Center for Molecular Medicine Cologne

Summary of articles published by CMMC members in 2019

Selected publications related to CMMC-projects are listed in alphabetical order by the first author published in 2019.

  • Acharya A, Brungs S, Lichterfeld Y, Hescheler J, Hemmersbach R, Boeuf H, and Sachinidis A (2019). Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes. Cells 8.

  • Ackermann S, and Fischer M (2019). Telomere Maintenance in Pediatric Cancer. Int J Mol Sci 20.

  • Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling JE, Dodzian J, Lagerborg KA, Vargas NE, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano DR, and Kurian L (2019). Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep 20.

  • Albrecht W, Kappenberg F, Brecklinghaus T, Stoeber R, Marchan R, Zhang M, Ebbert K, Kirschner H, Grinberg M, Leist M, Moritz W, Cadenas C, Ghallab A, Reinders J, Vartak N, van Thriel C, Golka K, Tolosa L, Castell JV, Damm G, Seehofer D, Lampen A, Braeuning A, Buhrke T, Behr AC, Oberemm A, Gu X, Kittana N, van de Water B, Kreiling R, Fayyaz S, van Aerts L, Smedsrod B, Ellinger-Ziegelbauer H, Steger-Hartmann T, Gundert-Remy U, Zeigerer A, Ullrich A, Runge D, Lee SML, Schiergens TS, Kuepfer L, Aguayo-Orozco A, Sachinidis A, Edlund K, Gardner I, Rahnenfuhrer J, and Hengstler JG (2019). Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations. Arch Toxicol 93, 1609-37.

  • Alcala N, Leblay N, Gabriel AAG, Mangiante L, Hervas D, Giffon T, Sertier AS, Ferrari A, Derks J, Ghantous A, Delhomme TM, Chabrier A, Cuenin C, Abedi-Ardekani B, Boland A, Olaso R, Meyer V, Altmuller J, Le Calvez-Kelm F, Durand G, Voegele C, Boyault S, Moonen L, Lemaitre N, Lorimier P, Toffart AC, Soltermann A, Clement JH, Saenger J, Field JK, Brevet M, Blanc-Fournier C, Galateau-Salle F, Le Stang N, Russell PA, Wright G, Sozzi G, Pastorino U, Lacomme S, Vignaud JM, Hofman V, Hofman P, Brustugun OT, Lund-Iversen M, Thomas de Montpreville V, Muscarella LA, Graziano P, Popper H, Stojsic J, Deleuze JF, Herceg Z, Viari A, Nuernberg P, Pelosi G, Dingemans AMC, Milione M, Roz L, Brcic L, Volante M, Papotti MG, Caux C, Sandoval J, Hernandez-Vargas H, Brambilla E, Speel EJM, Girard N, Lantuejoul S, McKay JD, Foll M, and Fernandez-Cuesta L (2019). Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids. Nat Commun 10, 3407.

  • Aleksandrova K, Leise J, Priesner C, Melk A, Kubaink F, Abken H, Hombach A, Aktas M, Essl M, Burger I, Kaiser A, Rauser G, Jurk M, Goudeva L, Glienke W, Arseniev L, Esser R, and Kohl U (2019). Functionality and Cell Senescence of CD4/ CD8-Selected CD20 CAR T Cells Manufactured Using the Automated CliniMACS Prodigy(R) Platform. Transfus Med Hemother 46, 47-54.

  • Anton V, Buntenbroich I, Schuster R, Babatz F, Simoes T, Altin S, Calabrese G, Riemer J, Schauss A, and Escobar-Henriques M (2019). Plasticity in salt bridge allows fusion-competent ubiquitylation of mitofusins and Cdc48 recognition. Life Sci Alliance 2.

  • Argenziano MA, Doss MX, Tabler M, Sachinidis A, and Antzelevitch C (2019). Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis. PLoS One 14, e0216928.

  • Arthuis CJ, Nizon M, Komhoff M, Beck BB, Riehmer V, Bihouee T, Bruel A, Benbrik N, Winer N, and Isidor B (2019). A step towards precision medicine in management of severe transient polyhydramnios: MAGED2 variant. J Obstet Gynaecol 39, 395-7.

