Center for Molecular Medicine Cologne
NewsTelephone-BookDatenschutzerklärungImpressum
 

Summary of articles published by CMMC members in 2020

Original Articles and Reviews with CMMC affiliation listed in alphabetical order by the first author published in 2020.

  • Aguilar RC, Salmanton-Garcia J, Carney J, Boll B, Kochanek M, Jazmati N, Cornely OA, and Vehreschild M (2020). Clostridioides difficile infections in the intensive care unit: a monocentric cohort study. Infection48, 421-427. doi:10.1007/s15010-020-01413-8.
  • Albert MC, Brinkmann K, Pokrzywa W, Gunther SD, Kronke M, Hoppe T, and Kashkar H (2020). CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage. Cell Death Dis11, 740. doi:10.1038/s41419-020-02923-x.
  • Andersson EI, Bruck O, Braun T, Mannisto S, Saikko L, Lagstrom S, Ellonen P, Leppa S, Herling M, Kovanen PE, and Mustjoki S (2020). STAT3 Mutation Is Associated with STAT3 Activation in CD30(+) ALK(-) ALCL. Cancers (Basel)12. doi:10.3390/cancers12030702.
  • Armistead J, Hatzold J, van Roye A, Fahle E, and Hammerschmidt M (2020). Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase. J Cell Biol219. doi:10.1083/jcb.201905190.
  • Augustin M, Schommers P, Suarez I, Koehler P, Gruell H, Klein F, Maurer C, Langerbeins P, Priesner V, Schmidt-Hellerau K, Malin JJ, Stecher M, Jung N, Wiesmuller G, Meissner A, Zweigner J, Langebartels G, Kolibay F, Suarez V, Burst V, Valentin P, Schedler D, Cornely OA, Hallek M, Fatkenheuer G, Rybniker J, and Lehmann C (2020). Rapid response infrastructure for pandemic preparedness in a tertiary care hospital: lessons learned from the COVID-19 outbreak in Cologne, Germany, February to March 2020. Euro Surveill25. doi:10.2807/1560-7917.ES.2020.25.21.2000531.
  • Bacher P, Rosati E, Esser D, Martini GR, Saggau C, Schiminsky E, Dargvainiene J, Schroder I, Wieters I, Khodamoradi Y, Eberhardt F, Vehreschild M, Neb H, Sonntagbauer M, Conrad C, Tran F, Rosenstiel P, Markewitz R, Wandinger KP, Augustin M, Rybniker J, Kochanek M, Leypoldt F, Cornely OA, Koehler P, Franke A, and Scheffold A (2020). Low-Avidity CD4(+) T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19. Immunity53, 1258-1271 e1255. doi:10.1016/j.immuni.2020.11.016.
  • Balogh E, Chandler JC, Varga M, Tahoun M, Menyhard DK, Schay G, Goncalves T, Hamar R, Legradi R, Szekeres A, Gribouval O, Kleta R, Stanescu H, Bockenhauer D, Kerti A, Williams H, Kinsler V, Di WL, Curtis D, Kolatsi-Joannou M, Hammid H, Szocs A, Perczel K, Maka E, Toldi G, Sava F, Arrondel C, Kardos M, Fintha A, Hossain A, D'Arco F, Kaliakatsos M, Koeglmeier J, Mifsud W, Moosajee M, Faro A, Javorszky E, Rudas G, Saied MH, Marzouk S, Kelen K, Gotze J, Reusz G, Tulassay T, Dragon F, Mollet G, Motameny S, Thiele H, Dorval G, Nurnberg P, Perczel A, Szabo AJ, Long DA, Tomita K, Antignac C, Waters AM, and Tory K (2020). Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. Proc Natl Acad Sci U S A117, 15137-15147. doi:10.1073/pnas.2002328117.
  • Baraldo M, Geremia A, Pirazzini M, Nogara L, Solagna F, Turk C, Nolte H, Romanello V, Megighian A, Boncompagni S, Kruger M, Sandri M, and Blaauw B (2020). Skeletal muscle mTORC1 regulates neuromuscular junction stability. J Cachexia Sarcopenia Muscle11, 208-225. doi:10.1002/jcsm.12496.
  • Barbarino V, Henschke S, Blakemore SJ, Izquierdo E, Michalik M, Nickel N, Mollenkotte I, Vorholt D, Muller L, Brinker R, Fedorchenko O, Mikhael N, Seeger-Nukpezah T, Hallek M, and Pallasch CP (2020). Macrophage-Mediated Antibody Dependent Effector Function in Aggressive B-Cell Lymphoma Treatment is Enhanced by Ibrutinib via Inhibition of JAK2. Cancers (Basel)12. doi:10.3390/cancers12082303.
  • Barnes DR, Rookus MA, McGuffog L, Leslie G, Mooij TM, Dennis J, Mavaddat N, Adlard J, Ahmed M, Aittomaki K, Andrieu N, Andrulis IL, Arnold N, Arun BK, Azzollini J, Balmana J, Barkardottir RB, Barrowdale D, Benitez J, Berthet P, Bialkowska K, Blanco AM, Blok MJ, Bonanni B, Boonen SE, Borg A, Bozsik A, Bradbury AR, Brennan P, Brewer C, Brunet J, Buys SS, Caldes T, Caligo MA, Campbell I, Christensen LL, Chung WK, Claes KBM, Colas C, Collaborators GS, Collaborators E, Collonge-Rame MA, Cook J, Daly MB, Davidson R, de la Hoya M, de Putter R, Delnatte C, Devilee P, Diez O, Ding YC, Domchek SM, Dorfling CM, Dumont M, Eeles R, Ejlertsen B, Engel C, Evans DG, Faivre L, Foretova L, Fostira F, Friedlander M, Friedman E, Frost D, Ganz PA, Garber J, Gehrig A, Gerdes AM, Gesta P, Giraud S, Glendon G, Godwin AK, Goldgar DE, Gonzalez-Neira A, Greene MH, Gschwantler-Kaulich D, Hahnen E, Hamann U, Hanson H, Hentschel J, Hogervorst FBL, Hooning MJ, Horvath J, Hu C, Hulick PJ, Imyanitov EN, kConFab I, Investigators H, Investigators G, Isaacs C, Izatt L, Izquierdo A, Jakubowska A, James PA, Janavicius R, John EM, Joseph V, Karlan BY, Kast K, Koudijs M, Kruse TA, Kwong A, Laitman Y, Lasset C, Lazaro C, Lester J, Lesueur F, Liljegren A, Loud JT, Lubinski J, Mai PL, Manoukian S, Mari V, Mebirouk N, Meijers-Heijboer HEJ, Meindl A, Mensenkamp AR, Miller A, Montagna M, Mouret-Fourme E, Mukherjee S, Mulligan AM, Nathanson KL, Neuhausen SL, Nevanlinna H, Niederacher D, Nielsen FC, Nikitina-Zake L, Nogues C, Olah E, Olopade OI, Ong KR, O'Shaughnessy-Kirwan A, Osorio A, Ott CE, Papi L, Park SK, Parsons MT, Pedersen IS, Peissel B, Peixoto A, Peterlongo P, Pfeiler G, Phillips KA, Prajzendanc K, Pujana MA, Radice P, Ramser J, Ramus SJ, Rantala J, Rennert G, Risch HA, Robson M, Ronlund K, Salani R, Schuster H, Senter L, Shah PD, Sharma P, Side LE, Singer CF, Slavin TP, Soucy P, Southey MC, Spurdle AB, Steinemann D, Steinsnyder Z, Stoppa-Lyonnet D, Sutter C, Tan YY, Teixeira MR, Teo SH, Thull DL, Tischkowitz M, Tognazzo S, Toland AE, Trainer AH, Tung N, van Engelen K, van Rensburg EJ, Vega A, Vierstraete J, Wagner G, Walker L, Wang-Gohrke S, Wappenschmidt B, Weitzel JN, Yadav S, Yang X, Yannoukakos D, Zimbalatti D, Offit K, Thomassen M, Couch FJ, Schmutzler RK, Simard J, Easton DF, Chenevix-Trench G, Antoniou AC, Consortium of Investigators of Modifiers of B, and Brca (2020). Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants. Genet Med22, 1653-1666. doi:10.1038/s41436-020-0862-x.
  • Barthel R, Fedorchenko O, Velmans T, Rosen N, Nguyen PH, Reinart N, Florin A, Herling M, Hallek M, and Fingerle-Rowson G (2020). CD74 is dispensable for development of chronic lymphocytic leukemia inE mu-TCL1 transgenic mice. Leukemia & Lymphoma. doi:10.1080/10428194.2020.1791851.
  • Bastida MF, Perez-Gomez R, Trofka A, Zhu J, Rada-Iglesias A, Sheth R, Stadler HS, Mackem S, and Ros MA (2020). The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13. Proc Natl Acad Sci U S A117, 1090-1096. doi:10.1073/pnas.1919470117.
  • Batool M, Berghausen EM, Zierden M, Vantler M, Schermuly RT, Baldus S, Rosenkranz S, and Ten Freyhaus H (2020). The six-transmembrane protein Stamp2 ameliorates pulmonary vascular remodeling and pulmonary hypertension in mice. Basic Res Cardiol115, 68. doi:10.1007/s00395-020-00826-8.
  • Bayer EA, Stecky RC, Neal L, Katsamba PS, Ahlsen G, Balaji V, Hoppe T, Shapiro L, Oren-Suissa M, and Hobert O (2020). Ubiquitin-dependent regulation of a conserved DMRT protein controls sexually dimorphic synaptic connectivity and behavior. Elife9. doi:10.7554/eLife.59614.
  • Bayliss R, Wheeldon J, Caucheteux SM, Niessen CM, and Piguet V (2020). Identification of Host Trafficking Genes Required for HIV-1 Virological Synapse Formation in Dendritic Cells. J Virol94. doi:10.1128/JVI.01597-19.
  • Becker LL, Dafsari HS, Schallner J, Abdin D, Seifert M, Petit F, Smol T, Bok L, Rodan L, Krapels I, Spranger S, Weschke B, Johnson K, Straub V, Kaindl AM, Di Donato N, von der Hagen M, and Cirak S (2020). The clinical-phenotype continuum in DYNC1H1-related disorders-genomic profiling and proposal for a novel classification. J Hum Genet. doi:10.1038/s10038-020-0803-1.
  • Behnke V, and Langmann T (2020). IFN-beta signaling dampens microglia reactivity but does not prevent from light-induced retinal degeneration. Biochem Biophys Rep24, 100866. doi:10.1016/j.bbrep.2020.100866.
  • Bendell JC, Bischoff HG, Hwang J, Reinhardt HC, Zander T, Wang X, Hynes S, Pitou C, Campbell R, Iversen P, Farrington DL, Bell-McGuinn K, and Thomas M (2020). A phase 1 dose-escalation study of checkpoint kinase 1 (CHK1) inhibitor prexasertib in combination with p38 mitogen-activated protein kinase (p38 MAPK) inhibitor ralimetinib in patients with advanced or metastatic cancer. Invest New Drugs38, 1145-1155. doi:10.1007/s10637-019-00873-6.
  • Bender D, Kaczmarek AT, Kuester S, Burlina AB, and Schwarz G (2020). Oxygen and nitrite reduction by heme-deficient sulphite oxidase in a patient with mild sulphite oxidase deficiency. J Inherit Metab Dis. doi:10.1002/jimd.12216.
  • Benza RL, Corris PA, Klinger JR, Langleben D, Naeije R, Simonneau G, Ghofrani HA, Jansa P, Rosenkranz S, Scelsi L, Thenappan T, Raina A, Meier C, Busse D, and Hoeper MM (2020). Identifying potential parameters associated with response to switching from a PDE5i to riociguat in RESPITE. Int J Cardiol. doi:10.1016/j.ijcard.2020.05.044.
  • Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Kohler P, Kunstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dorr J, Drager A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuss J, Gluck A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Rocken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P, Network HCALB, and Deutsche C-OI (2020). Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19. Immunity53, 1296-1314 e1299. doi:10.1016/j.immuni.2020.11.017.
  • Berthold F, Faldum A, Ernst A, Boos J, Dilloo D, Eggert A, Fischer M, Fruhwald M, Henze G, Klingebiel T, Kratz C, Kremens B, Krug B, Leuschner I, Schmidt M, Schmidt R, Schumacher-Kuckelkorn R, von Schweinitz D, Schilling FH, Theissen J, Volland R, Hero B, and Simon T (2020). Extended induction chemotherapy does not improve the outcome for high-risk neuroblastoma patients: results of the randomized open-label GPOH trial NB2004-HR. Ann Oncol31, 422-429. doi:10.1016/j.annonc.2019.11.011.
  • Binz-Lotter J, Jungst C, Rinschen MM, Koehler S, Zentis P, Schauss A, Schermer B, Benzing T, and Hackl MJ (2020). Injured Podocytes Are Sensitized to Angiotensin II-Induced Calcium Signaling. J Am Soc Nephrol31, 532-542. doi:10.1681/ASN.2019020109.
  • Boedicker C, Hussong M, Grimm C, Dolgikh N, Meister MT, Enssle JC, Wanior M, Knapp S, Schweiger MR, and Fulda S (2020). Co-inhibition of BET proteins and PI3Kalpha triggers mitochondrial apoptosis in rhabdomyosarcoma cells. Oncogene39, 3837-3852. doi:10.1038/s41388-020-1229-0.
  • Boles NC, Fernandes M, Swigut T, Srinivasan R, Schiff L, Rada-Iglesias A, Wang Q, Saini JS, Kiehl T, Stern JH, Wysocka J, Blenkinsop TA, and Temple S (2020). Epigenomic and Transcriptomic Changes During Human RPE EMT in a Stem Cell Model of Epiretinal Membrane Pathogenesis and Prevention by Nicotinamide. Stem Cell Reports14, 631-647. doi:10.1016/j.stemcr.2020.03.009.
  • Braun F, Rinschen M, Buchner D, Bohl K, Plagmann I, Bachurski D, Richard Spath M, Antczak P, Gobel H, Klein C, Lackmann JW, Kretz O, Puelles VG, Wahba R, Hallek M, Schermer B, Benzing T, Huber TB, Beyer A, Stippel D, Kurschat CE, and Muller RU (2020). The proteomic landscape of small urinary extracellular vesicles during kidney transplantation. J Extracell Vesicles10(1), e12026. doi: 10.1002/jev2.12026
  • Budde BS, Aly MA, Mohamed MR, Bress A, Altmuller J, Motameny S, Kawalia A, Thiele H, Konrad K, Becker C, Toliat MR, Nurnberg G, Sayed EAF, Mohamed ES, Pfister M, and Nurnberg P (2020). Comprehensive molecular analysis of 61 Egyptian families with hereditary nonsyndromic hearing loss. Clin Genet. doi:10.1111/cge.13754.
  • Burgmaier K, Ariceta G, Bald M, Buescher AK, Burgmaier M, Erger F, Gessner M, Gokce I, Konig J, Kowalewska C, Massella L, Mastrangelo A, Mekahli D, Pape L, Patzer L, Potemkina A, Schalk G, Schild R, Shroff R, Szczepanska M, Taranta-Janusz K, Tkaczyk M, Weber LT, Wuhl E, Wurm D, Wygoda S, Zagozdzon I, Dotsch J, Oh J, Schaefer F, Liebau MC, and consortium AR (2020). Severe neurological outcomes after very early bilateral nephrectomies in patients with autosomal recessive polycystic kidney disease (ARPKD). Sci Rep10, 16025. doi:10.1038/s41598-020-71956-1.
  • Butt L, Unnersjo-Jess D, Hohne M, Edwards A, Binz-Lotter J, Reilly D, Hahnfeldt R, Ziegler V, Fremter K, Rinschen MM, Helmstadter M, Ebert LK, Castrop H, Hackl MJ, Walz G, Brinkkoetter PT, Liebau MC, Tory K, Hoyer PF, Beck BB, Brismar H, Blom H, Schermer B, and Benzing T (2020). A molecular mechanism explaining albuminuria in kidney disease. Nat Metab2, 461-474. doi:10.1038/s42255-020-0204-y.
  • Cartolano M, Abedpour N, Achter V, Yang TP, Ackermann S, Fischer M, and Peifer M (2020). CaMuS: simultaneous fitting and de novo imputation of cancer mutational signature. Sci Rep10, 19316. doi:10.1038/s41598-020-75753-8.
  • Casa V, Moronta Gines M, Gade Gusmao E, Slotman JA, Zirkel A, Josipovic N, Oole E, van IWFJ, Houtsmuller AB, Papantonis A, and Wendt KS (2020). Redundant and specific roles of cohesin STAG subunits in chromatin looping and transcriptional control. Genome Res30, 515-527. doi:10.1101/gr.253211.119.
