Center for Molecular Medicine Cologne

Markus Chmielewski / Andreas Hombach - assoc. RG 29

Metabolic addiction and reprogramming of an anti-tumor T cell response

Summary

In progress - further information will follow soon.

  • Oberbeck S, Schrader A, Warner K, Jungherz D, Crispatzu G, von Jan J, Chmielewski M, Ianevski A, Diebner HH, Mayer P, Kondo Ados A, Wahnschaffe L, Braun T, Muller TA, Wagle P, Bouska A, Neumann T, Putzer S, Varghese L, Pflug N, Thelen M, Makalowski J, Riet N, Gox HJM, Rappl G, Altmuller J, Kotrova M, Persigehl T, Hopfinger G, Hansmann ML, Schlosser H, Stilgenbauer S, Durig J, Mougiakakos D, von Bergwelt-Baildon M, Roeder I, Hartmann S, Hallek M, Moriggl RH, Bruggemann M, Aittokallio T, Iqbal J, Newrzela S, Abken H, and Herling M (2020). Non-canonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling. Blood 10.1182/blood.2019003348.
     
  • Hombach AA, Geumann U, Gunther C, Hermann FG, and Abken H (2020). IL7-IL12 Engineered Mesenchymal Stem Cells (MSCs) Improve A CAR T Cell Attack Against Colorectal Cancer Cells. Cells 9.
     
  • Patasic L, Seifried J, Bezler V, Kaljanac M, Schneider IC, Schmitz H, Tondera C, Hartmann J, Hombach A, Buchholz CJ, Abken H, Konig R, and Cichutek K (2020). Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4(+) T cells to reduce the latent HIV(+) cell reservoir. Medical microbiology and immunology 209, 681-91.
Dr. Markus Chmielewski CMMC Cologne
Dr. Markus Chmielewski

Laboratory for Tumor Genetics and Cellular Immunotherapy

assoc. CMMC Research Group

+49 221 478 89614

+49 221 478 7789

Laboratory for Tumor Genetics and Cellular Immunotherapy

Robert-Koch-Straße 21

50931 Cologne

CMMC Profile Page

Dr. med. Andreas Hombach CMMC Cologne
Dr. med. Andreas Hombach

Laboratory for Tumor Genetics and Cellular Immunotherapy

assoc. CMMC Research Group

+49 221 478 89639

Laboratory for Tumor Genetics and Cellular Immunotherapy

Robert-Koch-Straße 21

50931 Cologne

CMMC Profile Page

Group Members

Post Docs:

  • Tobias Riet

Technicians:

  • Danuta Chrobok
  • Petra Hofmann
  • Birgit Hops