Summary of articles published by CMMC members in 2011
Selected publications related to CMMC-projects are listed in alphabetical order by the first author published in 2011.
Ackermann S, Goeser F, Schulte JH, Schramm A, Ehemann V, Hero B, Eggert A, Berthold F, and Fischer M (2011). Polo-like kinase 1 is a therapeutic target in high-risk neuroblastoma. Clin Cancer Res 17, 731-741.
Afanasyeva EA, Mestdagh P, Kumps C, Vandesompele J, Ehemann V, Theissen J, Fischer M, Zapatka M, Brors B, Savelyeva L, Sagulenko V, Speleman F, Schwab M, and Westermann F (2011). MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. Cell Death Differ 18, 974-984.
Akgul B, Bauer B, Zigrino P, Storey A, Mauch C, and Pfister H (2011). Upregulation of lipocalin-2 in human papillomavirus-positive keratinocytes and cutaneous squamous cell carcinomas. J Gen Virol 92, 395-401.
Alikhani N, Berglund AK, Engmann T, Spanning E, Vogtle FN, Pavlov P, Meisinger C, Langer T, and Glaser E (2011). Targeting Capacity and Conservation of PreP Homologues Localization in Mitochondria of Different Species. J Mol Bio 410, 400-410.
Alnawaiseh M, Albanna W, Chen CC, Campbell KP, Hescheler J, Luke M, and Schneider T (2011). Two separate Ni(2+) -sensitive voltage-gated Ca(2+) channels modulate transretinal signalling in the isolated murine retina. Acta Ophthalmol 89, e579-e590.
Anton F, Fres JM, Schauss A, Pinson B, Praefcke GJ, Langer T, and Escobar-Henriques M (2011). Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion. J Cell Sci 124, 1126-1135.
Arweiler-Harbeck D, Horsthemke B, Jahnke K, and Hennies HC (2011). Genetic Aspects of Familial Meniere's Disease. Otology & Neurotology 32, 695-700.
Bareyre FM, Garzorz N, Lang C, Misgeld T, Buning H, and Kerschensteiner M (2011). In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration. Proc Natl Acad Sci U S A 108, 6282-6287.
Baris OR, Klose A, Kloepper JE, Weiland D, Neuhaus JFG, Schauen M, Wille A, Muller A, Merkwirth C, Langer T, Larsson NG, Krieg T, Tobin DJ, Paus R, and Wiesner RJ (2011). The Mitochondrial Electron Transport Chain Is Dispensable for Proliferation and Differentiation of Epidermal Progenitor Cells. Stem Cells 29, 1459-1468.
Becker J, Semler O, Gilissen C, Li Y, Bolz HJ, Giunta C, Bergmann C, Rohrbach M, Koerber F, Zimmermann K, de Vries P, Wirth B, Schoenau E, Wollnik B, Veltman JA, Hoischen A, and Netzer C (2011). Exome sequencing identifies truncating mutations in human SERPINF1 in autosomal-recessive osteogenesis imperfecta. Am J Hum Genet 88, 362-371.
Benzing T, and Schermer B (2011).Transition zone proteins and cilia dynamics. Nat Genet 43, 723-724.
Beyer M, Thabet Y, Muller RU, Sadlon T, Classen S, Lahl K, Basu S, Zhou XY, Bailey-Bucktrout SL, Krebs W, Schonfeld EA, Bottcher J, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, Endl E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Mayer G, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, and Schultze JL (2011). Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol 12, 898-U125.
Bilkovski R, Schulte DM, Oberhauser F, Mauer J, Hampel B, Gutschow C, Krone W, and Laudes M (2011). Adipose tissue macrophages inhibit adipogenesis of mesenchymal precursor cells via wnt-5a in humans. Int J Obes (Lond) 35, 1450-1454.
Bissels U, Wild S, Tomiuk S, Hafner M, Scheel H, Mihailovic A, Choi YH, Tuschl T, and Bosio A (2011). Combined Characterization of microRNa and mRNa Profiles Delineates Early Differentiation Pathways of CD133(+) and CD34(+) Hematopoietic Stem and Progenitor Cells. Stem Cells 29, 847-857.