  • Charmpi K, Guo T, Zhong Q, Wagner U, Sun R, Toussaint NC, Fritz CE, Yuan C, Chen H, Rupp NJ, Christiansen A, Rutishauser D, Ruschoff JH, Fankhauser C, Saba K, Poyet C, Hermanns T, Oehl K, Moore AL, Beisel C, Calzone L, Martignetti L, Zhang Q, Zhu Y, Martinez MR, Manica M, Haffner MC, Aebersold R, Wild PJ, and Beyer A (2020). Convergent network effects along the axis of gene expression during prostate cancer progression. Genome Biol21(1), 302. doi: 10.1186/s13059-020-02188-9
  • Clemente LP, Rabenau M, Tang S, Stanka J, Cors E, Stroh J, Culmsee C, and von Karstedt S (2020). Dynasore Blocks Ferroptosis through Combined Modulation of Iron Uptake and Inhibition of Mitochondrial Respiration. Cells9. doi:10.3390/cells9102259.
  • Cohen-Dvashi H, Zehner M, Ehrhardt S, Katz M, Elad N, Klein F, and Diskin R (2020). Structural Basis for a Convergent Immune Response against Ebola Virus. Cell Host Microbe27, 418-427 e414. doi:10.1016/j.chom.2020.01.007.
  • Cornely FB, Cornely OA, Salmanton-Garcia J, Koehler FC, Koehler P, Seifert H, Wingen-Heimann S, and Mellinghoff SC (2020). Attributable mortality of candidemia after introduction of echinocandins. Mycoses63, 1373-1381. doi:10.1111/myc.13177.
  • Cuesta-Mateos C, Fuentes P, Schrader A, Juarez-Sanchez R, Loscertales J, Mateu-Albero T, Vega-Piris L, Espartero-Santos M, Marcos-Jimenez A, Sanchez-Lopez BA, Perez-Garcia Y, Jungherz D, Oberbeck S, Wahnschaffe L, Kreutzman A, Andersson EI, Mustjoki S, Faber E, Urzainqui A, Fresno M, Stamatakis K, Alfranca A, Terron F, Herling M, Toribio ML, and Munoz-Calleja C (2020). CCR7 as a novel therapeutic target in t-cell PROLYMPHOCYTIC leukemia. Biomarker Research8. doi:Artn 54 10.1186/S40364-020-00234-Z.
  • Dafinger C, Mandel AM, Braun A, Goebel H, Burgmaier K, Massella L, Mastrangelo A, Doetsch J, Benzing T, Weimbs T, Schermer B & Liebau MC (2020) The carboxy-terminus of the human ARPKD protein fibrocystin can control STAT3 signalling by regulating SRC-activation. J. Cell. Mol. Med. 24, 14633–14638.
  • Ding C, Scicluna BP, Stroo I, Yang J, Roelofs JJ, de Boer OJ, de Vos AF, Nurnberg P, Revenko AS, Crosby J, Van't Veer C, and van der Poll T (2020). Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice. J Pathol250, 95-106. doi:10.1002/path.5354.
  • Ding X, Willenborg S, Bloch W, Wickstrom SA, Wagle P, Brodesser S, Roers A, Jais A, Bruning JC, Hall MN, Ruegg MA, and Eming SA (2020). Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation. J Allergy Clin Immunol145, 283-300 e288. doi:10.1016/j.jaci.2019.07.033.
  • Dinger K, Koningsbruggen-Rietschel SV, Dotsch J, and Alejandre Alcazar MA (2020). Identification of Critical Windows of Metabolic Programming of Metabolism and Lung Function in Male Offspring of Obese Dams. Clin Transl Sci. doi:10.1111/cts.12811.
  • DiToro D, Harbour SN, Bando JK, Benavides G, Witte S, Laufer VA, Moseley C, Singer JR, Frey B, Turner H, Bruning J, Darley-Usmar V, Gao M, Conover C, Hatton RD, Frank S, Colonna M, and Weaver CT (2020). Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity. Immunity52, 650-667 e610. doi:10.1016/j.immuni.2020.03.013.
  • Donkervoort S., Kutzner C.E., Hu Y., Lornage X., Rendu J., Stojkovic T., Baets J., Neuhaus S.B., Tanboon J., Maroofian R., Bolduc V., Mroczek M., Conijn S., Kuntz N.L., Töpf A., Monges S., Lubieniecki F., McCarty R.M., Chao K.R., Governali S., Böhm J., Boonyapisit K., Malfatti E., Sangruchi T., Horkayne-Szakaly I., Hedberg-Oldfors C., Efthymiou S., Noguchi S., Djeddi S., Iida A., di Rosa G., Fiorillo C., Salpietro V., Darin N., Fauré J., Houlden H., Oldfors A., Nishino I., de Ridder W., Straub V., Pokrzywa W., Laporte J., Foley A.R., Romero N.B., Ottenheijm C., Hoppe T.*, Bönnemann C.G.* (2020). Pathogenic Variants in the Myosin Chaperone UNC-45B Cause Progressive Myopathy with Eccentric Cores. Am. J. Hum. Genet. 107: 1078-1095.
  • Eberhardt KA, Meyer-Schwickerath C, Heger E, Knops E, Lehmann C, Rybniker J, Schommers P, Eichenauer DA, Kurth F, Ramharter M, Kaiser R, Holtick U, Klein F, Jung N, and Di Cristanziano V (2020). RNAemia Corresponds to Disease Severity and Antibody Response in Hospitalized COVID-19 Patients. Viruses12. doi:10.3390/v12091045.
  • El-Hindi K, Brachtendorf S, Hartel JC, Oertel S, Birod K, Trautmann S, Thomas D, Ulshofer T, Weigert A, Utermohlen O, Kronke M, and Grosch S (2020). Ceramide Synthase 5 Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis and Colon Carcinogenesis and Impairs T-Cell Activation. Cancers (Basel)12. doi:10.3390/cancers12071753.
  • Engstrom Ruud L, Pereira MMA, de Solis AJ, Fenselau H, and Bruning JC (2020). NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons. Nat Commun11, 442. doi:10.1038/s41467-020-14291-3.
  • Erger F, Norling D, Borchert D, Leenen E, Habbig S, Wiesener MS, Bartram MP, Wenzel A, Becker C, Toliat MR, Nurnberg P, Beck BB, and Altmuller J (2020). cfNOMe - A single assay for comprehensive epigenetic analyses of cell-free DNA. Genome Med12, 54. doi:10.1186/s13073-020-00750-5.
  • Escala-Garcia M, Abraham J, Andrulis IL, Anton-Culver H, Arndt V, Ashworth A, Auer PL, Auvinen P, Beckmann MW, Beesley J, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Blot W, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Brauch H, Brenner H, Brucker SY, Burwinkel B, Caldas C, Canzian F, Chang-Claude J, Chanock SJ, Chin SF, Clarke CL, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Dennis J, Devilee P, Dunn JA, Dunning AM, Dwek M, Earl HM, Eccles DM, Eliassen AH, Ellberg C, Evans DG, Fasching PA, Figueroa J, Flyger H, Gago-Dominguez M, Gapstur SM, Garcia-Closas M, Garcia-Saenz JA, Gaudet MM, George A, Giles GG, Goldgar DE, Gonzalez-Neira A, Grip M, Guenel P, Guo Q, Haiman CA, Hakansson N, Hamann U, Harrington PA, Hiller L, Hooning MJ, Hopper JL, Howell A, Huang CS, Huang G, Hunter DJ, Jakubowska A, John EM, Kaaks R, Kapoor PM, Keeman R, Kitahara CM, Koppert LB, Kraft P, Kristensen VN, Lambrechts D, Le Marchand L, Lejbkowicz F, Lindblom A, Lubinski J, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Martinez ME, Maurer T, Mavroudis D, Meindl A, Milne RL, Mulligan AM, Neuhausen SL, Nevanlinna H, Newman WG, Olshan AF, Olson JE, Olsson H, Orr N, Peterlongo P, Petridis C, Prentice RL, Presneau N, Punie K, Ramachandran D, Rennert G, Romero A, Sachchithananthan M, Saloustros E, Sawyer EJ, Schmutzler RK, Schwentner L, Scott C, Simard J, Sohn C, Southey MC, Swerdlow AJ, Tamimi RM, Tapper WJ, Teixeira MR, Terry MB, Thorne H, Tollenaar R, Tomlinson I, Troester MA, Truong T, Turnbull C, Vachon CM, van der Kolk LE, Wang Q, Winqvist R, Wolk A, Yang XR, Ziogas A, Pharoah PDP, Hall P, Wessels LFA, Chenevix-Trench G, Bader GD, Dork T, Easton DF, Canisius S, and Schmidt MK (2020). A network analysis to identify mediators of germline-driven differences in breast cancer prognosis. Nat Commun11, 312. doi:10.1038/s41467-019-14100-6.
  • Farooq M, Lindbaek L, Krogh N, Doganli C, Keller C, Monnich M, Goncalves AB, Sakthivel S, Mang Y, Fatima A, Andersen VS, Hussain MS, Eiberg H, Hansen L, Kjaer KW, Gopalakrishnan J, Pedersen LB, Mollgard K, Nielsen H, Baig SM, Tommerup N, Christensen ST, and Larsen LA (2020). RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis. Nat Commun 11, 5816. doi:10.1038/s41467-020-19658-0.
  • Fatima A, Irmak D, Noormohammadi A, Rinschen MM, Das A, Leidecker O, Schindler C, Sanchez-Gaya V, Wagle P, Pokrzywa W, Hoppe T, Rada-Iglesias A, and Vilchez D (2020). The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells. Commun Biol3, 262. doi:10.1038/s42003-020-0984-3.
  • Feng H, Gusev A, Pasaniuc B, Wu L, Long J, Abu-Full Z, Aittomaki K, Andrulis IL, Anton-Culver H, Antoniou AC, Arason A, Arndt V, Aronson KJ, Arun BK, Asseryanis E, Auer PL, Azzollini J, Balmana J, Barkardottir RB, Barnes DR, Barrowdale D, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bialkowska K, Blanco A, Blomqvist C, Boeckx B, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Borg A, Brauch H, Brenner H, Briceno I, Broeks A, Bruning T, Burwinkel B, Cai Q, Caldes T, Caligo MA, Campbell I, Canisius S, Campa D, Carter BD, Carter J, Castelao JE, Chang-Claude J, Chanock SJ, Christiansen H, Chung WK, Claes KBM, Clarke CL, Collaborators GS, Collaborators E, Collaborators G-Hs, Couch FJ, Cox A, Cross SS, Cybulski C, Czene K, Daly MB, de la Hoya M, De Leeneer K, Dennis J, Devilee P, Diez O, Domchek SM, Dork T, Dos-Santos-Silva I, Dunning AM, Dwek M, Eccles DM, Ejlertsen B, Ellberg C, Engel C, Eriksson M, Fasching PA, Fletcher O, Flyger H, Fostira F, Friedman E, Fritschi L, Frost D, Gabrielson M, Ganz PA, Gapstur SM, Garber J, Garcia-Closas M, Garcia-Saenz JA, Gaudet MM, Giles GG, Glendon G, Godwin AK, Goldberg MS, Goldgar DE, Gonzalez-Neira A, Greene MH, Gronwald J, Guenel P, Haiman CA, Hall P, Hamann U, Hake C, He W, Heyworth J, Hogervorst FBL, Hollestelle A, Hooning MJ, Hoover RN, Hopper JL, Huang G, Hulick PJ, Humphreys K, Imyanitov EN, Investigators A, Investigators H, Investigators B, Investigators O, Isaacs C, Jakimovska M, Jakubowska A, James P, Janavicius R, Jankowitz RC, John EM, Johnson N, Joseph V, Jung A, Karlan BY, Khusnutdinova E, Kiiski JI, Konstantopoulou I, Kristensen VN, Laitman Y, Lambrechts D, Lazaro C, Leroux D, Leslie G, Lester J, Lesueur F, Lindor N, Lindstrom S, Lo WY, Loud JT, Lubinski J, Makalic E, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Martens JWM, Martinez ME, Matricardi L, Maurer T, Mavroudis D, McGuffog L, Meindl A, Menon U, Michailidou K, Kapoor PM, Miller A, Montagna M, Moreno F, Moserle L, Mulligan AM, Muranen TA, Nathanson KL, Neuhausen SL, Nevanlinna H, Nevelsteen I, Nielsen FC, Nikitina-Zake L, Offit K, Olah E, Olopade OI, Olsson H, Osorio A, Papp J, Park-Simon TW, Parsons MT, Pedersen IS, Peixoto A, Peterlongo P, Peto J, Pharoah PDP, Phillips KA, Plaseska-Karanfilska D, Poppe B, Pradhan N, Prajzendanc K, Presneau N, Punie K, Pylkas K, Radice P, Rantala J, Rashid MU, Rennert G, Risch HA, Robson M, Romero A, Saloustros E, Sandler DP, Santos C, Sawyer EJ, Schmidt MK, Schmidt DF, Schmutzler RK, Schoemaker MJ, Scott RJ, Sharma P, Shu XO, Simard J, Singer CF, Skytte AB, Soucy P, Southey MC, Spinelli JJ, Spurdle AB, Stone J, Swerdlow AJ, Tapper WJ, Taylor JA, Teixeira MR, Terry MB, Teule A, Thomassen M, Thone K, Thull DL, Tischkowitz M, Toland AE, Tollenaar R, Torres D, Truong T, Tung N, Vachon CM, van Asperen CJ, van den Ouweland AMW, van Rensburg EJ, Vega A, Viel A, Vieiro-Balo P, Wang Q, Wappenschmidt B, Weinberg CR, Weitzel JN, Wendt C, Winqvist R, Yang XR, Yannoukakos D, Ziogas A, Milne RL, Easton DF, Chenevix-Trench G, Zheng W, Kraft P, and Jiang X (2020). Transcriptome-wide association study of breast cancer risk by estrogen-receptor status. Genet Epidemiol44, 442-468. doi:10.1002/gepi.22288.
  • Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Bruning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschop MH, and Muller TD (2020). The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation. Nat Commun11, 2306. doi:10.1038/s41467-020-16230-8.
  • Gazzi A, Fusco L, Orecchioni M, Ferrari S, Franzoni G, Yan JS, Rieckher M, Peng GT, Lucherelli MA, Vacchi IA, Chau NDQ, Criado A, Istif A, Mancino D, Dominguez A, Eckert H, Vazquez E, Da Ros T, Nicolussi P, Palermo V, Schumacher B, Cuniberti G, Mai YY, Clementi C, Pasquali M, Feng XL, Kostarelos K, Yilmazer A, Bedognetti D, Fadeel B, Prato M, Bianco A, and Delogu LG (2020). Graphene, other carbon nanomaterials and the immune system: toward nanoimmunity-by-design. Journal of Physics-Materials3. doi:Artn 034009 10.1088/2515-7639/Ab9317.
  • Gbel J, Engelhardt E, Pelzer P, Sakthivelu V, Jahn HM, Jevtic M, Folz-Donahue K, Kukat C, Schauss A, Frese CK, Giavalisco P, Ghanem A, Conzelmann KK, Motori E, and Bergami M (2020). Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling. Cell Metab31, 791-808 e798. doi:10.1016/j.cmet.2020.03.005.
  • Gebauer F, Kramer M, Bruns C, Schlosser HA, Thelen M, Lohneis P, Schroder W, Zander T, Alakus H, Buettner R, Loeser H, and Quaas A (2020). Lymphocyte activation gene-3 (LAG3) mRNA and protein expression on tumour infiltrating lymphocytes (TILs) in oesophageal adenocarcinoma. J Cancer Res Clin Oncol 146, 2319-2327. doi:10.1007/s00432-020-03295-7.
  • Gerbracht JV, Boehm V, Britto-Borges T, Kallabis S, Wiederstein JL, Ciriello S, Aschemeier DU, Kruger M, Frese CK, Altmuller J, Dieterich C, and Gehring NH (2020). CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex. Nucleic Acids Res48, 8626-8644. doi:10.1093/nar/gkaa564.
  • Grundmann F, Muller RU, Hoyer-Allo KJR, Spath MR, Passmann E, Becker I, Pfister R, Baldus S, Benzing T, and Burst V (2020). Dietary restriction for prevention of contrast-induced acute kidney injury in patients undergoing percutaneous coronary angiography: a randomized controlled trial. Sci Rep10, 5202. doi:10.1038/s41598-020-61895-2.
  • Gunther SD, Fritsch M, Seeger JM, Schiffmann LM, Snipas SJ, Coutelle M, Kufer TA, Higgins PG, Hornung V, Bernardini ML, Honing S, Kronke M, Salvesen GS, and Kashkar H (2020). Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide. Nat Microbiol5, 354-367. doi:10.1038/s41564-019-0620-5.
  • Hansel-Hertsch R, Simeone A, Shea A, Hui WWI, Zyner KG, Marsico G, Rueda OM, Bruna A, Martin A, Zhang X, Adhikari S, Tannahill D, Caldas C, and Balasubramanian S (2020). Landscape of G-quadruplex DNA structural regions in breast cancer. Nat Genet. doi:10.1038/s41588-020-0672-8.
