Summary of articles published by CMMC members in 2024

Original Articles, Reviews and Publications in Clinical and Translational Research with CMMC affiliation listed in alphabetical order by first author published in 2024 (until June).

  • Abie N, Unlu C, Pinho AR, Gomes MC, Remmler T, Herb M, Grumme D, Tabesh E, Shahbazi MA, Mathur S, Mano JF, and Maleki H (2024). Designing of a Multifunctional 3D-Printed Biomimetic Theragenerative Aerogel Scaffold via Mussel-Inspired Chemistry: Bioactive Glass Nanofiber-Incorporated Self-Assembled Silk Fibroin with Antibacterial, Antiosteosarcoma, and Osteoinductive Properties. ACS Appl Mater Interfaces. doi:10.1021/acsami.4c00065.
     
  • Albert MC, Uranga-Murillo I, Arias M, De Miguel D, Pena N, Montinaro A, Varanda AB, Theobald SJ, Areso I, Saggau J, Koch M, Liccardi G, Peltzer N, Rybniker J, Hurtado-Guerrero R, Merino P, Monzon M, Badiola JJ, Reindl-Schwaighofer R, Sanz-Pamplona R, Cebollada-Solanas A, Megyesfalvi Z, Dome B, Secrier M, Hartmann B, Bergmann M, Pardo J, and Walczak H (2024). Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality. Cell Death Differ. doi:10.1038/s41418-024-01278-6.
     
  • Alidousty C, Becker A, Binot E, Hillmer AM, Merkelbach-Bruse S, Budde B, Bassmann I, Rappl G, Wolf J, Eich ML, Noh KW, Buettner R, and Schultheis AM (2024). Frequency and functional characterization of fusion genes in squamous cell carcinoma of the lung. Gene895, 148018. doi:10.1016/j.gene.2023.148018.
     
  • Arjune S, Spath MR, Oehm S, Todorova P, Schunk SJ, Lettenmeier K, Chon SH, Bartram MP, Antczak P, Grundmann F, Fliser D, and Muller RU (2024). DKK3 as a potential novel biomarker in patients with autosomal polycystic kidney disease. Clin Kidney J17, sfad262. doi:10.1093/ckj/sfad262.
     
  • Arvanitaki ES, Goulielmaki E, Gkirtzimanaki K, Niotis G, Tsakani E, Nenedaki E, Rouska I, Kefalogianni M, Xydias D, Kalafatakis I, Psilodimitrakopoulos S, Karagogeos D, Schumacher B, Stratakis E, and Garinis GA (2024). Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage. Proc Natl Acad Sci U S A121, e2317402121. doi:10.1073/pnas.2317402121.
     
  • Benard EL, Kucukaylak I, Hatzold J, Berendes KUW, Carney TJ, Beleggia F, and Hammerschmidt M (2024). wnt10a is required for zebrafish median fin fold maintenance and adult unpaired fin metamorphosis. Dev Dyn253, 566-592. doi:10.1002/dvdy.672.
     
  • Bopp L, Martinez ML, Schumacher C, Seitz R, Arana MH, Klapproth H, Lukas D, Oh JH, Neumayer D, Lackmann JW, Mueller S, von Stebut E, Brachvogel B, Brodesser S, Klein Geltink RI, and Fabri M (2024). Glutamine promotes human CD8(+) T cells and counteracts imiquimod-induced T cell hyporesponsiveness. iScience27, 109767. doi:10.1016/j.isci.2024.109767.
     
  • Buchholz S, and Zempel H (2024). Suppression of mature TAU isoforms prevents Alzheimer's disease-like amyloid-beta oligomer-induced spine loss in rodent neurons. Neural Regen Res19, 1655-1657. doi:10.4103/1673-5374.389644.
     
  • Camblor-Perujo S, Ozer Yildiz E, Kupper H, Overhoff M, Rastogi S, Bazzi H, and Kononenko NL (2024). The AP-2 complex interacts with gamma-TuRC and regulates the proliferative capacity of neural progenitors. Life Sci Alliance7. doi:10.26508/lsa.202302029.
     
