Summary of articles published by CMMC members in 2015
Selected publications related to CMMC-projects are listed in alphabetical order by the first author published in 2015.
Abdallah AT, Fischer M, Nurnberg P, Nothnagel M, and Frommolt P (2015). Concos: Copy number estimation in cancer with controlled support. J Bioinform Comput Biol 13, 1550027.
Abken H (2015). Adoptive therapy with car redirected t cells: The challenges in targeting solid tumors. Immunotherapy 7, 535-544.
Arjune S, Schwarz G, and Belaidi AA (2015). Involvement of the cys-tyr cofactor on iron binding in the active site of human cysteine dioxygenase. Amino Acids 47, 55-63.
Baris OR, Ederer S, Neuhaus JF, von Kleist-Retzow JC, Wunderlich CM, Pal M, Wunderlich FT, Peeva V, Zsurka G, Kunz WS, Hickethier T, Bunck AC, Stockigt F, Schrickel JW, and Wiesner RJ (2015). Mosaic deficiency in mitochondrial oxidative metabolism promotes cardiac arrhythmia during aging. Cell Metab 21, 667-677.
Bartram MP, Dafinger C, Habbig S, Benzing T, Schermer B, and Mueller RU (2015). Loss of Dgcr8-mediated microRNA expression in the kidney results in hydronephrosis and renal malformation. BMC Nephrol 16, 55.
Becker AK, Mikolajek H, Werner JM, Paulsson M, and Wagener R (2015). Characterization of recombinantly expressed matrilin vwa domains. Protein Expr Purif 107, 20-28.
Belaidi AA, Roper J, Arjune S, Krizowski S, Trifunovic A, and Schwarz G (2015). Oxygen reactivity of mammalian sulfite oxidase provides a concept for the treatment of sulfite oxidase deficiency. Biochem J 469, 211-221.
Beleggia F, Li Y, Fan J, Elcioglu NH, Toker E, Wieland T, Maumenee IH, Akarsu NA, Meitinger T, Strom TM, Lang R, and Wollnik B (2015). Crim1 haploinsufficiency causes defects in eye development in human and mouse. Hum Mol Genet 24, 2267-2273.
Benzing T (2015). Polycystic kidney disease. HALTing PKD progression--revival of blood pressure control. Nat Rev Nephrol 11, 129-131.
Blein S, Bardel C, Danjean V, McGuffog L, Healey S, Barrowdale D, Lee A, Dennis J, Schmutzler RK, et al. , Antoniou AC, Mazoyer S, Phelan CM, Sinilnikova OM, and Cox DG (2015). An original phylogenetic approach identified mitochondrial haplogroup t1a1 as inversely associated with breast cancer risk in brca2 mutation carriers. Breast Cancer Res 17, 61.
Bobylev I, Joshi AR, Barham M, Ritter C, Neiss WF, Hoke A, and Lehmann HC (2015). Paclitaxel inhibits mrna transport in axons. Neurobiol Dis 82, 321-331.
Bogershausen N, Tsai IC, Pohl E, Kiper PO, Beleggia F, Percin EF, Keupp K, Matchan A, Milz E, Alanay Y, Kayserili H, Liu Y, Banka S, Kranz A, Zenker M, Wieczorek D, Elcioglu N, Prontera P, Lyonnet S, Meitinger T, Stewart AF, Donnai D, Strom TM, Boduroglu K, Yigit G, Li Y, Katsanis N, and Wollnik B (2015). Rap1-mediated mek/erk pathway defects in kabuki syndrome. J Clin Invest 125, 3585-3599.
Boucas J, Fritz C, Schmitt A, Riabinska A, Thelen L, Peifer M, Leeser U, Nuernberg P, Altmueller J, Gaestel M, Dieterich C, and Reinhardt HC (2015). Label-free protein-rna interactome analysis identifies khsrp signaling downstream of the p38/mk2 kinase complex as a critical modulator of cell cycle progression. PLoS One 10, e0125745.
Brahler S, Ising C, Barrera Aranda B, Hohne M, Schermer B, Benzing T, and Brinkkoetter PT (2015). The NF-?B essential modulator (NEMO) controls podocyte cytoskeletal dynamics independently of NF-?B. Am J Physiol Renal Physiol 309, F617-626.