  • Hanzlikova H, Prokhorova E, Krejcikova K, Cihlarova Z, Kalasova I, Kubovciak J, Sachova J, Hailstone R, Brazina J, Ghosh S, Cirak S, Gleeson JG, Ahel I, and Caldecott KW (2020). Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair. Nat Commun11, 3391. doi:10.1038/s41467-020-17069-9.
  • Hauke J, Harter P, Ernst C, Burges A, Schmidt S, Reuss A, Borde J, De Gregorio N, Dietrich D, El-Balat A, Kayali M, Gevensleben H, Hilpert F, Altmuller J, Heimbach A, Meier W, Schoemig-Markiefka B, Thiele H, Kimmig R, Nurnberg P, Kast K, Richters L, Sehouli J, Schmutzler RK, and Hahnen E (2020). Sensitivity and specificity of loss of heterozygosity analysis for the classification of rare germline variants in BRCA1/2: results of the observational AGO-TR1 study (NCT02222883). J Med Genet. doi:10.1136/jmedgenet-2020-107353.
  • Haumann S, Boix J, Knuever J, Bieling A, Vila Sanjurjo A, Elson JL, Blakely EL, Taylor RW, Riet N, Abken H, Kashkar H, Hornig-Do HT, and Wiesner RJ (2020). Mitochondrial DNA mutations induce mitochondrial biogenesis and increase the tumorigenic potential of Hodgkin and Reed-Sternberg cells. Carcinogenesis. doi:10.1093/carcin/bgaa032.
  • Hayashi T, Schrittenlocher S, Siebelmann S, Le VNH, Matthaei M, Franklin J, Bachmann B, and Cursiefen C (2020). Risk factors for endothelial cell loss after Descemet membrane endothelial keratoplasty (DMEK). Scientific Reports10. doi:10.1038/s41598-020-68023-0.
  • Heidepriem J, Krahling V, Dahlke C, Wolf T, Klein F, Addo MM, Becker S, and Loeffler FF (2020). Epitopes of Naturally Acquired and Vaccine-induced Anti-Ebola Virus Glycoprotein Antibodies in Single Amino Acid Resolution. Biotechnol J, e2000069. doi:10.1002/biot.202000069.
  • Heilig J, Dietmar HF, Brachvogel B, Paulsson M, Zaucke F, and Niehoff A (2020). Collagen IX deficiency leads to premature vascularization and ossification of murine femoral heads through an imbalance of pro- and antiangiogenic factors. Osteoarthritis Cartilage. doi:10.1016/j.joca.2020.03.015.
  • Hellweg CE, Shinde V, Srinivasan SP, Henry M, Rotshteyn T, Baumstark-Khan C, Schmitz C, Feles S, Spitta LF, Hemmersbach R, Hescheler J, and Sachinidis A (2020). Radiation Response of Murine Embryonic Stem Cells. Cells9. doi:Artn 1650 10.3390/Cells9071650.
  • Helmsauer K, Valieva M, Ali S, Chamorro Gonzalez R, Schöpflin R, Röefzaad C, Bei Y, Dorado Garcia H, Rodriguez-Fos E, Puiggròs M, Kasack K, Haase K, Keskeny C, Chen C, Kuschel LP, Euskirchen P, Heinrich V, Robson MI, Rosswog C, Toedling J, Szymansky A, Hertwig F, Fischer M, Torrents D, Eggert A, Schulte JH, Mundlos S, Henssen AG, Koche RP (2020). Enhancer hijacking determines intra- and extrachromosomal circular MYCN amplicon architecture in neuroblastoma. Nat Commun 11(1): 5823. doi: 10.1038/s41467-020-19452-y.
  • Herwig M, Kolijn D, Lodi M, Holper S, Kovacs A, Papp Z, Jaquet K, Haldenwang P, Dos Remedios C, Reusch PH, Mugge A, Kruger M, Fielitz J, Linke WA, and Hamdani N (2020). Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D. Front Physiol11, 240. doi:10.3389/fphys.2020.00240.
  • Hofsetz E, Demir F, Szczepanowska K, Kukat A, Kizhakkedathu JN, Trifunovic A, and Huesgen PF (2020). The Mouse Heart Mitochondria N Terminome Provides Insights into ClpXP-Mediated Proteolysis. Mol Cell Proteomics19, 1330-1345. doi:10.1074/mcp.RA120.002082.
  • Hohmann C, Pfister R, Mollenhauer M, Adler C, Kozlowski J, Wodarz A, Drebber U, Wippermann J, and Michels G (2020). Inflammatory cell infiltration in left atrial appendageal tissues of patients with atrial fibrillation and sinus rhythm. Sci Rep10, 1685. doi:10.1038/s41598-020-58797-8.
  • Holscher C, Grab J, Holscher A, Muller AL, Schafer SC, and Rybniker J (2020). Chemical p38 MAP kinase inhibition constrains tissue inflammation and improves antibiotic activity in Mycobacterium tuberculosis-infected mice. Sci Rep10, 13629. doi:10.1038/s41598-020-70184-x.
  • Hombach AA, Geumann U, Gunther C, Hermann FG, and Abken H (2020). IL7-IL12 Engineered Mesenchymal Stem Cells (MSCs) Improve A CAR T Cell Attack Against Colorectal Cancer Cells. Cells9. doi:10.3390/cells9040873.
  • Horn M, Denzel SI, Srinivasan B, Allmeroth K, Schiffer I, Karthikaisamy V, Miethe S, Breuer P, Antebi A, and Denzel MS (2020). Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response. iScience23, 100887. doi:10.1016/j.isci.2020.100887.
  • Hos NJ, Fischer J, Hos D, Hejazi Z, Calabrese C, Ganesan R, Murthy AMV, Rybniker J, Kumar S, Kronke M, and Robinson N (2020). TRIM21 Is Targeted for Chaperone-Mediated Autophagy during Salmonella Typhimurium Infection. J Immunol205, 2456-2467. doi:10.4049/jimmunol.2000048.
  • Imhof T, Korkmaz Y, Koch M, Sengle G, and Schiavinato A (2020). EMILIN proteins are novel extracellular constituents of the dentin-pulp complex. Sci Rep10, 15320. doi:10.1038/s41598-020-72123-2.
  • Imhof T, Rosenblatt K, Pryymachuk G, Weiland D, Noetzel N, Deschner J, Baris OR, Kimoloi S, Koch M, Wiesner RJ, and Korkmaz Y (2020). Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor. Sci Rep10, 22037. doi:10.1038/s41598-020-77954-7.
  • Jais A, Paeger L, Sotelo-Hitschfeld T, Bremser S, Prinzensteiner M, Klemm P, Mykytiuk V, Widdershooven PJM, Vesting AJ, Grzelka K, Minere M, Cremer AL, Xu J, Korotkova T, Lowell BB, Zeilhofer HU, Backes H, Fenselau H, Wunderlich FT, Kloppenburg P, and Bruning JC (2020). PNOC(ARC) Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding. Neuron. doi:10.1016/j.neuron.2020.03.022.
  • Jakobs F, Drost R, Kron A, Heinen J, Hallek M, Reinhardt HC, Zander T, and Kron F (2020). Economic Impact of the Introduction of Outpatient Medical Specialist Care (ASV) of Gastrointestinal Cancer Patients from a German Hospital Management Perspective. Oncol Res Treat43, 498-505. doi:10.1159/000509618.
  • Jiang H, Gallet S, Klemm P, Scholl P, Folz-Donahue K, Altmuller J, Alber J, Heilinger C, Kukat C, Loyens A, Muller-Fielitz H, Sundaram S, Schwaninger M, Prevot V, and Bruning JC (2020). MCH Neurons Regulate Permeability of the Median Eminence Barrier. Neuron. doi:10.1016/j.neuron.2020.04.020.
  • Jiao H, Wachsmuth L, Kumari S, Schwarzer R, Lin J, Eren RO, Fisher A, Lane R, Young GR, Kassiotis G, Kaiser WJ, and Pasparakis M (2020). Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation. Nature580, 391-395. doi:10.1038/s41586-020-2129-8.
  • Johnsen M, Kubacki T, Yeroslaviz A, Spath MR, Morsdorf J, Gobel H, Bohl K, Ignarski M, Meharg C, Habermann B, Altmuller J, Beyer A, Benzing T, Schermer B, Burst V, and Muller RU (2020). The Integrated RNA Landscape of Renal Preconditioning against Ischemia-Reperfusion Injury. J Am Soc Nephrol31 (4), 716-30. doi: 10.1681/ASN.2019050534.
  • Kakanj P, Eming SA, Partridge L, and Leptin M (2020). Long-term in vivo imaging of Drosophila larvae. Nat Protoc15, 1158-1187. doi:10.1038/s41596-019-0282-z.
  • Kallabis S, Abraham L, Muller S, Dzialas V, Turk C, Wiederstein JL, Bock T, Nolte H, Nogara L, Blaauw B, Braun T, and Kruger M (2020). High-throughput proteomics fiber typing (ProFiT) for comprehensive characterization of single skeletal muscle fibers. Skelet Muscle10, 7. doi:10.1186/s13395-020-00226-5.
  • Kaltenecker D, Spirk K, Ruge F, Grebien F, Herling M, Rupprecht A, Kenner L, Pohl EE, Mueller KM, and Moriggl R (2020). STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue. Mol Metab, 101026. doi:10.1016/j.molmet.2020.101026.
  • Kamrad S, Grossbach J, Rodriguez-Lopez M, Mulleder M, Townsend S, Cappelletti V, Stojanovski G, Correia-Melo C, Picotti P, Beyer A, Ralser M, and Bahler J (2020). Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance. Mol Syst Biol16 (4), e9270. doi: 10.15252/msb.20199270.
  • Karsak M, Glebov K, Scheffold M, Bajaj T, Kawalia A, Karaca I, Rading S, Kornhuber J, Peters O, Diez-Fairen M, Frolich L, Hull M, Wiltfang J, Scherer M, Riedel-Heller S, Schneider A, Heneka MT, Fliessbach K, Sharaf A, Thiele H, Lennarz M, Jessen F, Maier W, Kubisch C, Ignatova Z, Nurnberg P, Pastor P, Walter J, and Ramirez A (2020). A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2. Hum Mutat41, 169-181. doi:10.1002/humu.23904.
  • Kaufeld J, Brinkkoetter PT, Schreiber A, Jabs WJ, Bieringer M, Bruck H, Menne J, and Volker LA (2020). Caplacizumab: frequent local skin reactions. Annals of Hematology. doi:10.1007/s00277-020-04260-7.
  • Keller N, Mendoza-Ferreira N, Maroofian R, Chelban V, Khalil Y, Mills PB, Boostani R, Torbati PN, Karimiani EG, Thiele H, Houlden H, Wirth B, and Karakaya M (2020). Hereditary polyneuropathy with optic atrophy due to PDXK variant leading to impaired Vitamin B6 metabolism. Neuromuscul Disord30, 583-589. doi:10.1016/j.nmd.2020.04.004.
  • Kew C, Huang W, Fischer J, Ganesan R, Robinson N, and Antebi A (2020). Evolutionarily conserved regulation of immunity by the splicing factor RNP-6/PUF60. Elife9. doi:10.7554/eLife.57591.
  • Khan AS, and Langmann T (2020). Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration. J Neuroinflammation17, 327. doi:10.1186/s12974-020-01999-8.
  • Kim CS, Ding XL, Allmeroth K, Biggs LC, Kolenc OI, L'Hoest N, Chacon-Martinez CA, Edlich-Muth C, Giavalisco P, Quinn KP, Denzel MS, Eming SA, and Wickstrom SA (2020). Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle. Cell Metabolism32, 629-+. doi:10.1016/j.cmet.2020.08.011.
  • Klein S, Quaas A, Noh KW, Cartolano M, Abedpour N, Mauch C, Quantius J, Reinhardt HC, Buettner R, Peifer M, and Helbig D (2020). Integrative Analysis of Pleomorphic Dermal Sarcomas Reveals Fibroblastic Differentiation and Susceptibility to Immunotherapy. Clin Cancer Res 26, 5638-5645. doi:10.1158/1078-0432.CCR-20-1899.
  • Koch M, Reinartz S, Saggau J, Knittel G, Rosen N, Fedorchenko O, Thelen L, Barthel R, Reinart N, Seeger-Nukpezah T, Reinhardt HC, Hallek M, and Nguyen PH (2020). Meta-Analysis Reveals Significant Sex Differences in Chronic Lymphocytic Leukemia Progression in the Emicro-TCL1 Transgenic Mouse Model. Cancers (Basel)12. doi:10.3390/cancers12071980.
  • Koche RP, Rodriguez-Fos E, Helmsauer K, Burkert M, MacArthur IC, Maag J, Chamorro R, Munoz-Perez N, Puiggros M, Dorado Garcia H, Bei Y, Roefzaad C, Bardinet V, Szymansky A, Winkler A, Thole T, Timme N, Kasack K, Fuchs S, Klironomos F, Thiessen N, Blanc E, Schmelz K, Kunkele A, Hundsdorfer P, Rosswog C, Theissen J, Beule D, Deubzer H, Sauer S, Toedling J, Fischer M, Hertwig F, Schwarz RF, Eggert A, Torrents D, Schulte JH, and Henssen AG (2020). Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma. Nat Genet52, 29-34. doi:10.1038/s41588-019-0547-z.
  • Koehler S, Kuczkowski A, Kuehne L, Jungst C, Hoehne M, Grahammer F, Eddy S, Kretzler M, Beck BB, Hohfeld J, Schermer B, Benzing T, Brinkkoetter PT, and Rinschen MM (2020). Proteome Analysis of Isolated Podocytes Reveals Stress Responses in Glomerular Sclerosis. Journal of the American Society of Nephrology31, 544-559. doi:10.1681/Asn.2019030312.
  • Kohler A, Morgelin M, Gebauer JM, Ocal S, Imhof T, Koch M, Nagata K, Paulsson M, Zaucke F, Baumann U, and Sengle G (2020). New specific HSP47 functions in collagen subfamily chaperoning. FASEB J. doi:10.1096/fj.202000570R.
  • Kohlhas V, Hallek M, and Nguyen PH (2020). Constitutive activation of Lyn kinase enhances BCR responsiveness, but not the development of CLL in Emicro-TCL1 mice. Blood Adv 4, 6106-6116. doi:10.1182/bloodadvances.2020002584.
  • Kok RNU, Hebert L, Huelsz-Prince G, Goos YJ, Zheng X, Bozek K, Stephens GJ, Tans SJ, and van Zon JS (2020). OrganoidTracker: Efficient cell tracking using machine learning and manual error correction. PLoS One15, e0240802. doi:10.1371/journal.pone.0240802.
  • Kolbuc M, Lessmeier L, Salamon-Slowinska D, Malecka I, Pawlaczyk K, Walkowiak J, Wysocki J, Beck BB, and Zaniew M (2020). Hypomagnesemia is underestimated in children with HNF1B mutations. Pediatric Nephrology. doi:10.1007/s00467-020-04576-6.
  • Kong YW, Dreaden EC, Morandell S, Zhou W, Dhara SS, Sriram G, Lam FC, Patterson JC, Quadir M, Dinh A, Shopsowitz KE, Varmeh S, Yilmaz OH, Lippard SJ, Reinhardt HC, Hemann MT, Hammond PT, and Yaffe MB (2020). Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints. Nat Commun11, 4124. doi:10.1038/s41467-020-17958-z.
  • Kramer I, Hooning MJ, Mavaddat N, Hauptmann M, Keeman R, Steyerberg EW, Giardiello D, Antoniou AC, Pharoah PDP, Canisius S, Abu-Ful Z, Andrulis IL, Anton-Culver H, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Bremer M, Brucker SY, Burwinkel B, Castelao JE, Chan TL, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Choi JY, Clarke CL, Collaborators N, Collee JM, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dork T, Dos-Santos-Silva I, Dunning AM, Dwek M, Eccles DM, Evans DG, Fasching PA, Flyger H, Gago-Dominguez M, Garcia-Closas M, Garcia-Saenz JA, Giles GG, Goldgar DE, Gonzalez-Neira A, Haiman CA, Hakansson N, Hamann U, Hartman M, Heemskerk-Gerritsen BAM, Hollestelle A, Hopper JL, Hou MF, Howell A, Investigators A, kConFab I, Ito H, Jakimovska M, Jakubowska A, Janni W, John EM, Jung A, Kang D, Kets CM, Khusnutdinova E, Ko YD, Kristensen VN, Kurian AW, Kwong A, Lambrechts D, Le Marchand L, Li J, Lindblom A, Lubinski J, Mannermaa A, Manoochehri M, Margolin S, Matsuo K, Mavroudis D, Meindl A, Milne RL, Mulligan AM, Muranen TA, Neuhausen SL, Nevanlinna H, Newman WG, Olshan AF, Olson JE, Olsson H, Park-Simon TW, Peto J, Petridis C, Plaseska-Karanfilska D, Presneau N, Pylkas K, Radice P, Rennert G, Romero A, Roylance R, Saloustros E, Sawyer EJ, Schmutzler RK, Schwentner L, Scott C, See MH, Shah M, Shen CY, Shu XO, Siesling S, Slager S, Sohn C, Southey MC, Spinelli JJ, Stone J, Tapper WJ, Tengstrom M, Teo SH, Terry MB, Tollenaar R, Tomlinson I, Troester MA, Vachon CM, van Ongeval C, van Veen EM, Winqvist R, Wolk A, Zheng W, Ziogas A, Easton DF, Hall P, and Schmidt MK (2020). Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk. Am J Hum Genet107, 837-848. doi:10.1016/j.ajhg.2020.09.001.