  • Asif M, Kaygusuz E, Brancati F, Nienberg C, Nickelsen A, Jose J, Hochscherf J, Niefind K, Noegel AA, Nurnberg P, and Hussain MS (2019). De novo mutation of CSNK2B encoding beta subunit of casein kinase 2 causes Filippi syndrome. European Journal of Human Genetics 27, 1504-5.

  • Assady S, Benzing T, Kretzler M, and Skorecki KL (2019). Glomerular podocytes in kidney health and disease. Lancet 393, 856-8.

  • Augustin M, Horn C, Koch J, de Silva US, Platten M, Nierhoff D, Suarez I, Chon SH, Rybniker J, and Lehmann C (2019). Short Communication: Tracking Tregs: Translocation of CD49b/LAG-3(+) Type 1 T Regulatory Cells to the Gut-Associated Lymphoid Tissue of HIV+ Patients. Aids Research and Human Retroviruses 35, 247-50.

  • Ayachi O, Barlin M, Broxtermann PN, Kashkar H, Mauch C, and Zigrino P (2019). The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival. Cell Oncol (Dordr) 42, 319-29.

  • Bachmann B, Handel A, Siebelmann S, Matthaei M, and Cursiefen C (2019). Mini-Descemet Membrane Endothelial Keratoplasty for the Early Treatment of Acute Corneal Hydrops in Keratoconus. Cornea 38, 1043-8.

  • Bachurski D, Schuldner M, Nguyen PH, Malz A, Reiners KS, Grenzi PC, Babatz F, Schauss AC, Hansen HP, Hallek M, and Pogge von Strandmann E (2019). Extracellular vesicle measurements with nanoparticle tracking analysis - An accuracy and repeatability comparison between NanoSight NS300 and ZetaView. J Extracell Vesicles 8, 1596016.

  • Balser C, Wolf A, Herb M, and Langmann T (2019). Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina. J Neuroinflammation 16, 26.

  • Bamborschke D, Pergande M, Daimaguler HS, Mangold E, Dotsch J, Herkenrath P, Cirak S, and Fazeli W (2019). Cleft Palate as Distinguishing Feature in a Patient with GABRB3 Epileptic Encephalopathy. Neuropediatrics 50, 378-81.

  • Bankov K, Doring C, Ustaszewski A, Giefing M, Herling M, Cencioni C, Spallotta F, Gaetano C, Kuppers R, Hansmann ML, and Hartmann S (2019). Fibroblasts in Nodular Sclerosing Classical Hodgkin Lymphoma Are Defined by a Specific Phenotype and Protect Tumor Cells from Brentuximab-Vedotin Induced Injury. Cancers (Basel) 11.

  • Bauer CK, Schneeberger PE, Kortum F, Altmuller J, Santos-Simarro F, Baker L, Keller-Ramey J, White SM, Campeau PM, Gripp KW, and Kutsche K (2019). Gain-of-Function Mutations in KCNN3 Encoding the Small-Conductance Ca(2+)-Activated K(+) Channel SK3 Cause Zimmermann-Laband Syndrome. Am J Hum Genet 104, 1139-57.

  • Bayersdorf R, and Schumacher B (2019). Recent advances in understanding the mechanisms determining longevity. F1000Res 8.

  • Beielstein AC, and Pallasch CP (2019). Tumor Metabolism as a Regulator of Tumor-Host Interactions in the B-Cell Lymphoma Microenvironment-Fueling Progression and Novel Brakes for Therapy. Int J Mol Sci 20.

  • Bendell JC, Bischoff HG, Hwang J, Reinhardt HC, Zander T, Wang X, Hynes S, Pitou C, Campbell R, Iversen P, Farrington DL, Bell-McGuinn K, and Thomas M (2019). A phase 1 dose-escalation study of checkpoint kinase 1 (CHK1) inhibitor prexasertib in combination with p38 mitogen-activated protein kinase (p38 MAPK) inhibitor ralimetinib in patients with advanced or metastatic cancer. Invest New Drugs 10.1007/s10637-019-00873-6.