Blaydon DC, Nitoiu D, Eckl KM, Cabral RM, Bland P, Hausser I, van Heel DA, Rajpopat S, Fischer J, Oji V, Zvulunov A, Traupe H, Hennies HC , and Kelsell DP (2011). Mutations in CSTA, Encoding Cystatin A, Underlie Exfoliative Ichthyosis and Reveal a Role for This Protease Inhibitor in Cell-Cell Adhesion. Am J Hum Genet 89, 564-571.
Bock G, Gebhart M, Scharinger A, Jangsangthong W, Busquet P, Poggiani C, Sartori S, Mangoni ME, Sinnegger-Brauns MJ, Herzig S, Striessnig J, and Koschak A (2011). Functional properties of a newly identified C-terminal splice variant of Cav1.3 L-type Ca2+ channels. J Biol Chem, 286, 42736-48.
Bonn F, Tatsuta T, Petrungaro C, Riemer J, and Langer T (2011). Presequence-dependent folding ensures MrpL32 processing by the m-AAA protease in mitochondria. Embo Journal 30, 2545-2556.
Bonnet MC, Preukschat D, Welz PS, van Loo G, Ermolaeva MA, Bloch W, Haase I, and Pasparakis M (2011). The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity 35, 572-582.
Borck G, Ur Rehman A, Lee K, Pogoda HM, Kakar N, von Ameln S, Grillet N, Hildebrand MS, Ahmed ZM, Nurnberg G, Ansar M, Basit S, Javed Q, Morell RJ, Nasreen N, Shearer AE, Ahmad A, Kahrizi K, Shaikh RS, Ali RA, Khan SN, Goebel I, Meyer NC, Kimberling WJ, Webster JA, Stephan DA, Schiller MR, Bahlo M, Najmabadi H, Gillespie PG, Nuernberg P, Wollnik B, Riazuddin S, Smith RJ, Ahmad W, Muller U, Hammerschmidt M, Friedman TB, Leal SM, Ahmad J, and Kubisch C (2011). Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42. Am J Hum Genet 88, 127-137.
Borck G, Wunram H, Steiert A, Volk AE, Korber F, Roters S, Herkenrath P, Wollnik B, Morris-Rosendahl DJ, and Kubisch C (2011). A homozygous RAB3GAP2 mutation causes Warburg Micro syndrome. Hum Genet 129, 45-50.
Bouter A, Gounou C, Berat R, Tan S, Gallois B, Granier T, d'Estaintot BL, Poschl E, Brachvogel B, and Brisson AR (2011). Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair. Nat Commun 2, 270.
Brellier F, Ruggiero S, Zwolanek D, Martina E, Hess D, Brown-Luedi M, Hartmann U, Koch M, Merlo A, Lino M, and Chiquet-Ehrismann R (2011). SMOC1 is a tenascin-C interacting protein over-expressed in brain tumors. Matrix Biol 30, 225-233.
Caglayan E, Vantler M, Leppanen O, Gerhardt F, Mustafov L, ten Freyhaus H, Kappert K, Odenthal M, Zimmermann WH, Tallquist MD, and Rosenkranz S (2011). Disruption of Platelet-Derived Growth Factor-Dependent Phosphatidylinositol 3-Kinase and Phospholipase C gamma 1 Activity Abolishes Vascular Smooth Muscle Cell Proliferation and Migration and Attenuates Neointima Formation In Vivo. J Am Coll Cardiol 57, 2527-2538.
Chaudhry A, Samstein RM, Treuting P, Liang YQ, Pils MC, Heinrich JM, Jack RS, Wunderlich FT, Bruning JC, Muller W, and Rudensky AY (2011). Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation. Immunity 34, 566-578.
Chiang LY, Poole K, Oliveira BE, Duarte N, Sierra YAB, Bruckner-Tuderman L, Koch M, Hu J, and Lewin GR (2011). Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons. Nat Neurosci 14, 993-U979.
