Prof. Dr. rer. nat. Björn Schumacher - Curriculum Vitae

Education and professional career

since 2014: President of the German Society for Aging Research (DGfA)
since 2014: Member of the scientific advisory board, Frankfurter Zukunftsrat (Future Think Tank)
since 2013: W3-Professor for Genome Stability in Aging and Disease, University of Cologne
2012 -2016: Coordinator of the initial training network on chronic DNA damage responses in Aging (FP7-ITN-CodeAge; www.itn-codeage.eu)
since 2012: Scientific coordinator of Research Area C (DNA damage response) within the Excellence Cluster CECAD
2011 - 2017: European Research Council (ERC) Starting Independent Researcher Grant
2009: Innovation Prize of the State of North-Rhine Westphalia
2009 - 2013: Independent junior research group leader in the Cologne Excellence Cluster ‘Cellular Stress Responses in Aging-Associated Diseases’ (CECAD), University of Cologne
2005 - 2008: EMBO long-term postdoctoral Fellowship and Marie Curie Intra-European Fellowship
2004 - 2008: Postdoctoral Fellow with Prof. Jan Hoeijmakers, Department of Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
2004: PhD degree, Max-Planck-Institute for Biochemistry and Ludwig Maximilian University, Munich
2000 - 2004: PhD student with Dr. Anton Gartner, Department of Cell Biology, Max-Planck-Institute for Biochemistry, Martinsried, Germany
1999 - 2000: Research stipend, Cold Spring Harbor Laboratory and Tuition scholarship, SUNY Stony Brook, NY, USA
1999 - 2000: PhD thesis work with Dr. Michael Hengartner and Dr. Anton Gartner, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA
1999: Master of Arts in Biological Sciences; Dr. Dafna Bar-Sagi, Department of Molecular Genetics and Microbiology, SUNY Stony Brook
1998 - 1999: Visiting scholar, State University of New York (SUNY) at Stony Brook, USA
1995 - 1998: Studies in Biology, University of Konstanz, Germany

Selected publications

Ackermann L, Schell M, Pokrzywa W, Kevei É, Gartner A, Schumacher B#, Hoppe T#. E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis. Nat Struct Mol Biol. 2016 Nov;23(11):995-1002. doi: 10.1038/nsmb.3296. (#co-corresponding authors)

Babu V, Schumacher B. A C. elegans homolog for the UV-hypersensitivity syndrome disease gene UVSSA. DNA Repair (Amst). 2016 Mar 25;41:8-15. doi: 10.1016/j.dnarep.2016.03.008.

Mueller M, Castells-Roca L, Babu V, Ermolaeva MA, Müller RU, Frommolt P, Williams AB, Greiss S, Schneider JI, Benzing T, Schermer B, Schumacher B. DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage. Nat Cell Biol. 2014, Nov
24:16(12):1168–1179. doi: 10.1038/ncb3071.

Babu V, Hofmann K, Schumacher B. A C. elegans homolog of the Cockayne syndrome complementation group A gene. DNA Repair. 2014, Dec:24:57-62. doi: 10.1016/j.dnarep.2014.09.012.

Ermolaeva MA, Schumacher B. Insights from the worm: The C. elegans model for innate immunity. Semin Immunol. 2014, May 20. pii: S1044-5323(14)00051-7. doi: 10.1016/j.smim.2014.04.005.
Wolters S, Ermolaeva M, Bickel J, Fingerhut J, Khanikar J, Chan R, Schumacher B. Loss of C. elegans BRCA1 promotes genome stability during replication in smc-5 mutants. Genetics. 2014, Apr;196(4):985-99. doi: 10.1534/genetics.113.158295.

Ermolaeva M and Schumacher B. Systemic DNA damage responses: Organismal adaptations to genome instability. Trends Genet. 2014, Mar;30(3):95-102. doi: 10.1016/j.tig.2013.12.001.

Behrens A, van Deursen J, Rudolph KL, Schumacher B. Impact of genomic damage and aging on stem cell function. Nat Cell Biol. 2014, Feb 28;16(3):201-7. doi: 10.1038/ncb2928.

Ermolaeva MA, Segref A, Dakhovnik A, Ou HL, Schneider JI, Utermöhlen O, Hoppe T, Schumacher B. DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance. Nature. 2013, Sep 19;501(7467):416-20. doi: 10.1038/nature12452.

Reinhardt HC, Schumacher B. The p53 network: Cellular and systemic DNA damage responses in aging and cancer. Trends Genet. 2012 Mar;28(3):128-36.

Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LHF, van der Horst GTJ, Brüning JC, Niessen CM, Hoeijmakers JHJ and Schumacher B. Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nat Cell Biol. 2009, May;11(5):604-15.

Schumacher B, van der Pluijm I, Moorhouse MJ, Rasile Robinson A, Suh Y, Breit TM, van Steeg H, Niedernhofer LJ, van Ijcken W, Bartke A, Spindler SR, Hoeijmakers JHJ, van der Horst GTJ and Garinis GA. Delayed and accelerated aging share common longevity assurance mechanisms. PLoS Genet. 2008, Aug 15;4(8):e1000161.