  • Kramer M, Plum PS, Velazquez Camacho O, Folz-Donahue K, Thelen M, Garcia-Marquez I, Wolwer C, Busker S, Wittig J, Franitza M, Altmuller J, Loser H, Schlosser H, Buttner R, Schroder W, Bruns CJ, Alakus H, Quaas A, Chon SH, and Hillmer AM (2020). Cell type-specific transcriptomics of esophageal adenocarcinoma as a scalable alternative for single cell transcriptomics. Mol Oncol14, 1170-1184. doi:10.1002/1878-0261.12680.
  • Kreer C, Doring M, Lehnen N, Ercanoglu MS, Gieselmann L, Luca D, Jain K, Schommers P, Pfeifer N, and Klein F (2020). openPrimeR for multiplex amplification of highly diverse templates. J Immunol Methods480, 112752. doi:10.1016/j.jim.2020.112752.
  • Kreer C, Zehner M, Weber T, Ercanoglu MS, Gieselmann L, Rohde C, Halwe S, Korenkov M, Schommers P, Vanshylla K, Di Cristanziano V, Janicki H, Brinker R, Ashurov A, Krahling V, Kupke A, Cohen-Dvashi H, Koch M, Eckert JM, Lederer S, Pfeifer N, Wolf T, Vehreschild MJGT, Wendtner C, Diskin R, Gruell H, Becker S, and Klein F (2020). Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients. Cell182, 843-+. doi:10.1016/j.cell.2020.06.044.
  • Kretschmer T, Schulze-Edinghausen M, Turnwald EM, Janoschek R, Bae-Gartz I, Zentis P, Handwerk M, Wohlfarth M, Schauss A, Hucklenbruch-Rother E, Dotsch J, and Appel S (2020). Effect of Maternal Obesity in Mice on IL-6 Levels and Placental Endothelial Cell Homeostasis. Nutrients12. doi:10.3390/nu12020296.
  • Kretschmer T, Turnwald EM, Janoschek R, Zentis P, Bae-Gartz I, van Beers T, Handwerk M, Wohlfarth M, Ghilav M, Bloch W, Hucklenbruch-Rother E, Dotsch J, and Appel S (2020). Maternal high fat diet-induced obesity affects trophoblast differentiation and placental function in mice. Biol Reprod. doi:10.1093/biolre/ioaa166.
  • Kreuzer KA, Furman RR, Stilgenbauer S, Dubowy RL, Kim Y, Munugalavadla V, Lilienweiss E, Reinhardt HC, Cramer P, Eichhorst B, Hillmen P, O'Brien SM, Pettitt AR, and Hallek M (2020). The impact of complex karyotype on the overall survival of patients with relapsed chronic lymphocytic leukemia treated with idelalisib plus rituximab. Leukemia 34, 296-300. doi:10.1038/s41375-019-0533-6.
  • Kruger SF, Cadilha BL, von Bergwelt-Baildon M, Endres S, and Kobold S (2020). Challenges in Clinical Trial Design for T Cell-Based Cancer Immunotherapy. Clin Pharmacol Ther107, 47-49. doi:10.1002/cpt.1659.
  • Kuiper-Makris C, Zanetti D, Vohlen C, Fahle L, Muller M, Odenthal M, Felderhoff-Muser U, Dotsch J, and Alejandre Alcazar MA (2020). Mendelian randomization and experimental IUGR reveal the adverse effect of low birth weight on lung structure and function. Sci Rep10, 22395. doi:10.1038/s41598-020-79245-7.
  • Lalaoui N, Boyden SE, Oda H, Wood GM, Stone DL, Chau D, Liu L, Stoffels M, Kratina T, Lawlor KE, Zaal KJM, Hoffmann PM, Etemadi N, Shield-Artin K, Biben C, Tsai WL, Blake MD, Kuehn HS, Yang D, Anderton H, Silke N, Wachsmuth L, Zheng L, Moura NS, Beck DB, Gutierrez-Cruz G, Ombrello AK, Pinto-Patarroyo GP, Kueh AJ, Herold MJ, Hall C, Wang H, Chae JJ, Dmitrieva NI, McKenzie M, Light A, Barham BK, Jones A, Romeo TM, Zhou Q, Aksentijevich I, Mullikin JC, Gross AJ, Shum AK, Hawkins ED, Masters SL, Lenardo MJ, Boehm M, Rosenzweig SD, Pasparakis M, Voss AK, Gadina M, Kastner DL, and Silke J (2020). Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease. Nature577, 103-108. doi:10.1038/s41586-019-1828-5.
  • Laurien L, Nagata M, Schunke H, Delanghe T, Wiederstein JL, Kumari S, Schwarzer R, Corona T, Kruger M, Bertrand MJM, Kondylis V, and Pasparakis M (2020). Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation. Nat Commun11, 1747. doi:10.1038/s41467-020-15466-8.
  • Le VNH, Hos D, Hou Y, Witt M, Barkovskiy M, Bock F, and Cursiefen C (2020). VEGF TrapR1R2 Suspended in the Semifluorinated Alkane F6H8 Inhibits Inflammatory Corneal Hem- and Lymphangiogenesis. Transl Vis Sci Technol9, 15. doi:10.1167/tvst.9.11.15.
  • Le VNH, Hou Y, Bock F, and Cursiefen C (2020). Supplemental Anti Vegf A-Therapy Prevents Rebound Neovascularisation After Fine Needle Diathermy Treatment to Regress Pathological Corneal (LYMPH)Angiogenesis. Sci Rep10, 3908. doi:10.1038/s41598-020-60705-z.
  • Lenders M, Nordbeck P, Kurschat C, Karabul N, Kaufeld J, Hennermann JB, Patten M, Cybulla M, Muntze J, Uceyler N, Liu D, Das AM, Sommer C, Pogoda C, Reiermann S, Duning T, Gaedeke J, Stumpfe K, Blaschke D, Brand SM, Mann WA, Kampmann C, Muschol N, Canaan-Kuhl S, and Brand E (2020). Treatment of Fabry's Disease With Migalastat: Outcome From a Prospective Observational Multicenter Study (FAMOUS). Clin Pharmacol Ther108, 326-337. doi:10.1002/cpt.1832.
  • Lessel I, Chen MJ, Luttgen S, Arndt F, Fuchs S, Meien S, Thiele H, Jones JR, Shaw BR, Crossman DK, Nurnberg P, Korf BR, Kubisch C, and Lessel D (2020). Two novel cases further expand the phenotype of TOR1AIP1-associated nuclear envelopathies. Hum Genet139, 483-498. doi:10.1007/s00439-019-02105-6.
  • Li H, Terry MB, Antoniou AC, Phillips KA, Kast K, Mooij TM, Engel C, Nogues C, Stoppa-Lyonnet D, Lasset C, Berthet P, Mari V, Caron O, study G, Barrowdale D, Frost D, Brewer C, Evans DG, Izatt L, Side L, Walker L, Tischkowitz M, Rogers MT, Porteous ME, Snape K, study E, Meijers-Heijboer HEJ, Gille JJP, Blok MJ, Hoogerbrugge N, Investigators H, Daly MB, Andrulis IL, Buys SS, John EM, McLachlan SA, Friedlander M, kConFab I, Tan YY, Osorio A, Caldes T, Jakubowska A, Simard J, Singer CF, Olah E, Navratilova M, Foretova L, Gerdes AM, Roos-Blom MJ, Arver B, Olsson H, Schmutzler RK, Hopper JL, Milne RL, Easton DF, Van Leeuwen FE, Rookus MA, Andrieu N, and Goldgar DE (2020). Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium. Cancer Epidemiol Biomarkers Prev29, 368-378. doi:10.1158/1055-9965.EPI-19-0546.
  • Li P, Fleischhauer L, Nicolae C, Prein C, Farkas Z, Saller MM, Prall WC, Wagener R, Heilig J, Niehoff A, Clausen-Schaumann H, Alberton P, and Aszodi A (2020). Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis. Int J Mol Sci21. doi:10.3390/ijms21020666.
  • Linnemannstons K, Witte L, Karuna MP, Kittel JC, Danieli A, Muller D, Nitsch L, Honemann-Capito M, Grawe F, Wodarz A, and Gross JC (2020). Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium. Development147. doi:10.1242/dev.185421.
  • Litzenburger T, Huber EK, Dinger K, Wilke R, Vohlen C, Selle J, Kadah M, Persigehl T, Heneweer C, Dotsch J, and Alcazar MAA (2020). Maternal high-fat diet induces long-term obesity with sex-dependent metabolic programming of adipocyte differentiation, hypertrophy and dysfunction in he offspring. Clinical Science134, 921-939. doi:10.1042/Cs20191229.
  • Liu J, Prager-van der Smissen WJC, Collee JM, Bolla MK, Wang Q, Michailidou K, Dennis J, Ahearn TU, Aittomaki K, Ambrosone CB, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Arnold N, Aronson KJ, Augustinsson A, Auvinen P, Becher H, Beckmann MW, Behrens S, Bermisheva M, Bernstein L, Bogdanova NV, Bogdanova-Markov N, Bojesen SE, Brauch H, Brenner H, Briceno I, Brucker SY, Bruning T, Burwinkel B, Cai Q, Cai H, Campa D, Canzian F, Castelao JE, Chang-Claude J, Chanock SJ, Choi JY, Christiaens M, Clarke CL, Collaborators N, Couch FJ, Czene K, Daly MB, Devilee P, Dos-Santos-Silva I, Dwek M, Eccles DM, Eliassen AH, Fasching PA, Figueroa J, Flyger H, Fritschi L, Gago-Dominguez M, Gapstur SM, Garcia-Closas M, Garcia-Saenz JA, Gaudet MM, Giles GG, Goldberg MS, Goldgar DE, Guenel P, Haiman CA, Hakansson N, Hall P, Harrington PA, Hart SN, Hartman M, Hillemanns P, Hopper JL, Hou MF, Hunter DJ, Huo D, Investigators A, Ito H, Iwasaki M, Jakimovska M, Jakubowska A, John EM, Kaaks R, Kang D, Keeman R, Khusnutdinova E, Kim SW, Kraft P, Kristensen VN, Kurian AW, Le Marchand L, Li J, Lindblom A, Lophatananon A, Luben RN, Lubinski J, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Mariapun S, Matsuo K, Maurer T, Mavroudis D, Meindl A, Menon U, Milne RL, Muir K, Mulligan AM, Neuhausen SL, Nevanlinna H, Offit K, Olopade OI, Olson JE, Olsson H, Orr N, Park SK, Peterlongo P, Peto J, Plaseska-Karanfilska D, Presneau N, Rack B, Rau-Murthy R, Rennert G, Rennert HS, Rhenius V, Romero A, Ruebner M, Saloustros E, Schmutzler RK, Schneeweiss A, Scott C, Shah M, Shen CY, Shu XO, Simard J, Sohn C, Southey MC, Spinelli JJ, Tamimi RM, Tapper WJ, Teo SH, Terry MB, Torres D, Truong T, Untch M, Vachon CM, van Asperen CJ, Wolk A, Yamaji T, Zheng W, Ziogas A, Ziv E, Torres-Mejia G, Dork T, Swerdlow AJ, Hamann U, Schmidt MK, Dunning AM, Pharoah PDP, Easton DF, Hooning MJ, Martens JWM, and Hollestelle A (2020). Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk. Sci Rep10, 9688. doi:10.1038/s41598-020-65665-y.
  • Loescher C M, Breitkreuz M, Li Y, Nickel A, Unger A, Dietl A, Schmidt A, Mohamed B A, Kötter S, Schmitt J P, Krüger, M, Krüger M, Toischer K, Maack C, Leichert L I, Hamdani N, Linke W A (2020). Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx). Proc Natl Acad Sci USA 117(39), 24545-56.
  • Lopes AFC, Bozek K, Herholz M, Trifunovic A, Rieckher M, and Schumacher B (2020). A C. elegans model for neurodegeneration in Cockayne syndrome. Nucleic Acids Res 48, 10973-10985. doi:10.1093/nar/gkaa795.
  • Lucendo-Villarin B, Nell P, Hellwig B, Filis P, Feuerborn D, O'Shaughnessy PJ, Godoy P, Rahnenfuhrer J, Hengstler JG, Cherianidou A, Sachinidis A, Fowler PA, and Hay DC (2020). Genome-wide expression changes induced by bisphenol A, F and S in human stem cell derived hepatocyte-like cells. EXCLI J19, 1459-1476. doi:10.17179/excli2020-2934.
  • Luers JC, Rokohl AC, Loreck N, Wawer Matos PA, Augustin M, Dewald F, Klein F, Lehmann C, and Heindl LM (2020). Olfactory and Gustatory Dysfunction in Coronavirus Disease 2019 (COVID-19). Clin Infect Dis71, 2262-2264. doi:10.1093/cid/ciaa525.
  • Mathews TJ, Stevenson LM, Pickhardt PC, Murphy CA, Nisbet RM, Antczak P, Garcia-Reyero N, and Gergs A (2020). The Effect of Dietary Exposure to Coal Ash Contaminants within Food Ration on Growth and Reproduction in Daphnia magna. Environ Toxicol Chem. doi:10.1002/etc.4819.
  • Matin M, Morgelin M, Stetefeld J, Schermer B, Brinkkoetter PT, Benzing T, Koch M, and Hagmann H (2020). Affinity-Enhanced Multimeric VEGF (Vascular Endothelial Growth Factor) and PlGF (Placental Growth Factor) Variants for Specific Adsorption of sFlt-1 to Restore Angiogenic Balance in Preeclampsia. Hypertension76, 1176-1184. doi:10.1161/HYPERTENSIONAHA.120.14974.
  • Maurer B, Nivarthi H, Wingelhofer B, Pham HTT, Schlederer M, Suske T, Grausenburger R, Schiefer AI, Prchal-Murphy M, Chen D, Winkler S, Merkel O, Kornauth C, Hofbauer M, Hochgatterer B, Hoermann G, Hoelbl-Kovacic A, Prochazkova J, Lobello C, Cumaraswamy AA, Latzka J, Kitzwogerer M, Chott A, Janikova A, Pospisilova S, Loizou JI, Kubicek S, Valent P, Kolbe T, Grebien F, Kenner L, Gunning PT, Kralovics R, Herling M, Muller M, Rulicke T, Sexl V, and Moriggl R (2020). High activation of STAT5A drives peripheral T-cell lymphoma and leukemia. Haematologica105, 435-447. doi:10.3324/haematol.2019.216986.
  • Mavaddat N, Antoniou AC, Mooij TM, Hooning MJ, Heemskerk-Gerritsen BA, Genepso, Nogues C, Gauthier-Villars M, Caron O, Gesta P, Pujol P, Lortholary A, Embrace, Barrowdale D, Frost D, Evans DG, Izatt L, Adlard J, Eeles R, Brewer C, Tischkowitz M, Henderson A, Cook J, Eccles D, Hebon, van Engelen K, Mourits MJE, Ausems M, Koppert LB, Hopper JL, John EM, Chung WK, Andrulis IL, Daly MB, Buys SS, kConFab I, Benitez J, Caldes T, Jakubowska A, Simard J, Singer CF, Tan Y, Olah E, Navratilova M, Foretova L, Gerdes AM, Roos-Blom MJ, Van Leeuwen FE, Arver B, Olsson H, Schmutzler RK, Engel C, Kast K, Phillips KA, Terry MB, Milne RL, Goldgar DE, Rookus MA, Andrieu N, Easton DF, Ibccs, kConFab, and Bcfr (2020). Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers. Breast Cancer Res22, 8. doi:10.1186/s13058-020-1247-4.
  • Mayr SJ, Roper J, and Schwarz G (2020). Alternative splicing of the bicistronic gene molybdenum cofactor synthesis 1 (MOCS1) uncovers a novel mitochondrial protein maturation mechanism. J Biol Chem295, 3029-3039. doi:10.1074/jbc.RA119.010720.
  • Mehrjardi NZ, Molcanyi M, Hatay FF, Timmer M, Shahbazi E, Ackermann JP, Herms S, Heilmann-Heimbach S, Wunderlich TF, Prochnow N, Haghikia A, Lampert A, Hescheler J, Neugebauer EAM, Baharvand H, and Saric T (2020). Acquisition of chromosome 1q duplication in parental and genome-edited human-induced pluripotent stem cell-derived neural stem cells results in their higher proliferation rate in vitro and in vivo. Cell Prolif53, e12892. doi:10.1111/cpr.12892.