  • Carrera P, Odenthal J, Risse KS, Jung Y, Kuerschner L, and Bulow MH (2024). The CD36 scavenger receptor Bez regulates lipid redistribution from fat body to ovaries in Drosophila. Development151. doi:10.1242/dev.202551.
     
  • Charmpilas N, Sotiriou A, Axarlis K, Tavernarakis N, and Hoppe T (2024). Reproductive regulation of the mitochondrial stress response in Caenorhabditis elegans. Cell Rep43, 114336. doi:10.1016/j.celrep.2024.114336.
     
  • Chen C, Altafi M, Corbu MA, Trenk A, van den Munkhof H, Weineck K, Bender F, Carus-Cadavieco M, Bakhareva A, Korotkova T, and Ponomarenko A (2024). The dynamic state of a prefrontal-hypothalamic-midbrain circuit commands behavioral transitions. Nat Neurosci. doi:10.1038/s41593-024-01598-3.
     
  • Darguzyte M, Rama E, Rix A, Baier J, Hermann J, Rezvantalab S, Khedri M, Jankowski J, and Kiessling F (2024). Riboflavin-targeted polymers improve tolerance of paclitaxel while maintaining therapeutic efficacy. Nanomedicine58, 102751. doi:10.1016/j.nano.2024.102751.
     
  • De Solis AJ, Del Rio-Martin A, Radermacher J, Chen W, Steuernagel L, Bauder CA, Eggersmann FR, Morgan DA, Cremer AL, Sue M, Germer M, Kukat C, Vollmar S, Backes H, Rahmouni K, Kloppenburg P, and Bruning JC (2024). Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism. Nat Metab6, 473-493. doi:10.1038/s42255-024-00987-z.
     
  • Engelhardt PM, Veronese M, Eryigit AA, Das A, Kaczmarek AT, Rugarli EI, and Schmalz HG (2024). A pH-Sensitive Double Chromophore Fluorescent Dye for Live-Tracking of Lipophagy. Chemistry30, e202400808. doi:10.1002/chem.202400808.
     
  • Eren RO, Kaya GG, Schwarzer R, and Pasparakis M (2024). IKKepsilon and TBK1 prevent RIPK1 dependent and independent inflammation. Nat Commun15, 130. doi:10.1038/s41467-023-44372-y.
     
  • Fages V, Bourre F, Larrue R, Wenzel A, Gibier JB, Bonte F, Dhaenens CM, Kidd K, Kmoch S, Bleyer A, Glowacki F, and Grunewald O (2024). Description of a New Simple and Cost-Effective Molecular Testing That Could Simplify MUC1 Variant Detection. Kidney Int Rep9, 1451-1457. doi:10.1016/j.ekir.2024.01.058.
     
  • Gajarsky M, Stadlbauer P, Sponer J, Cucchiarini A, Dobrovolna M, Brazda V, Mergny JL, Trantirek L, and Lenarcic Zivkovic M (2024). DNA Quadruplex Structure with a Unique Cation Dependency. Angew Chem Int Ed Engl63, e202313226. doi:10.1002/anie.202313226.
     
  • Garcia-Marquez MA, Thelen M, Bauer E, Maas L, Wennhold K, Lehmann J, Keller D, Nikolic M, George J, Zander T, Schroder W, Muller P, Yazbeck AM, Bruns C, Thomas R, Gathof B, Quaas A, Peifer M, Hillmer AM, von Bergwelt-Baildon M, and Schlosser HA (2024). Germline homozygosity and allelic imbalance of HLA-I are common in esophagogastric adenocarcinoma and impair the repertoire of immunogenic peptides. J Immunother Cancer12. doi:10.1136/jitc-2023-007268.
     
  • Gorantla SP, Mueller TA, Albers-Leischner C, Rudelius M, von Bubnoff N, and Duyster J (2024). A newly identified 45-kDa JAK2 variant with an altered kinase domain structure represents a novel mode of JAK2 kinase inhibitor resistance. Mol Oncol18, 415-430. doi:10.1002/1878-0261.13566.
     
