Prof. Dr. med. Maria A Rüger - Curriculum Vitae

Education and professional career

since 2013: Consultant physician (‘Oberärztin’) at the Department of Neurology, University Hospital of Cologne (Director: Prof. G.R. Fink)
since 2013: Research group leader of the ‘Neural Stem Cell Laboratory’, associated with the Department of Neurology, University Hospital of Cologne
2013: ‘Habilitation’ and ‘Venia legendi’ for Neurology at the University Hospital of Cologne: “Imaging-guided development of stem cell-based therapies for stroke”
since 2011: Senior scientist at the Department of Neurology, Laboratory for Experimental Neuroimmunology
2011: Board certification for Neurology
2007 – 2011: Residency in clinical neurology at the Department of Neurology, University Hospital of Cologne (Director: Univ.-Prof. Dr. G.R. Fink)
2005 – 2007: Postdoctoral fellowship at the National Institute for Neurological Diseases and Stroke (NINDS/NIH) in Bethesda, MD, USA (Head: Dr. R. McKay)
2004 – 2005: Postdoctoral fellowship at the Max-Planck-Institute for Neurological Research in Cologne (Head: Prof. Dr. A. Jacobs)
2004: Full ‚Approbation’ as a physician
2002 – 2004: Internship in clinical neurology (‘Ärztin im Praktikum’) at the Department of Neurology, University Hospital of Cologne (Director: Prof. Dr. W.F. Heiss)
2003: Doctoral thesis at the Institute of Anatomy: “Expression of GAP-43 and neuregulin receptors in Schwann cells of the facial nerve after delayed hypoglossal-facial crossed nerve suture in rats” (Advisor: Prof. Dr. W.F. Neiss; grade: ‘magna cum laude’)
1996 – 2002: Medical school at the University of Cologne

Awards, distinctions and professional activities

2011: Nominated for the federal award in the initiative ‘Germany – Land of Ideas’, founded by the federal government and the Federation of German Industries (BDI)
2010: Best Publication of 2010, awarded by the Medical Faculty of the University of Cologne
2005 – 2007: Scholarship awarded by the Deutscher Akademischer Austausch-Dienst
2005: Scholarship awarded by the Max-Planck-Society

Selected publications

Braun R, Klein R, Walter HL, Ohren M; Freudenmacher L, Getachew K, Ladwig A, Luelling J, Neumaier B, Endepols H, Graf R, Hoehn M, Fink GR, Schroeter M, Rueger MA: Transcranial direct current stimulation accelerates recovery of function, induces neurogenesis and recruits oligodendrocyte precursors in a rat model of stroke. Exp Neurol (2016); 279: 127-136.
 
Backes B, Walberer M, Ladwig A, Rueger MA, Neumaier B, Endepols H, Hoehn M, Fink GR, Schroeter M, Graf R: Glucose consumption of inflammatory cells masks metabolic deficits in the brain. NeuroImage (2016); 128: 54-62.
 
Rabenstein M, Vay SU, Flitsch LJ, Fink GR, Schroeter M, Rueger MA: Osteopontin directly modulates cytokine expression of primary microglia and increases their survival. J Neuroimmunol. (2016) 15;299:130-138.

Rabenstein M, Hucklenbroich J, Willuweit A, Ladwig A, Fink GR, Schroeter M, Langen KJ, Rueger MA: Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4. Stem Cell Res Ther (2015); 6(1): 99.

Keuters MH, Aswendt M, Tennstaedt A, Wiedermann D, Pikhovych A, Rotthues S, Fink GR, Schroeter M, Hoehn M, Rueger MA: Transcranial direct current stimulation promotes the mobility of engrafted neural stem cells in the rat brain. NMR Biomed (2015); 28(2): 231-239.
 
Hucklenbroich J, Klein R, Neumaier B, Graf R, Fink GR, Schroeter M, Rueger MA: Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther (2014); 5: 100.
 
Walberer M, Backes H, Rueger MA, Neumaier B, Endepols H, Hoehn M, Fink GR, Schroeter M, Graf R: Potential of early FDG-PET for identifying hypo-perfusion and predicting fate of tissue in a rat embolic stroke model. Stroke (2012); 43(1):193-198.
 
Rueger MA, Keuters MH, Walberer M, Braun R, Klein R, Sparing R, Fink GR, Graf R, Schroeter M: Multi-session transcranial direct current stimulation (tDCS) elicits inflammatory and regenerative processes in the rat brain. PLoS ONE (2012); 7(8): e43776.
 
Rueger MA, Muesken S, Walberer M, Jantzen SU, Schnakenburg K, Backes H, Graf R, Neumaier B, Hoehn M, Fink GR, Schroeter M: Effects of minocycline on endogenous neural stem cells after experimental stroke. Neuroscience (2012); 215: 174-183.
 
Rueger MA, Backes H, Walberer M, Neumaier B, Ullrich R, Simard ML, Emig B, Fink GR, Hoehn M, Graf R, Schroeter M: Noninvasive imaging of endogenous neural stem cell mobilization in vivo using positron emission tomography. J Neurosci. (2010) 5;30(18):6454-60.