Bramswig NC, Ludecke HJ, Alanay Y, Albrecht B, Barthelmie A, Boduroglu K, Braunholz D, Caliebe A, Chrzanowska KH, Czeschik JC, Endele S, Graf E, Guillen-Navarro E, Kiper PO, Lopez-Gonzalez V, Parenti I, Pozojevic J, Utine GE, Wieland T, Kaiser FJ, Wollnik B, Strom TM, and Wieczorek D (2015). Exome sequencing unravels unexpected differential diagnoses in individuals with the tentative diagnosis of coffin-siris and nicolaides-baraitser syndromes. Hum Genet 134, 553-568.
Brant L, and Papantonis A (2015). Contribution of 3D chromatin architecture to the maintenance of pluripotency. Curr Stem Cell Rep 1, 1-6.
Brinkmann K, Schell M, Hoppe T*, and Kashkar H* (2015). Regulation of the DNA damage response by ubiquitin conjugation. Front Genet 6, 98.
Bruns M, Wanger J, Utermoehlen O, and Deppert W (2015). An inducible transgenic mouse breast cancer model for the analysis of tumor antigen specific cd8+ t-cell responses. Oncotarget 6, 38487-38503.
Buchholz CJ, Friedel T, and Buening H (2015). Surface-engineered viral vectors for selective and cell type-specific gene delivery. Trends Biotechnol 10.1016/j.tibtech.2015.09.008.
Buening H, Huber A, Zhang L, Meumann N, and Hacker U (2015). Engineering the aav capsid to optimize vector-host-interactions. Curr Opin Pharmacol 24, 94-104.
Bultmann-Mellin I, Conradi A, Maul AC, Dinger K, Wempe F, Wohl AP, Imhof T, Wunderlich FT, Bunck AC, Nakamura T, Koli K, Bloch W, Ghanem A, Heinz A, von Melchner H, Sengle G, and Sterner-Kock A (2015). Modeling autosomal recessive cutis laxa type 1c (arcl1c) in mice reveals distinct functions of ltbp-4 isoforms. Dis Model Mech 8, 403-15.
Castori M, Pascolini G, Parisi V, Sana ME, Novelli A, Nurnberg P, Iascone M, and Grammatico P (2015). Microcephaly, ectodermal dysplasia, multiple skeletal anomalies, and distinctive facial appearance: Delineation of cerebro-dermato-osseous-dysplasia. Am J Med Genet Part A 167A, 842-851.
Caudron-Herger M, Cook PR, Rippe K, and Papantonis A (2015). Dissecting the nascent human transcriptome by analysing the rna content of transcription factories. Nucleic Acids Res 43, e9.
Chaudhari U, Nemade H, Wagh V, Gaspar JA, Ellis JK, Srinivasan SP, Spitkovski D, Nguemo F, Louisse J, Bremer S, Hescheler J, Keun HC, Hengstler JG, and Sachinidis A (2015). Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human ipsc-derived cardiomyocytes: An in vitro repeated exposure toxicity approach for safety assessment. Arch Toxicol 10.1007/s00204-015-1623-5.
Chi JC, Roeper J, Schwarz G, and Fischer-Schrader K (2015). Dual binding of 14-3-3 protein regulates arabidopsis nitrate reductase activity. J Biol Inorg Chem 20, 277-286.
Chmielewski M, and Abken H (2015). Trucks: The fourth generation of cars. Expert Opin Biol Ther 15, 1145-1154.
Chong AC, Vogt MC, Hill AS, Bruening JC, and Zeltser LM (2015). Central insulin signaling modulates hypothalamus-pituitary-adrenal axis responsiveness. Mol Metab 4, 83-92.
Coutelle O, Schiffmann LM, Liwschitz M, Brunold M, Goede V, Hallek M, Kashkar H*, and Hacker UT* (2015). Dual targeting of angiopoetin-2 and vegf potentiates effective vascular normalisation without inducing empty basement membrane sleeves in xenograft tumours. Br J Cancer 112, 495-503.