  • Gries R, Chhen J, van Gumpel E, Theobald SJ, Sonnenkalb L, Utpatel C, Metzen F, Koch M, Dallenga T, Djaout K, Baulard A, Dal Molin M, and Rybniker J (2024). Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system. Cell Chem Biol31, 699-711 e696. doi:10.1016/j.chembiol.2023.12.007.
     
  • Grzonka M, and Bazzi H (2024). Mouse SAS-6 is required for centriole formation in embryos and integrity in embryonic stem cells. Elife13. doi:10.7554/eLife.94694.
     
  • Hamdorf M, Imhof T, Bailey-Elkin B, Betz J, Theobald SJ, Simonis A, Di Cristanziano V, Gieselmann L, Dewald F, Lehmann C, Augustin M, Klein F, Alejandre Alcazar MA, Rongisch R, Fabri M, Rybniker J, Goebel H, Stetefeld J, Brachvogel B, Cursiefen C, Koch M, and Bock F (2024). The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm. J Mol Cell Biol15. doi:10.1093/jmcb/mjad062.
     
  • Henschke S, Nolte H, Magoley J, Kleele T, Brandt C, Hausen AC, Wunderlich CM, Bauder CA, Aschauer P, Manley S, Langer T, Wunderlich FT, and Bruning JC (2024). Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver. Science384, 438-446. doi:10.1126/science.adk1005.
     
  • Hou Y, Zhang W, Le VNH, Deng S, Hadrian K, Mestanoglu M, Musial G, Bock F, and Cursiefen C (2024). Efficacy and safety of combined UV-light corneal crosslinking and fine-needle diathermy to regress pathological murine corneal (lymph)angiogenesis in vivo. Acta Ophthalmol. doi:10.1111/aos.16696.
     
  • Howaldt A, Lenglez S, Velmans C, Schultheis AM, Clahsen T, Matthaei M, Kohlhase J, Vokuhl C, Buttner R, Netzer C, Demoulin JB, and Cursiefen C (2024). Corneal Infantile Myofibromatosis Caused by Novel Activating Imatinib-Responsive Variants in PDGFRB. Ophthalmol Sci4, 100444. doi:10.1016/j.xops.2023.100444.
     
  • Hurcombe JA, Barrington F, Marchetti M, Betin VMS, Bowen EE, Lay AC, Ni L, Dayalan L, Pope RJP, Brinkkoetter PT, Holzenberger M, Welsh GI, and Coward RJM (2024). Contrasting consequences of podocyte insulin-like growth factor 1 receptor inhibition. iScience27, 109749. doi:10.1016/j.isci.2024.109749.
     
  • Imai T, Lin J, Kaya GG, Ju E, Kondylis V, Kelepouras K, Liccardi G, Kim C, and Pasparakis M (2024). The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation. Immunity. doi:10.1016/j.immuni.2024.04.016.
     
  • Injarabian L, Willenborg S, Welcker D, Sanin DE, Pasparakis M, Kashkar H, and Eming SA (2024). FADD- and RIPK3-Mediated Cell Death Ensures Clearance of Ly6C(high) Wound Macrophages from Damaged Tissue. J Invest Dermatol144, 152-164 e157. doi:10.1016/j.jid.2023.06.203.
     
  • Iqbal S, Schneider TK, Truong TT, Ulrich-Muller R, Nguyen PH, Ilyas S, and Mathur S (2024). Carriers for hydrophobic drug molecules: lipid-coated hollow mesoporous silica particles, and the influence of shape and size on encapsulation efficiency. Nanoscale16, 11274-11289. doi:10.1039/d4nr01420k.
     
