Center for Molecular Medicine Cologne

32nd Ernst Klenk Symposium in Molecular Medicine

Precision oncology: Translating basic discoveries into patient survival

It gives us great pleasure to announce that this year´s  Klenk Symposium 2016 organized by the Center for Molecular Medicine Cologne (CMMC) on "Precision oncology: Translating basic discoveries into patient survival" was exceptionally outstanding.

Over 480 participants from over 24 countries took part in the Klenk Symposium 2016. We received excellent feedback from the participants regarding on our guest speakers' contribution and would like to forward one comment to you that reflects the overall atmosphere of the meeting:

"This year´s Klenk Symposium 2016 was exceptionally outstanding. The talks of the guest speakers were top high quality presenting interesting insights into the various aspects of precision oncology. The lively discussions after the talks during the poster presentation, as well as the scientific exchange throughout the meeting have been remarkably fruitful and still going on in all the different institutions of the participants".

We are honored that Charles Swanton - The Francis Crick Institute, London (UK) was substantially involved in the scientific coordination of the program jointly with Christian Reinhardt and Roman Thomas. Through his outstanding engagement we were able to present an excellent cutting-edge program with leading international experts who shared and discussed the latest advances in the fields of precision oncology.

Charles Swanton - The Francis Crick Institute, London (UK)
Scientific Coordinator and honorary key note speaker of the traditional
Ernst Klenk Lecture on Friday, Dec. 09, 2016.

Many thanks to all guest speakers

Session I:
Discovering basic principles of actionable genomic aberrations in cancer/tumor evolution/acquired resistance
Mathew Garnett - Cambridge, US - Stefan Pfister - Heidelberg, DE - Matthew L Meyerson - Boston, US - William R Sellers - Cambridge, US - Jeffrey A Sosman - Chicago, US - Louis M Staudt - Bethesda, US

Session II:
Using mouse models as preclinical avatars for the development of precision cancer medicine
Anton Berns - Amsterdam, NL - Lukas E Dow - New York, US - Pier P Pandolfi - Boston, US  - Julien Sage - Stanford, US - Dieter Saur - Munich, DE - Kwok K Wong - Boston, US

Session III:
Novel approaches for targeted intervention in solid tumors, lymphomas and leukemias
Enriqueta Felip - Barcelona, ES - John G Gribben - London, UK - Richard Marais - Manchester, UK - Matthew L Meyerson - Boston, US - Tony SK Mok - Hong Kong, HK - Clemens A Schmitt - Berlin, DE

Session IV:
Immune checkpoint blockade as a novel therapeutic approach
Gordon J Freeman - Boston, US - Michael Hölzel - Bonn, DE - William Pao - Basel, CH - Dirk Schadendorf - Essen, DE - Thomas Tüting - Magdeburg, DE - E John Wherry - Philadelphia, US


CMMC´Klenk Symposium Poster Award

During the poster presentation over 50 posters were presented (Program-Poster Abstract Book_Klenk 2016). The poster track provided an excellent forum to present original research results and promoted scientific interaction. The Poster Evaluation Committee awarded the poster prize to the first author of following poster presentations:

A 03 - MEK inhibitors block growth of lung tumors with mutations in Ataxia Telangiectasia Mutated
F. Fece de la Cruz1,2,3 / M. Smida3,4 / S. Nijman1,2,3
1 Ludwig Institute for Cancer Research, Univ. of Oxford, United Kingdom

C 07 - Attenuated Listeria monocytogenes as a promising vaccine candidate in the settings of hepatocellular carcinoma
L. Hoenicke1 - et al. - T. Yevsa1
1 Dept. of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Germany

C 18 - The RTK RET promotes AML through protection of FLT3-ITD from autophagy-mediated degradation
S. Rudat1 - et al. - C. Scholl1
Dept. of Translational Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), DE

The local Klenk Symposium Organization Committee very much enjoyed hosting such an outstanding conference and interacting with the guest speakers and the participants.

We hope that all guest speakers and pariticpants enjoyed your stay in Cologne and that you will have found the Klenk Conference 2016 a memorable occasion.

With best regards

Cologne Scientific Organization Klenk Symposium Committee 2016

Christian Reinhardt - Roman Thomas (Chairs)
Reinhard Büttner - Michal-Ruth Schweiger - Michael Hallek - Wilhelm Stoffel - Debora Grosskopf-Kroiher (Organization) - Thomas Benzing


Center for Molecular Medicine Cologne (CMMC) - University of Cologne
in association with

Center for Integrated OncologyKFO 286CRC 1218CRC 829CRC 670Dept. of Translational Genomicse:Med Systems MedicineLungCancerGroupColognesybacolITN CodeAgeCECAD CologneCologne Center for GenomicsDept. for PathologyDept. I for Internal MedicineClinical Trials Centre Cologne (ZKS Köln)University Hospital CologneORPHEUSBioRiver - Life Science im Rheinland e.V.

The CMMC organizer thanks the Cologne Convention Bureau for their excellent support.
Further information:

Certified with 16 CME Credits

by the Nordrheinische Akademie für ärztliche Fort- und Weiterbildung, Düsseldorf (Germany).

Poster Klenk 2016

Program Klenk 2016

Program and Poster Abstract Book

for download: Program-Abstract Book

Poster Presentation - Klenk Symposium 2016

We are pleased to welcome you to the poster session with 55 poster contributions for the following topics:

  • Poster A01 - A20 - related to Session A
  • Poster B01 - B10 - related to Session B
  • Poster C01 - C25 - related to Session C

Poster Award - Klenk Symposium 2016
This prize will be awarded to the three most outstanding poster contributions. The awardees are invited to give a short presentation (10 min.) during the last session on Saturday, Dec. 10, 2016.

For further information: Poster Session

Sponsors Klenk 2016