Curtis J, Luo Y, Zenner HL, Cuchet-Lourenco D, Wu CX, Lo K, Maes M, Alisaac A, Stebbings E, Liu JZ, Kopanitsa L, Ignatyeva O, Balabanova Y, Nikolayevskyy V, Baessmann I, Thye T, Meyer CG, Nurnberg P, Horstmann RD, Drobniewski F, Plagnol V, Barrett JC, and Nejentsev S (2015). Susceptibility to tuberculosis is associated with variants in the asap1 gene encoding a regulator of dendritic cell migration. Nature Genetics 47, 523-U128.
Dannhausen K, Karlstetter M, Caramoy A, Volz C, Jagle H, Liebisch G, Utermoehlen O, and Langmann T (2015). Acid sphingomyelinase (asmase) deficiency leads to abnormal microglia behavior and disturbed retinal function. Biochem Biophys Res Commun 464, 434-440.
Darabi H, McCue K, Beesley J, Michailidou K, Nord S, Kar S, Humphreys K, Thompson D, et al., Schmutzler RK, et al. , Kristensen V, French JD, Edwards SL, Dunning AM, Easton DF, Hall P, and Chenevix-Trench G (2015). Polymorphisms in a putative enhancer at the 10q21.2 breast cancer risk locus regulate nrbf2 expression. Am J Hum Genet 97, 22-34.
Deckstein J, van Appeldorn J, Tsangarides M, Yiannakou K, Muller R, Stumpf M, Sukumaran SK, Eichinger L, Noegel AA, and Riyahi TY (2015). The dictyostelium discoideum gphr ortholog is an endoplasmic reticulum and golgi protein with roles during development. Eukaryot Cell 14, 41-54.
Dejanovic B, Djemie T, Grunewald N, Suls A, Kress V, Hetsch F, Craiu D, Zemel M, Gormley P, Lal D, Myers CT, Mefford HC, Palotie A, Helbig I, Meier JC, De Jonghe P, Weckhuysen S, and Schwarz G (2015). Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy. EMBO Mol Med 7, 1580-94.
Diener Y, Jurk M, Kandil B, Choi YH, Wild S, Bissels U, and Bosio A (2015). Rna-based, transient modulation of gene expression in human haematopoietic stem and progenitor cells. Sci Rep 5, 17184.
Duffy DJ, Krstic A, Halasz M, Schwarzl T, Fey D, Iljin K, Mehta JP, Killick K, Whilde J, Turriziani B, Haapa-Paananen S, Fey V, Fischer M, Westermann F, Henrich KO, Bannert S, Higgins DG, and Kolch W (2015). Integrative omics reveals mycn as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma. Oncotarget 6, 43182-201.
Ebner K, Feldkoetter M, Ariceta G, Bergmann C, Buettner R, Doyon A, Duzova A, Goebel H, Haffner D, Hero B, Hoppe B, Illig T, Jankauskiene A, Klopp N, Konig J, Litwin M, Mekahli D, Ranchin B, Sander A, Testa S, Weber LT, Wicher D, Yuzbasioglu A, Zerres K, Dotsch J, Schaefer F, Liebau MC, Group ES, and Group GPNS (2015). Rationale, design and objectives of aregpkd, a european arpkd registry study. BMC Nephrol 16, 22.
Edifizi D, and Schumacher B (2015). Genome instability in development and aging: Insights from nucleotide excision repair in humans, mice, and worms. Biomolecules 5, 1855-1869.
Elsayed SM, Phillips JB, Heller R, Thoenes M, Elsobky E, Nurnberg G, Nurnberg P, Seland S, Ebermann I, Altmuller J, Thiele H, Toliat M, Korber F, Hu XJ, Wu YD, Zaki MS, Abdel-Salam G, Gleeson J, Boltshauser E, Westerfield M, and Bolz HJ (2015). Non-manifesting ahi1 truncations indicate localized loss-of-function tolerance in a severe mendelian disease gene. Hum Mol Genet 24, 2594-2603.
