Center for Molecular Medicine Cologne

Prof. Dr. med. Dr. h.c. Thomas Krieg - Curriculum Vitae

Education and professional career

since 2015: Speaker, Leopoldina class III (medicine), National Academy of Science
2012: Dr. honoris causa, Lund University, Sweden
since 2011: Dean, Medical Faculty, University of Cologne
since 2009: Member, Founding Council University Medicine and University of Göttingen
2006 - 2015: Obmann and Senator Internal Medicine, National Academy of Science Leopoldina
since 2005: Honorary Fellow of the Royal College of Physicians, London
2003 - 2015: Chair, Collaborative Research Center Cologne, SFB 589 / 829
2002 - 2011: Chair, German Network for Systemic Scleroderma
2001 - 2011: Member, Advisory Board of Deutsche Krebshilfe
2001 - 2011: Prorector for Research, University of Cologne
1999: Dr. honoris causa, Semmelweis University, Budapest, Hungary
since 1998: Member, National Academy of Science Leopoldina
1995 - 2003: Director of the Center for Molecular Medicine Cologne
1991: Max-Planck-Research Award of the A.v. Humboldt Society
since 1991: Professor and Director, Department of Dermatology, University of Cologne
1986 - 1991: Associate Professor, Department of Dermatology, Munich University
1984 - 1985: Heisenberg fellow, National Institutes of Health, Bethesda, USA
1980 - 1984: Residency in Dermatology, Munich University
1979: Otto Hahn Medal of the Max Planck Society
1979: Postdoctoral training, Institute for Cell Genetics, Karolinska Institute, Stockholm, Sweden
1975 - 1979: Research assistant, MPI for Biochemistry, Martinsried
1975: MD thesis in Pharmacology, Berlin Free University

Selected publications

Ghatak S, Niland S, Schulz JN, Wang F, Eble JA, Leitges M, Mauch C, Krieg T, Zigrino P, Eckes B. Role of integrins α1β1 and α2β1 in wound and tumor angiogenesis in mice. Am J Pathol. 2016, 186, 3011-3027.

Fleger-Weckmann A, Üstün Y, Kloepper J, Paus R, Bloch W, Chen ZL, Wegner J, Sorokin L, Langbein L, Eckes B, Zigrino P, Krieg T, Nischt R. Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis. Matrix Biol. 2016, 56, 42-56.

Khanna D, Denton CP, Merkel PA, Krieg T, Le Brun FO, Marr A, Papadakis K, Pope J, Matucci-Cerinic M, Furst DE; DUAL-1 Investigators, DUAL-2 Investigators. Effect of Macitentan on the development of new ischemic digital ulcers in patients with systemic sclerosis: DUAL-1 and DUAL-2 randomized clinical trials. JAMA. 2016, 315, 1975-1988.

Schulz JN, Nüchel J, Niehoff A, Bloch W, Schönborn K, Hayashi S, Kamper M, Brinckmann J, Plomann M, Paulsson M, Krieg T, Zaucke F, Eckes B. COMP-assisted collagen secretion--a novel intracellular function required for fibrosis. J Cell Sci. 2016, 129, 706-716.

Radovanac K, Morgner J, Schulz JN, Blumbach K, Patterson C, Geiger T, Mann M, Krieg T, Eckes B, Fässler R, Wickström SA. Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response. EMBO J. 2013, 32, 1409-1424.

Agarwal P, Zwolanek D, Keene DR, Schulz JN, Blumbach K, Heinegård D, Zaucke F, Paulsson M, Krieg T, Koch M, Eckes B. Collagen XII and XIV, new partners of cartilage oligomeric matrix protein in the skin extracellular matrix suprastructure. J Biol Chem. 2012, 287, 22549-22559.

Blumbach K, Zweers MC, Brunner G, Peters AS, Schmitz M, Schulz JN, Schild A, Denton CP, Sakai T, Faessler R, Krieg T, Eckes B. Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGF-β1 levels and RhoA activity J Cell Sci. 2010, 123, 3872-3883.

Lucas T, Waisman A, Ranjan R, Roes J, Krieg T, Müller W, Roers A, Eming SA. Differential roles of macrophages in diverse phases of skin repair. J Immunol. 2010, 184, 3964-3977.

Gabrielli A, Avvedimento EV, Krieg T. Scleroderma. New Engl J Med. 2009, 360, 1989-2003.

Zweers MC, Davidson JM, Pozzi A, Hallinger R, Janz K, Quondamatteo F, Leutgeb B, Krieg T, Eckes B. Integrin α2β1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization. J Invest Dermatol. 2007, 127, 467-478.