Prof. Dr. rer. nat. Angelika A Noegel - Curriculum Vitae

Education and professional career

2007 - 2009: Vice president vbio (Verband Biologie, Biowissenschaften and Biomedizin in Deutschland)
2006 - 2007: Vice president, vdbiol
2005 - 2006: President, German Society for Cell Biology (DGZ)
2004 - 2007: Vice president, Verbund biowissenschaftlicher und biomedizinischer Gesellschaften (vbbm)
2002 - 2005: Vice president, German Society for Cell Biology (DGZ)
2000 - 2008: Panel member, Study Section Molecular Biology, DFG
2000: Elected member, European Molecular Biology Organisation
1997: C4-Professor and Head, Institute of Biochemistry I, Medical Faculty, University of Cologne
1983 - 1997: Research associate and group leader, Max-Planck-Institute for Biochemistry, Martinsried, Germany
1979 - 1983: Research associate, Laboratory of Bacteriology and Immunology, The Rockefeller University, New York, USA
1979: PhD, Institute of Microbiology, University of Würzburg, Germany

Selected publications

Stumpf M, Müller R, Gaßen B, Wehrstedt R, Fey P, Karow MA, Eichinger L, Glöckner G, Noegel AA. A Tripeptidyl peptidase 1 is a binding partner of GPHR (Golgi pH regulator) in Dictyostelium. Disease Models & Mechanisms 2017, doi: 10.1242/dmm.029280.

Szczepanski S, Hussain MS, Sur I, Altmüller J, Thiele H, Abdullah U, Waseem SS, Moawia A, Nürnberg G, Noegel AA, Baig SM, Nürnberg P. A novel homozygous splicing mutation of CASC5 causes primary microcephaly in a large Pakistani family. Hum Genet 2016, 135, 157-170.

Li P, Noegel AA. Inner nuclear envelope protein SUN1 plays a prominent role in mammalian mRNA export. Nucleic Acids Res 2015, 43, 9874-9888.

Hussain MS, Battaglia A, Szczepanski S, ….. Noegel A., Newman WG, Nürnberg P. Mutations in CKAP2L, the Human Ortholog of the Mouse Radmis Gene, Cause Filippi Syndrome. Am J Hum Genet 2014, 95, 622-632.

Martin CA, Ahmad I, Klingseisen A,…, Noegel AA, Baig SM, Nürnberg P, Jackson AP. Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Nat Genet. 2014, 46, 1283-1292.

Swaminathan K, Müller-Taubenberger A, Faix J, Rivero F, Noegel AA. A Cdc42- and Rac-interactive binding (CRIB) domain mediates functions of coronin. Proc Natl Acad Sci USA. 2014, 111, E25-33.

Hussain MS, Baig SM, Neumann S, Peche VS, Szczepanski S, Nürnberg G, Tariq M, Jameel M, Khan TN, Fatima A, Malik NA, Ahmad I, Altmüller J, Frommolt P, Thiele H, Höhne W, Yigit G, Wollnik B, Neubauer BA, Nürnberg P, Noegel AA. CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 2013, 22, 5199-5214.

Peche VS, Holak TA, Burgute BD, Kosmas K, Kale SP, Wunderlich FT, Elhamine F, Stehle R, Pfitzer G, Nohroudi K, Addicks K, Stöckigt F, Schrickel JW, Gallinger J, Schleicher M, Noegel AA. Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy. Cell Mol Life Sci. 2013, 70, 527-543.

Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P. A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. Am J Hum Genet. 2012, 90, 871-878.

Shina MC, Unal C, Eichinger L, Müller-Taubenberger A, Schleicher M, Steinert M, Noegel AA. A Coronin7 homolog with functions in actin-driven processes. J Biol Chem. 2010, Mar 285, 9249-9261.
Mondal S, Bakthavatsalam D, Steimle P, Gassen B, Rivero F, Noegel AA. Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions. J Cell Biol. 2008, 181, 747-760.

Lüke Y, Zaim H, Karakesisoglou I, Jaeger VM, Sellin L, Lu W, Schneider M, Neumann S, Beijer A, Munck M, Padmakumar VC, Gloy J, Walz G, Noegel AA. Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. J Cell Sci. 2008, 121, 1887-1898.

Bakthavatsalam D, Brazill D, Gomer RH, Eichinger L, Rivero F, Noegel AA. A G protein-coupled receptor with a lipid kinase domain is involved in cell-density sensing. Curr Biol. 2007, 17, 892-897.

Eichinger L, Pachebat JA, Glöckner G,…, Noegel AA, Barrell B, Kuspa A. The genome of the social amoeba Dictyostelium discoideum. Nature. 2005, 435, 43-57.