  • Meinrath J, Haak A, Igci N, Dalvi P, Arolt C, Meemboor S, Siebolts U, Eischeidt-Scholz H, Wickenhauser C, Grunewald I, Drebber U, Buttner R, Quaas A, Klussmann JP, Odenthal M, Beutner D, and Meyer M (2020). Expression profiling on subclasses of primary parotid gland carcinomas. Oncotarget 11, 4123-4137. doi:10.18632/oncotarget.27797.
  • Meisig J , Dreser  N, Kapitza M,  Henry M,  Rotshteyn T, Rahnenführer J, Hengstler, JG, Sachinidis A, Waldmann T, Leist M, Blüthgen N. (2020) Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation. Nucleic Acids Res48, 12577-12592. doi: 10.1093/nar/gkaa1089.
  • Mendoza-Ferreira N, Karakaya M, Cengiz N, Beijer D, Brigatti KW, Gonzaga-Jauregui C, Fuhrmann N, Holker I, Thelen MP, Zetzsche S, Rombo R, Puffenberger EG, De Jonghe P, Deconinck T, Zuchner S, Strauss KA, Carson V, Schrank B, Wunderlich G, Baets J, and Wirth B (2020). De Novo and Inherited Variants in GBF1 are Associated with Axonal Neuropathy Caused by Golgi Fragmentation. Am J Hum Genet107, 763-777. doi:10.1016/j.ajhg.2020.08.018.
  • Meyer AM, Becker I, Siri G, Brinkkotter PT, Benzing T, Pilotto A, and Polidori MC (2020). The prognostic significance of geriatric syndromes and resources. Aging Clin Exp Res32, 115-124. doi:10.1007/s40520-019-01168-9.
  • Mizi A, Gade Gusmao E, and Papantonis A (2020). iHi-C 2.0: A simple approach for mapping native spatial chromatin organisation from low cell numbers. Methods170, 33-37. doi:10.1016/j.ymeth.2019.07.003.
  • Mollenhauer M, Mehrkens D, Klinke A, Lange M, Remane L, Friedrichs K, Braumann S, Geissen S, Simsekyilmaz S, Nettersheim FS, Lee S, Peinkofer G, Geisler AC, Geis B, Schwoerer AP, Carrier L, Freeman BA, Dewenter M, Luo X, El-Armouche A, Wagner M, Adam M, Baldus S, and Rudolph V (2020). Nitro-fatty acids suppress ischemic ventricular arrhythmias by preserving calcium homeostasis. Sci Rep10, 15319. doi:10.1038/s41598-020-71870-6.
  • Mufazalov IA, Andruszewski D, Schelmbauer C, Heink S, Blanfeld M, Masri J, Tang Y, Schuler R, Eich C, Wunderlich FT, Karbach SH, Bluestone JA, Korn T, and Waisman A (2020). Cutting Edge: IL-6-Driven Immune Dysregulation Is Strictly Dependent on IL-6R alpha-Chain Expression. J Immunol204, 747-751. doi:10.4049/jimmunol.1900876.
  • Muke I, Sprenger A, Bobylev I, Wiemer V, Barham M, Neiss WF, and Lehmann HC (2020). Ultrastructural characterization of mitochondrial damage in experimental autoimmune neuritis. Journal of Neuroimmunology343. doi:ARTN 577218 10.1016/j.jneuroim.2020.577218.
  • Muranen TA, Khan S, Fagerholm R, Aittomaki K, Cunningham JM, Dennis J, Leslie G, McGuffog L, Parsons MT, Simard J, Slager S, Soucy P, Easton DF, Tischkowitz M, Spurdle AB, kConFab I, Schmutzler RK, Wappenschmidt B, Hahnen E, Hooning MJ, Investigators H, Singer CF, Wagner G, Thomassen M, Pedersen IS, Domchek SM, Nathanson KL, Lazaro C, Rossing CM, Andrulis IL, Teixeira MR, James P, Garber J, Weitzel JN, Investigators S-B, Jakubowska A, Yannoukakos D, John EM, Southey MC, Schmidt MK, Antoniou AC, Chenevix-Trench G, Blomqvist C, and Nevanlinna H (2020). Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer. NPJ Breast Cancer6, 44. doi:10.1038/s41523-020-00185-6.
  • Mus LM, Lambertz I, Claeys S, Kumps C, Van Loocke W, Van Neste C, Umapathy G, Vaapil M, Bartenhagen C, Laureys G, De Wever O, Bexell D, Fischer M, Hallberg B, Schulte J, De Wilde B, Durinck K, Denecker G, De Preter K, and Speleman F (2020). The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness. Sci Rep10, 218. doi:10.1038/s41598-019-57076-5.
  • Nattramilarasu PK, Bucker R, Lobo de Sa FD, Fromm A, Nagel O, Lee IM, Butkevych E, Mousavi S, Genger C, Klove S, Heimesaat MM, Bereswill S, Schweiger MR, Nielsen HL, Troeger H, and Schulzke JD (2020). Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption. Int J Mol Sci21. doi:10.3390/ijms21020373.
  • Nava MM, Miroshnikova YA, Biggs LC, Whitefield DB, Metge F, Boucas J, Vihinen H, Jokitalo E, Li X, Garcia Arcos JM, Hoffmann B, Merkel R, Niessen CM, Dahl KN, and Wickstrom SA (2020). Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage. Cell181, 800-817 e822. doi:10.1016/j.cell.2020.03.052.
  • Nemade H, Acharya A, Chaudhari U, Nembo E, Nguemo F, Riet N, Abken H, Hescheler J, Papadopoulos S, and Sachinidis A (2020). Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells. Cells9. doi:10.3390/cells9030554.
  • Nemeth CL, Tomlinson SN, Rosen M, O'Brien BM, Larraza O, Jain M, Murray CF, Marx JS, Delannoy M, Fine AS, Wu D, Trifunovic A, and Fatemi A (2020). Neuronal ablation of mt-AspRS in mice induces immune pathway activation prior to severe and progressive cortical and behavioral disruption. Exp Neurol326, 113164. doi:10.1016/j.expneurol.2019.113164.
  • Niessen CM, and Plachta N (2020). Emerging mechanisms driving cell differentiation in vivo. Curr Opin Cell Biol. doi:10.1016/j.ceb.2020.10.003.
  • Niessl J, Baxter AE, Mendoza P, Jankovic M, Cohen YZ, Butler AL, Lu CL, Dube M, Shimeliovich I, Gruell H, Klein F, Caskey M, Nussenzweig MC, and Kaufmann DE (2020). Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity. Nat Med26, 222-227. doi:10.1038/s41591-019-0747-1.
  • Niestroj LM, Perez-Palma E, Howrigan DP, Zhou Y, Cheng F, Saarentaus E, Nurnberg P, Stevelink R, Daly MJ, Palotie A, Lal D, and Epi C (2020). Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects. Brain143, 2106-2118. doi:10.1093/brain/awaa171.
  • Nusken E, Fink G, Lechner F, Voggel J, Wohlfarth M, Sprenger L, Mehdiani N, Weber LT, Liebau MC, Brachvogel B, Dotsch J, and Nusken KD (2020). Altered molecular signatures during kidney development after intrauterine growth restriction of different origins. J Mol Med (Berl)98, 395-407. doi:10.1007/s00109-020-01875-1.
  • Oberbeck S, Schrader A, Warner K, Jungherz D, Crispatzu G, von Jan J, Chmielewski M, Ianevski A, Diebner HH, Mayer P, Kondo Ados A, Wahnschaffe L, Braun T, Muller TA, Wagle P, Bouska A, Neumann T, Putzer S, Varghese L, Pflug N, Thelen M, Makalowski J, Riet N, Gox HJM, Rappl G, Altmuller J, Kotrova M, Persigehl T, Hopfinger G, Hansmann ML, Schlosser H, Stilgenbauer S, Durig J, Mougiakakos D, von Bergwelt-Baildon M, Roeder I, Hartmann S, Hallek M, Moriggl RH, Bruggemann M, Aittokallio T, Iqbal J, Newrzela S, Abken H, and Herling M (2020). Non-canonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling. Blood. doi:10.1182/blood.2019003348.
  • Oexner RR, Pla-Martin D, Pass T, Wiesen MHJ, Zentis P, Schauss A, Baris OR, Kimoloi S, and Wiesner RJ (2020). Extraocular Muscle Reveals Selective Vulnerability of Type IIB Fibers to Respiratory Chain Defects Induced by Mitochondrial DNA Alterations. Invest Ophthalmol Vis Sci61, 14. doi:10.1167/iovs.61.12.14.
  • Ornek Erguzeloglu C, Kara B, Karacan I, Ozdemir O, Kesim Y, Bebek N, Ozbek U, and Ugur Iseri SA (2020). Screening Slc2a1 Gene for Sequence and Copy Number Variations Associated with Glut-1 Deficiency Syndrome. Journal of Istanbul Faculty of Medicine-Istanbul Tip Fakultesi Dergisi83, 177-183. doi:10.26650/Iuitfd.2019.0064.
  • Otte MS, Eckel HNC, Poluschkin L, Klussmann JP, and Luers JC (2020). Olfactory dysfunction in patients after recovering from COVID-19. Acta Otolaryngol, 1-4. doi:10.1080/00016489.2020.1811999.
  • Paketci C, Karakaya M, Edem P, Bayram E, Keller N, Daimaguler HS, Cirak S, Jordanova A, Hiz S, Wirth B, and Yis U (2020). Clinical, electrophysiological and genetic characteristics of childhood hereditary polyneuropathies. Rev Neurol (Paris). doi:10.1016/j.neurol.2020.04.016.
  • Patasic L, Seifried J, Bezler V, Kaljanac M, Schneider IC, Schmitz H, Tondera C, Hartmann J, Hombach A, Buchholz CJ, Abken H, Konig R, and Cichutek K (2020). Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4(+) T cells to reduce the latent HIV(+) cell reservoir. Med Microbiol Immunol209, 681-691. doi:10.1007/s00430-020-00692-0.
  • Patel VL, Busch EL, Friebel TM, Cronin A, Leslie G, McGuffog L, Adlard J, Agata S, Agnarsson BA, Ahmed M, Aittomaki K, Alducci E, Andrulis IL, Arason A, Arnold N, Artioli G, Arver B, Auber B, Azzollini J, Balmana J, Barkardottir RB, Barnes DR, Barroso A, Barrowdale D, Belotti M, Benitez J, Bertelsen B, Blok MJ, Bodrogi I, Bonadona V, Bonanni B, Bondavalli D, Boonen SE, Borde J, Borg A, Bradbury AR, Brady A, Brewer C, Brunet J, Buecher B, Buys SS, Cabezas-Camarero S, Caldes T, Caliebe A, Caligo MA, Calvello M, Campbell IG, Carnevali I, Carrasco E, Chan TL, Chu ATW, Chung WK, Claes KBM, Collaborators GS, Collaborators E, Cook J, Cortesi L, Couch FJ, Daly MB, Damante G, Darder E, Davidson R, de la Hoya M, Puppa LD, Dennis J, Diez O, Ding YC, Ditsch N, Domchek SM, Donaldson A, Dworniczak B, Easton DF, Eccles DM, Eeles RA, Ehrencrona H, Ejlertsen B, Engel C, Evans DG, Faivre L, Faust U, Feliubadalo L, Foretova L, Fostira F, Fountzilas G, Frost D, Garcia-Barberan V, Garre P, Gauthier-Villars M, Geczi L, Gehrig A, Gerdes AM, Gesta P, Giannini G, Glendon G, Godwin AK, Goldgar DE, Greene MH, Gutierrez-Barrera AM, Hahnen E, Hamann U, Hauke J, Herold N, Hogervorst FBL, Honisch E, Hopper JL, Hulick PJ, Investigators K, Investigators H, Izatt L, Jager A, James P, Janavicius R, Jensen UB, Jensen TD, Johannsson OT, John EM, Joseph V, Kang E, Kast K, Kiiski JI, Kim SW, Kim Z, Ko KP, Konstantopoulou I, Kramer G, Krogh L, Kruse TA, Kwong A, Larsen M, Lasset C, Lautrup C, Lazaro C, Lee J, Lee JW, Lee MH, Lemke J, Lesueur F, Liljegren A, Lindblom A, Llovet P, Lopez-Fernandez A, Lopez-Perolio I, Lorca V, Loud JT, Ma ESK, Mai PL, Manoukian S, Mari V, Martin L, Matricardi L, Mebirouk N, Medici V, Meijers-Heijboer HEJ, Meindl A, Mensenkamp AR, Miller C, Gomes DM, Montagna M, Mooij TM, Moserle L, Mouret-Fourme E, Mulligan AM, Nathanson KL, Navratilova M, Nevanlinna H, Niederacher D, Nielsen FCC, Nikitina-Zake L, Offit K, Olah E, Olopade OI, Ong KR, Osorio A, Ott CE, Palli D, Park SK, Parsons MT, Pedersen IS, Peissel B, Peixoto A, Perez-Segura P, Peterlongo P, Petersen AH, Porteous ME, Pujana MA, Radice P, Ramser J, Rantala J, Rashid MU, Rhiem K, Rizzolo P, Robson ME, Rookus MA, Rossing CM, Ruddy KJ, Santos C, Saule C, Scarpitta R, Schmutzler RK, Schuster H, Senter L, Seynaeve CM, Shah PD, Sharma P, Shin VY, Silvestri V, Simard J, Singer CF, Skytte AB, Snape K, Solano AR, Soucy P, Southey MC, Spurdle AB, Steele L, Steinemann D, Stoppa-Lyonnet D, Stradella A, Sunde L, Sutter C, Tan YY, Teixeira MR, Teo SH, Thomassen M, Tibiletti MG, Tischkowitz M, Tognazzo S, Toland AE, Tommasi S, Torres D, Toss A, Trainer AH, Tung N, van Asperen CJ, van der Baan FH, van der Kolk LE, van der Luijt RB, van Hest LP, Varesco L, Varon-Mateeva R, Viel A, Vierstraete J, Villa R, von Wachenfeldt A, Wagner P, Wang-Gohrke S, Wappenschmidt B, Weitzel JN, Wieme G, Yadav S, Yannoukakos D, Yoon SY, Zanzottera C, Zorn KK, D'Amico AV, Freedman ML, Pomerantz MM, Chenevix-Trench G, Antoniou AC, Neuhausen SL, Ottini L, Nielsen HR, and Rebbeck TR (2020). Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness. Cancer Res80, 624-638. doi:10.1158/0008-5472.CAN-19-1840.
  • Patil P, Cieslak A, Bernhart SH, Toprak UH, Wagener R, Lopez C, Wiehle L, Bens S, Altmuller J, Franitza M, Scholz I, Jayne S, Ahearne MJ, Scheffold A, Jebaraj BMC, Schneider C, Costa D, Braun T, Schrader A, Campo E, Dyer MJS, Nurnberg P, Durig J, Johansson P, Bottcher S, Schlesner M, Herling M, Stilgenbauer S, Macintyre E, and Siebert R (2020). Reconstruction of rearranged T-cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T-cell prolymphocytic leukemia. Genes Chromosomes Cancer59, 261-267. doi:10.1002/gcc.22821.
  • Pavinato L, Villamor-Paya M, Sanchiz-Calvo M, Andreoli C, Gay M, Vilaseca M, Arauz-Garofalo G, Ciolfi A, Bruselles A, Pippucci T, Prota V, Carli D, Giorgio E, Radio FC, Antona V, Giuffre M, Ranguin K, Colson C, De Rubeis S, Dimartino P, Buxbaum JD, Ferrero GB, Tartaglia M, Martinelli S, Stracker TH, and Brusco A (2020). Functional analysis of TLK2 variants and their proximal interactomes implicates impaired kinase activity and chromatin maintenance defects in their pathogenesis. J Med Genet. doi:10.1136/jmedgenet-2020-107281.
  • Peitz C, Sprüssel A, Linke RB, Astrahanseff K, Grimaldi M, Schmelz K, Toedling J, Schulte JH, Fischer M, Messerschmidt C, Beule D, Keilholz U, Eggert A, Deubzer HE, Lodrini M (2020). Multiplexed quantification of four neuroblastoma DNA targets in a single droplet digital PCR reaction. J Mol Diagn 22(11): 1309-1323. doi: 10.1016/j.jmoldx.2020.07.006.
  • Pergande M, Motameny S, Ozdemir O, Kreutzer M, Wang H, Daimaguler HS, Becker K, Karakaya M, Ehrhardt H, Elcioglu N, Ostojic S, Chao CM, Kawalia A, Duman O, Koy A, Hahn A, Reimann J, Schoner K, Schanzer A, Westhoff JH, Schwaibold EMC, Cossee M, Imbert-Bouteille M, von Pein H, Haliloglu G, Topaloglu H, Altmuller J, Nurnberg P, Thiele H, Heller R, and Cirak S (2020). The genomic and clinical landscape of fetal akinesia. Genet Med22, 511-523. doi:10.1038/s41436-019-0680-1.
