Prof. Dr. rer. nat. Peter Nürnberg - Curriculum Vitae

Education and professional career

since 2012: Member of the Scientific Board for HPC, University of Cologne
2009 - 2012: Member of the Scientific Advisory Board of the Leibnitz-Institut für Arterioskleroseforschung e.V. (lifa), Münster
since 2005: Founding director of the Cologne Center for Genomics (CCG), University of Cologne
since 2004: C4-Professor of Genomics, University of Cologne
since 2004: President of the ‘Arbeitsgemeinschaft für Gendiagnostik e.V.’ (AGD)
2004 - 2008: Coordinator of the National Genotyping Platform of the NGFN
since 2003: Member of the Scientific Board of the Tumor Bank Ovarian Cancer
2000 - 2004: Head of the Gene Mapping Center (GMC), Max Delbrück Center for Molecular Medicine, Berlin-Buch
1997: postdoctoral lecture qualification (Habilitation) in Human Genetics, Charité Berlin
1990: Visiting research investigator, AG Epplen, Max-Planck-Institute of Psychiatry, Martinsried
1987 - 2000: Research associate and group leader, Institute of Medical Genetics, Charité, Humboldt-University, Berlin
1984 - 1987: Postdoctoral research fellow, Central Institute of Molecular Biology, Academy of Sciences of the GDR, Berlin-Buch
1985: Humboldt Award
1984: Postgraduate studies in Theoretical Medicine: Fach-Biochemiker der Medizin
1984: Ph.D., Biology / Biochemistry, Humboldt University, Berlin
1981: Diploma in Biology, Humboldt University, Berlin
1979 - 1981: Goethe scholarship of the Humboldt University, Berlin

Selected publications

George J, Lim JS, Jang SJ,…, Nürnberg P, Reinhardt C, Perner S, Heukamp L, Büttner R, Haas SA, Brambilla E, Peifer M, Sage J, Thomas RK. Comprehensive genomic profiles of small cell lung cancer. Nature. 2015, Aug 6;524(7563):47-53. doi: 10.1038/nature14664.

Lal D, Ruppert AK, Trucks H,…, Nürnberg P; EPICURE Consortium, Sander T. Burden analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic generalised epilepsies. PLoS Genet. 2015, May 7;11(5):e1005226. doi: 10.1371/journal.pgen.1005226.

Hussain MS, Battaglia A, Szczepanski S,…, Nürnberg P. Mutations in CKAP2L, the human ortholog of the mouse Radmis gene, cause Filippi syndrome. Am J Hum Genet. 2014 Nov 6;95(5):622-32. doi: 10.1016/j.ajhg.2014.10.008.

Schubert J, Siekierska A, Langlois M,…, Nürnberg P, Crawford AD, Esguerra CV, Weber YG, Lerche H. Mutations in STX1B encoding a presynaptic protein cause fever-associated epilepsy syndromes. Nat Genet. 2014, Nov. 2. doi:10.1038/ng.3130.

Martin C-A,* Ahmad I,* Klingseisen A,…, Nürnberg P**, Jackson AP**. Mutations in PLK4, a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Nat Genet. 2014, Oct 26. doi: 10.1038/ng.3122.

Hussain MS, Baig SM, Neumann S, Peche VS, Szczepanski S, Nürnberg G, Tariq M, Jameel M, Khan TN, Fatima A, Malik NA, Ahmad I, Altmüller J, Frommolt P, Thiele H, Höhne W, Yigit G, Wollnik B, Neubauer BA, Nürnberg P**, Noegel AA**. CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 2013, Dec 20;22(25):5199-214.

Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA**, Nürnberg P**. A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. Am J Hum Genet. 2012, 90, 871-878.

Weiss J, Sos ML, Seidel D, …, Nürnberg P, Perner S, Thomas RK. Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med. 2010, Dec 15;2(62):62ra93.

Rutsch F, Gailus S, Miousse IR, Suormala T, Sagné C, Toliat MR, Nürnberg G, Wittkampf T, Buers I, Sharifi A, Stucki M, Becker C, Baumgartner M, Robenek H, Marquardt T, Höhne W, Gasnier B, Rosenblatt DS, Fowler B, Nürnberg P. Identification of a putative lysosomal cobalamin exporter
altered in the cblF defect of vitamin B12 metabolism. Nat Genet. 2009, 41:234-239.

Budde BS, Namavar Y, Barth PG,…, Nürnberg P**, Baas F**. tRNA splicing endonuclease mutations cause pontocerebellar hypoplasia. Nat Genet. 2008, 40:1113-1118. ** shared senior authorship.