Chmielewski M, Hombach AA, and Abken H (2011). CD28 cosignalling does not affect the activation threshold in a chimeric antigen receptor-redirected T-cell attack. Gene Ther 18, 62-72.
Chmielewski M, Kopecky C, Hombach AA, and Abken H (2011). IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression. Cancer Res 71, 5697-5706.
Choi YH, Saric T, Nasseri B, Huhn S, Van Linthout S, Hetzer R, Tschope C, and Stamm C (2011) Cardiac cell therapies: the next generation. Cardiovasc Ther 29, 2-16.
Cianfarani F, Bernardini S, De Luca N, Dellambra E, Tatangelo L, Tiveron C, Niessen CM, Zambruno G, Castiglia D, and Odorisio T (2011) Impaired keratinocyte proliferative and clonogenic potential in transgenic mice overexpressing 14-3-3sigma in the epidermis. J Invest Dermatol 131, 1821-1829.
Dafinger C, Liebau MC, Elsayed SM, Hellenbroich Y, Boltshauser E, Korenke GC, Fabretti F, Janecke AR, Ebermann I, Nurnberg G, Nuernberg P, Zentgraf H, Koerber F, Addicks K, Elsobky E, Benzing T, Schermer B, and Bolz HJ (2011). Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics. J Clin Invest 121, 2662-2667.
de Kreuk BJ, Nethe M, Fernandez-Borja M, Anthony EC, Hensbergen PJ, Deelder AM, Plomann M, and Hordijk PL (2011). The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration. J Cell Sci 124, 2375-2388.
Dolmans GH, Werker PM, Hennies HC, Furniss D, Festen EA, Franke L, Becker K, van der Vlies P, Wolffenbuttel BH, Tinschert S, Toliat MR, Nothnagel M, Franke A, Klopp N, Wichmann HE, Nuernberg P, Giele H, Ophoff RA, Wijmenga C, Grp DDS, Grp GDS, Study LC, and Consortium B-G (2011). Wnt Signaling and Dupuytren's Disease. New Engl J Med 365, 307-317.
Draube A, Klein-Gonzalez N, Mattheus S, Brillant C, Hellmich M, Engert A, and von Bergwelt-Baildon M (2011). Dendritic Cell Based Tumor Vaccination in Prostate and Renal Cell Cancer: A Systematic Review and Meta-Analysis. Plos One 6. e18801
Dykstra T, Utermoehlen O, and Haas A (2011). Defined particle ligands trigger specific defense mechanisms of macrophages. Innate Immun 17, 388-402.
Eckl KM, Alef T, Torres S, and Hennies HC (2011). Full-Thickness Human Skin Models for Congenital Ichthyosis and Related Keratinization Disorders. J Invest Dermatol 131, 1938-1942.
Ehlken H, Kondylis V, Heinrichsdorff J, Ochoa-Callejero L, Roskams T, and Pasparakis M (2011). Hepatocyte IKK2 Protects Mdr2 Mice from Chronic Liver Failure. PLoS One 6, e25942.
Eigentler TK, Figl A, Krex D, Mohr P, Mauch C, Rass K, Bostroem A, Heese O, Koelbl O, Garbe C, and Schadendorf D (2011). Number of metastases, serum lactate dehydrogenase level, and type of treatment are prognostic factors in patients with brain metastases of malignant melanoma. Cancer 117, 1697-1703.
Eming SA, and Hubbell JA (2011). Extracellular matrix in angiogenesis: dynamic structures with translational potential. Exp Dermatol 20, 605-613.
Fatima A, Xu G, Kaifeng S, Papadopoulos S, da Rosa A, Arnaiz Cot JJ, Lehmann M, Nguemo F, Matzkies M, Dittmann S, Stone SL, Linke M, Zechner U, Beyer V, Hennies HC, Rosenkranz S, Klauke B, Farr M, Parwani AS, Cleemann L, Morad M, Milting H, Hescheler J, and Šarić T (2011). In vitro modeling of ryanodine receptor 2 dysfunction using induced pluripotent stem cells. Cell Physiol Biochem 28, 579-592.