  • Bender D, Kaczmarek AT, Santamaria-Araujo JA, Stueve B, Waltz S, Bartsch D, Kurian L, Cirak S, and Schwarz G (2019a). Impaired mitochondrial maturation of sulfite oxidase in a patient with severe sulfite oxidase deficiency. Hum Mol Genet 10.1093/hmg/ddz109.

  • Bender D, Tobias Kaczmarek A, Niks D, Hille R, and Schwarz G (2019b). Mechanism of nitrite-dependent NO synthesis by human sulfite oxidase. Biochem J 476, 1805-15.

  • Berghausen EM, Feik L, Zierden M, Vantler M, and Rosenkranz S (2019). Key inflammatory pathways underlying vascular remodeling in pulmonary hypertension. Herz 44, 130-7.

  • Bleckwehl T, and Rada-Iglesias A (2019). Transcriptional and epigenetic control of germline competence and specification. Curr Opin Cell Biol 61, 1-8.

  • Bolduc V, Foley AR, Solomon-Degefa H, Sarathy A, Donkervoort S, Hu Y, Chen GS, Sizov K, Nalls M, Zhou H, Aguti S, Cummings BB, Lek M, Tukiainen T, Marshall JL, Regev O, Marek-Yagel D, Sarkozy A, Butterfield RJ, Jou C, Jimenez-Mallebrera C, Li Y, Gartioux C, Mamchaoui K, Allamand V, Gualandi F, Ferlini A, Hanssen E, Group CAIS, Wilton SD, Lamande SR, MacArthur DG, Wagener R, Muntoni F, and Bonnemann CG (2019). A recurrent COL6A1 pseudoexon insertion causes muscular dystrophy and is effectively targeted by splice-correction therapies. JCI Insight 4.

  • Bonig H, Kuci Z, Kuci S, Bakhtiar S, Basu O, Bug G, Dennis M, Greil J, Barta A, Kallay KM, Lang P, Lucchini G, Pol R, Schulz A, Sykora KW, Teichert von Luettichau I, Herter-Sprie G, Ashab Uddin M, Jenkin P, Alsultan A, Buechner J, Stein J, Kelemen A, Jarisch A, Soerensen J, Salzmann-Manrique E, Hutter M, Schafer R, Seifried E, Paneesha S, Novitzky-Basso I, Gefen A, Nevo N, Beutel G, Schlegel PG, Klingebiel T, and Bader P (2019). Children and Adults with Refractory Acute Graft-versus-Host Disease Respond to Treatment with the Mesenchymal Stromal Cell Preparation "MSC-FFM"-Outcome Report of 92 Patients. Cells 8.

  • Borchmann S, Cirillo M, Goergen H, Meder L, Sasse S, Kreissl S, Brockelmann PJ, von Tresckow B, Fuchs M, Ullrich RT, and Engert A (2019). Pretreatment Vitamin D Deficiency Is Associated With Impaired Progression-Free and Overall Survival in Hodgkin Lymphoma. Journal of Clinical Oncology 37, 3528-+.

  • Braun F, Blomberg L, Brodesser S, Liebau MC, Schermer B, Benzing T, and Kurschat CE (2019a). Enzyme Replacement Therapy Clears Gb3 Deposits from a Podocyte Cell Culture Model of Fabry Disease but Fails to Restore Altered Cellular Signaling. Cell Physiol Biochem 52, 1139-50.

  • Braun F, Suarez V, Dinter J, Haneder S, Quaas A, Benzing T, Nierhoff D, and Muller RU (2019b). Successful use of TNF alpha blockade in a severe case of idiopathic non-granulomatous ulcerative jejunoileitis associated with thrombotic thrombocytopenic purpura. Bmj Open Gastroenterology 6.

  • Bredart A, Kop JL, Antoniou AC, Cunningham AP, De Pauw A, Tischkowitz M, Ehrencrona H, Schmidt MK, Dolbeault S, Rhiem K, Easton DF, Devilee P, Stoppa-Lyonnet D, and Schmutlzer R (2019). Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey. J Community Genet 10, 61-71.

