Center for Molecular Medicine Cologne

Prof. Dr. med. Thomas Benzing - Curriculum Vitae

Education and professional career

since 2015: Elected Member, American Society for Clinical Investigation
since 2010: Elected Member, National Academy of Sciences Leopoldina
since 2011: Appointed Advisor of the Alexander von Humboldt Foundation
since 2010: Director of the Center for Molecular Medicine Cologne
since 2008: Elected Honorary Member, Ludwig-Heilmeyer-Society
2008: Ernst Jung-Award for Medicine
since 2007: Co-Coordinator of the Cologne Cluster of Excellence on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne
since 2007: W3-Professor, Director and Chairman of Internal Medicine II, University of Cologne
2006 - 2007: W3-Professor, University Hospital Freiburg. Vice Chief Renal Division, University Hospital Freiburg
2006: Young Investigator Award of the American Society of Nephrology
2005 - 2007: Board Member, Center for Systems Biology Freiburg
since 2005: Advisory activity for the NIDDK and NIH, USA
2005: Honorary Fellow of the American Society of Nephrology
2005: Franz-Volhard-Award of the German Society of Nephrology
2004: Adalbert Buding Research Award of the German Society of Hypertension
2003 - 2005: Heisenberg Fellow of the German Research Foundation (DFG)
2002: Habilitation, PhD thesis, Venia Legendi for Internal Medicine
2000 - 2002: Fellowship in Nephrology (Prof. Walz), University Hospital Freiburg
1998 - 2000: Research Fellow in Nephrology, Harvard Medical School, Boston Research Fellowship of the German Research Foundation (DFG)
1996 - 1998: Postdoctoral Training (Prof. Busse) at the Institute for Cardiovascular Physiology, University Hospital Frankfurt

Selected publications

Ising C, Koeler S, Braehler S, Merkwirth C, Höhne M, Baris OR, Hagmann H, Kann M, Fabretti F, Dafinger C, Bloch W, Schermer B, Linkermann A, Brüning JC, Kurschat C, Müller RU, Wiesner R, Langer T, Benzing T, Brinkkötter PT. Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure. Embo Mol Med. 2015, 7, 275-287.

Benzing T. HALTing PKD progression - revival of blood pressure control. Nature Reviews Nephrol. 2015, 11, 129-131.

Mueller MM, Castells-Rocca L, Babu V, Ermolaeva MA, Müller RU, Frommolt P, Williams AB, Greiss S, Schneider JL, Benzing T, Schermer B, Schumacher B. DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage. Nat Cell Biol. 2014, 16, 1168-1179.

Kurschat CE, Müller RU, Franke M, Maintz D, Schermer B, Benzing T. An approach to cystic kidney disease: the clinician’s view. Nature Reviews Nephrol. 2014, 10, 687-699.

Borgal L, Rinschen MM, Dafinger C, Hoff S, Reinert MJ, Lamkemeyer T, Lienkamp SS, Benzing T, Schermer B. Casein kinase 1 alpha phsophorylates the Wnt regulator Jade-1 and modulates its activity. J Biol Chem. 2014, 289, 26344-26356.

Schurek EM, Völker LA, Tax J, Lamkemeyer T, Rinschen MM, Ungrue D, Kratz JE, Sirianant L, Kunzelmann K, Chalfie M, Schermer B, Benzing T, Höhne M. A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology domain protein podocin. J Biol Chem. 2014, 289, 11262-11271.

Hagmann H, Kuczkowski A, Ruehl M, Lamkemeyer T, Brodesser S, Horke S, Dryer S, Schermer B, Benzing T, Brinkkoetter PT. Breaking the chain at the membrane: paraoxonase 2 counteracts lipid peroxidation at the plasma membrane. FASEB J. 2014, 28, 1769-1779.

Hackl M, Burford JL, Villanueva K, Lam L, Susztak K, Schermer B, Benzing T, Peti-Peterdi J. Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags. Nature Med. 2013, 19, 1661-6.

Brinkkötter PT, Ising C, Benzing T. The role of the podocyte in albumin filtration. Nature Reviews Nephrol. 2013, 9, 328-336.

Gharbi H, Fabretti F, Bharill P, Rinschen MM, Brinkkötter PT, Frommolt P, Burst V, Schermer B, Benzing T, Müller RU. Loss of the Birt-Hogg-Dube gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner. Aging Cell. 2013, 12, 592-603.