  • Jakwerth CA, Weckmann M, Illi S, Charles H, Zissler UM, Oelsner M, Guerth F, Omony J, Nemani SSP, Grychtol R, Dittrich AM, Skevaki C, Foth S, Weber S, Alejandre Alcazar MA, van Koningsbruggen-Rietschel S, Brock R, Blau S, Hansen G, Bahmer T, Rabe KF, Brinkmann F, Kopp MV, Chaker AM, Schaub B, von Mutius E, Schmidt-Weber CB, and Research ASGapotGCfL (2024). 17q21 Variants Disturb Mucosal Host Defense in Childhood Asthma. Am J Respir Crit Care Med209, 947-959. doi:10.1164/rccm.202305-0934OC.
     
  • James R, Faller KME, Groen EJN, Wirth B, and Gillingwater TH (2024). Altered mitochondrial function in fibroblast cell lines derived from disease carriers of spinal muscular atrophy. Commun Med (Lond)4, 86. doi:10.1038/s43856-024-00515-w.
     
  • Jaylet T, Coustillet T, Smith NM, Viviani B, Lindeman B, Vergauwen L, Myhre O, Yarar N, Gostner JM, Monfort-Lanzas P, Jornod F, Holbech H, Coumoul X, Sarigiannis DA, Antczak P, Bal-Price A, Fritsche E, Kuchovska E, Stratidakis AK, Barouki R, Kim MJ, Taboureau O, Wojewodzic MW, Knapen D, and Audouze K (2024). Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps. Front Toxicol6, 1285768. doi:10.3389/ftox.2024.1285768.
     
  • Jestrabek H, Kohlhas V, Hallek M, and Nguyen PH (2024). Impact of leukemia-associated macrophages on the progression and therapy response of chronic lymphocytic leukemia. Leuk Res143, 107531. doi:10.1016/j.leukres.2024.107531.
     
  • Joy JD, Malacrida B, Laforets F, Kotantaki P, Maniati E, Manchanda R, Annibaldi A, Hopkins S, Garrobo-Calleja I, Gautrot J, and Balkwill FR (2024). Human 3D ovarian cancer models reveal malignant cell intrinsic and extrinsic factors that influence CAR T cell activity. Cancer Res. doi:10.1158/0008-5472.CAN-23-3007.
     
  • Kasper JY, Laschke MW, Koch M, Alibardi L, Magin T, Niessen CM, and Del Campo A (2024). Actin-templated Structures: Nature's Way to Hierarchical Surface Patterns (Gecko's Setae as Case Study). Adv Sci (Weinh)11, e2303816. doi:10.1002/advs.202303816.
     
  • Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Kunkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruss A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, and Wagner DL (2024). Integration of zeta-deficient CARs into the CD3zeta gene conveys potent cytotoxicity in T and NK cells. Blood143, 2599-2611. doi:10.1182/blood.2023020973.
     
  • Kelepouras K, Saggau J, Varanda AB, Zrilic M, Kiefer C, Rakhsh-Khorshid H, Lisewski I, Uranga-Murillo I, Arias M, Pardo J, Tonnus W, Linkermann A, Annibaldi A, Walczak H, and Liccardi G (2024). The importance of murine phospho-MLKL-S345 in situ detection for necroptosis assessment in vivo. Cell Death Differ. doi:10.1038/s41418-024-01313-6.
     
  • Khatif H, and Bazzi H (2024). Generation and characterization of a Dkk4-Cre knock-in mouse line. Genesis62, e23532. doi:10.1002/dvg.23532.
     
  • Kim S, Shahab J, Vogelsang E, and Wodarz A (2024). Re-assessment of the subcellular localization of Bazooka/Par-3 in Drosophila: No evidence for localization to the nucleus and the neuromuscular junction. Biol Open. doi:10.1242/bio.060544.
     
  • Klein S, Tolkach Y, Reinhardt HC, Buettner R, Quaas A, and Helbig D (2024). Proteomic analysis of pleomorphic dermal sarcoma reveals a fibroblastic cell of origin and distinct immune evasion mechanisms. Sci Rep14, 12516. doi:10.1038/s41598-024-62927-x.
     
  • Knopf JD, Steigleder SS, Korn F, Kuhnle N, Badenes M, Tauber M, Theobald SJ, Rybniker J, Adrain C, and Lemberg MK (2024). RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling. Nat Commun15, 1528. doi:10.1038/s41467-024-45615-2.
     
