11.30 a.m. - 12.50 p.m.

Reception with Welcome-Lunch

12.50 p.m.

Welcome Address

Thomas Krieg        
Medical Faculty, University of Cologne

Thomas Benzing
Center for Molecular Medicine Cologne, University of Cologne

Opening Remarks

Baki Akgül - Jens Peter Klussmann
Organizers

Session 1: Epidemiology

Chair: Baki Akgül - Institute for Virology, University of Cologne - Cologne, DE

1.00 - 1.30 p.m.

Association of beta-HPV and skin cancer
Herbert Pfister
Institute for Virology, University of Cologne - Cologne, DE

1.30 - 2.00 p.m.

Detection and natural history of HPV infection of oral cavity and tonsils
Ulrike Wieland
Institute for Virology and National Reference Center for Papilloma- and Polyomaviruses, University Hospital of Cologne - Cologne, DE

2.00 - 2.30 p.m.

Immunological control of HPV-driven oropharyngeal cancer
Sjoerd H van der Burg
Dept. of Clinical Oncology, Leiden University Medical Center - Leiden, NL

2.30 - 3.00 p.m.

Coffee Break

Session 2: Immunology

Chair: Jens Peter Klussmann -Dept. of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Cologne - Cologne, DE

3.00 - 3.30 p.m.

What happens between seroconversion and development of HPV positive oropharyngeal cancer?
Tim Waterboer
Infections and Cancer Epidemiology, German Cancer Research Center (DKFZ) - Heidelberg, DE

3.30 - 4.00 p.m.

Homeostasis and adaptation of epithelial transition zone niche: the hot spots of infection and cancer
Cindrilla Chumduri
Dept. of Molecular Biology, Max Planck Institute for InfectionBiology - Berlin, DE
 

4.00 - 4.30 p.m.

Tumor microenvironment as biomarker of HPV positive oropharyngeal cancer?
Anders Näsman
Dept. of Oncology-Pathology, Karolinska Institute - Stockholm, SE

4.30 - 5.00 p.m.

Coffee Break

Session 3: Genomics

Chair: Alexander Quaas - Institute for Pathology, University Hospital Cologne - Cologne, DE

5.00 - 5.30 p.m.

Mutation signature in epithelial cancer
Julie George
Dept. of Translational Genomics, University Hospital Cologne - Cologne, DE

5.30 - 6.00 p.m.

Causes and consequences of HPV integration in oropharyngeal cancer
Ernst-Jan M Speel
Dept. of Pathology, Maastricht University Medical Center - Maastricht, NL

6.00 - 6.30 p.m.

Genomic signature of HPV positive oropharyngeal cancer
Ruud H Brakenhoff
Amsterdam UMC, Vrije Universiteit Amsterdam, Otolaryngology-Head and Neck Surgery, Cancer Center Amsterdam - Amsterdam, NL

6.30 - 9.00 p.m.

Invitation of the Get-Together "Missing Link in HPV Biology" at the venue

free finger food and drinks

Session 4: Stem cell and differentiation

Chair: Paola Zigrino - Dept. of Dermatology, University Hospital Cologne - Cologne, DE

9.00 - 9.30 a.m.

Cancer stem cells in HPV-related cancer
Michael Herfs
Laboratory of Exp. Pathology, GIGA Cancer, University of Liege - Liege, BE

9.30 - 10.00 a.m.

Role of skin stem cells in beta-HPV carcinogenesis
Girish Patel
European Cancer Stem Cell Research Institute, School of Bioscience, Cardiff University - Cardiff, GB

10.00 - 10.15 a.m.

Coffee Break

10.15 - 10.45 a.m.

Mastomys coucha as animal model to understand cutaneous HPV carcinogenesis
Frank Rösl
Division of Viral Transformation Mechanisms, German Cancer Research - Heidelberg, DE

10.45 - 11.15 a.m.

HPV oncoproteins manipulate epithelial differentiation
Elizabeth White
Dept. of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine - Philadelphia, US

11.15 - 11.30 a.m.

Coffee Break

Session 5: Carcinogenesis

Chair: Gertrud Steger - Institute for Virology, University Hospital Cologne - Cologne, DE

11.30 - 12.00 a.m.

Metabolic stress in HPV positive oropharyngeal cancer
Christian Hübbers
Jean-Uhrmacher-Institute for Otorhinolaryngological Research, University of Cologne - Cologne, DE

12.00 - 12.30 p.m.

Interference of HPV with DNA damage and repair pathway
Nicholas N Wallace
Division of Biology, Kansas State University- Manhattan, US

12.30 - 1.00 p.m.

Cutaneous papillomaviruses: from mice to men
Karl Münger
Dept. of Developmental Molecular and Chemical Biology, Tufts University School of Medicine - Boston, US

1.00 - 1.45 p.m.

Lunch Break

Session 6: Epigenetics

Chair: Michal-Ruth Schweiger - Laboratory - Functional Epigenome, University of Cologne - Cologne, DE

1.45 - 2.15 p.m.

Epigenetic and autophagic changes in skin cancer
Daniele Bergamaschi
Centre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University - London, GB

2.15 - 2.45 p.m.

Methylation of the HPV genome
Magnus von Knebel Doeberitz
Dept. of Applied Tumor Biology, Institute of Pathology, University Hospital of Heidelberg and German Cancer Research Center - Heidelberg, DE

2.45 - 3.15 p.m.

The methylome and miRNA profile in HPV positive cancer
Jochen Hess
Dept. of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Heidelberg - Heidelberg, DE

3.15 - 3.30 p.m.

Concluding remarks

Baki Akgüland Jens Peter Klussmann
University of Cologne and University Hospital of Cologne