Prof. Dr. med. Stephan Baldus - Curriculum Vitae

Education and professional career

since 2017: Member, Programme Committee, German Society of Cardiology
2015 - 2017: Chair, Commission of Clinical Cardiology, German Society of Cardiology
since 2014: Member, Education Committee, European Society of Cardiology
2013 - 2017: Member, Commission of Clinical Cardiology, German Society of Cardiology
since 2012: Professor and Chair, Department of Internal Medicine and Cardiology,
University of Cologne
2010 - 2012: Associate Professor and Vice Chair, Department of Cardiology, University Heart Center Hamburg
2004/2007/2012: Board approvals Internal Medicine / Cardiology / Intensive Care Medicine
2010: Paul Schölmerich Award of the German Society of Internal Medicine
2005 - 2011: Teacher of the Year, University of Hamburg, Faculty of Medicine
2006 - 2009: Assistant Professor, Department of Cardiology, University Heart Center Hamburg
2008: Albert Fraenkel Award of the German Society of Cardiology
2001 - 2006: Resident in Medicine, Department of Cardiology, University Heart Center Hamburg
1999 - 2001: Postdoctoral Fellow, Center for Free Radical Biology, University of Alabama at Birmingham, AL, USA

Selected publications

Mollenhauer M, Friedrichs K, Lange M, Gesenberg M, Remane L, Kerkenpaß C, Krause J, Schneider J, Ravekes T, Maass M, Halbach M, Peinkofer G, Saric T, Mehrkens D, Adam M, Deuschl F, Lau D, Geertz B, Manchanda K, Eschenhagen T, Kubala L, Rudolph TK, Wu Y, Tang WHV, Hazen SL, Baldus S, Klinke A, Rudolph V. Myeloperoxidase mediates postischemic arrhythmogenic ventricular remodeling. Circ Res. 2017 Apr 12. pii: CIRCRESAHA.117.310870.

Adam M, Meyer S, Knors H, Klinke A, Radunski UK, Rudolph TK, Rudolph V, Spin JM, Tsao PS, Costard-Jäckle A, Baldus S. Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure. Sci Rep. 2015, 5: 9704.

Adam M, Gajdova S, Kolarova H, Kubala L, Lau D, Geisler A, Ravekes T, Rudolph V, Tsao PS, Blankenberg S, Baldus S, Klinke A. Red blood cells serve as intravascular carriers of myeloperoxidase. J Mol Cell Cardiol 2014, 74: 353-363.

Friedrichs K, Adam M, Remane L, Mollenhauer M, Rudolph V, Rudolph TK, Andrié RP, Stöckigt F, Schrickel JW, Ravekes T, Deuschl F, Nickenig G, Willems S, Baldus S, Klinke A. Induction of atrial fibrillation by neutrophils critically depends on CD11b/CD18 integrins. PLoS One. 2014, 9: e89307.

Klinke A, Möller A, Pekarova M, Ravekes T, Friedrichs K, Berlin M, Scheu KM, Kubala L, Kolarova H, Ambrozova G, Schermuly RT, Woodcock SR, Freeman BA, Rosenkranz S, Baldus S, Rudolph V, Rudolph TK. Protective effects of 10-Nitro-Oleic acid in a hypoxia-induced murine model of pulmonary hypertension. Am J Respir Cell Mol Biol. 2014, Feb 12 (Epub ahead of print).

Klinke A, Nussbaum C, Kubala L, Friedrichs K, Rudolph TK, Rudolph V, Paust HJ, Schröder C, Benten D, Lau D, Szocs K, Furtmüller PG, Heeringa P, Sydow K, Duchstein HJ, Ehmke H, Schumacher U, Meinertz T, Sperandio M, Baldus S. Myeloperoxidase attracts neutrophils by physical forces. Blood. 2011, 117: 1350-1358.

Rudolph V, Andrié R, Rudolph TK, Friedrichs K, Klinke A, Hirsch-Hoffmann B, Sydow K, Schwoerer A, Lau D, Didiér M, Szoecs K, Schrickel J, Treede H, Hämmerling I, Wenzel U, Lewalter T, Nickenig G, Zimmermann W, Böger R, Reichenspurner H, Meinertz T, Ehmke H, Willems S, Baldus S. Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. Nat Med. 2010, 16: 470-474.

Baldus S, Rudolph V, Roiss M, Ito WD, Rudolph TK, Eiserich JP, Sydow K, Lau D, Szocs K, Klinke A, Kubala L, Berglund L, Schrepfer S, Deuse T, Haddad M, Risius T, Klemm H, Reichenspurner HC, Meinertz T, Heitzer T. Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase. Circulation. 2006, 113: 1871-1878.

Lau D, Mollnau H, Eiserich JP, Freeman BA, Daiber A, Gehling UM, Brümmer J, Münzel T, Heitzer T, Meinertz T, Baldus S. Myeloperoxidase mediates Neutrophil Activation by Association with CD 11b/CD18 Integrins. Proc Natl Acad Sci USA. 2005, 102: 431-436.

Eiserich JP*, Baldus S*, Brennan ML, Ma W, Zhuang C, Tousson A, Castro L, Lusis AJ, White CR, Freeman BA. Myeloperoxidase: a leukocyte derived vascular NO oxidase. Science. 2002, 296: 2391-2394. *equal contribution.

Baldus S, Eiserich JP, Mani A, Castro L, Figueroa, M, Chumley P, Ma W, Tousson A, White RC, Bullard DC, Brennan ML, Lusis AJ, Moore KP, Freeman BA. Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. J Clin Invest. 2001, 108:1759–1770.