  • Koerner L, Wachsmuth L, Kumari S, Schwarzer R, Wagner T, Jiao H, and Pasparakis M (2024). ZBP1 causes inflammation by inducing RIPK3-mediated necroptosis and RIPK1 kinase activity-independent apoptosis. Cell Death Differ. doi:10.1038/s41418-024-01321-6.
     
  • Kosnik MB, Antczak P, and Fantke P (2024). Data-Driven Characterization of Genetic Variability in Disease Pathways and Pesticide-Induced Nervous System Disease in the United States Population. Environ Health Perspect132, 57003. doi:10.1289/EHP14108.
     
  • Laudenberg N, Kinuthia UM, and Langmann T (2023). Microglia depletion/repopulation does not affect light-induced retinal degeneration in mice. Front Immunol14, 1345382. doi:10.3389/fimmu.2023.1345382.
     
  • Legare S, Heide F, Gabir H, Rafiei F, Meier M, Padilla-Meier GP, Koch M, and Stetefeld J (2024). Identifying the molecular basis of Laminin N-terminal domain Ca(2+) binding using a hybrid approach. Biophys J. doi:10.1016/j.bpj.2024.06.005.
     
  • Leon S, Simon V, Lee TH, Steuernagel L, Clark S, Biglari N, Leste-Lasserre T, Dupuy N, Cannich A, Bellocchio L, Zizzari P, Allard C, Gonzales D, Le Feuvre Y, Lhuillier E, Brochard A, Nicolas JC, Teillon J, Nikolski M, Marsicano G, Fioramonti X, Bruning JC, Cota D, and Quarta C (2024). Single cell tracing of Pomc neurons reveals recruitment of 'Ghost' subtypes with atypical identity in a mouse model of obesity. Nat Commun15, 3443. doi:10.1038/s41467-024-47877-2.
     
  • Li-Bao L, Diaz-Diaz C, Raiola M, Sierra R, Temino S, Moya FJ, Rodriguez-Perales S, Santos E, Giovinazzo G, Bleckwehl T, Rada-Iglesias A, Spitz F, and Torres M (2024). Regulation of Myc transcription by an enhancer cluster dedicated to pluripotency and early embryonic expression. Nat Commun15, 3931. doi:10.1038/s41467-024-48258-5.
     
  • Lukomski L, Pisula J, Wagner T, Sabov A, Grosse Hokamp N, Bozek K, Popp F, Kann M, Kurschat C, Becker JU, Bruns C, Thomas M, and Stippel D (2024). First experiences with machine learning predictions of accelerated declining eGFR slope of living kidney donors 3 years after donation. J Nephrol. doi:10.1007/s40620-024-01967-y.
     
  • Lyu SI, Johannsen J, Simon AG, Knipper K, Wuerdemann N, Sharma SJ, Thelen M, Hansen KK, Fretter C, Klasen C, Esser J, Suchan MC, Abing H, Zimmermann PH, Schultheis AM, Schloesser HA, Klussmann JP, Quaas A, and Eckel HNC (2024). Co-expression patterns of cancer associated fibroblast markers reveal distinct subgroups related to patient survival in oropharyngeal squamous cell carcinoma. Front Cell Dev Biol12, 1337361. doi:10.3389/fcell.2024.1337361.
     
  • Marner M, Kulhanek N, Eichberg J, Hardes K, Molin MD, Rybniker J, Kirchner M, Schaberle TF, and Gottlich R (2024). Design, synthesis and antimycobacterial activity of imidazo[1,5-a]quinolines and their zinc-complexes. RSC Med Chem15, 1746-1750. doi:10.1039/d4md00086b.
     
  • Maus I, Dreiner M, Zetzsche S, Metzen F, Ross BC, Mahlich D, Koch M, Niehoff A, and Wirth B (2024). Osteoclast-specific Plastin 3 knockout in mice fail to develop osteoporosis despite dramatic increased osteoclast resorption activity. JBMR Plus8, ziad009. doi:10.1093/jbmrpl/ziad009.
     