  • Brinkkoetter PT, Bork T, Salou S, Liang W, Mizi A, Ozel C, Koehler S, Hagmann HH, Ising C, Kuczkowski A, Schnyder S, Abed A, Schermer B, Benzing T, Kretz O, Puelles VG, Lagies S, Schlimpert M, Kammerer B, Handschin C, Schell C, and Huber TB (2019a). Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics. Cell Rep 27, 1551-66 e5.

  • Brinkkoetter PT, Grundmann F, Ghassabeh PJ, Becker I, Johnsen M, Suarez V, Schulz RJ, Streichert T, and Burst V (2019b). Impact of Resolution of Hyponatremia on Neurocognitive and Motor Performance in Geriatric Patients. Sci Rep 9, 12526.

  • Burgmaier K, Kilian S, Bammens B, Benzing T, Billing H, Buscher A, Galiano M, Grundmann F, Klaus G, Mekahli D, Michel-Calemard L, Milosevski-Lomic G, Ranchin B, Sauerstein K, Schaefer S, Shroff R, Sterenborg R, Verbeeck S, Weber LT, Wicher D, Wuhl E, Dotsch J, Schaefer F, and Liebau MC (2019). Clinical courses and complications of young adults with Autosomal Recessive Polycystic Kidney Disease (ARPKD). Sci Rep 9, 7919.

  • Bustos BI, Perez-Palma E, Buch S, Azocar L, Riveras E, Ugarte GD, Toliat M, Nurnberg P, Lieb W, Franke A, Hinz S, Burmeister G, von Schonfels W, Schafmayer C, Volzke H, Volker U, Homuth G, Lerch MM, Santos JL, Puschel K, Bambs C, Roa JC, Gutierrez RA, Hampe J, De Ferrari GV, and Miquel JF (2019). Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry. Sci Rep 9, 772.

  • Buttner C, Clahsen T, Regenfuss B, Dreisow ML, Steiber Z, Bockt F, Reis A, and Cursiefen C (2019). Tyrosinase Is a Novel Endogenous Regulator of Developmental and Inflammatory Lymphangiogenesis. American Journal of Pathology 189, 440-8.

  • Campbell K, Shyr D, Bagatell R, Fischer M, Nakagawara A, Nieto AC, Brodeur GM, Matthay KK, London WB, and DuBois SG (2019). Comprehensive evaluation of context dependence of the prognostic impact of MYCN amplification in neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project. Pediatr Blood Cancer 66, e27819.

  • Canepa M, Franssen FME, Olschewski H, Lainscak M, Bohm M, Tavazzi L, and Rosenkranz S (2019). Diagnostic and Therapeutic Gaps in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease. JACC Heart Fail 7, 823-33.

  • Caskey M, Klein F, and Nussenzweig MC (2019). Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic. Nat Med 25, 547-53.

  • Castiglione R, Alidousty C, Holz B, Wagener S, Baar T, Heydt C, Binot E, Zupp S, Kron A, Wolf J, Merkelbach-Bruse S, Reinhardt HC, Buettner R, and Schultheis AM (2019). Comparison of the genomic background of MET-altered carcinomas of the lung: biological differences and analogies. Mod Pathol 32, 627-38.

  • Cheng Y, Luo H, Izzo F, Pickering BF, Nguyen D, Myers R, Schurer A, Gourkanti S, Bruning JC, Vu LP, Jaffrey SR, Landau DA, and Kharas MG (2019). m(6)A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment. Cell Rep 28, 1703-16 e6.

  • Chmielewski M, Kuehle J, Chrobok D, Riet N, Hallek M, and Abken H (2019). FimH-based display of functional eukaryotic proteins on bacteria surfaces. Sci Rep 9, 8410.

  • Choi YJ, Halbritter J, Braun DA, Scheeler M, Schapiro D, Rim JH, Nandadasa S, Choi WI, Widmeier E, Shril S, Korber F, Sethi SK, Lifton RP, Beck BB, Apte SS, Gee HY, and Hildebrandt F (2019). Mutations of ADAMTS9 Cause Nephronophthisis-Related Ciliopathy. American Journal of Human Genetics 104, 45-54.

