Center for Molecular Medicine Cologne

Prof. Dr. med. Esther von Stebut-Borschitz - Curriculum Vitae

Education and professional career

2017: Director, Full Professor (W3), Dept. of Dermatology, University of Cologne
2013: Programme Director Mainz Graduate School for Translational Biomedicine (TransMed)
2009: Full Professor (W2) for Infectious Disease Dermatology, Dept. of Dermatology, University Medical Center Mainz, Germany
2007:
Board certification “Dermatopathology”
2004: Habilitation for Dermatology, University Mainz, Germany
2002: Senior physician at Department of Dermatology, University of Mainz, Germany
2002: Board certification “Dermatology / Venerology” and “Allergy”
1999: Group leader, Dept. of Dermatology, University of Mainz, Germany
1998-1999: Graduate Courses “Molecular and Cellular Mechanism of Immunity”/,,Cell Biology of Imnunity and Inflammation”, FAES, NIH, Bethesda, MD, USA
1997-1999: Postdoc at Dermatology Branch (M.C. Udey), National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
1995-1997: Intership/Resident at Dept. of Dermatology, Charite Berlin, Germany
1993-1994: Final year Medical School Internal Medicine (3 months)  & Surgery, University of Bern, Switzerland, Dept. of Dermatology, University of Lübeck, Germany
1990-1996: MD thesis, Dept. of Dermatology (U. Amon), University of Lübeck, Germany
1987-1994: Medical School, Medical University of Lübeck, Germany

Awards, distinctions and professional activities

since 2008: Head of Core Facility Histopathology
since 2002: Member of several SFBs and GK funded by the DFG
since 2001: Reviewer of Journals ( J. Exp. Med., Blood, J. Immunol., Ent. J. Immunol., J. Invest. Dermatol., etc.)
2015: Schaudinn – Hoffman Plakette of the German Dermatological Association
2009: Award of the German Associaton for Tropical Medicine
2007: Research Award of the Berlin Foundation for Dermatology
2006: Boehringer Ingelheim Award, School of Medicine,  University Mainz
2004: Egon Macher-Award of the German Society for Dermatological Research
2003:
Dagmar Eißner – Award for Junior Researchers, University Mainz
2001: Oscar – Gans Award of the German Dermatological Associaton

Selected publications

von Stebut E, and Tenzer S: Cutaneous leishmaniasis: Distinct functions of dendritic cells and macrophages in the interaction of the host immune system with Leishmania major. Int J Med Microbiol. 2017, S1438-4221: 30470-8.

Girard-Madoux MJ, Kautz-Neu K, Lorenz B, Ober-Blöbaum JL, von Stebut E*, and Clausen BE*, * joint senior-authors: IL-10 signaling in dendritic cells attenuates anti-Leishmania major immunity without affecting protective memory responses. J Invest Dermatol. 2015, 135: 2890-4.

Karbach S, Croxford AL, Oelze M, Schüler R, Minwegen D, Wegner J, Koukes L, Yogev N, Nikolaev A, Reißig S, Ullmann A, Knorr M, Waldner M, Neurath MF, Li H, Wu Z, Brochhausen C, Scheller J, Rose-John S, Piotrowski C, Bechmann I, Radsak M, Wild P, Daiber A, von Stebut E*, Wenzel P*, Waisman A*, and Münzel T*, * joint senior-authors: Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease. Arterioscler Thromb Vasc Biol. 2014, 34: 2658-68.

Kautz-Neu K, Noordegraaf M, Dinges S, Bennett CL, John D, Clausen BE*, and  von Stebut E*, * joint senior-authors: Langerhans cells are negative regulators of the anti-Leishmania response. J Exp Med. 2011, 208: 885-91.

Lopez Kostka S, Dinges S, Griewank K, Iwakura Y, Udey MC, and von Stebut E: IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice. J Immunol. 2009, 182: 3039-46.

Woelbing F, Kostka SL, Moelle K, Belkaid Y, Sunderkoetter C, Verbeek S, Waisman A, Nigg AP, Knop J, Udey MC, and von Stebut E: Uptake of Leishmania major by dendritic cells is mediated by Fcgamma receptors and facilitates acquisition of protective immunity. J Exp Med. 2006, 203: 177-88.

Maurer M, Lopez Kostka S, Siebenhaar F, Moelle K, Metz M, Knop J, and von Stebut E: Skin mast cells control T cell-dependent host defense in Leishmania major infections. FASEB J. 2006, 20: 2460-7.

von Stebut E, Ehrchen JM, Belkaid Y, Kostka SL, Molle K, Knop J, Sunderkotter C, and Udey MC: Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice. J Exp Med. 2003, 198: 191-9.

von Stebut E, Metz M, Milon G, Knop J, and Maurer M: Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1alpha /beta released from neutrophils recruited by mast cell-derived TNFalpha. Blood. 2003, 101: 210-5.

von Stebut E, Belkaid Y, Jakob T, Sacks DL, and Udey MC: Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity. J Exp Med. 1998, 188: 457-61.

* contributed equally