Fehrenschild D, Galli U, Breiden B, Bloch W, Schettina P, Brodesser S, Michels C, Gunschmann C, Sandhoff K, Niessen CM, and Niemann C (2011). TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function. J Invest Dermatol 132, 337-345.
Feitosa NM, Richardson R, Bloch W, and Hammerschmidt M (2011). Basement membrane diseases in zebrafish. Meth Cell Biol 105, 191-222.
Feldkirchner S, Mueller S, Kress W, Hanisch FG, Schoser B, and Schessl J (2011). Evaluation of standardized protein pattern of skeletal muscle fibers via laser microdissection. Neuromuscular Disord 21, 739-740.
Feldkirchner S, Walter MC, Kubny C, Mueller S, Kress W, Hanisch FG, Schoser B, and Schessl J (2011). The C224W FHL1 mutation is causing a protein aggregation disorder of muscle: Two brothers revisited. Neuromuscular Disord 21, 740.
Frenzel LP, Patz M, Pallasch CP, Brinker R, Claasen J, Schulz A, Hallek M, Kashkar H, and Wendtner CM (2011). Novel X-linked inhibitor of apoptosis inhibiting compound as sensitizer for TRAIL-mediated apoptosis in chronic lymphocytic leukaemia with poor prognosis. Brit J Haematol 152, 191-200.
Gahete MD, Cordoba-Chacon J, Anadumaka CV, Lin Q, Bruning JC, Kahn CR, Luque RM, and Kineman RD (2011). Elevated GH/IGF-I, Due to Somatotrope-Specific Loss of Both IGF-I and Insulin Receptors, Alters Glucose Homeostasis and Insulin Sensitivity in a Diet-Dependent Manner. Endocrinology 152, 4852-4837.
Galldiks N, Burghaus L, Dohmen C, Teschner S, Pollok M, Leebmann J, Frischmuth N, Hollinger P, Nazli N, Fassbender C, Klingel R, Benzing T, Fink GR, and Haupt WF (2011). Immunoadsorption in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy with Unsatisfactory Response to First-Line Treatment. Eur Neurol 66, 183-189.
Gara SK, Grumati P, Squarzoni S, Sabatelli P, Urciuolo A, Bonaldo P, Paulsson M, and Wagener R (2011). Differential and restricted expression of novel collagen VI chains in mouse. Matrix Biology 30, 248-257.
Gerdes F, Tatsuta T, and Langer T (2011). Mitochondrial AAA proteases - Towards a molecular understanding of membrane-bound proteolytic machines. Biochim Biophys Acta 1823, 49-55.
Grellscheid S*, Dalgliesh C*, Storbeck S*, Best A, Liu Y, Jakubik M, Mende Y, Ehrmann I, Curk T, Kristina Rossbach K, Bourgeois CF, Stevenin J, Grellscheid D, Jackson MS, Wirth B and Elliott DJ (2011) A transcriptome-wide analysis identifies evolutionarily conserved exons as regulated targets for the splicing activator Tra2β. Plos Genetics, e1002390.
Groma G, Grskovic I, Schael S, Ehlen HWA, Wagener R, Fosang A, Aszodi A, Paulsson M, Brachvogel B, and Zaucke F (2011). Matrilin-4 is processed by ADAMTS-5 in late Golgi vesicles present in growth plate chondrocytes of defined differentiation state. Matrix Biol 30, 275-280.
Habbig S, Bartram M, Mueller RU, Schwarz R, Saegmueller J, Liebau M, Benzing T, and Schermer B (2011). Nephrozystin-4 is a negative regulator of hippo signaling. Pediatr Nephrol 26, 1722-1722.
Habbig S, Bartram MP, Muller RU, Schwarz R, Andriopoulos N, Chen SH, Sogmuller JG, Hoehne M, Burst V, Liebau MC, Reinhardt HC, Benzing T, and Schermer B (2011). NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway. J Cell Biol 193, 633-642.
