8.30 - 9.45 a.m.

Internal Meeting of the CMMC Executive Board

(for members of the CMMC Executive Board only / ausschließlich für die Mitglieder des Geschäftsführenden Vorstands des CMMC)

Seminar Room - located in the MTI Lecture Hall Building

Scientific Program

Venue: Lecture and Foyer of the MTI-Lecture Hall Building of the Faculty of Medicine

9.00 - 9.45 a.m.

Reception - in the Foyer

Poster Session Info - We kindly ask all participants presenting posters at the Poster Session (5.00 - 7.00 p.m.) to place their posters on the poster boards in the foyer by 10:45 a.m. at the latest. Our aim is to promote the scientific exchange during all breaks.

10.00 - 10.05 a.m.

Welcome Address

Thomas Benzing - Chair of the Center for Molecular Medicine Cologne

Short Talk Session I

Research Area C - Molecular Mechanisms and Metabolic Control of Tissue Degeneration and Regeneration

Chairs: Débora Trentini I Robert Hänsel-Hertsch

10.05 - 10.20 a.m.

C 13 - Role of TNF-mediated inflammatory signaling in heart failure with preserved ejection fraction (HFpEF) and associated pulmonary hypertension (PH)
Stephan Rosenkranz | Marius Vantler - Clinic III for Internal Medicine

10.20 a.m - 10.35 a.m.

C 08 - Dissecting the role of Alzheimer’s disease-associated endocytosis risk factors in regulating cell cycle events in neuronal cells
Natalia Kononenko - Institute for Physiology and Pathophysiology

10.35 - 10.50 a.m

C 10 - Triaging of secretory cargo by interplay of TANGO1 and ERAD-R
Marius Lemberg¹ | Alvise Schiavinato² | Julian Nüchel³- ¹Center for Biochemistry | ²Clinic for Pediatric and Adolescent Medicine | ³MPI for Biology of Aging

10.50 - 11.10 a.m.

Coffee Break

11.10 - 11.25 a.m.

CAP 25 - Targeting endosomal removal of mitochondrial nucleoids to modulate mtDNA heteroplasmy
David Pla-Martin - Institute of Vegetative Physiology

11.25 - 11.50 a.m.

C 17 - Bioactive lipid signaling in adult neurogenesis and metabolic modulation
Johannes Vogt | Lara-Jane Kepser - Dept. of Molecular and Translational Neurosciences

11.50 - 12.05 p.m.

C 04 - Unlocking tissue protective and regenerative functions of myeloid cells by metabolic reprograming
Sebastian Willenborg I Mario Fabri I Sabine Eming
Clinic of Dermatology and Venereology

12.05 - 12.30 p.m.

CMMC Report
Thomas Benzing - Chair of the Center for Molecular Medicine Cologne 

12.30 - 1.30 p.m.

Lunch Break with catering at the venue

Short Talk Session II

Research Area B - Principles of Immunity, Inflammation and Infection

Chairs: Alessandro Annibaldi I Hans Schlößer

1.30 - 1.45 p.m.

B 03 / CAP 21 - Metabolic control of T cell immunity
Mauro Corrado - CECAD Research Center

1.45 - 2.00 p.m.

CAP 22 - Myeloid Cells in Systemic and Cardiovascular Inflammation
Friedrich Hoyer - Clinic III for Internal Medicine

2.00 - 2.15 p.m.

B 05 - Targeting the osmosensitive transcription factor NFAT5 in acute and chronic corneal edema
Karina Hadrian | Claus Cursiefen| Deniz Hos - Clinic of General Ophthalmology

2.15 - 2.35 p.m.

Coffee Break

2.35 - 2.50 p.m.

assoc. JRG 07 I CAP 26 - Dynamics and durability of HIV-1 neutralization are determined by viral replicatio
Philipp Schommers - Clinic I for Internal Medicine

2.50 - 3.05 p.m.

CAP 27 - Development of patient-derived PcrV antibodies targeting Pseudomonas aeruginosa
Alexander Simonis - Clinic I for Internal Medicine

3.05 - 3.20 p.m.

B 04 - Endothelial cells and pericytes in cutaneous leishmaniasis
Jonathan Jantsch - Institute for Medical Microbiology, Immunology and Hygiene

3.20 - 3.35 p.m.

Coffee Break

Short Talk Session III

Research Area A - Mechanisms of tumor development: intrinsic and extrinsic control of cell proliferation and tissue invasion

Chairs: Nieves Peltzer | Simon Pöpsel

3.35 - 3.50 p.m.

A 01 - The mitotic surveillance pathway in stem cells
Hisham Bazzi - Clinic of Dermatology and Venerology

3.50 - 4.05 p.m.

A 06 - Identification of therapeutic vulnerabilities of KEAP1-mutated lung adenocarcinoma
Axel Hillmer | Reinhard Büttner - Institute of Pathology

4.05 - 4.20 p.m.

A 05 - The dialogue of CLL cells with the tumor microenvironment as a mediator of treatment resistance against targeted inhibitor combinations
Lukas Frenzel | Michael Hallek - Clinic I of Internal Medicine

4.20 - 5.00 p.m.

CMMC Lecture

Introduction and moderation - Thomas Benzing

Universal computational machines for digital pathology
Katarzyna Bozek - Center for Molecular Medicine Cologne & Institute of Biomedical Information

5.00 - 7.30 p.m.

Poster Session

with Get-Together (with catering at the venue)

5.30 - 6.30 p.m. - Even Poster Numbers
6.30 - 7.30 p.m. - Uneven Poster Numbers