Center for Molecular Medicine Cologne

Welcome to the CMMC Annual Retreat 2019

Dear CMMC Members
Dear interested members of the Medical and Science Faculties

It is a great pleasure for us to welcome you and your group members as well as interested members of the Medical and Science Faculties to the CMMC Annual Retreat taking place at Tagungsstätte „Park-Hotel Nuembrecht“. The retreat starts on Wednesday - February 06, 2019 at 11 a.m. and ends on Thursday -  February 07, 2019 presumably at 2.00 p.m.

We are looking forward to a highly interactive meeting.

With best regards

Thomas Benzing
Chair of the CMMC and the EC Members

Program: CMMC Report - Short Talks - CMMC Lectures - Poster Session - Discussions - Networking

Over 58 research groups, six core facilities, the IPMM program complemented by additional research related activities are supported and integrated in the CMMC.

Based on a rotation system, every year a limited number of CMMC project groups are invited to present their progress report. To further facilitate networking and exchange within the CMMC, all CMMC project leaders of the different CMMC funding programs and heads of the core facilities are invited to present a poster during the CMMC poster sessions. The poster sessions will take place during the coffee and lunch breaks.

Program

CMMC Lectures

We are delighted to announce the following scientists, who accepted our invitation to participate in the Annual Retreat as keynote speakersof the CMMC Lectures

Program - Annual Retreat 2019

9:45 - 10.50 a.m.

Meeting of the CMMC Executive Board (for members of the EC Board only)

Seminar Room (opposite of the Lecture Hall)

 

Scientific Program - CMMC Annual Retreat 2019

Lecture Hall at the venue

11.00 - 11.30 a.m.

Welcome address - CMMC progress report (General Assembly)
Thomas Benzing - Chair of the Center for Molecular Medicine Cologne

Research Area A - Mechanisms of tumor development: intrinsic and extrinsic control of cell proliferation and tissue invasion

Chair: Margarethe Odenthal - Institute for Pathology

11.30 - 11.50 a.m.

C 10 - Metabolic regulation of skin barrier function in health and type II diabetes
Carien M Niessen - Department of Dermatology and CECAD

11.50 - 12.10 p.m.

A 8 - Cell death in the regulation of inflammation
Manolis Pasparakis - Institute for Genetics and CECAD

12.10 - 12.30 p.m

A 11 - Targeting oncogene-dependent lung cancer
Martin Sos - Institute for Pathology and Department of Translational Genomics

12.30 - 12.50 p.m.

CAP 9 - Strategies to improve treatment efficacy of immune check point targeted therapy
Sven Borchmann - Roland Ullrich - Department I of Internal Medicine

12.50 - 2.00 p.m.

Lunch Break and Poster Presentation

2.00 - 2.30 p.m.

Towards new challenges - official farewell
Hinirch Abken - Jay Gopalakrishnan - Argyris Papantonis -
Alvaro Rada-Iglesias
Chair: Thomas Benzing
 

CMMC Junior Lectures

Chair: Guenter Schwarz

2.30 - 3.00 p.m.

Consequences of epigenome structural alterations and its relationship with genome instability for age-related predisposition to disease development
Robert Hänsel-Hertsch - Cancer Research UK Cambridge Institute, Cambridge - GB

3.00 - 3.30 p.m.

Crosstalk of epigenetic regulators with(in) their chromatin environment
Simon Pöpsel
- Institutefor Quantitative Biosciences, University of California, Berkeley - US

3.30 - 3.50 p.m.

Coffee Break - with Poster Presentation

3.50 - 4.30 p.m.

CMMC Senior Lecture

Cell death in disease: inflammation beyond TNF
Henning Walczak - UCL Cancer Institute - London, GB
Laudatio: Thomas Benzing

4.30 - 4.50 p.m.

Coffee Break - with Poster Presentation

Chair: Michal Ruth Schweiger - Laboratory for Epigenomics and Tumorgenetics

4.50 - 5.10 p.m.

A 12 - The role of RNA splicing in the maintenance of transcription and genome integrity
Steffen Erkelenz - Mirka Uhlirova - Institute for Genetics and CECAD

5.10 - 5.30 p.m.

C 4 - Multi-omics systems genetics
Andreas Beyer1 - Argyris Papantonis2
CECAD Cologne1 - Institute for Human Genetics, University Göttingen and Center for Molecular Medicine Cologne 2

5.30 - 5.50 p.m.