Erny D, Hrabe de Angelis AL, Jaitin D, Wieghofer P, Staszewski O, David E, Keren-Shaul H, Mahlakoiv T, Jakobshagen K, Buch T, Schwierzeck V, Utermoehlen O, Chun E, Garrett WS, McCoy KD, Diefenbach A, Staeheli P, Stecher B, Amit I, and Prinz M (2015). Host microbiota constantly control maturation and function of microglia in the cns. Nat Neurosci 18, 965-977.
Fernandez-Cuesta L, Sun R, Menon R, George J, Lorenz S, Meza-Zepeda LA, Peifer M, Plenker D, Heuckmann JM, Leenders F, Zander T, Dahmen I, Koker M, Schottle J, Ullrich RT, Altmuller J, Becker C, Nurnberg P, Seidel H, Bohm D, Goke F, Ansen S, Russell PA, Wright GM, Wainer Z, Solomon B, Petersen I, Clement JH, Sanger J, Brustugun OT, Helland A, Solberg S, Lund-Iversen M, Buettner R, Wolf J, Brambilla E, Vingron M, Perner S, Haas SA, and Thomas RK (2015). Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data. Genome Biol 16, 7.
Fey D, Halasz M, Dreidax D, Kennedy SP, Hastings JF, Rauch N, Munoz AG, Pilkington R, Fischer M, Westermann F, Kolch W, Kholodenko BN, and Croucher DR (2015). Signaling pathway models as biomarkers: Patient-specific simulations of jnk activity predict the survival of neuroblastoma patients. Sci Signal 8, ra130.
Forster A, Grotha SP, Seeger JM, Rabenhorst A, Gehring M, Raap U, Letard S, Dubreuil P, Kashkar H, Walczak H, Roers A, and Hartmann K (2015). Activation of kit modulates the function of tumor necrosis factor-related apoptosis-inducing ligand receptor (trail-r) in mast cells. Allergy 70, 764-74.
Frances D, Sharma N, Pofahl R, Maneck M, Behrendt K, Reuter K, Krieg T, Klein CA, Haase I, and Niemann C (2015). A role for rac1 activity in malignant progression of sebaceous skin tumors. Oncogene 34, 5505-12.
Freudenberg U, Zieris A, Chwalek K, Tsurkan MV, Maitz MF, Atallah P, Levental KR, Eming SA, and Werner C (2015). Heparin desulfation modulates vegf release and angiogenesis in diabetic wounds. J Control Release 220, 79-88.
Freund NT, Horwitz JA, Nogueira L, Sievers SA, Scharf L, Scheid JF, Gazumyan A, Liu C, Velinzon K, Goldenthal A, Sanders RW, Moore JP, Bjorkman PJ, Seaman MS, Walker BD, Klein F, and Nussenzweig MC (2015). A new glycan-dependent cd4-binding site neutralizing antibody exerts pressure on hiv-1 in vivo. PLoS Pathog 11, e1005238.
Friedel T, Hanisch LJ, Muth A, Honegger A, Abken H, Pluckthun A, Buchholz CJ, and Schneider IC (2015). Receptor-targeted lentiviral vectors are exceptionally sensitive toward the biophysical properties of the displayed single-chain fv. Protein Eng Des Sel 28, 93-106.
Frommolt P, and Schumacher B (2015). Wormpath: Searching for molecular interaction networks in caenorhabditis elegans. Source Code Biol Med 10, 5.
Gabdoulline R, Kaisers W, Gaspar A, Meganathan K, Doss MX, Jagtap S, Hescheler J, Sachinidis A, and Schwender H (2015). Differences in the early development of human and mouse embryonic stem cells. PLoS One 10, e0140803.
Garbes L, Kim K, Riess A, Hoyer-Kuhn H, Beleggia F, Bevot A, Kim MJ, Huh YH, Kweon HS, Savarirayan R, Amor D, Kakadia PM, Lindig T, Kagan KO, Becker J, Boyadjiev SA, Wollnik B, Semler O, Bohlander SK, Kim J, and Netzer C (2015). Mutations in sec24d, encoding a component of the copii machinery, cause a syndromic form of osteogenesis imperfecta. Am J Hum Genet 96, 432-439.