Hanisch FG (2011). Top-Down Sequencing of O-Glycoproteins by In-Source Decay Matrix-Assisted Laser Desorption Ionization Mass Spectrometry for Glycosylation Site Analysis. Analytical Chemistry 83, 4829-4837.
Hansen U, Platz N, Becker A, Bruckner P, Paulsson M, and Zaucke F (2011). A secreted variant of cartilage oligomeric matrix protein carrying a chondrodysplasia-causing mutation (p.H587R) disrupts collagen fibrillogenesis. Arthritis Rheum 63, 159-167.
Hedrych-Ozimina A, Behrendt K, Hao Z, Pofahl R, Ussath D, Knaup R, Krieg T, and Haase I (2011). Enhanced contact allergen- and UVB-induced keratinocyte apoptosis in the absence of CD95/Fas/Apo-1. Cell Death Differ 18, 155-163.
Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rotig A, Nurnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Muller D, Beissert A, Mir S, Berdeli A, Varpizen S, Zenker M, Matejas V, Santos-Ocana C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nuernberg P, Clarke CF, Wiggins RC, Faul C, and Hildebrandt F (2011). COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest 121, 2013-2024.
Heidel AJ, Lawal HM, Felder M, Schilde C, Helps NR, Tunggal B, Rivero F, John U, Schleicher M, Eichinger L, Platzer M, Noegel AA, Schaap P, and Glockner G (2011). Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication. Genome Res 21, 1882-1891.
Henrich KO, Bauer T, Schulte J, Ehemann V, Deubzer H, Gogolin S, Muth D, Fischer M, Benner A, König R, Schwab M & Westermann F (2011). CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programmes in neuroblastoma cells. Cancer Res, 71, 3142-3151.
Hildebrandt F, Benzing T, and Katsanis N (2011). Mechanisms of Disease: Ciliopathies. New Engl J Med 364, 1533-1543.
Hinrichs S, Heger J, Schreckenberg R, Wenzel S, Euler G, Arens C, Bader M, Rosenkranz S, Caglayan E, and Schluter KD (2011). Controlling cardiomyocyte length: the role of renin and PPAR-gamma. Cardiovasc Res 89, 344-352.
Hoffmann DC, Textoris C, Oehme F, Klaassen T, Goppelt A, Romer A, Fugmann B, Davidson JM, Werner S, Krieg T, and Eming SA (2011). Pivotal Role for alpha 1-Antichymotrypsin in Skin Repair. J Biol Chem 286, 28889-28901.
Hohne M, Lorscheider J, von Bardeleben A, Dufner M, Scharf MA, Godel M, Helmstadter M, Schurek EM, Zank S, Gerke P, Kurschat C, Sivritas SH, Neumann-Haefelin E, Huber TB, Reinhardt HC, Schauss AC, Schermer B, Fischbach KF, and Benzing T (2011). The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins. Mol Cell Biol 31, 3241-3251.
Hombach AA, and Abken H (2011).Costimulation by chimeric antigen receptors revisited the T cell antitumor response benefits from combined CD28-OX40 signalling. Int J Cancer 129, 2935-2944.
Hornle M, Peters N, Thayaparasingham B, Vorsmann H, Kashkar H, and Kulms D (2011). Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis. Oncogene 30, 575-587.
Hoesel M, Broxtermann M, Janicki H, Esser K, Arzberger S, Hartmann P, Gillen S, Kleeff J, Stabenow D, Odenthal M, Knolle P, Hallek M, Protzer U, and Buening H (2011). TLR2-mediated innate immune response in human non-parenchymal liver cells towards adeno-associated viral (AAV) vectors. Hepatology 55,287-297.
Huang L, Szymanska K, Jensen VL, Janecke AR, Innes AM, Davis EE, Frosk P, Li C, Willer JR, Chodirker BN, Greenberg CR, McLeod DR, Bernier FP, Chudley AE, Müller T, Shboul M, Logan CV, Loucks CM, Beaulieu CL, Bowie RV, Bell SM, Adkins J, Zuniga FI, Ross KD, Wang J, Ban MR, Becker C, Nürnberg P, Douglas S, Craft CM, Akimenko MA, Hegele RA, Ober C, Utermann G, Bolz HJ, Bulman DE, Katsanis N, Blacque OE, Doherty D, Parboosingh JS, Leroux MR, Johnson CA, Boycott KM (2011). TMEM237 Is Mutated in Individuals with a Joubert Syndrome Related Disorder and Expands the Role of the TMEM Family at the Ciliary Transition Zone. Am J Hum Genet 89,713-30.