  • Meder L, Orschel CI, Otto CJ, Koker M, Bragelmann J, Ercanoglu MS, Dahling S, Compes A, Selenz C, Nill M, Dietlein F, Florin A, Eich ML, Borchmann S, Odenthal M, Blazquez R, Hilberg F, Klein F, Hallek M, Buttner R, Reinhardt HC, and Ullrich RT (2024). Blocking the angiopoietin-2-dependent integrin beta-1 signaling axis abrogates small cell lung cancer invasion and metastasis. JCI Insight9. doi:10.1172/jci.insight.166402.
     
  • Meyer DH, and Schumacher B (2024). Aging clocks based on accumulating stochastic variation. Nat Aging. doi:10.1038/s43587-024-00619-x.
     
  • Michelatti D, Beyes S, Bernardis C, Negri ML, Morelli L, Bediaga NG, Poli V, Fagnocchi L, Lago S, D'Annunzio S, Cona N, Gaspardo I, Bianchi A, Jovetic J, Gianesello M, Turdo A, D'Accardo C, Gaggianesi M, Dori M, Forcato M, Crispatzu G, Rada-Iglesias A, Sosa MS, Timmers HTM, Bicciato S, Todaro M, Tiberi L, and Zippo A (2024). Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory. Nat Commun15, 2198. doi:10.1038/s41467-024-46524-0.
     
  • Moliere A, Park JYC, Goyala A, Vayndorf EM, Zhang B, Hsiung KC, Jung Y, Kwon S, Statzer C, Meyer D, Nguyen R, Chadwick J, Thompson MA, Schumacher B, Lee SV, Essmann CL, MacArthur MR, Kaeberlein M, David D, Gems D, and Ewald CY (2024). Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age. Geroscience. doi:10.1007/s11357-024-01232-x.
     
  • Moschandrea C, Kondylis V, Evangelakos I, Herholz M, Schneider F, Schmidt C, Yang M, Ehret S, Heine M, Jaeckstein MY, Szczepanowska K, Schwarzer R, Baumann L, Bock T, Nikitopoulou E, Brodesser S, Kruger M, Frezza C, Heeren J, Trifunovic A, and Pasparakis M (2024). Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes. Nature625, 385-392. doi:10.1038/s41586-023-06857-0.
     
  • Naji H, Sancere L, Simon A, Buttner R, Eich ML, Lohneis P, and Bozek K (2024). HoLy-Net: Segmentation of histological images of diffuse large B-cell lymphoma. Comput Biol Med170, 107978. doi:10.1016/j.compbiomed.2024.107978.
     
  • Nisar H, Labonte FM, Roggan MD, Schmitz C, Chevalier F, Konda B, Diegeler S, Baumstark-Khan C, and Hellweg CE (2024). Hypoxia Modulates Radiosensitivity and Response to Different Radiation Qualities in A549 Non-Small Cell Lung Cancer (NSCLC) Cells. Int J Mol Sci25. doi:10.3390/ijms25021010.
     
  • Oda H, Manthiram K, Chavan PP, Rieser E, Veli O, Kaya O, Rauch C, Nakabo S, Kuehn HS, Swart M, Wang Y, Celik NI, Molitor A, Ziaee V, Movahedi N, Shahrooei M, Parvaneh N, Alipour-Olyei N, Carapito R, Xu Q, Preite S, Beck DB, Chae JJ, Nehrebecky M, Ombrello AK, Hoffmann P, Romeo T, Deuitch NT, Matthiasardottir B, Mullikin J, Komarow H, Stoddard J, Niemela J, Dobbs K, Sweeney CL, Anderton H, Lawlor KE, Yoshitomi H, Yang D, Boehm M, Davis J, Mudd P, Randazzo D, Tsai WL, Gadina M, Kaplan MJ, Toguchida J, Mayer CT, Rosenzweig SD, Notarangelo LD, Iwai K, Silke J, Schwartzberg PL, Boisson B, Casanova JL, Bahram S, Rao AP, Peltzer N, Walczak H, Lalaoui N, Aksentijevich I, and Kastner DL (2024). Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency. Nat Immunol. doi:10.1038/s41590-024-01817-w.
     
