Dr. rer. nat. Martin Mollenhauer - Curriculum Vitae

Education and professional career

since 2014: Group leader, AG Prof. Baldus, Heartcenter, University Hospital Cologne, Germany
2013 - 2014: Postdoc, AG Prof. Baldus, Heartcenter, University Hospital Cologne, Germany
2012: Postdoc, University Hospital Heidelberg and German Cancer Research Center (DKFZ), AG Prof. J. Weitz, Heidelberg, Germany
2012: Ph.D. (Dr. rer. nat.): „Impact of Prolyl-4-Hydroxylase Deficiency on Liver Regeneration and Sepsis”, Ruprecht-Karls-University Heidelberg, Germany
2008 - 2012: Ph.D. student: University Hospital Heidelberg and German Cancer Research Center (DKFZ), AG Prof. J. Weitz, Heidelberg, Germany
2007: Master of Sciences in „Molecular Biotechnology“: „Self-cleaving 2A-like Sequences“, BASF Plant Science GmbH and Ruprecht-Karls-University Heidelberg, Germany
2001 - 2007: Academic studies in Molecular Biotechnology (BSc und MSc), Ruprecht-Karls-University Heidelberg, Germany
2000: Abitur, EMA – Gymnasium, Herzberg am Harz, Germany

Awards, distinctions and professional activities

2017 - 2019: CMMC funding B2: Inflammatory pathways propagating ventricular arrhythmia - the role of myeloperoxidase for postischemic pro-arrhythmic remodeling
2016 - 2017: Deutsche Herzstiftung, Grant No.: K/27/15: Welchen Einfluss hat MPO auf die inflammatorische Aktivierung von Monozyten bei der Herzinsuffizienz?
2014 - 2015: Köln Fortune, Grant No.: 244/2014: Die Rolle der MPO für die Alterung und genomische Instabilität von Endothelzellen in vitro

Selected publications

Mollenhauer M, Friedrichs K, Lange M, Gesenberg J, Remane L, Kerkenpaß C, Krause J, Schneider J, Ravekes T, Maass M, Halbach M, Peinkofer G, Saric T, Mehrkens D, Adam M, Deuschl FG, Lau D, Geertz B, Manchanda K, Eschenhagen T, Kubala L, Rudolph TK, Wu Y, Tang WW, Hazen SL, Baldus S, Klinke A, Rudolph V.: Myeloperoxidase Mediates Postischemic Arrhythmogenic Ventricular Remodeling. Circ Res. 2017 Apr 12. pii: CIRCRESAHA.117.310870.

Harnoss JM, Platzer LK, Burhenne J, Radhakrishnan P, Cai J, Strowitzki MJ, Weiss J, Ritter AS, Mollenhauer M, Schmidt T, Ulrich A, Haefeli WE, Schneider M.: Prolyl Hydroxylase Inhibition Enhances Liver Regeneration Without Induction of Tumor Growth. Ann Surg. 2016 Mar 8.

Radhakrishnan P, Ruh N, Harnoss JM, Kiss J, Mollenhauer M, Scherr AL, Platzer LK, Schmidt T, Podar K, Opferman JT, Weitz J, Schulze-Bergkamen H, Koehler BC, Ulrich A, Schneider M.: Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells. Cancer Res. 2016 Apr 15;76(8):2219-30.

Tiyerili V, Camara B, Becher MU, Schrickel JW, Lütjohann D, Mollenhauer M, Baldus S, Nickenig G, Andrié RP.: Neutrophil-derived myeloperoxidase promotes atherogenesis and neointima formation in mice.: Int J Cardiol. 2016 Feb 1;204:29-36.

Rudolph TK, Ravekes T, Klinke A, Friedrichs K, Mollenhauer M, Pekarova M, Ambrozova G, Martiskova H, Kaur JJ, Matthes B, Schwoerer A, Woodcock SR, Kubala L, Freeman BA, Baldus S, Rudolph V.: Nitrated fatty acids suppress angiotensin II-mediated fibrotic remodelling and atrial fibrillation. Cardiovasc Res. 2016 Jan 1;109(1):174-84.

Isayev O, Rausch V, Bauer N, Liu L, Fan P, Zhang Y, Gladkich J, Nwaeburu CC, Mattern J, Mollenhauer M, Rückert F, Zach S, Haberkorn U, Gross W, Schönsiegel F, Bazhin AV, Herr I.: Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine. Oncotarget. 2014 Jul 15;5(13):5177-89.

Friedrichs K, Adam M, Remane L, Mollenhauer M, Rudolph V, Rudolph TK, Andrié RP, Stöckigt F, Schrickel JW, Ravekes T, Deuschl F, Nickenig G, Willems S, Baldus S, Klinke A.: Induction of atrial fibrillation by neutrophils critically depends on CD11b/CD18 integrins. PLoS One. 2014 Feb 18;9(2):e89307.

Mollenhauer M, Kiss J, Dudda J, Kirchberg J, Rahbari N, Radhakrishnan P, Niemietz T, Rausch V, Weitz J, Schneider M.: Deficiency of the oxygen sensor PHD1 augments liver regeneration after partial hepatectomy. Langenbecks Arch Surg. 2012 Dec;397(8):1313-22.

Kiss J*, Mollenhauer M*, Walmsley SR, Kirchberg J, Radhakrishnan P, Niemietz T, Dudda J, Steinert G, Whyte MK, Carmeliet P, Mazzone M, Weitz J, Schneider M.: Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis. J Immunol. 2012 Aug 15;189(4):1955-65.