Maleki, Hajar - assoc. JRG 08 and CAP 35
Functional Bio-inspired Porous Materials
PD Dr. Hajar Maleki
Institute of Inorganic Chemistry
CMMC - PI - assoc. JRG 08 and CAP 35
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Institute of Inorganic Chemistry
Greinstr. 6
50939 Cologne
Introduction
Dr. Maleki's group focuses on the rational design of self-assembled and sol-gel derived bio-inspired hybrid smart nanomaterials as a theragenerative systems (combination of therapy and regeneration) with improved biomimetic microstructure, mechanical, self-healing and shape morphing properties for minimally invasive bone cancer therapy and bone regeneration and drug delivery purposes.
In our research we are specifically interested in designing biomaterials (hydrogels, and aerogels) with smart multifunctional properties through hybridization of self-assembled biopolymer with various surface engineered nanoparticles through the most advanced state-of-the-art synthesis and fabrication techniques like 3D printing and microfluidic systems.
With this advanced synthetic biomaterials, we would like to understand how the biomaterials-cell interactions can be regulated in order to enhance the cells osteoconductivity, osteoinductivity while also endowing anti-tumoral or anti-bacterial functionalities.
For more information, please visit Dr. Maleki´s website
Publications generated during 1/2023-12/2025 with CMMC affiliation
2024 (up to June)
- Abie N, Unlu C, Pinho AR, Gomes MC, Remmler T, Herb M, Grumme D, Tabesh E, Shahbazi MA, Mathur S, Mano JF, and Maleki H (2024). Designing of a Multifunctional 3D-Printed Biomimetic Theragenerative Aerogel Scaffold via Mussel-Inspired Chemistry: Bioactive Glass Nanofiber-Incorporated Self-Assembled Silk Fibroin with Antibacterial, Antiosteosarcoma, and Osteoinductive Properties. ACS Appl Mater Interfaces. doi:10.1021/acsami.4c00065.
- Tan V, Berg F, and Maleki H (2024). Diatom-inspired silicification process for development of green flexible silica composite aerogels. Sci Rep14, 6973. doi:10.1038/s41598-024-57257-x.
- Vaseghi A, Parchin RA, Chamanie KR, Herb M, Maleki H, and Sadeghizadeh M (2024). Encapsulation of propolis extracted with methylal in the chitosan nanoparticles and its antibacterial and cell cytotoxicity studies. BMC Complement Med Ther24, 165. doi:10.1186/s12906-024-04472-8.
- Zorron M, Cabrera AL, Sharma R, Radhakrishnan J, Abbaszadeh S, Shahbazi MA, Tafreshi OA, Karamikamkar S, and Maleki H (2024). Emerging 2D Nanomaterials-Integrated Hydrogels: Advancements in Designing Theragenerative Materials for Bone Regeneration and Disease Therapy. Adv Sci (Weinh), e2403204. doi:10.1002/advs.202403204.
2023
- Al-Jawuschi N, Chen S, Abie N, Fischer T, Fare S, and Maleki H (2023). Self-Assembly-Driven Bi(2)S(3) Nanobelts Integrated a Silk-Fibroin-Based 3D-Printed Aerogel-Based Scaffold with a Dual-Network Structure for Photothermal Bone Cancer Therapy. Langmuir 39, 4326-4337. doi:10.1021/acs.langmuir.2c03334.
- Karamikamkar S, Yalcintas EP, Haghniaz R, de Barros NR, Mecwan M, Nasiri R, Davoodi E, Nasrollahi F, Erdem A, Kang H, Lee J, Zhu Y, Ahadian S, Jucaud V, Maleki H, Dokmeci MR, Kim HJ, and Khademhosseini A (2023). Aerogel-Based Biomaterials for Biomedical Applications: From Fabrication Methods to Disease-Targeting Applications. Adv Sci (Weinh) 10, e2204681. doi:10.1002/advs.202204681.
- Paolieri M, Chen ZH, Kadumudi FB, Alehosseini M, Zorrón M, Dolatshahi-Pirouz A, and Maleki H (2023). Biomimetic Flexible Electronic Materials from Silk Fibroin-MXene Composites Developed Mussel-Inspired Chemistry as Wearable Pressure Sensors. Acs Applied Nano Materials 6, 5211-5223. doi:10.1021/acsanm.2c05140.
- Pektas HK, Demidov Y, Ahvan A, Abie N, Georgieva VS, Chen S, Fare S, Brachvogel B, Mathur S, and Maleki H (2023). MXene-Integrated Silk Fibroin-Based Self-Assembly-Driven 3D-Printed Theragenerative Scaffolds for Remotely Photothermal Anti-Osteosarcoma Ablation and Bone Regeneration. ACS Mater Au 3, 711-726. doi:10.1021/acsmaterialsau.3c00040.