  • Palikyras S, Sofiadis K, Stavropoulou A, Danieli-Mackay A, Varamogianni-Mamatsi V, Horl D, Nasiscionyte S, Zhu Y, Papadionysiou I, Papadakis A, Josipovic N, Zirkel A, O'Connell A, Loughran G, Keane J, Michel A, Wagner W, Beyer A, Harz H, Leonhardt H, Lukinavicius G, Nikolaou C, and Papantonis A (2024). Rapid and synchronous chemical induction of replicative-like senescence via a small molecule inhibitor. Aging Cell, e14083. doi:10.1111/acel.14083.
     
  • Pass T, Ricke KM, Hofmann P, Chowdhury RS, Nie Y, Chinnery P, Endepols H, Neumaier B, Carvalho A, Rigoux L, Steculorum SM, Prudent J, Riemer T, Aswendt M, Liss B, Brachvogel B, and Wiesner RJ (2024). Preserved striatal innervation maintains motor function despite severe loss of nigral dopaminergic neurons. Brain. doi:10.1093/brain/awae089.
     
  • Peters VBM, Matheis F, Erdmann I, Nemade HN, Muders D, Toubartz M, Torun M, Mehrkens D, Geissen S, Nettersheim FS, Picard F, Guthoff H, Hof A, Arkenberg P, Arand B, Klinke A, Rudolph V, Hansen HP, Bachurski D, Adam M, Hoyer FF, Winkels H, Baldus S, and Mollenhauer M (2024). Myeloperoxidase induces monocyte migration and activation after acute myocardial infarction. Front Immunol15, 1360700. doi:10.3389/fimmu.2024.1360700.
     
  • Prinz LF, Riet T, Neureuther DF, Lennartz S, Chrobok D, Hubbe H, Uhl G, Riet N, Hofmann P, Hosel M, Simon AG, Tetenborg L, Segbers P, Shimono J, Godel P, Balke-Want H, Flumann R, Knittel G, Reinhardt HC, Scheid C, Buttner R, Chapuy B, Ullrich RT, Hallek M, and Chmielewski MM (2024). An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL. Cell Rep Med5, 101421. doi:10.1016/j.xcrm.2024.101421.
     
  • Proff A, Nazet U, Schroder A, and Jantsch J (2024). Mechanical Stress Induces Sodium Entry and Osmoprotective Responses in Murine Synovial Fibroblasts. Cells13. doi:10.3390/cells13060496.
     
  • Przyklenk M, Karmacharya S, Bonasera D, Pasanen-Zentz AL, Kmoch S, Paulsson M, Wagener R, Liccardi G, and Schiavinato A (2024). ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder. Sci Rep14, 9321. doi:10.1038/s41598-024-59901-y.
     
  • Radvanyi Z, Yoo EJ, Kandasamy P, Salas-Bastos A, Monnerat S, Refardt J, Christ-Crain M, Hayashi H, Kondo Y, Jantsch J, Rubio-Aliaga I, Sommer L, Wagner CA, Hediger MA, Kwon HM, Loffing J, and Pathare G (2024). Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation. J Biol Chem300, 105480. doi:10.1016/j.jbc.2023.105480.
     
  • Raote I, Rosendahl AH, Hakkinen HM, Vibe C, Kucukaylak I, Sawant M, Keufgens L, Frommelt P, Halwas K, Broadbent K, Cunquero M, Castro G, Villemeur M, Nuchel J, Bornikoel A, Dam B, Zirmire RK, Kiran R, Carolis C, Andilla J, Loza-Alvarez P, Ruprecht V, Jamora C, Campelo F, Kruger M, Hammerschmidt M, Eckes B, Neundorf I, Krieg T, and Malhotra V (2024). TANGO1 inhibitors reduce collagen secretion and limit tissue scarring. Nat Commun15, 3302. doi:10.1038/s41467-024-47004-1.
     
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