George J, Lim JS, Jang SJ, Cun Y, Ozretic L, Kong G, Leenders F, Lu X, Fernandez-Cuesta L, Bosco G, Muller C, Dahmen I, Jahchan NS, Park KS, Yang D, Karnezis AN, Vaka D, Torres A, Wang MS, Korbel JO, Menon R, Chun SM, Kim D, Wilkerson M, Hayes N, Engelmann D, Putzer B, Bos M, Michels S, Vlasic I, Seidel D, Pinther B, Schaub P, Becker C, Altmuller J, Yokota J, Kohno T, Iwakawa R, Tsuta K, Noguchi M, Muley T, Hoffmann H, Schnabel PA, Petersen I, Chen Y, Soltermann A, Tischler V, Choi CM, Kim YH, Massion PP, Zou Y, Jovanovic D, Kontic M, Wright GM, Russell PA, Solomon B, Koch I, Lindner M, Muscarella LA, la Torre A, Field JK, Jakopovic M, Knezevic J, Castanos-Velez E, Roz L, Pastorino U, Brustugun OT, Lund-Iversen M, Thunnissen E, Kohler J, Schuler M, Botling J, Sandelin M, Sanchez-Cespedes M, Salvesen HB, Achter V, Lang U, Bogus M, Schneider PM, Zander T, Ansen S, Hallek M, Wolf J, Vingron M, Yatabe Y, Travis WD, Nurnberg P, Reinhardt C, Perner S, Heukamp L, Buettner R, Haas SA, Brambilla E, Peifer M, Sage J, and Thomas RK (2015). Comprehensive genomic profiles of small cell lung cancer. Nature 524, 47-53.
Giampietro C, Disanza A, Bravi L, Barrios-Rodiles M, Corada M, Frittoli E, Savorani C, Lampugnani MG, Boggetti B, Niessen C, Wrana JL, Scita G, and Dejana E (2015). The actin-binding protein eps8 binds ve-cadherin and modulates yap localization and signaling. Journal of Cell Biology 211, 1177-1192.
Giannopoulou EZ, Martin T, Wirth B, Yilmaz U, Gortner L, and Meyer S (2015). Tongue fasciculations in an infant with spinal muscular atrophy type 1. Clin Case Rep 3, 832-834.
Glubb DM, Maranian MJ, Michailidou K, Pooley KA, Meyer KB, Kar S, Carlebur S, et al., Schmutzler RK, et al., Thompson DJ, Edwards SL, Easton DF, Dunning AM, and French JD (2015). Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating map3k1. Am J Hum Genet 96, 5-20.
Godoy P, Schmidt-Heck W, Natarajan K, Lucendo-Villarin B, Szkolnicka D, Asplund A, Bjorquist P, Widera A, Stoeber R, Campos G, Hammad S, Sachinidis A, Damm G, Weiss TS, Nussler A, Synnergren J, Edlund K, Kuppers-Munther B, Hay D, and Hengstler JG (2015). Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells. J Hepatol 63, 934-42.
Gollasch B, Basmanav FB, Nanda A, Fritz G, Mahmoudi H, Thiele H, Wehner M, Wolf S, Altmuller J, Nurnberg P, Frank J, and Betz RC (2015). Identification of a novel mutation in ripk4 in a kindred with phenotypic features of bartsocas-papas and chand syndromes. Am J Med Genet A 167, 2555-2562.
Grunewald I, Vollbrecht C, Meinrath J, Meyer MF, Heukamp LC, Drebber U, Quaas A, Beutner D, Huttenbrink KB, Wardelmann E, Hartmann W, Buettner R, Odenthal M, and Stenner M (2015). Targeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity. Oncotarget 6, 18224-18237.
Guo X, Long J, Zeng C, Michailidou K, Ghoussaini M, Bolla MK, Wang Q, Milne RL, Shu XO, et al., Schmutzler RK, et al., Pharoah PD, Simard J, Chenevix-Trench G, Dunning AM, Easton DF, and Zheng W (2015). Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk. Cancer Epidemiol Biomarkers Prev 24, 1680-1691.
Habbig S, and Liebau MC (2015). Ciliopathies - from rare inherited cystic kidney diseases to basic cellular function. Mol Cell Pediatr 2, 8.