Huebner AK, Gandia M, Frommolt P, Maak A, Wicklein EM, Thiele H, Altmüller J, Wagner F, Viñuela A, Aguirre LA, Moreno F, Maier H, Rau I, Giesselmann S, Nürnberg G, Gal A, Nürnberg P, Hübner CA, del Castillo I, Kurth I (2011). Nonsense mutations in SMPX, encoding a protein responsive to physical force, result in X-chromosomal hearing loss. Am J Hum Genet 88, 621-7.
Hufbauer M, Lazic D, Reinartz M, Akgul B, Pfister H, and Weissenborn SJ (2011). Skin tumor formation in human papillomavirus 8 transgenic mice is associated with a deregulation of oncogenic miRNAs and their tumor suppressive targets. J Dermatol Sci 64, 7-15.
Hult S, Soylu R, Bjorklund T, Belgardt BF, Mauer J, Bruning JC, Kirik D, and Petersen A (2011). Mutant Huntingtin Causes Metabolic Imbalance by Disruption of Hypothalamic Neurocircuits. Cell Metabolism 13, 428-439.
Huntgeburth M, La Rosee K, ten Freyhaus H, Bohm M, Schnabel P, Hellmich M, and Rosenkranz S (2011). The Arg389Gly beta(1)-adrenoceptor gene polymorphism influences the acute effects of beta-adrenoceptor blockade on contractility in the human heart. Clin Res Cardiol 100, 641-647.
Huntgeburth M, Laudes M, Burst V, Kramer S, Reuter H, and Rosenkranz S (2011). Acute cardiac arrest secondary to severe hyperkalemia due to autoimmune polyendocrine syndrome type II. Clin Res Cardiol 100, 379-382.
Ikeda F, Deribe YL, Skanland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJ, Goswami P, Nagy V, Terzic J, Tokunaga F, Androulidaki A, Nakagawa T, Pasparakis M, Iwai K, Sundberg JP, Schaefer L, Rittinger K, Macek B, and Dikic I (2011). SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappaB activity and apoptosis. Nature 471, 637-641.
Illich DJ, Demir N, Stojkovic M, Scheer M, Rothamel D, Neugebauer J, Hescheler J, and Zoller JE (2011). Concise review: induced pluripotent stem cells and lineage reprogramming: prospects for bone regeneration. Stem Cells 29, 555-563.
Iorga B, Neacsu CD, Neiss WF, Wagener R, Paulsson M, Stehle R, and Pfitzer G (2011). Micromechanical function of myofibrils isolated from skeletal and cardiac muscles of the zebrafish. J Gen Physiol 137, 255-270.
Izu Y, Sun M, Zwolanek D, Veit G, Williams V, Cha B, Jepsen KJ, Koch M, and Birk DE (2011). Type XII collagen regulates osteoblast polarity and communication during bone formation. J Cell Biol 193, 1115-1130.
Jangsangthong W, Kuzmenkina E Böhnke AK, Herzig S (2011) Single-Channel Monitoring of Reversible L-Type Ca2+ Channel CaValpha1-Subunit Interaction. Biophysical Journal 101, 2661-2670.
John von Freyend, M., Untergasser, A., Arzberger, S., Oberwinkler, H., Drebber, U., Schirmacher, P., and Protzer, U. (2011). Sequential control of hepatitis B virus in a mouse model of acute, self-resolving hepatitis B. J Viral Hepat,18, 216-26.
Jordan SD, Kruger M, Willmes DM, Redemann N, Wunderlich FT, Bronneke HS, Merkwirth C, Kashkar H, Olkkonen VM, Bottger T, Braun T, Seibler J, and Bruning JC (2011). Obesity-induced over expression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nature Cell Biology 13, 434-464.
