Eming, Sabine | Fabri, Mario - C 04

Unlocking tissue protective and regenerative functions of myeloid cells by metabolic reprograming

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Prof. Dr. Sabine Eming
Prof. Dr. Sabine Eming

Dept. of Dermatology and Venereology

CMMC - Chair
CMMC - PI - C 05 (TP)

sabine.eming@uni-koeln.de

0221 478 3196

Lab Website

CMMC Profile Page

Curriculum Vitae (CV)

Publications on PubMed

Dept. of Dermatology and Venereology

Kerpener Str. 62

50937 Cologne

Introduction

The laboratory is localized in the Department of Dermatology at the University of Cologne. The group has a longstanding expertise in the understanding of cell-cell and cell-matrix interactions relevant to different aspects of tissue remodeling and repair. Research involves a broad range of in vitro and in vivo models to analyze the function of diverse types of skin cells. These include a number of cellular systems (monolayer cultures, complex co-cultures), but also the investigation of genetically modified mouse models. In cooperation with other investigators the group also studies cellular communications in Drosophila and Zebrafish. State of the art technologies for molecular and cell biology are in place (FACS analysis, microarray analysis, time labs video microscopy, confocal microscopy) or are accessible through the Service Laboratory of the CMMC or close collaborations with other groups at the Campus of the University (MPI for Biology of Ageing, MPI for Metabolism Research, Excellence Cluster Cellular Stress Responses in Ageing-Associated Diseases).

Lab Website

For information about Prof. Eming's and Prof. Fabri's research and work, please visit the following page: Eming Group and Fabri Lab

Affiliations - Sabine Eming

Affiliations - Mario Fabri

Clinic of Dermatology and Venereology, University and University Clinic of Cologne

Publication Record on PubMed - Sabine Eming

Publication Record on PubMed - Mario Fabri

2025
  • Klapproth H, Tantcheva-Poór I, Fabri M. Necrobiotic Xanthogranuloma. Br J Dermatol. 2025 Jun 23:ljaf241. doi: 10.1093/bjd/ljaf241. Epub ahead of print. PMID: 40581343.
     
  • Klapproth H, Kubacki T, Fabri M, von Stebut E. Kutane Manifestationen der Sarkoidose [Cutaneous manifestations of sarcoidosis]. Dermatologie (Heidelb). 2025 Apr;76(4):231-243. German. doi: 10.1007/s00105-025-05491-3. Epub 2025 Mar 11. PMID: 40067499.
     
  • Bopp L, Deresz N, Fabri M, von Stebut E. Treatment of cutaneous larva migrans. J Dtsch Dermatol Ges. 2025 Mar;23(3):381-383. doi: 10.1111/ddg.15611. Epub 2025 Jan 6. PMID: 39760251; PMCID: PMC11887020.
     
  • Willenborg S, Schönborn K, Sawant M, Bornikoel A, Yamane T, Zeinert I, Eckes B, Eming SA, Krieg T. Fibroblast-Derived TGFβ1 Regulates Skin Repair and Fibrosis. Wound Repair Regen. 2025 Jul-Aug;33(4):e70065. doi: 10.1111/wrr.70065. PMID: 40652530; PMCID: PMC12256102.
2024
  • Bopp L, Martinez ML, Schumacher C, Seitz R, Arana MH, Klapproth H, Lukas D, Oh JH, Neumayer D, Lackmann JW, Mueller S, von Stebut E, Brachvogel B, Brodesser S, Klein Geltink RI, and Fabri M (2024). Glutamine promotes human CD8(+) T cells and counteracts imiquimod-induced T cell hyporesponsiveness. iScience27, 109767. doi:10.1016/j.isci.2024.109767.
     
  • Injarabian L, Willenborg S, Welcker D, Sanin DE, Pasparakis M, Kashkar H, and Eming SA (2024). FADD- and RIPK3-Mediated Cell Death Ensures Clearance of Ly6C(high) Wound Macrophages from Damaged Tissue. J Invest Dermatol144, 152-164 e157. doi:10.1016/j.jid.2023.06.203.
     
  • Klapproth H, Rauterberg J, Shabli S, Silling S, Böttcher S, von Stebut E, Fabri M. Papulo-vesicular eruption and profound unilateral hearing loss in a 20-year-old man. J Dtsch Dermatol Ges. 2024 May;22(5):720-723. doi: 10.1111/ddg.15363. Epub 2024 Apr 6. PMID: 38581347.
     
  • Mammadov Y, Austin J, Shipowick T, Veldman K, Eming S, Szegedi A, Sprecher E, Conrad C. A European Roundtable "Addressing Under-Prioritized Skin Diseases: Policy Responses to High-Burden Conditions". J Invest Dermatol. 2024 Dec;144(12):2631-2633. doi: 10.1016/j.jid.2024.05.019. Epub 2024 Jul 16. PMID: 39023473.
     
  • Reiter L, Niehoff N, Weiland D, Helbig D, Eming SA, Krieg T, Etich J, Brachvogel B, Wiesner RJ, Knuever J. Mitochondrial DNA mutations attenuate Bleomycin-induced dermal fibrosis by inhibiting differentiation into myofibroblasts. Matrix Biol. 2024 Sep;132:72-86. doi: 10.1016/j.matbio.2024.07.002. Epub 2024 Jul 14. PMID: 39009171.
     
  • Willenborg S, Satzinger S, and Eming SA (2024). [Skin fibrosis : Novel insights in pathophysiology and treatment]. Dermatologie (Heidelb)75, 218-224. doi:10.1007/s00105-024-05299-7.
2023
  • Hadrian K, Musial G, Schonberg A, Georgiev T, Kuper C, Bock F, Jantsch J, Cursiefen C, Eming SA, and Hos D (2023). The role of the osmosensitive transcription factor NFAT5 in corneal edema resorption after injury. Exp Mol Med 55, 565-573. doi:10.1038/s12276-023-00954-w.
     
  • Injarabian L, Willenborg S, Welcker D, Sanin DE, Pasparakis M, Kashkar H, and Eming SA (2024). FADD- and RIPK3-Mediated Cell Death Ensures Clearance of Ly6C(high) Wound Macrophages from Damaged Tissue. J Invest Dermatol 144, 152-164 e157. doi:10.1016/j.jid.2023.06.203.
     
  • Riehl DR, Sharma A, Roewe J, Murke F, Ruppert C, Eming SA, Bopp T, Kleinert H, Radsak MP, Colucci G, Subramaniam S, Reinhardt C, Giebel B, Prinz I, Guenther A, Strand D, Gunzer M, Waisman A, Ward PA, Ruf W, Schafer K, and Bosmann M (2023). Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFbeta1 and IL-27. Proc Natl Acad Sci U S A 120, e2215421120. doi:10.1073/pnas.2215421120.
     
  • Satzinger S, Willenborg S, Ding X, Klose CSN, Radtke D, Voehringer D, and Eming SA (2023). Type 2 Immunity Regulates Dermal White Adipose Tissue Function. J Invest Dermatol 143, 2456-2467 e2455. doi:10.1016/j.jid.2023.05.017.

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