-Kettering Institute for Cancer Research - New York, US
4.10 - 4.40 p.m.
Advanced genetic engineering of hematopoiesis to treat inherited diseases and cancer
Luigi Naldini
San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University - Milan, IT
4.40 - 5.00 p.m.
Hybrid Coffee Break
5.00 - 5.30 p.m.
Introduction - Thomas Krieg (Cologne, DE)
The Center for Molecular Medicine Cologne: the last 25 years and the future
Franz Hofmann
Institute for Pharmacology and Toxicology, Technical University Munich - Munich, DE
5:30 - 5:45 p.m.
Hybrid Coffee Break and "Get ready for the CMMC Poster Session"
Welcome to the CMMC Poster Session
Of note: The CMMC Poster Session has now been integrated directly into the CMMC Symposium Program.
August 27, 2021: Deadline extended for the submission of the poster abstracts - for further information please visit https://www.cmmc-uni-koeln.de/events/cmmc-symposium-2021/poster-session
5.45 - 6.00 p.m.
Welcome Address - Michal-Ruth Schweiger (Cologne, DE)
6.00 - 7.30 p.m.
Presentations of Posters No. 01 - 60
Poster Session MAP 1 and Poster Session MAP 2
7.30 - 9.00 p.m.
Presentations of Posters No. 61 - 120
Poster Session MAP 3 and Poster Session MAP 4
9.00 - 9.10 p.m.
Concluding Remarks - Michal-Ruth Schweiger (Cologne)
September 27, 2021 - Monday
Session II:
Molecular Oncology and Genomic Medicine
Chairs: Reinhard Büttner and Michal-Ruth Schweiger (Cologne, DE)
8.30 - 8.40 a.m.
Introduction
of the research field
8.40 - 9.10 a.m.
Precision oncology: experiences and challenges in translating genomic information into clinical decisions
Peter Lichter
German Cancer Research Center, DKFZ - Heidelberg, DE
9.10 - 9.40 a.m.
Mutational footprints of cancer therapies
Núria López-Bigas
Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology - Barcelona, ES
9.40 - 10.10 a.m.
The Human Cell Atlas: mapping the body one cell at a time
Sarah Teichmann
Cellular Genetics, Wellcome Sanger Institute - Hinxton, GB
10.10 - 10.30 a.m.
Hybrid Coffee Break
10.30 - 11.00 a.m.
Darwinian and Non-Darwinian Evolution in Cancer
Marco Gerlinger
Institute of Cancer Research - London, GB
11.00 - 11.30 a.m.
Mapping childhood brain tumors onto normal cerebellar development
Stefan Pfister
Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg - Heidelberg, DE
11.30 - 12.30 a.m.
Hybrid Lunch Break with hybrid scientifc networking
Session III:
Precision Medicine in Cancer Treatment
Chairs: Michal-Ruth Schweiger and Martin Sos - Cologne, DE
12.30 - 12.40 p.m.
Introduction
of the research field
12.40 - 1.10 p.m.
The role of stress signaling in cancer and cancer treatment
Michael B Yaffe
Massachusetts Institute of Technology, Center for Precision Cancer Medicine and Koch Institute for Integrative Cancer Research - Cambridge, US
1.10 - 1.40 p.m.
Exploiting synthetic lethality in the treatment of cancer
Chris J Lord
Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research - London, GB
1.40 - 2.10 p.m.
The making of diffuse large B cell lymphoma
Laura Pasqualucci
Institute for Cancer Genetics, Columbia University - New York, US
2.10 - 2.30 p.m.
Hybrid Coffee Break
2.30 - 3.00 p.m.
Lymphoma epigenetics
Ari M Melnick
Division of Hematology & Medical Oncology, Sackler Center for Biomedical and Physical Sciences, Weill Cornell Medicine - New York, US
3.00 - 3.30 p.m.
10 years checkpoint blockade - what have we learned?
Dirk Schadendorf
Dept. of Dermatology, University Hospital Essen, Univ. Duisburg - Essen, DE
3.30 - 3.40 p.m.
Announcement of the three CMMC Poster Prize Winners
Michal-Ruth Schweiger (Cologne)
3.40 - 4.00 p.m.
Hybrid Coffee Break
Session IV:
Infectious Diseases
Chairs: Martin Krönke and Jan Rybniker (Cologne, DE)
4.00 - 4.10 p.m.
Introduction
Ralf Bartenschlager
Dept. of Infectious Diseases, University Hospital Heidelberg - Heidelberg, DE
4.10 - 4.40 p.m
Respiratory virus pathogenicity in high-risk groups
Gülsah Gabriel
Heinrich-Pette-Institute, Leibniz Institute for Experimental Virology - Hamburg, DE
4.40 - 5.10 p.m
Antibody-mediated neutralization of SARS-CoV-2
Florian Klein
Institute for Virology, University of Cologne - Cologne DE
5.10 - 5.30 p.m.
Hybrid Coffee Break
5.30 - 6.00 p.m.
Towards a curative therapy for Hepatitis B and D co-infected patients
Stephan Urban
Department of Infectious Diseases, University Hospital Heidelberg - Heidelberg, DE
6.00 - 6.30 p.m.
