Brachvogel, Bent - assoc. RG 50
Mitochondrial dysfunction in skeletal diseases
Prof. Dr. Bent Brachvogel
Department of Pediatrics and Adolescent Medicine
CMMC - PI - assoc. RG 50
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Department of Pediatrics and Adolescent Medicine
Kerpener Str. 62
50937 Cologne
Introduction
The content for this project has been requested and will be made available soon.
Affiliations
Lab Website
For more information, please check the research page of Prof Brachvogel.
Publications generated during 1/2023-12/2025 with CMMC affiliation
2025
- Weiss K, Agarkova Y, Zwosta A, Hoevel S, Himmelreich AK, Shumanska M, Etich J, Poschmann G, Brachvogel B, Bogeski I, Mielenz D, Riemer J. A fluorescent sensor for real-time monitoring of DPP8/9 reveals crucial roles in immunity and cancer. Life Sci Alliance. 2025 May 12;8(8):e202403076. doi: 10.26508/lsa.202403076. PMID: 40355159; PMCID: PMC12069513.
- Bubb K, Etich J, Probst K, Parashar T, Schuetter M, Dethloff F, Reincke S, Nolte JL, Krüger M, Schlötzer-Schrehard U, Nüchel J, Demetriades C, Giavalisco P, Riemer J, Brachvogel B. Metabolic rewiring caused by mitochondrial dysfunction promotes mTORC1-dependent skeletal aging. Sci Adv. 2025 Apr 18;11(16):eads1842. doi: 10.1126/sciadv.ads1842. Epub 2025 Apr 18. PMID: 40249823; PMCID: PMC12007575.
2024
- Boix J, Knuever J, Niehoff N, Sen A, Pla-Martin D, Baris OR, Etich J, Brachvogel B, Kaul H, Isbrandt D, Soroka E, Bazzi H, Wenger RH, Giavalisco P, Wiesner RJ. Constitutive HIF-1α Expression in the Epidermis Fuels Proliferation and Is Essential for Effective Barrier Formation. J Invest Dermatol. 2024 Nov 22:S0022-202X(24)02951-8. doi: 10.1016/j.jid.2024.09.022. Epub ahead of print. PMID: 39580109.
- Bopp L, Martinez ML, Schumacher C, Seitz R, Arana MH, Klapproth H, Lukas D, Oh JH, Neumayer D, Lackmann JW, Mueller S, von Stebut E, Brachvogel B, Brodesser S, Klein Geltink RI, Fabri M. Glutamine promotes human CD8+ T cells and counteracts imiquimod-induced T cell hyporesponsiveness. iScience. 2024 Apr 18;27(5):109767. doi: 10.1016/j.isci.2024.109767. PMID: 38736545; PMCID: PMC11088342.
- Reiter L, Niehoff N, Weiland D, Helbig D, Eming SA, Krieg T, Etich J, Brachvogel B, Wiesner RJ, Knuever J. Mitochondrial DNA mutations attenuate Bleomycin-induced dermal fibrosis by inhibiting differentiation into myofibroblasts. Matrix Biol. 2024 Sep;132:72-86. doi: 10.1016/j.matbio.2024.07.002. Epub 2024 Jul 14. PMID: 39009171.