  • Clayton RW, Gobel K, Niessen CM, Paus R, van Steensel MAM, and Lim X (2019). Homeostasis of the sebaceous gland and mechanisms of acne pathogenesis. Br J Dermatol 10.1111/bjd.17981.

  • Cosolo A, Jaiswal J, Csordas G, Grass I, Uhlirova M, and Classen AK (2019). JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress. Elife 8.

  • Czibere L, Burggraf S, Fleige T, Gluck B, Keitel LM, Landt O, Durner J, Roschinger W, Hohenfellner K, Wirth B, Muller-Felber W, Vill K, and Becker M (2019). High-throughput genetic newborn screening for spinal muscular atrophy by rapid nucleic acid extraction from dried blood spots and 384-well qPCR. Eur J Hum Genet 10.1038/s41431-019-0476-4.

  • da Silva PFL, and Schumacher B (2019). DNA damage responses in ageing. Open Biol 9, 190168.

  • Dafsari HS, Kawalia A, Sprute R, Karakaya M, Malenica A, Herkenrath P, Nurnberg P, Motameny S, Thiele H, and Cirak S (2019a). Novel mutations in SLC6A5 with benign course in hyperekplexia. Cold Spring Harb Mol Case Stud 5.

  • Dafsari HS, Kocaturk NM, Daimaguler HS, Brunn A, Dotsch J, Weis J, Deckert M, and Cirak S (2019b). Bi-allelic mutations in uncoordinated mutant number-45 myosin chaperone B are a cause for congenital myopathy. Acta Neuropathol Commun 7, 211.

  • Dafsari HS, Sprute R, Wunderlich G, Daimaguler HS, Karaca E, Contreras A, Becker K, Schulze-Rhonhof M, Kiening K, Karakulak T, Kloss M, Horn A, Pauls A, Nurnberg P, Altmuller J, Thiele H, Assmann B, Koy A, and Cirak S (2019c). Novel mutations in KMT2B offer pathophysiological insights into childhood-onset progressive dystonia. J Hum Genet 64, 803-13.

  • Dammert MA, Bragelmann J, Olsen RR, Bohm S, Monhasery N, Whitney CP, Chalishazar MD, Tumbrink HL, Guthrie MR, Klein S, Ireland AS, Ryan J, Schmitt A, Marx A, Ozretic L, Castiglione R, Lorenz C, Jachimowicz RD, Wolf E, Thomas RK, Poirier JT, Buttner R, Sen T, Byers LA, Reinhardt HC, Letai A, Oliver TG, and Sos ML (2019). MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer. Nat Commun 10, 3485.

  • De Rechter S, Bockenhauer D, Guay-Woodford LM, Liu I, Mallett AJ, Soliman NA, Sylvestre LC, Schaefer F, Liebau MC, Mekahli D, Adamczyk P, Akinci N, Alpay H, Ardelean C, Ayasreh N, Aydin Z, Bael A, Baudouin V, Bayrakci US, Bensman A, Bialkevich H, Biebuyck A, Boyer O, Bjanid O, Brylka A, Caliskan S, Cambier A, Camelio A, Carbone V, Charbit M, Chiodini B, Chirita A, Cicek N, Cerkauskiene R, Collard L, Conceicao M, Constantinescu I, Couderc A, Crapella B, Cvetkovic M, Dima B, Diomeda F, Docx M, Dolan N, Dossier C, Drozdz D, Drube J, Dunand O, Dusan P, Eid LA, Emma F, Hernandez ME, Fila M, Furlano M, Gafencu M, Ghuysen M, Giani M, Giordano M, Girisgen I, Godefroid N, Godron-Dubrasquet A, Gojkovic I, Gonzalez E, Gokce I, Groothoff JW, Guarino S, Guffens A, Hansen P, Harambat J, Haumann S, He G, Heidet L, Helmy R, Hemery F, Hooman N, Ilanas B, Jankauskiene A, Janssens P, Karamaria S, Kazyra I, Koenig J, Krid S, Krug P, Kwon V, La Manna A, Leroy V, Litwin M, Lombet J, Longo G, Lungu AC, Mallawaarachchi A, Marin A, Marzuillo P, Massella L, Mastrangelo A, McCarthy H, Miklaszewska M, Moczulska A, Montini G, Morawiec-Knysak A, Morin D, Murer L, Negru I, Nobili F, Obrycki L, Otoukesh H, Ozcan S, Pape L, Papizh S, Parvex P, Pawlak-Bratkowska M, Prikhodina L, Prytula A, Quinlan C, Raes A, Ranchin B, Ranguelov N, Repeckiene R, Ronit C, Salomon R, Santagelo R, Saygili SK, Schaefer S, Schreuder M, Schurmans T, Seeman T, Segers N, Sinha M, Snauwaert E, Spasojevic B, Stabouli S, Stoica C, Stroescu R, Szczepanik E, Szczepanska M, Taranta-Janusz K, Teixeira A, Thumfart J, Tkaczyk M, Torra R, Torres D, Tram N, Utsch B, Vande Walle J, Vieux R, Vitkevic R, Wilhelm-Bals A, Wuhl E, Yildirim ZY, Yuksel S, Zachwieja K, and Consortium A (2019). ADPedKD: A Global Online Platform on the Management of Children With ADPKD. Kidney International Reports 4, 1271-84.