Kalay E, Yigit G, Aslan Y, Brown KE, Pohl E, Bicknell LS, Kayserili H, Li Y, Tuysuz B, Nurnberg G, Kiess W, Koegl M, Baessmann I, Buruk K, Toraman B, Kayipmaz S, Kul S, Ikbal M, Turner DJ, Taylor MS, Aerts J, Scott C, Milstein K, Dollfus H, Wieczorek D, Brunner HG, Hurles M, Jackson AP, Rauch A, Nuernberg P, Karaguzel A, and Wollnik B (2011). CEP152 is a genome maintenance protein disrupted in Seckel syndrome. Nat Genet 43, 23-26.
Kardakaris R, Gareus R, Xanthoulea S, and Pasparakis M (2011). Endothelial and macrophage-specific deficiency of P38alpha MAPK does not affect the pathogenesis of atherosclerosis in ApoE-/- mice. PLoS One 6, e21055.
Kirschner N, Haftek M, Niessen CM, Behne MJ, Furuse M, Moll I, and Brandner JM (2011). CD44 regulates tight-junction assembly and barrier function. J Invest Dermatol 131, 932-943.
Klatt AR, Becker AKA, Neacsu CD, Paulsson M, and Wagener R (2011). The matrilins: Modulators of extracellular matrix assembly. Int J Biochem Cell Biol 43, 320-330.
Klockener T, Hess S, Belgardt BF, Paeger L, Verhagen LAW, Husch A, Sohn JW, Hampel B, Dhillon H, Zigman JM, Lowell BB, Williams KW, Elmquist JK, Horvath TL, Kloppenburg P, and Bruning JC (2011). High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nature Neuroscience 14, 911-918.
Koch M, Hussein F, Woeste A, Grundker C, Frontzek K, Emons G, and Hawighorst T (2011). CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo. Breast Cancer Res Tr 128, 337-346.
Kofler DM, Chmielewski M, Rappl G, Hombach A, Riet T, Schmidt A, Hombach AA, Wendtner CM, and Abken H (2011). CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activation. Mol Ther 19, 760-767.
Konner AC, and Bruning JC (2011). Toll-like receptors: linking inflammation to metabolism. Trends Endocrinol Metab 22, 16-23.
Konner AC, Hess S, Tovar S, Mesaros A, Sanchez-Lasheras C, Evers N, Verhagen LAW, Bronneke HS, Kleinridders A, Hampel B, Kloppenburg P, and Bruning JC (2011). Role for Insulin Signaling in Catecholaminergic Neurons in Control of Energy Homeostasis. Cell Metabolism 13, 720-728.
Krenzer S, Peterziel H, Mauch C, Blaber SI, Blaber M, Angel P, and Hess J (2011). Expression and function of the kallikrein-related peptidase 6 in the human melanoma microenvironment. J Invest Dermatol 131, 2281-2288.
Kriegeskorte A, Konig S, Sander G, Pirkl A, Mahabir E, Proctor RA, von Eiff C, Peters G, and Becker K (2011). Small colony variants of Staphylococcus aureus reveal distinct protein profiles. Proteomics 11, 2476-2490.
Krone W, Hanefeld M, Meyer HF, Jung T, Bartlett M, Yeh CM, Rajman I, Prescott MF, and Dole WP (2011). Comparative efficacy and safety of aliskiren and irbesartan in patients with hypertension and metabolic syndrome. J Hum Hypertens 25, 186-195.
Krug C, Birkholz K, Abken H, Schwenkert M, Fey G, Schuler G, Dorrie J, and Schaft N (2011). Reprogramming T cells with MHC-independent chimeric antigen receptors specific for MCSP. Exp Dermatol 20, 183-184.
Küchler S, Henkes D, Eckl KM, Ackermann K, Plendl J, Korting HC, Hennies HC, and Schäfer-Korting M (2011). Hallmarks of atopic skin in vitro – mimicked by the means of a skin disease model based on FLG knock down. Altern Lab Anim 39, 471-480.
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