  • Peters F, Tellkamp F, Brodesser S, Wachsmuth E, Tosetti B, Karow U, Bloch W, Utermohlen O, Kronke M, and Niessen CM (2020). Murine Epidermal Ceramide Synthase 4 Is a Key Regulator of Skin Barrier Homeostasis. J Invest Dermatol. doi:10.1016/j.jid.2020.02.006.
  • Pinatti LM, Walline HM, Carey TE, Klussmann JP, and Huebbers CU (2020). Viral Integration Analysis Reveals Likely Common Clonal Origin of Bilateral HPV16-Positive, p16-Positive Tonsil Tumors. Arch Clin Med Case Rep4, 680-696. doi:10.26502/acmcr.96550248.
  • Pla-Martin D, Schatton D, Wiederstein JL, Marx MC, Khiati S, Kruger M, and Rugarli EI (2020). CLUH granules coordinate translation of mitochondrial proteins with mTORC1 signaling and mitophagy. EMBO J39, e102731. doi:10.15252/embj.2019102731.
  • Pohl-Rescigno E, Hauke J, Loibl S, Mobus V, Denkert C, Fasching PA, Kayali M, Ernst C, Weber-Lassalle N, Hanusch C, Tesch H, Muller V, Altmuller J, Thiele H, Untch M, Lubbe K, Nurnberg P, Rhiem K, Furlanetto J, Lederer B, Jackisch C, Nekljudova V, Schmutzler RK, Schneeweiss A, and Hahnen E (2020). Association of Germline Variant Status With Therapy Response in High-risk Early-Stage Breast Cancer: A Secondary Analysis of the GeparOcto Randomized Clinical Trial. JAMA Oncol. doi:10.1001/jamaoncol.2020.0007.
  • Polanyi L, Niessen CM, Vohlen C, Stinn J, Kretschmer T, Jentgen V, Hirani D, Koningsbruggen-Rietschel SV, Dotsch J, and Alejandre Alcazar MA (2020). Intrauterine growth restriction induces skin inflammation, increases TSLP and impairs epidermal barrier function. J Mol Med (Berl)98, 279-289. doi:10.1007/s00109-019-01867-w.
  • Ramani A, Muller L, Ostermann PN, Gabriel E, Abida-Islam P, Muller-Schiffmann A, Mariappan A, Goureau O, Gruell H, Walker A, Andree M, Hauka S, Houwaart T, Dilthey A, Wohlgemuth K, Omran H, Klein F, Wieczorek D, Adams O, Timm J, Korth C, Schaal H, and Gopalakrishnan J (2020). SARS-CoV-2 targets neurons of 3D human brain organoids. EMBO J39, e106230. doi:10.15252/embj.2020106230.
  • Rashid K, Verhoyen M, Taiwo M, and Langmann T (2020). Translocator protein (18 kDa) (TSPO) ligands activate Nrf2 signaling and attenuate inflammatory responses and oxidative stress in human retinal pigment epithelial cells. Biochem Biophys Res Commun. doi:10.1016/j.bbrc.2020.05.114.
  • Rasool S, Baig JM, Moawia A, Ahmad I, Iqbal M, Waseem SS, Asif M, Abdullah U, Makhdoom EUH, Kaygusuz E, Zakaria M, Ramzan S, Haque SU, Mir A, Anjum I, Fiaz M, Ali Z, Tariq M, Saba N, Hussain W, Budde B, Irshad S, Noegel AA, Honing S, Baig SM, Nurnberg P, and Hussain MS (2020). An update of pathogenic variants in ASPM, WDR62, CDK5RAP2, STIL, CENPJ, and CEP135 underlying autosomal recessive primary microcephaly in 32 consanguineous families from Pakistan. Mol Genet Genomic Med8, e1408. doi:10.1002/mgg3.1408.
  • Raspa M, Paoletti R, Mahabir E, and Scavizzi F (2020). d-aspartate treatment in vitro improves mouse sperm fertility in young B6N mice. Theriogenology148, 60-67. doi:10.1016/j.theriogenology.2020.02.031.
  • Reder H, Taferner VF, Wittekindt C, Brauninger A, Speel EM, Gattenlohner S, Wolf G, Klussmann JP, Wuerdemann N, and Wagner S (2020). Plasma Cell-Free Human Papillomavirus Oncogene E6 and E7 DNA Predicts Outcome in Oropharyngeal Squamous Cell Carcinoma. J Mol Diagn. doi:10.1016/j.jmoldx.2020.08.002.
  • Reinke S, Bröckelmann PJ, Iaccarino I, Garcia-Marquez M, Borchmann S, Jochims F, Kotrova M, Pal K, Brüggemann M, Hartmann E, Sasse S, Kobe C, Mathas S, Soekler M, Keller U, Bormann M, Zimmermann A, Richter J, Fuchs M, von Tresckow B, Borchmann P, Schlößer HA, von Bergwelt-Baildon M, Rosenwald A, Engert A, Klapper W. Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1. Blood. 2020 Dec 17;136(25):2851-2863. doi: 10.1182/blood.2020008553.
  • Renner AM, Ilyas S, Schlosser HA, Szymura A, Roitsch S, Wennhold K, and Mathur S (2020). Receptor-Mediated In Vivo Targeting of Breast Cancer Cells with 17alpha-Ethynylestradiol-Conjugated Silica-Coated Gold Nanoparticles. Langmuir. doi:10.1021/acs.langmuir.0c02820.
  • Riabinska A, Lehrmann D, Jachimowicz RD, Knittel G, Fritz C, Schmitt A, Geyer A, Heneweer C, Wittersheim M, Frenzel LP, Torgovnick A, Wiederstein JL, Wunderlich CM, Ortmann M, Paillard A, Wossmann W, Borkhardt A, Burdach S, Hansmann ML, Rosenwald A, Perner S, Mall G, Klapper W, Merseburg A, Kruger M, Grull H, Persigehl T, Wunderlich FT, Peifer M, Utermohlen O, Buttner R, Beleggia F, and Reinhardt HC (2020). ATM activity in T cells is critical for immune surveillance of lymphoma in vivo. Leukemia34, 771-786. doi:10.1038/s41375-019-0618-2.
  • Ricke KM, Pass T, Kimoloi S, Fahrmann K, Jungst C, Schauss A, Baris OR, Aradjanski M, Trifunovic A, Eriksson Faelker TM, Bergami M, and Wiesner RJ (2020). Mitochondrial Dysfunction Combined with High Calcium Load Leads to Impaired Antioxidant Defense Underlying the Selective Loss of Nigral Dopaminergic Neurons. J Neurosci40, 1975-1986. doi:10.1523/JNEUROSCI.1345-19.2019.
  • Rosenkranz S, Howard LS, Gomberg-Maitland M, and Hoeper MM (2020). Systemic Consequences of Pulmonary Hypertension and Right-Sided Heart Failure. Circulation141, 678-693. doi:10.1161/CIRCULATIONAHA.116.022362.
  • Ruegenberg S, Horn M, Pichlo C, Allmeroth K, Baumann U, and Denzel MS (2020). Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun11, 687. doi:10.1038/s41467-020-14524-5.
  • Rumyantseva A, Motori E, and Trifunovic A (2020). DARS2 is indispensable for Purkinje cell survival and protects against cerebellar ataxia. Hum Mol Genet 29, 2845-2854. doi:10.1093/hmg/ddaa176.
  • Ruud LE, Pereira MMA, de Solis AJ, Fenselau H, and Bruning JC (2020). NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons. Nature Communications11. doi:ARTN 442 10.1038/s41467-020-14291-3.
  • Rybniker J, and Fatkenheuer G (2020). Importance of precise data on SARS-CoV-2 transmission dynamics control. Lancet Infect Dis. doi:10.1016/S1473-3099(20)30359-5.
  • Sahu P, Sussman DM, Rubsam M, Mertz AF, Horsley V, Dufresne ER, Niessen CM, Marchetti MC, Manning ML, and Schwarz JM (2020). Small-scale demixing in confluent biological tissues. Soft Matter16, 3325-3337. doi:10.1039/c9sm01084j.
  • Salabarria AC, Koch M, Schonberg A, Zinser E, Hos D, Hamdorf M, Imhof T, Braun G, Cursiefen C, and Bock F (2020). Topical VEGF-C/D Inhibition Prevents Lymphatic Vessel Ingrowth into Cornea but Does Not Improve Corneal Graft Survival. J Clin Med9. doi:10.3390/jcm9051270.
  • Salmanton-Garcia J, Koehler P, Kindo A, Falces-Romero I, Garcia-Rodriguez J, Racil Z, Chen SC, Klimko N, Desoubeaux G, Thompson Gr, III, Benitez-Penuela MA, Rodriguez JY, Sheppard DC, Hoenigl M, Le Govic Y, Badali H, Baddley JW, Chander J, Ingram PR, Pakstis DL, Mellinghoff SC, Atici S, Cesaro S, Chakrabarti A, Dupont D, Gonzalez GM, Hatvani L, Herbrecht R, Klyasova G, Lass-Florl C, Mares M, Mullane K, Vinh DC, Wisplinghoff H, Lackner M, Cornely OA, Seidel D, and group EIw (2020). Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope()-Global Registry for Emerging Fungal Infections. J Infect81, 802-815. doi:10.1016/j.jinf.2020.08.015.
  • Sauvigny T, Alawi M, Krause L, Renner S, Spohn M, Busch A, Kolbe V, Altmuller J, Loscher BS, Franke A, Brockmann C, Lieb W, Westphal M, Schmidt NO, Regelsberger J, and Rosenberger G (2020). Exome sequencing in 38 patients with intracranial aneurysms and subarachnoid hemorrhage. J Neurol. doi:10.1007/s00415-020-09865-6.
  • Schaub F, Collmer M, Schrittenlocher S, Bachmann BO, Cursiefen C, and Hos D (2020). Outcome of Descemet Membrane Endothelial Keratoplasty Using Corneas from Donors >/=80 Years of Age. Am J Ophthalmol211, 200-206. doi:10.1016/j.ajo.2019.12.001.
  • Schermer B, Fabretti F, Damagnez M, Di Cristanziano V, Heger E, Arjune S, Tanner NA, Imhof T, Koch M, Ladha A, Joung J, Gootenberg JS, Abudayyeh OO, Burst V, Zhang F, Klein F, Benzing T, and Muller RU (2020). Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay. PLoS One15, e0238612. doi:10.1371/journal.pone.0238612.
  • Schiffmann LM, Werthenbach JP, Heintges-Kleinhofer F, Seeger JM, Fritsch M, Gunther SD, Willenborg S, Brodesser S, Lucas C, Jungst C, Albert MC, Schorn F, Witt A, Moraes CT, Bruns CJ, Pasparakis M, Kronke M, Eming SA, Coutelle O, and Kashkar H (2020). Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth. Nature Communications11. doi:Artn 3653 10.1038/S41467-020-17472-2.
  • Schommers P, Gruell H, Abernathy ME, Tran MK, Dingens AS, Gristick HB, Barnes CO, Schoofs T, Schlotz M, Vanshylla K, Kreer C, Weiland D, Holtick U, Scheid C, Valter MM, van Gils MJ, Sanders RW, Vehreschild JJ, Cornely OA, Lehmann C, Fatkenheuer G, Seaman MS, Bloom JD, Bjorkman PJ, and Klein F (2020). Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell180, 471-489 e422. doi:10.1016/j.cell.2020.01.010.
  • Schonermarck U, Ries W, Schroppel B, Pape L, Dunaj-Kazmierowska M, Burst V, Mitzner S, Basara N, Starck M, Schmidbauer D, Mellmann A, Dittmer R, Jeglitsch M, and Haas CS (2020). Relative incidence of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome in clinically suspected cases of thrombotic microangiopathy. Clin Kidney J13, 208-216. doi:10.1093/ckj/sfz066.
  • Schönborn K, Willenborg S,  Schulz J N, Imhof T, Eming S A, Quondamatteo F, Brinckmann J,  Niehoff A, Paulsson M, Koch M, Eckes B, Krieg T. Role of collagen XII in skin homeostasis and repair. Matrix Biol 2020 Vol. 94 Pages 57-76, Accession Number: 32890632 DOI: 10.1016/j.matbio.2020.08.002.
  • Schrittenlocher S, Schlereth SL, Siebelmann S, Hayashi T, Matthaei M, Bachmann B, and Cursiefen C (2020). Long-term outcome of descemet membrane endothelial keratoplasty (DMEK) following failed penetrating keratoplasty (PK). Acta Ophthalmol. doi:10.1111/aos.14417.
  • Schuster R, Anton V, Simoes T, Altin S, den Brave F, Hermanns T, Hospenthal M, Komander D, Dittmar G, Dohmen RJ, and Escobar-Henriques M (2020). Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation. Life Sci Alliance3. doi:10.26508/lsa.201900476.
  • Schwarzer, R., Jiao, H., Wachsmuth, L., Tresch, A. & Pasparakis, M. FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells. Immunity 52, 978-993.e6 (2020).
  • Scicluna BP, Uhel F, van Vught LA, Wiewel MA, Hoogendijk AJ, Baessman I, Franitza M, Nurnberg P, Horn J, Cremer OL, Bonten MJ, Schultz MJ, van der Poll T, Molecular D, and Risk Stratification in Sepsis c (2020). The leukocyte non-coding RNA landscape in critically ill patients with sepsis. Elife9. doi:10.7554/eLife.58597.
  • Sikora P, Zaniew M, Grenda R, Jobs K, Rubik J, Zawadzki J, Myślak M, Durlik M, Erger F, Bieniaś B, Hoppe B, Beck BB. Still diagnosed too late and under-recognized? The first comprehensive report on primary hyperoxaluria in Poland. Pol Arch Intern Med. 2020 Dec 22;130(12):1053-1063. doi: 10.20452/pamw.15698.
  • Siedek F, Grundmann F, Weiss K, Pinto Dos Santos D, Arjune S, Haneder S, Persigehl T, Muller RU, and Baessler B (2020). Magnetic Resonance Kidney Parenchyma-T2 as a Novel Imaging Biomarker for Autosomal Dominant Polycystic Kidney Disease. Invest Radiol55, 217-225. doi:10.1097/RLI.0000000000000633.
  • Siggel R, Schroedl F, Dietlein T, Koch KR, Platzl C, Kaser-Eichberger A, Cursiefen C, and Heindl LM (2020). Absence of lymphatic vessels in non-functioning bleb capsules of glaucoma drainage devices. Histol Histopathol, 18300. doi:10.14670/HH-18-300.
  • Silvestri V, Leslie G, Barnes DR, Group C, Agnarsson BA, Aittomaki K, Alducci E, Andrulis IL, Barkardottir RB, Barroso A, Barrowdale D, Benitez J, Bonanni B, Borg A, Buys SS, Caldes T, Caligo MA, Capalbo C, Campbell I, Chung WK, Claes KBM, Colonna SV, Cortesi L, Couch FJ, de la Hoya M, Diez O, Ding YC, Domchek S, Easton DF, Ejlertsen B, Engel C, Evans DG, Feliubadalo L, Foretova L, Fostira F, Geczi L, Gerdes AM, Glendon G, Godwin AK, Goldgar DE, Hahnen E, Hogervorst FBL, Hopper JL, Hulick PJ, Isaacs C, Izquierdo A, James PA, Janavicius R, Jensen UB, John EM, Joseph V, Konstantopoulou I, Kurian AW, Kwong A, Landucci E, Lesueur F, Loud JT, Machackova E, Mai PL, Majidzadeh AK, Manoukian S, Montagna M, Moserle L, Mulligan AM, Nathanson KL, Nevanlinna H, Ngeow J, Nikitina-Zake L, Offit K, Olah E, Olopade OI, Osorio A, Papi L, Park SK, Pedersen IS, Perez-Segura P, Petersen AH, Pinto P, Porfirio B, Pujana MA, Radice P, Rantala J, Rashid MU, Rosenzweig B, Rossing M, Santamarina M, Schmutzler RK, Senter L, Simard J, Singer CF, Solano AR, Southey MC, Steele L, Steinsnyder Z, Stoppa-Lyonnet D, Tan YY, Teixeira MR, Teo SH, Terry MB, Thomassen M, Toland AE, Torres-Esquius S, Tung N, van Asperen CJ, Vega A, Viel A, Vierstraete J, Wappenschmidt B, Weitzel JN, Wieme G, Yoon SY, Zorn KK, McGuffog L, Parsons MT, Hamann U, Greene MH, Kirk JA, Neuhausen SL, Rebbeck TR, Tischkowitz M, Chenevix-Trench G, Antoniou AC, Friedman E, and Ottini L (2020). Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). JAMA Oncol6, 1218-1230. doi:10.1001/jamaoncol.2020.2134.
  • Solomon-Degefa H, Gebauer JM, Jeffries CM, Freiburg CD, Meckelburg P, Bird LE, Baumann U, Svergun DI, Owens RJ, Werner JM, Behrmann E, Paulsson M, and Wagener R (2020). Structure of a collagen VI alpha 3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations. Journal of Biological Chemistry295, 12755-12771. doi:10.1074/jbc.RA120.014865.