  • Delle Vedove A, Storbeck M, Eckenweiler M, Hosseinibarkooie S, Ferreira NM, Heller R, Holker I, Magnusson O, Korber F, Kye M, Kirschner J, and Wirth B (2019). A de novo mutation of the stress granules-associated CAPRIN1 causes a novel progressive neurodegenerative disorder. European Journal of Human Genetics 27, 1473-4.

  • Di Bella DJ, Carcagno AL, Bartolomeu ML, Pardi MB, Lohr H, Siegel N, Hammerschmidt M, Marin-Burgin A, and Lanuza GM (2019). Ascl1 Balances Neuronal versus Ependymal Fate in the Spinal Cord Central Canal. Cell Rep 28, 2264-74 e3.

  • Dias Gomes M, Letzian S, Saynisch M, and Iden S (2019). Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity. Nat Commun 10, 3362.

  • Ding X, Willenborg S, Bloch W, Wickstrom SA, Wagle P, Brodesser S, Roers A, Jais A, Bruning JC, Hall MN, Ruegg MA, and Eming SA (2019). Epidermal mTORC2 controls lipid synthesis and filaggrin processing in epidermal barrier formation. J Allergy Clin Immunol 10.1016/j.jaci.2019.07.033.

  • Doll MA, Soltanmohammadi N, and Schumacher B (2019). ALG-2/AGO-Dependent mir-35 Family Regulates DNA Damage-Induced Apoptosis Through MPK-1/ERK MAPK Signaling Downstream of the Core Apoptotic Machinery in Caenorhabditis elegans. Genetics 213, 173-94.

  • Doring M, Kreer C, Lehnen N, Klein F, and Pfeifer N (2019). Modeling the Amplification of Immunoglobulins through Machine Learning on Sequence-Specific Features. Sci Rep 9, 10748.