A 7 - Stem cell function in skin cancer development
Catherin Niemann - Institute for Biochemistry and CMMC

5.50 - 6.00 p.m.

Coffee Break - with Poster Presentation

6.00 - 6.40 p.m.

CMMC Senior Lecture

Role of basement membrane laminins in control of vascular function
Lydia Sorokin - Institute for Physiological Chemistry and Pathobiochemistry, University of Münster - Münster, DE
Laudatio: Mats Paulsson

 
7. 30 p.m.

Reception followed by the CMMC Dinner at the venue

 

Research Area B: Principles of immunity, inflammation and infection

Chair: Guenter Schwarz - Institute for Biochemistry

9.00 - 9.20 a.m.

CAP 8 - Corticosteroids potently abrogate p38 MAPK dependent necrotic cell death induced by Mycobacterium tuberculosis - implications for host-derived therapies
Jessica Gräb - Jan Rybniker - Department I of Internal Medicine

9.20 - 9.40 a.m.

assoc. RG - Why any more research in Zika virus infection?
Olaf Utermöhlen - Institute for Med. Microbiology, Immunology and Hygiene

9.40 - 10.00 a.m.

B 4 - Control of host cell death by bacterial invaders
Hamid Kashkar - Institute for Med. Microbiology, Immunology and Hygiene and CECAD

10.00 - 10.20 a.m.

CAP 11 - The contribution of macrophages to inflammatory corneal lymphangiogenesis
Deniz Hos - Department of Ophthalmology

10.20 - 10.40 a.m. 

Coffee Break - with Poster Presentation

Research Area C: Molecular mechanisms and metabolic control of tissue degeneration and regeneration

Chair: Aleksandra Trifunovic - Institute for Mitochondrial Diseases and Ageing and CECAD

10.40 - 11.00 a.m. 

C 2 - Intravital imaging of podocyte signaling reveals that podocytes in a dish are not happy
Matthias Hackl - Thomas Benzing - Department II of Internal Medicine

11.00 - 11.20 a.m.

C 3 - Metabolic regulation of brain tissue repair by perivascular astrocytes
Matteo Bergami - CECAD

11.20 - 11.40 a.m.

assoc. JRG - Translational research for neuromuscular disorders: from genetic mutations to personalized medicine.
Sebahattin Cirak - Department of Pediatrics and Adolescent Medicine

11.40 - 12.20 p.m.

Lunch Break - with Poster Presentation

Chair: Brunhilde Wirth - Institute for Human Genetics

12.20 - 12.40 p.m.

C 5 / CAP 1 - Anaerobic glycolysis maintains the glomerular filtration barrier independent of mitochondrial metabolism and dynamics
Paul Brinkkötter - Department II of Internal Medicine
 

12.40 - 1.00 p.m.

C 8 - Development-specific phenotypes of HCN channelopathies in mice
Dirk Isbrandt1 - Maria A Rüger2 - Michael Schroeter2 - Igor Jakovcevski1 - Institute for Molecular and Behavioral Neuroscience1 andDepartment of Neurology2

1.00 - 1.20 p.m.

C 15 - CLPP protease: friend or foe
Aleksandra Trifunovic - Institute for Mitochondrial Diseases and Ageing and CECAD

1.20 - 1.40 p.m.

CAP 14 - Role of mitofusin 2 in health and disease
Mafalda Escobar-Henriques - Institute for Genetics and CECAD

1.40 - 2.00 p.m.

Final discussion and leave-taking

Thomas Benzing - Chair of the CMMC

Program - CMMC Annual Retreat 2019

Online registration closed

Online registration closed - please contact the CMMC Office if you have any questions

zmmk-office[at]uni-koeln.de


Venue

Tagungsstätte
Park-Hotel Nuembrecht
Parkstr. 3 - 51588 Nuembrecht
http://www.nuembrecht.com/en/

Bus Shuttle

The conference site - located 50 km east of Cologne in the Oberberg area - is difficult to reach by public transportation.

Time table of the bus shuttle:
Feb. 06, 2019: 9:00 a.m. - departure from the CMMC-Research Building, Robert-Koch-Str. 21
Feb. 07, 2018: 2:00 p.m. - departure from Park-Hotel Nuembrecht to Cologne

Directions by car

Please visit following link: http://www.nuembrecht.com/en/directions

Please note: destination address for navigation system: Weiherstrasse, 51588 Nuembrecht