  • Spiro JE, Rinneburger M, Hedderich DM, Jokic M, Reinhardt HC, Maintz D, Palmowski M, and Persigehl T (2020). Monitoring treatment effects in lung cancer-bearing mice: clinical CT and clinical MRI compared to micro-CT. Eur Radiol Exp4, 31. doi:10.1186/s41747-020-00160-7.
  • Spitali P, Zaharieva I, Bohringer S, Hiller M, Chaouch A, Roos A, Scotton C, Claustres M, Bello L, McDonald CM, Hoffman EP, Investigators C, Koeks Z, Eka Suchiman H, Cirak S, Scoto M, Reza M, t Hoen PAC, Niks EH, Tuffery-Giraud S, Lochmuller H, Ferlini A, Muntoni F, and Aartsma-Rus A (2020). TCTEX1D1 is a genetic modifier of disease progression in Duchenne muscular dystrophy. Eur J Hum Genet28, 815-825. doi:10.1038/s41431-019-0563-6.
  • Sprute R, Salmanton-Garcia J, Sal E, Malaj X, Falces-Romero I, Hatvani L, Heinemann M, Klimko N, Lopez-Soria L, Meletiadis J, Shruti M, Steinmann J, Seidel D, Cornely OA, and Stemler J (2020). Characterization and outcome of invasive infections due to Paecilomyces variotii: analysis of patients from the FungiScope(R) registry and literature reports. J Antimicrob Chemother. doi:10.1093/jac/dkaa481.
  • Stanicek L, Lozano-Vidal N, Bink DI, Hooglugt A, Yao W, Wittig I, van Rijssel J, van Buul JD, van Bergen A, Klems A, Ramms AS, Le Noble F, Hofmann P, Szulcek R, Wang S, Offermanns S, Ercanoglu MS, Kwon HB, Stainier D, Huveneers S, Kurian L, Dimmeler S, and Boon RA (2020). Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function. Commun Biol3, 265. doi:10.1038/s42003-020-0987-0.
  • Stankovic D, Claudius AK, Schertel T, Bresser T, and Uhlirova M (2020). Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8. Dis Model Mech. doi:10.1242/dmm.043174.
  • Stoffel W, Schmidt-Soltau I, Binczek E, Thomas A, Thevis M, and Wegner I (2020). Dietary omega3-and omega6-Polyunsaturated fatty acids reconstitute fertility of Juvenile and adult Fads2-Deficient mice. Mol Metab36, 100974. doi:10.1016/j.molmet.2020.100974.
  • Sur-Erdem I, Hussain MS, Asif M, Pinarbasi N, Aksu AC, and Noegel AA (2020). Nesprin-1 impact on tumorigenic cell phenotypes. Mol Biol Rep47, 921-934. doi:10.1007/s11033-019-05184-w.
  • Szczepanowska K, Senft K, Heidler J, Herholz M, Kukat A, Hohne MN, Hofsetz E, Becker C, Kaspar S, Giese H, Zwicker K, Guerrero-Castillo S, Baumann L, Kauppila J, Rumyantseva A, Muller S, Frese CK, Brandt U, Riemer J, Wittig I, and Trifunovic A (2020). A salvage pathway maintains highly functional respiratory complex I. Nat Commun11, 1643. doi:10.1038/s41467-020-15467-7.
  • Tellkamp F, Lang F, Ibanez A, Abraham L, Quezada G, Gunther S, Looso M, Tann FJ, Muller D, Cemic F, Hemberger J, Steinfartz S, and Kruger M (2020). Proteomics of Galapagos Marine Iguanas Links Function of Femoral Gland Proteins to the Immune System. Mol Cell Proteomics19, 1523-1532. doi:10.1074/mcp.RA120.001947.
  • Thalheim T, Hopp L, Herberg M, Siebert S, Kerner C, Quaas M, Schweiger MR, Aust G, and Galle J (2020). Fighting Against Promoter DNA Hyper-Methylation: Protective Histone Modification Profiles of Stress-Resistant Intestinal Stem Cells. Int J Mol Sci21. doi:10.3390/ijms21061941.
  • Thelen MP, Wirth B, and Kye MJ (2020). Mitochondrial defects in the respiratory complex I contribute to impaired translational initiation via ROS and energy homeostasis in SMA motor neurons. Acta Neuropathol Commun8, 223. doi:10.1186/s40478-020-01101-6.
  • Theobald SJ, Kreer C, Khailaie S, Bonifacius A, Eiz-Vesper B, Figueiredo C, Mach M, Backovic M, Ballmaier M, Koenig J, Olbrich H, Schneider A, Volk V, Danisch S, Gieselmann L, Ercanoglu MS, Messerle M, Kaisenberg CV, Witte T, Klawonn F, Meyer-Hermann M, Klein F, and Stripecke R (2020). Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV. PLoS Pathog16, e1008560. doi:10.1371/journal.ppat.1008560.
  • Timper K, Del Rio-Martin A, Cremer AL, Bremser S, Alber J, Giavalisco P, Varela L, Heilinger C, Nolte H, Trifunovic A, Horvath TL, Kloppenburg P, Backes H, and Bruning JC (2020). GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function. Cell Metab31, 1189-1205 e1113. doi:10.1016/j.cmet.2020.05.001.
  • Tonelli F, Cotti S, Leoni L, Besio R, Gioia R, Marchese L, Giorgetti S, Villani S, Gistelinck C, Wagener R, Kobbe B, Fiedler IAK, Larionova D, Busse B, Eyre D, Rossi A, Witten PE, and Forlino A (2020). Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype. Matrix Biol. doi:10.1016/j.matbio.2020.03.004.
  • Tong L, Wu PY, Phan JH, Hassazadeh HR, SEQC Consortium (including Fischer M), Tong W, Wang MD (2020). Impact of RNA-seq data analysis algorithms on gene expression estimation and downstream prediction. Sci Rep 10(1): 17925. doi: 10.1038/s41598-020-74567-y.
  • Tosetti B, Brodesser S, Brunn A, Deckert M, Bluher M, Doehner W, Anker SD, Wenzel D, Fleischmann B, Pongratz C, Peters F, Utermohlen O, and Kronke M (2020). A tissue-specific screen of ceramide expression in aged mice identifies ceramide synthase-1 and ceramide synthase-5 as potential regulators of fiber size and strength in skeletal muscle. Aging Cell19, e13049. doi:10.1111/acel.13049.
  • Trommer M, Kinsky J, Adams A, Hellmich M, Schlaak M, von Bergwelt-Baildon M, Celik E, Rosenbrock J, Morgenthaler J, Herter JM, Linde P, Mauch C, Theurich S, Marnitz S, and Baues C (2020). Addition of Radiotherapy to Immunotherapy: Effects on Outcome of Different Subgroups Using a Propensity Score Matching. Cancers (Basel)12. doi:10.3390/cancers12092429.
  • Trommer M, Yeo SY, Persigehl T, Bunck A, Grull H, Schlaak M, Theurich S, von Bergwelt-Baildon M, Morgenthaler J, Herter JM, Celik E, Marnitz S, and Baues C (2019). Corrigendum: Abscopal Effects in Radio-Immunotherapy-Response Analysis of Metastatic Cancer Patients With Progressive Disease Under Anti-PD-1 Immune Checkpoint Inhibition. Front Pharmacol10, 1615. doi:10.3389/fphar.2019.01615.
  • Trub M, Uhlenbrock F, Claus C, Herzig P, Thelen M, Karanikas V, Bacac M, Amann M, Albrecht R, Ferrara-Koller C, Thommen D, Rothschield S, Savic Prince S, Mertz KD, Cathomas G, Rosenberg R, Heinzelmann-Schwarz V, Wiese M, Lardinois D, Umana P, Klein C, Laubli H, Kashyap AS, and Zippelius A (2020). Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer. J Immunother Cancer8. doi:10.1136/jitc-2019-000238.
  • Tzaridis T, Reiners KS, Weller J, Bachurski D, Schafer N, Schaub C, Hallek M, Scheffler B, Glas M, Herrlinger U, Wild S, Coch C, and Hartmann G (2020). Analysis of Serum miRNA in Glioblastoma Patients: CD44-Based Enrichment of Extracellular Vesicles Enhances Specificity for the Prognostic Signature. Int J Mol Sci21. doi:10.3390/ijms21197211.
  • Ufartes R, Berger H, Till K, Salinas G, Sturm M, Altmuller J, Nurnberg P, Thiele H, Funke R, Apeshiotis N, Langen H, Wollnik B, Borchers A, and Pauli S (2020). De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome. Hum Genet. doi:10.1007/s00439-020-02175-x.
  • Unnersjo-Jess D, Butt L, Hohne M, Witasp A, Kuhne L, Hoyer PF, Patrakka J, Brinkkotter PT, Wernerson A, Schermer B, Benzing T, Scott L, Brismar H, and Blom H (2020). A Fast and Simple Clearing and Swelling Protocol for 3D In-Situ Imaging of the Kidney across Scales. Kidney Int. doi:10.1016/j.kint.2020.10.039.
  • van Schie MMCH, Kaczmarek AT, Tieves F, de Santos PG, Paul CE, Arends IWCE, Alcalde M, Schwarz G, and Hollmann F (2020). Selective Oxyfunctionalisation Reactions Driven by Sulfite Oxidase-Catalysed In Situ Generation of H2O2. Chemcatchem. doi:10.1002/cctc.201902297.
  • Verboom L, Martens A, Priem D, Hoste E, Sze M, Vikkula H, Van Hove L, Voet S, Roels J, Maelfait J, Bongiovanni L, de Bruin A, Scott CL, Saeys Y, Pasparakis M, Bertrand MJM, and van Loo G (2020). OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis. Cell Rep30, 2237-2247 e2236. doi:10.1016/j.celrep.2020.01.028.
  • Volker LA, Brinkkoetter PT, Knobl PN, Krstic M, Kaufeld J, Menne J, Buxhofer-Ausch V, and Miesbach W (2020). Treatment of acquired thrombotic thrombocytopenic purpura without plasma exchange in selected patients under caplacizumab. Journal of Thrombosis and Haemostasis18, 3061-3066. doi:10.1111/jth.15045.
  • Volker LA, Kaufeld J, Miesbach W, Brahler S, Reinhardt M, Kuhne L, Muhlfeld A, Schreiber A, Gaedeke J, Tolle M, Jabs WJ, Ozcan F, Markau S, Girndt M, Bauer F, Westhoff TH, Felten H, Hausberg M, Brand M, Gerth J, Bieringer M, Bommer M, Zschiedrich S, Schneider J, Elitok S, Gawlik A, Gackler A, Kribben A, Schwenger V, Schoenermarck U, Roeder M, Radermacher J, Bramstedt J, Morgner A, Herbst R, Harth A, Potthoff SA, von Auer C, Wendt R, Christ H, Brinkkoetter PT, and Menne J (2020). ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP. Blood Advances4, 3093-3101. doi:10.1182/bloodadvances.2020001987.
  • Volz C, Breid S, Selenz C, Zaplatina A, Golfmann K, Meder L, Dietlein F, Borchmann S, Chatterjee S, Siobal M, Schottle J, Florin A, Koker M, Nill M, Ozretic L, Uhlenbrock N, Smith S, Buttner R, Miao H, Wang B, Reinhardt HC, Rauh D, Hallek M, Acker-Palmer A, Heukamp LC, and Ullrich RT (2020). Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC. Cell Rep31, 107568. doi:10.1016/j.celrep.2020.107568.
  • von Amburen J, Schreiber F, Fischer J, Winter S, van Gumpel E, Simonis A, and Rybniker J (2020). Comprehensive Host Cell-Based Screening Assays for Identification of Anti-Virulence Drugs Targeting Pseudomonas aeruginosa and Salmonella Typhimurium. Microorganisms8. doi:10.3390/microorganisms8081096.
  • Wagener-Ryczek S, Schoemmel M, Kraemer M, Bruns C, Schroeder W, Zander T, Gebauer F, Alakus H, Merkelbach-Bruse S, Buettner R, Loeser H, Thelen M, Schlosser HA, and Quaas A (2020). Immune profile and immunosurveillance in treatment-naive and neoadjuvantly treated esophageal adenocarcinoma. Cancer Immunol Immunother69, 523-533. doi:10.1007/s00262-019-02475-w.
  • Walsh MB, Janzen E, Wingrove E, Hosseinibarkooie S, Muela NR, Davidow L, Dimitriadi M, Norabuena EM, Rubin LL, Wirth B, and Hart AC (2020). Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy. BMC Biol18, 127. doi:10.1186/s12915-020-00845-w.
  • Wang S, Meyer DH, and Schumacher B (2020). H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage. Nat Struct Mol Biol. doi:10.1038/s41594-020-00513-1.
  • Weglage J, Wolters F, Hehr L, Lichtenberger J, Wulz C, Hempel F, Baier A, Quack T, Kohler K, Longerich T, Schramm G, Irungbam K, Mueller H, von Buelow V, Tschuschner A, Odenthal M, Drebber U, Arousy ME, Ramalho LNZ, Bankov K, Wild P, Pons-Kuhnemann J, Tschammer J, Grevelding CG, Roeb E, and Roderfeld M (2020). Schistosoma mansoni eggs induce Wnt/beta-catenin signaling and activate the protooncogene c-Jun in human and hamster colon. Sci Rep10, 22373. doi:10.1038/s41598-020-79450-4.
  • Weiterer SS, Meier-Soelch J, Georgomanolis T, Mizi A, Beyerlein A, Weiser H, Brant L, Mayr-Buro C, Jurida L, Beuerlein K, Muller H, Weber A, Tenekeci U, Dittrich-Breiholz O, Bartkuhn M, Nist A, Stiewe T, van IWF, Riedlinger T, Schmitz ML, Papantonis A, and Kracht M (2020). Distinct IL-1alpha-responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner. EMBO J39, e101533. doi:10.15252/embj.2019101533.
  • Wicher D, Grenda R, Teisseyre M, Szymczak M, Halat-Wolska P, Jurkiewicz D, Liebau MC, Ciara E, Rydzanicz M, Kosinska J, Chrzanowska K, and Jankowska I (2020). Occurrence of Portal Hypertension and Its Clinical Course in Patients With Molecularly Confirmed Autosomal Recessive Polycystic Kidney Disease (ARPKD). Front Pediatr8, 591379. doi:10.3389/fped.2020.591379.
  • Witte L, Linnemannstons K, Schmidt K, Honemann-Capito M, Grawe F, Wodarz A, and Gross JC (2020). The kinesin motor Klp98A mediates apical to basal Wg transport. Development147. doi:10.1242/dev.186833.
  • Wolf A, Herb M, Schramm M, and Langmann T (2020). The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye. Nat Commun11, 2709. doi:10.1038/s41467-020-16400-8.
  • Wong J, Garcia-Carbonell R, Zelic M, Ho SB, Boland BS, Yao SJ, Desai SA, Das S, Planell N, Harris PA, Font-Burgada J, Taniguchi K, Bertin J, Salas A, Pasparakis M, Gough PJ, Kelliher M, Karin M, and Guma M (2020). RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-kappaB Activation. Cell Mol Gastroenterol Hepatol9, 295-312. doi:10.1016/j.jcmgh.2019.10.002.
  • Wuerdemann N, Jain R, Adams A, Speel EM, Wagner S, Joosse SA, and Klussmann JP (2020). Cell-Free HPV-DNA as a Biomarker for Oropharyngeal Squamous Cell Carcinoma-A Step Towards Personalized Medicine? Cancers (Basel)12. doi:10.3390/cancers12102997.
  • Wuerdemann N, Putz K, Eckel H, Jain R, Wittekindt C, Huebbers CU, Sharma SJ, Langer C, Gattenlohner S, Buttner R, Speel EJ, Suchan M, Wagner S, Quaas A, and Klussmann JP (2020). LAG-3, TIM-3 and VISTA Expression on Tumor-Infiltrating Lymphocytes in Oropharyngeal Squamous Cell Carcinoma-Potential Biomarkers for Targeted Therapy Concepts. Int J Mol Sci22. doi:10.3390/ijms22010379.
  • Wuerdemann N, Gultekin SE, Putz K, Wittekindt C, Huebbers CU, Sharma SJ, Eckel H, Schubotz AB, Gattenlohner S, Buttner R, Speel EJ, Klussmann JP, Wagner S, and Quaas A (2020). PD-L1 Expression and a High Tumor Infiltrate of CD8+ Lymphocytes Predict Outcome in Patients with Oropharyngeal Squamous Cells Carcinoma. Int J Mol Sci 21. doi:10.3390/ijms21155228.