  • Dork T, Peterlongo P, Mannermaa A, Bolla MK, Wang Q, Dennis J, Ahearn T, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Augustinsson A, Freeman LEB, Beckmann MW, Beeghly-Fadiel A, Behrens S, Bermisheva M, Blomqvist C, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Burwinkel B, Canzian F, Chan TL, Chang-Claude J, Chanock SJ, Choi JY, Christiansen H, Clarke CL, Couch FJ, Czene K, Daly MB, Dos-Santos-Silva I, Dwek M, Eccles DM, Ekici AB, Eriksson M, Evans DG, Fasching PA, Figueroa J, Flyger H, Fritschi L, Gabrielson M, Gago-Dominguez M, Gao C, Gapstur SM, Garcia-Closas M, Garcia-Saenz JA, Gaudet MM, Giles GG, Goldberg MS, Goldgar DE, Guenel P, Haeberle L, Haiman CA, Hakansson N, Hall P, Hamann U, Hartman M, Hauke J, Hein A, Hillemanns P, Hogervorst FBL, Hooning MJ, Hopper JL, Howell T, Huo D, Ito H, Iwasaki M, Jakubowska A, Janni W, John EM, Jung A, Kaaks R, Kang D, Kapoor PM, Khusnutdinova E, Kim SW, Kitahara CM, Koutros S, Kraft P, Kristensen VN, Kwong A, Lambrechts D, Marchand LL, Li J, Lindstrom S, Linet M, Lo WY, Long J, Lophatananon A, Lubinski J, Manoochehri M, Manoukian S, Margolin S, Martinez E, Matsuo K, Mavroudis D, Meindl A, Menon U, Milne RL, Mohd Taib NA, Muir K, Mulligan AM, Neuhausen SL, Nevanlinna H, Neven P, Newman WG, Offit K, Olopade OI, Olshan AF, Olson JE, Olsson H, Park SK, Park-Simon TW, Peto J, Plaseska-Karanfilska D, Pohl-Rescigno E, Presneau N, Rack B, Radice P, Rashid MU, Rennert G, Rennert HS, Romero A, Ruebner M, Saloustros E, Schmidt MK, Schmutzler RK, Schneider MO, Schoemaker MJ, Scott C, Shen CY, Shu XO, Simard J, Slager S, Smichkoska S, Southey MC, Spinelli JJ, Stone J, Surowy H, Swerdlow AJ, Tamimi RM, Tapper WJ, Teo SH, Terry MB, Toland AE, Tollenaar R, Torres D, Torres-Mejia G, Troester MA, Truong T, Tsugane S, Untch M, Vachon CM, Ouweland A, Veen EMV, Vijai J, Wendt C, Wolk A, Yu JC, Zheng W, Ziogas A, Ziv E, Investigators A, Collaborators N, Dunning AM, Pharoah PDP, Schindler D, Devilee P, and Easton DF (2019). Two truncating variants in FANCC and breast cancer risk. Sci Rep 9, 12524.

  • Doz F, Locatelli F, Baruchel A, Blin N, De Moerloose B, Frappaz D, Dworzak M, Fischer M, Stary J, Fuertig R, Riemann K, Taube T, and Reinhardt D (2019). Phase I dose-escalation study of volasertib in pediatric patients with acute leukemia or advanced solid tumors. Pediatr Blood Cancer 66, e27900.

  • Drossler L, Lehmann C, Topelt K, Nierhoff D, Vehreschild JJ, Rybniker J, Hallek M, Fischer J, Stormberg V, Fatkenheuer G, Wieland U, and Jung N (2019). HBsAg-negative/anti-HBc-positive patients treated with rituximab: prophylaxis or monitoring to prevent hepatitis B reactivation? Infection 47, 293-300.

  • Du J, Sudarsanam M, Perez-Palma E, Ganna A, Francioli L, Iqbal S, Niestroj LM, Leu C, Weisburd B, Poterba T, Nurnberg P, Daly MJ, Palotie A, May P, and Lal D (2019). Variant Score Ranker-a web application for intuitive missense variant prioritization. Bioinformatics 35, 4478-9.

  • Easo J, Weymann A, Holzl P, Horst M, Eichstaedt H, Mashhour A, Zhigalov K, Szczechowicz M, Thomas RP, Sabashnikov A, and Dapunt OE (2019). Hospital Results of a Single Center Database for Stentless Xenograft Use in a Full Root Technique in Over 970 Patients. Sci Rep 9, 4371.

  • Edem P, Karakaya M, Wirth B, Okur TD, and Yis U (2019). Giant axonal neuropathy: A differential diagnosis of consideration. Turk J Pediatr 61, 275-8.

  • Eftychi C, Schwarzer R, Vlantis K, Wachsmuth L, Basic M, Wagle P, Neurath MF, Becker C, Bleich A, and Pasparakis M (2019). Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment. Immunity 51, 367-80 e4.

  • Eghbalzadeh K, Georgi L, Louis T, Zhao H, Keser U, Weber C, Mollenhauer M, Conforti A, Wahlers T, and Paunel-Gorgulu A (2019). Compromised Anti-inflammatory Action of Neutrophil Extracellular Traps in PAD4-Deficient Mice Contributes to Aggravated Acute Inflammation After Myocardial Infarction. Front Immunol 10, 2313.

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