Hagmann H, and Brinkkoetter PT (2015). Ros and oxidative stress in ckd patients: Is it the mitochondria that keeps ckd patients in bed? Nephrol Dial Transplant 30, 867-868.
Hagmann H, Taniguchi Y, Pippin JW, Kauerz HM, Benzing T, Shankland SJ, and Brinkkoetter PT (2015). Cyclin I and p35 determine the subcellular distribution of Cdk5. Am J Physiol Cell Physiol 308, C339-347.
Hardies K, de Kovel CG, Weckhuysen S, Asselbergh B, Geuens T, Deconinck T, Azmi A, May P, Brilstra E, Becker F, Barisic N, Craiu D, Braun KP, Lal D, Thiele H, Schubert J, Weber Y, van 't Slot R, Nurnberg P, Balling R, Timmerman V, Lerche H, Maudsley S, Helbig I, Suls A, Koeleman BP, De Jonghe P, and autosomal recessive working group of the Euro ERESC (2015). Recessive mutations in slc13a5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia. Brain 138, 3238-3250.
Hedergott A, Volk AE, Herkenrath P, Thiele H, Fricke J, Altmuller J, Nurnberg P, Kubisch C, and Neugebauer A (2015). Clinical and genetic findings in a family with nmnat1-associated leber congenital amaurosis: Case report and review of the literature. Graefes Arch Clin Exp Ophthalmol 10.1007/s00417-015-3174-0.
Heilig J, Paulsson M, and Zaucke F (2015). Insulin-like growth factor 1 receptor (igf1r) signaling regulates osterix expression and cartilage matrix mineralization during endochondral ossification. Bone 83, 48-57.
Hempel M, Schmitz A, Winkler S, Kucukoglu O, Bruckner S, Niessen CM, and Christ B (2015). Pathological implications of cadherin zonation in mouse liver. Cell Mol Life Sci 72, 2599-2612.
Hintermann E, Bayer M, Pfeilschifter JM, Deak F, Kiss I, Paulsson M, and Christen U (2015). Upregulation of matrilin-2 expression in murine hepatic stellate cells during liver injury has no effect on fibrosis formation and resolution. Liver Int 35, 1265-1273.
Hubers A, Just W, Rosenbohm A, Muller K, Marroquin N, Goebel I, Hogel J, Thiele H, Altmuller J, Nurnberg P, Weishaupt JH, Kubisch C, Ludolph AC, and Volk AE (2015). De novo fus mutations are the most frequent genetic cause in early-onset german als patients. Neurobiol Aging 36, 3117 e3111-3116.
Huebbers CU, Adam AC, Preuss SF, Schiffer T, Schilder S, Guntinas-Lichius O, Schmidt M, Klussmann JP, and Wiesner RJ (2015). High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ss-f1-atpase subunit in head and neck squamous cell carcinoma. Oncotarget 6, 36172-36184.
Imhof T, Gruenewald N, Schwarz G, Noack MJ, and Koch M (2015). Modified amelogenin is a new and versatile nanomaterial for biomedical applications. Biotechnol Bioeng 10.1002/bit.25576.
Ising C, Koehler S, Brahler S, Merkwirth C, Hohne M, Baris OR, Hagmann H, Kann M, Fabretti F, Dafinger C, Bloch W, Schermer B, Linkermann A, Bruening JC, Kurschat CE, Mueller RU, Wiesner RJ, Langer T, Benzing T, and Brinkkoetter PT (2015). Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure. EMBO Mol Med 7, 275-287.
Jakobshagen K, Ward B, Baschuk N, Huss S, Brunn A, Malecki M, Fiolka M, Rappl G, Corogeanu D, Karow U, Schiller P, Abken H, Heukamp LC, Deckert M, Kroenke M, and Utermoehlen O (2015). Endogenous il10 alleviates the systemic antiviral cellular immune response and t cell-mediated immunopathology in select organs of acutely lcmv-infected mice. Am J Pathol 185, 3025-3038.
Joshi AR, Bobylev I, Zhang G, Sheikh KA, and Lehmann HC (2015). Inhibition of rho-kinase differentially affects axon regeneration of peripheral motor and sensory nerves. Exp Neurol 263, 28-38.