Vaccines and monoclonals to regain our freedom
Rino Rappuoli
Chief Scientist und Head of External Research and Development (R&D) at GlaxoSmithKline Vaccines - Siena, IT
6.30 - 7.00 p.m.
Survival strategies of malaria parasites in the dry season
Silvia Portugal
Max Planck Institute for Infection Biology - Berlin, DE
September 28, 2021 - Tuesday
Session V:
Neuroplasticity and Neurodegeneration
Chairs: Dirk Isbrandt and Tatiana Korotkova (Cologne, DE)
9.00 - 9.10 a.m.
Introduction
of the research field
9.10 - 9.40 a.m.
Dynamic control of presynaptic function in health and disease
Nils Brose
Dept. of Molecular Neurobiology, Max Planck Institute for Exp. Medicine - Goettingen, DE
9.40 - 10.10 a.m.
Neuronal correlates of emotion states in mice
Nadine Gogolla
Max Planck Institute of Neurobiology - Martinsried, DE
10.10 - 10.40 a.m.
Tau toxicity at the synapse
Patrik Verstreken
VIB-KU Leuven Center for Brain & Disease Research - Leuven, BE
10.40 - 11.00 a.m.
Hybrid Coffee Break
11.00 - 11.30 a.m.
Negative feedback control of neuronal activity by microglia
Anne Schaefer
Friedman Brain Inst. and Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai - New York, US
11.30 - 12.00 p.m.
Mechanisms for fast dopamine signaling
Pascal S Kaeser
Department of Neurobiology, Harvard Medical School - Boston, US
12.00 - 12.15 p.m.
Awarding of the CMMC Poster Prizes and short talks (3x 5 min.) given by the awardees
Michal-Ruth Schweiger (Cologne)
12.15 - 1.00 p.m.
Hybrid Lunch Break with hybrid scientific networking (lunch included for all participants at the venue)
Session VI:
Metabolism and Aging
Chairs: Sabine Eming and Aleksandra Trifunovic (Cologne, DE)
1.00 - 1.10 p.m.
Introduction
of the research field
1.10 - 1.40 p.m.
CNS-dependent control of metabolism
Jens C Bruening
Max Planck Institute for Metabolism Research, CEDPM and CECAD Cologne - Cologne, DE
1.40 - 2.10 p.m.
Hormone sensing in astrocytes for the control of systemic metabolism
Cristina García Cáceres
Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Institute for Diabetes and Obesity - Neuherberg, DE
2.10 - 2.30 p.m.
Hybrid Coffee Break
2.30 - 3.00 p.m.
Reversing the decline in physical activity with age
Lora Heisler
The Rowett Institute, University of Aberdeen - Aberdeen, GB
3.00 - 3.30 p.m.
Mechanisms of stem cell aging and rejuvenation
Anne Brunet
Dept. of Genetics, Stanford University School of Medicine - Stanford, US
3.30 - 4.00 p.m.
The surprising role of glia in the regulation of metabolism and aging
Andrew Dillin
Dept. of Molecular and Cell Biology, University of California Berkeley - Berkeley, US
4.00 - 4.10 p.m.
Summary, open questions, closing remarks and leave-taking
General Information
Registration and participation in the CMMC Symposium "25 Years of Progress in Molecular Medicine" is free of charge!
Please register here
Considering the Covid-19 developments as well as the hygiene measures of the University Hospital Cologne, we regret to inform you that only a limited number of participants will be able to attend the venue in person. We reserved the limited "seats" for the guest speakers and the chairs of the sessions. The few remaining seats will be allocated to "local" participants - strict "2 G regulation) .
We very well know nothing beats a face to face meeting but while we cannot meet in person, we are excited to welcome you as a digital participant at the CMMC Symposium 2021 including the CMMC Poster Session. We have put a lot of effort into making the digital CMMC Symposium as interactive and exciting as possible for all.
If you have further questions, please do not hesitate to contact me or the members of the CMMC Office Team by e-mail: CMMC-Symposium@uni-koeln.de
We are looking forward to welcoming you as virtual participant in the CMMC Symposium 2021 and wish you a stimulating and enjoyable conference with inspiring presentations and fruitful discussions.
With best regards
Debora Grosskopf-Kroiher
For our guest speakers - directions and site map
Program - CMMC Symposium 2021
We gratefully acknowledge support by
Poster - CMMC Symposium 2021
Gerhard Richter
We are delighted, that the Poster 25 Years of Molecular Medicine shows the abstract artwork "Colour-Charts - 1024 Colours - 1974 / Werkverzeichnis 358-1" of Gerhard Richter. This is an outstanding honour for us.
With a career spanning nearly six decades, Gerhard Richter is widely considered one of the greatest artists of our time. To explore the artist's work, please visit: https://www.gerhard-richter.com/de/
Contacts for general information
The meeting is open and no registration or attendance fee is required. Participation is free of charge - free registration is required.
For questions releated to your registration please contact Bettina Kranz - zmmk-office[at]uni-koeln.de