  • Yang X, Leslie G, Doroszuk A, Schneider S, Allen J, Decker B, Dunning AM, Redman J, Scarth J, Plaskocinska I, Luccarini C, Shah M, Pooley K, Dorling L, Lee A, Adank MA, Adlard J, Aittomaki K, Andrulis IL, Ang P, Barwell J, Bernstein JL, Bobolis K, Borg A, Blomqvist C, Claes KBM, Concannon P, Cuggia A, Culver JO, Damiola F, de Pauw A, Diez O, Dolinsky JS, Domchek SM, Engel C, Evans DG, Fostira F, Garber J, Golmard L, Goode EL, Gruber SB, Hahnen E, Hake C, Heikkinen T, Hurley JE, Janavicius R, Kleibl Z, Kleiblova P, Konstantopoulou I, Kvist A, Laduca H, Lee ASG, Lesueur F, Maher ER, Mannermaa A, Manoukian S, McFarland R, McKinnon W, Meindl A, Metcalfe K, Mohd Taib NA, Moilanen J, Nathanson KL, Neuhausen S, Ng PS, Nguyen-Dumont T, Nielsen SM, Obermair F, Offit K, Olopade OI, Ottini L, Penkert J, Pylkas K, Radice P, Ramus SJ, Rudaitis V, Side L, Silva-Smith R, Silvestri V, Skytte AB, Slavin T, Soukupova J, Tondini C, Trainer AH, Unzeitig G, Usha L, van Overeem Hansen T, Whitworth J, Wood M, Yip CH, Yoon SY, Yussuf A, Zogopoulos G, Goldgar D, Hopper JL, Chenevix-Trench G, Pharoah P, George SHL, Balmana J, Houdayer C, James P, El-Haffaf Z, Ehrencrona H, Janatova M, Peterlongo P, Nevanlinna H, Schmutzler R, Teo SH, Robson M, Pal T, Couch F, Weitzel JN, Elliott A, Southey M, Winqvist R, Easton DF, Foulkes WD, Antoniou AC, and Tischkowitz M (2020). Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families. J Clin Oncol38, 674-685. doi:10.1200/JCO.19.01907.
  • Yang X, Song H, Leslie G, Engel C, Hahnen E, Auber B, Horvath J, Kast K, Niederacher D, Turnbull C, Houlston R, Hanson H, Loveday C, Dolinsky JS, LaDuca H, Ramus SJ, Menon U, Rosenthal AN, Jacobs I, Gayther SA, Dicks E, Nevanlinna H, Aittomaki K, Pelttari LM, Ehrencrona H, Borg A, Kvist A, Rivera B, Hansen TVO, Djursby M, Lee A, Dennis J, Bowtell DD, Traficante N, Diez O, Balmana J, Gruber SB, Chenevix-Trench G, kConFab I, Jensen A, Kjaer SK, Hogdall E, Castera L, Garber J, Janavicius R, Osorio A, Golmard L, Vega A, Couch FJ, Robson M, Gronwald J, Domchek SM, Culver JO, de la Hoya M, Easton DF, Foulkes WD, Tischkowitz M, Meindl A, Schmutzler RK, Pharoah PDP, and Antoniou AC (2020). Ovarian and breast cancer risks associated with pathogenic variants in RAD51C and RAD51D. J Natl Cancer Inst. doi:10.1093/jnci/djaa030.
  • Yigit G, Saida K, DeMarzo D, Miyake N, Fujita A, Yang Tan T, White SM, Wadley A, Toliat MR, Motameny S, Franitza M, Stutterd CA, Chong PF, Kira R, Sengoku T, Ogata K, Guillen Sacoto MJ, Fresen C, Beck BB, Nurnberg P, Dieterich C, Wollnik B, Matsumoto N, and Altmuller J (2020). The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype. Hum Mutat41, 591-599. doi:10.1002/humu.23964.
  • Zimmermann K, Kuehle J, Dragon AC, Galla M, Kloth C, Rudek LS, Sandalcioglu IE, Neyazi B, Moritz T, Meyer J, Rossig C, Altvater B, Eiz-Vesper B, Morgan MA, Abken H, and Schambach A (2020). Design and Characterization of an "All-in-One" Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines. Cancers (Basel)12. doi:10.3390/cancers12020375.
  • Zivna M, Kidd K, Zaidan M, Vyletal P, Baresova V, Hodanova K, Sovova J, Hartmannova H, Votruba M, Treslova H, Jedlickova I, Sikora J, Hulkova H, Robins V, Hnizda A, Zivny J, Papagregoriou G, Mesnard L, Beck BB, Wenzel A, Tory K, Haeffner K, Wolf MTF, Bleyer ME, Sayer JA, Ong ACM, Balogh L, Jakubowska A, Laszkiewicz A, Clissold R, Shaw-Smith C, Munshi R, Haws RM, Izzi C, Capelli I, Santostefano M, Graziano C, Scolari F, Sussman A, Trachtman H, Decramer S, Matignon M, Grimbert P, Shoemaker LR, Stavrou C, Abdelwahed M, Belghith N, Sinclair M, Claes K, Kopel T, Moe S, Deltas C, Knebelmann B, Rampoldi L, Kmoch S, and Bleyer AJ (2020). An International Cohort Study of Autosomal Dominant Tubulointerstitial Kidney Disease due to REN Mutations Identifies Distinct Clinical Subtypes. Kidney Int. doi:10.1016/j.kint.2020.06.041.
  • Annibaldi A, and Walczak H (2020). Death Receptors and Their Ligands in Inflammatory Disease and Cancer. Cold Spring Harb Perspect Biol. doi:10.1101/cshperspect.a036384.
  • Balaji V, and Hoppe T (2020). Regulation of E3 ubiquitin ligases by homotypic and heterotypic assembly. F1000Res9. doi:10.12688/f1000research.21253.1.
  • Behnke V, Wolf A, and Langmann T (2020). The role of lymphocytes and phagocytes in age-related macular degeneration (AMD). Cell Mol Life Sci77, 781-788. doi:10.1007/s00018-019-03419-4.
  • Bergami M, and Motori E (2020). Reweaving the Fabric of Mitochondrial Contact Sites in Astrocytes. Front Cell Dev Biol8, 592651. doi:10.3389/fcell.2020.592651.
  • Bhargava R, Fischer M, and O'Sullivan RJ (2020). Genome rearrangements associated with aberrant telomere maintenance. Curr Opin Genet Dev60, 31-40. doi:10.1016/j.gde.2020.02.005.
  • Braun T, von Jan J, Wahnschaffe L, and Herling M (2020). Advances and Perspectives in the Treatment of T-PLL. Curr Hematol Malig Rep15, 113-124. doi:10.1007/s11899-020-00566-5.
  • Brockelmann PJ, de Jong MRW, and Jachimowicz RD (2020). Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma. Cells9. doi:10.3390/cells9102287.
  • Chatzidoukaki O, Goulielmaki E, Schumacher B, and Garinis GA (2020). DNA Damage Response and Metabolic Reprogramming in Health and Disease. Trends in Genetics36, 777-791. doi:10.1016/j.tig.2020.06.018.
  • Clahsen T, Buttner C, Hatami N, Reis A, and Cursiefen C (2020). Role of Endogenous Regulators of Hem- And Lymphangiogenesis in Corneal Transplantation. J Clin Med9. doi:10.3390/jcm9020479.
  • Deshwal S, Fiedler KU, and Langer T (2020). Mitochondrial Proteases: Multifaceted Regulators of Mitochondrial Plasticity. Annu Rev Biochem89, 501-528. doi:10.1146/annurev-biochem-062917-012739.
  • Escobar-Henriques M, Altin S, and Brave FD (2020). Interplay between the Ubiquitin Proteasome System and Mitochondria for Protein Homeostasis. Curr Issues Mol Biol35, 35-58. doi:10.21775/cimb.035.035.
  • Escobar-Henriques M, and Anton V (2020). Mitochondrial Surveillance by Cdc48/p97: MAD vs. Membrane Fusion. Int J Mol Sci21. doi:10.3390/ijms21186841.
  • Etich J, Rehberg M, Eckes B, Sengle G, Semler O, and Zaucke F (2020). Signaling pathways affected by mutations causing osteogenesis imperfecta. Cell Signal76, 109789. doi:10.1016/j.cellsig.2020.109789.
  • Flumann R, Nieper P, Reinhardt HC, and Knittel G (2020). New murine models of aggressive lymphoma. Leuk Lymphoma61, 788-798. doi:10.1080/10428194.2019.1691200.
  • Gebel J, Tuppi M, Sanger N, Schumacher B, and Dotsch V (2020). DNA Damaged Induced Cell Death in Oocytes. Molecules25. doi:10.3390/molecules25235714.
  • Green KJ, Roth-Carter Q, Niessen CM, and Nichols SA (2020). Tracing the Evolutionary Origin of Desmosomes. Curr Biol30, R535-R543. doi:10.1016/j.cub.2020.03.047.
  • Gries R, Sala C, and Rybniker J (2020). Host-Directed Therapies and Anti-Virulence Compounds to Address Anti-Microbial Resistant Tuberculosis Infection. Applied Sciences-Basel10. doi:ARTN 2688 10.3390/app10082688.
  • Hansen HP, Paes Leme AF, and Hallek M (2020). Role of ADAM10 as a CD30 Sheddase in Classical Hodgkin Lymphoma. Front Immunol11, 398. doi:10.3389/fimmu.2020.00398.
  • Haumann S, Muller RU, and Liebau MC (2020). Metabolic Changes in Polycystic Kidney Disease as a Potential Target for Systemic Treatment. Int J Mol Sci 21. doi:10.3390/ijms21176093.
  • Hoppe T, and Cohen E (2020). Organismal Protein Homeostasis Mechanisms. Genetics215, 889-901. doi:10.1534/genetics.120.301283.
  • Janoschek R, Hoffmann T, Morcos YAT, Sengle G, Dotsch J, and Hucklenbruch-Rother E (2020). Asprosin in pregnancy and childhood. Mol Cell Pediatr7, 18. doi:10.1186/s40348-020-00110-8.
  • Joaquim M, and Escobar-Henriques M (2020). Role of Mitofusins and Mitophagy in Life or Death Decisions. Front Cell Dev Biol8, 572182. doi:10.3389/fcell.2020.572182.
  • Kinuthia UM, Wolf A, Langmann T (2020). Microglia and Inflammatory Responses in diabetic Retinopathy. Front Immunol 11:564077
  • Korner RW, Majjouti M, Alcazar MAA, and Mahabir E (2020). Of Mice and Men: The Coronavirus MHV and Mouse Models as a Translational Approach to Understand SARS-CoV-2. Viruses12. doi:10.3390/v12080880.
  • Kreer C, Gruell H, Mora T, Walczak AM, and Klein F (2020). Exploiting B Cell Receptor Analyses to Inform on HIV-1 Vaccination Strategies. Vaccines (Basel)8. doi:10.3390/vaccines8010013.
  • Llamas E, Alirzayeva H, Loureiro R, and D. Vilchez (2020). The intrinsic proteostasis network of stem cells. Current Opinion in Cell Biology 67: 46-55.
  • Malin JJ, Suarez I, Priesner V, Fatkenheuer G, and Rybniker J (2020). Remdesivir against COVID-19 and Other Viral Diseases. Clin Microbiol Rev34. doi:10.1128/CMR.00162-20.
  • Moreno L, Barone G, DuBois SG, Molenaar J, Fischer M, Schulte J, Eggert A, Schleiermacher G, Speleman F, Chesler L, Geoerger B, Hogarty MD, Irwin MS, Bird N, Blanchard GB, Buckland S, Caron H, Davis S, De Wilde B, Deubzer HE, Dolman E, Eilers M, George RE, George S, Jaroslav S, Maris JM, Marshall L, Merchant M, Mortimer P, Owens C, Philpott A, Poon E, Shay JW, Tonelli R, Valteau-Couanet D, Vassal G, Park JR, and Pearson ADJ (2020). Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma. Eur J Cancer136, 52-68. doi:10.1016/j.ejca.2020.05.010.
  • Muller RU, and Schermer B (2020). Hippo signaling-a central player in cystic kidney disease? Pediatr Nephrol35, 1143-1152. doi:10.1007/s00467-019-04299-3.
  • Poirier JT, George J, Owonikoko TK, Berns A, Brambilla E, Byers LA, Carbone D, Chen HJ, Christensen CL, Dive C, Farago AF, Govindan R, Hann C, Hellmann MD, Horn L, Johnson JE, Ju YS, Kang S, Krasnow M, Lee J, Lee SH, Lehman J, Lok B, Lovly C, MacPherson D, McFadden D, Minna J, Oser M, Park K, Park KS, Pommier Y, Quaranta V, Ready N, Sage J, Scagliotti G, Sos ML, Sutherland KD, Travis WD, Vakoc CR, Wait SJ, Wistuba I, Wong KK, Zhang H, Daigneault J, Wiens J, Rudin CM, and Oliver TG (2020). New Approaches to SCLC Therapy: From the Laboratory to the Clinic. J Thorac Oncol15, 520-540. doi:10.1016/j.jtho.2020.01.016.
  • Ravanelli S, den Brave F, and Hoppe T (2020). Mitochondrial Quality Control Governed by Ubiquitin. Front Cell Dev Biol8, 270. doi:10.3389/fcell.2020.00270.
  • Sachinidis A (2020). Cardiotoxicity and Heart Failure: Lessons from Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Anticancer Drugs. Cells9. doi:10.3390/cells9041001.
  • Sanchez-Gaya V, Mariner-Fauli M, and Rada-Iglesias A (2020). Rare or Overlooked? Structural Disruption of Regulatory Domains in Human Neurocristopathies. Front Genet11, 688. doi:10.3389/fgene.2020.00688.
  • Schonberg A, Hamdorf M, and Bock F (2020). Immunomodulatory Strategies Targeting Dendritic Cells to Improve Corneal Graft Survival. J Clin Med9. doi:10.3390/jcm9051280.
  • Schwarzer R, Laurien L, and Pasparakis M (2020). New insights into the regulation of apoptosis, necroptosis, and pyroptosis by receptor interacting protein kinase 1 and caspase-8. Curr Opin Cell Biol63, 186-193. doi:10.1016/j.ceb.2020.02.004.
  • Spath MR, Koehler FC, Hoyer-Allo KJR, Grundmann F, Burst V, and Muller RU (2020). Preconditioning strategies to prevent acute kidney injury. F1000Res9. doi:10.12688/f1000research.21406.1.
  • Stecher M, Classen A, Klein F, Lehmann C, Gruell H, Platten M, Wyen C, Behrens G, Fatkenheuer G, and Vehreschild JJ (2020). Systematic Review and Meta-analysis of Treatment Interruptions in Human Immunodeficiency Virus (HIV) Type 1-infected Patients Receiving Antiretroviral Therapy: Implications for Future HIV Cure Trials. Clin Infect Dis70, 1406-1417. doi:10.1093/cid/ciz417.
  • Strubl S, Torres JA, Spindt AK, Pellegrini H, Liebau MC, and Weimbs T (2020). STAT signaling in polycystic kidney disease. Cell Signal72, 109639. doi:10.1016/j.cellsig.2020.109639.
  • Turpin-Nolan SM, and Bruning JC (2020). The role of ceramides in metabolic disorders: when size and localization matters. Nat Rev Endocrinol16, 224-233. doi:10.1038/s41574-020-0320-5.
  • von Karstedt S, and Walczak H (2020). An unexpected turn of fortune: targeting TRAIL-Rs in KRAS-driven cancer. Cell Death Discov6, 14. doi:10.1038/s41420-020-0249-4.
  • Wirth B, Karakaya M, Kye MJ, and Mendoza-Ferreira N (2020). Twenty-Five Years of Spinal Muscular Atrophy Research: From Phenotype to Genotype to Therapy, and What Comes Next. Annu Rev Genomics Hum Genet. doi:10.1146/annurev-genom-102319-103602.
  • Wu F, Fan J, Fang J, Dalvi PS, Odenthal M, and Fang N (2020). Single Cell Sequencing: A New Dimension in Cancer Diagnosis and Treatment. Adv Exp Med Biol 1255, 109-121. doi:10.1007/978-981-15-4494-1_9.
  • Zhao Y, Li J, Li D, Wang Z, Zhao J, Wu X, Sun Q, Lin PP, Plum P, Damanakis A, Gebauer F, Zhou M, Zhang Z, Schlosser H, Jauch KW, Nelson PJ, and Bruns CJ (2020). Tumor biology and multidisciplinary strategies of oligometastasis in gastrointestinal cancers. Semin Cancer Biol60, 334-343. doi:10.1016/j.semcancer.2019.08.026.
  • Zhou C, Fan N, Liu F, Fang N, Plum PS, Thieme R, Gockel I, Gromnitza S, Hillmer AM, Chon SH, Schlosser HA, Bruns CJ, and Zhao Y (2020). Linking Cancer Stem Cell Plasticity to Therapeutic Resistance-Mechanism and Novel Therapeutic Strategies in Esophageal Cancer. Cells9. doi:10.3390/cells9061481.

Discover more:

 
University of Cologne (Universtität zu Köln)
Faculty of Medicine Faculty of Mathematics
and Natural Sciences
University Hospital of Cologne (Universitätsklinik zu Köln)

Copyright ©
Prof. Dr. med. Thomas Benzing
Chair of the CMMC