Kaczmarek A, Schneider S, Wirth B, and Riessland M (2015). Investigational therapies for the treatment of spinal muscular atrophy. Expert Opin Investig Drugs 10.1517/13543784.2015.1038341, 1-15.
Kakar N, Ahmad J, Morris-Rosendahl DJ, Altmuller J, Friedrich K, Barbi G, Nurnberg P, Kubisch C, Dobyns WB, and Borck G (2015). Stil mutation causes autosomal recessive microcephalic lobar holoprosencephaly. Human Genetics 134, 45-51.
Kalimuthu P, Fischer-Schrader K, Schwarz G, and Bernhardt PV (2015). A sensitive and stable amperometric nitrate biosensor employing arabidopsis thaliana nitrate reductase. J Biol Inorg Chem 20, 385-393.
Kann M, Bae E, Lenz MO, Li L, Trannguyen B, Schumacher VA, Taglienti ME, Bordeianou L, Hartwig S, Rinschen MM, Schermer B, Benzing T, Fan CM, and Kreidberg JA (2015). WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals. Development 142, 1254-1266.
Kann M, Ettou S, Jung YL, Lenz MO, Taglienti ME, Park PJ, Schermer B, Benzing T, and Kreidberg JA (2015). Genome-wide analysis of Wilms' tumor 1-controlled gene expression in podocytes reveals key regulatory mechanisms. J Am Soc Nephrol 26, 2097-2104.
Kehrein K, Schilling R, Moller-Hergt BV, Wurm CA, Jakobs S, Lamkemeyer T, Langer T, and Ott M (2015). Organization of mitochondrial gene expression in two distinct ribosome-containing assemblies. Cell Rep 10.1016/j.celrep.2015.01.012.
Kelkar P, Walter A, Papadopoulos S, Mross C, Munck M, Peche VS, and Noegel AA (2015). Nesprin-2 mediated nuclear trafficking and its clinical implications. Nucleus 6, 479-89.
Kelly S, Georgomanolis T, Zirkel A, Diermeier S, O'Reilly D, Murphy S, Langst G, Cook PR, and Papantonis A (2015). Splicing of many human genes involves sites embedded within introns. Nucleic Acids Res 43, 4721-4732.
Kelly S, Greenman C, Cook PR, and Papantonis A (2015). Exon skipping is correlated with exon circularization. J Mol Biol 427, 2414-7.
Ketscher L, Hannss R, Morales DJ, Basters A, Guerra S, Goldmann T, Hausmann A, Prinz M, Naumann R, Pekosz A, Utermoehlen O, Lenschow DJ, and Knobeloch KP (2015). Selective inactivation of usp18 isopeptidase activity in vivo enhances isg15 conjugation and viral resistance. Proc Natl Acad Sci U S A 112, 1577-1582.
Kilic E, Yigit G, Utine GE, Wollnik B, Mihci E, Nur BG, and Boduroglu K (2015). A novel mutation in rnu4atac in a patient with microcephalic osteodysplastic primordial dwarfism type i. Am J Med Genet A 167A, 919-921.
Kloepper JE*, Baris OR*, Reuter K*, Kobayashi K, Weiland D, Vidali S, Tobin DJ, Niemann C, Wiesner RJ#, and Paus R (2015). Mitochondrial function in murine skin epithelium is crucial for hair follicle morphogenesis and epithelial-mesenchymal interactions. J Invest Dermatol 135, 679-689.
Knipper JA, Willenborg S, Brinckmann J, Bloch W, Maass T, Wagener R, Krieg T, Sutherland T, Munitz A, Rothenberg ME, Niehoff A, Richardson R, Hammerschmidt M, Allen JE, and Eming SA (2015). Interleukin-4 receptor alpha signaling in myeloid cells controls collagen fibril assembly in skin repair. Immunity 43, 803-816.
Knuever J, Willenborg S, Ding X, Akyuz MD, Partridge L, Niessen CM, Bruening JC, and Eming SA (2015). Myeloid cell-restricted insulin/igf-1 receptor deficiency protects against skin inflammation. J Immunol 195, 5296-308
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