Dear CMMC Members
Dear interested members of the Medical and Science Faculties

It is a great pleasure for us to welcome you and your group members as well as interested members of the Medical and Science Faculties to the CMMC Annual Retreat taking place from Feb. 21 - 22, 2018 at the Lecture Hall of the MPI for Biology of Ageing. The retreat starts on Wednesday - Feb. 21, 2018 at 10 a.m. and ends on Thursday Feb. 22, 2018 at about 1.00 p.m.

For organizational reasons, online registration is required. Please register: http://cmmc-registration.uni-koeln.de/annualretreat/

We look forward to welcoming you to a highly interactive meeting.

With best regards

Thomas Benzing
Chair of the CMMC and the CMMC EC Members

Program: CMMC Report - Short Talks - CMMC Lecture - Poster Session

Over 58 research groups, six core facilities, the IPMM program complemented by additional research related activities are supported and integrated in the CMMC.

Based on a rotation system, every year a limited number of CMMC project groups are invited to present a progress report. To further facilitate the networking and exchange within the CMMC, all CMMC project leaders of the different CMMC funding programs and heads of the core facilities are invited to present a poster during the CMMC poster sessions. The poster sessions will take place during the coffee and lunch breaks in the foyer directly in front of the Lecture Hall at the venue.

To further facilitate the scientific exchange the CMMC Annual Retreat is open to all members that have a strong interest in biomedical research of the Medical and Science Faculties as well as for the members of the associated Max Planck Institutes. For the CMMC members, the participation in the Annual Retreat is considered with highest priority.

CMMC Lecture: Prof. Dr. Clemens A Schmitt (Berlin, DE)

We are delighted to announce that Prof. Dr. Clemens A. Schmitt (Dept. of Hematology, Oncology and Tumor Biology - Charité-University Medical Center and MDC for Molecular Medicine, Berlin) has accepted our invitation to participate in the Annual Retreat as honorary lecturer of the CMMC Lecture.

The CMMC Lecture "Senescence in caner: Restore, prevent or eliminate?" will take place on Feb. 21, 2018 at 5.00 p.m.



Program - Annual Retreat 2018

9.00 - 10.00. a.m.

Meeting of the CMMC Executive Board (for members of the EC Board only)

10.00 - 10.30 a.m.

Welcome address - introduction - CMMC progress report (General assembly part I)
Thomas Benzing - Chair of the Center for Molecular Medicine Cologne

CMMC Junior Research Groups

10.30 - 10.50 a.m.

JRG VII - Topological disruption of enhancers landscapes as an etiological mechanism of human congenital disease
Alvaro Rada-Iglesias - Laboratory of Developmental Genomics, CMMC

10.50 - 11.10 p.m.

JRG IX - Targeting cilium checkpoint to perturb glioma stem cells proliferation
Jay Gopalakrishnan - Laboratory of Centrosome and Cytoskeleton Biology, CMMC

11.10 - 11.30 p.m

JRG VIII - Impact of a rare progeroid syndrome onto genomic structure and function
Argyris Papantonis - Laboratory of Systems Biology of Chromatin, CMMC

011.30 - 12.00 p.m.

Coffee Break - with poster presentation

Research Area C:
Molecular mechanisms and metabolic control of tissue degeneration and regeneration

12.00 - 12.20 p.m.

C 5 / CAP 1 - Mitochondrial energetics and its contribution to podocyte function
Paul Brinkkötter - Department II of Internal Medicine

12.20 - 12.40 p.m.

C 7 - TOR signalling in epidermal homeostasis
Sabine Eming1 / Maria Leptin2 - Department of Dermatology1 / Institute for Genetics2

12.40 - 1.00 p.m.

CAP 10 - Molecular mechanisms of pulmonary alveolar and vascular development
Miguel A Alejandre Alcazar - Department of Children and Adolescent Medicine

1.00 - 2.30 p.m.

Lunch - with poster presentation

2.30 - 2.50 p.m.

C 11 - Investigating the roles of CSNK2B and LEF1 mutations in the etiology of Filippi syndrome and ectrodactyly ectodermal dysplasia
Muhammad Sajid Hussain1 / Angelika A Noegel1 / Peter Nürnberg2 - Institute for Biochemistry I1 / Cologne Center for Genomics2

2.50 - 3.10 p.m.

C 12 - APEX-based proximity labeling identifies actin binding proteins as new components of primary cilia
Bernhard Schermer1 / Max C Liebau2 - Department II of Internal Medicine1 / Department of Children and Adolescent Medicine2

3.10 - 3.30 p.m.

General assembly part II
Thomas Benzing - Chair of the Center for Molecular Medicine Cologne

3.30 - 3.45 p.m.

Coffee Break - with poster presentation

3.45 - 4.05 p.m.

C 13 - The mechanism of nitrite-dependent NO synthesis by sulfite oxidase
Guenter Schwarz - Institute for Biochemistry

4.05 - 4.25 p.m.

C 14 - Extracellular microfibrillar systems in disease pathogenesis
Gerhard Sengle / Raimund Wagner  / Mats Paulsson - Institute for Biochemistry II

4.25 - 4.45 p.m.

C 16 - Unraveling the molecular and cellular mechanism underlying spinal muscular atrophy by use of genetic modifiers
Brunhilde Wirth - Institute for Human Genetics

4.45 - 5.00 p.m.

Coffee Break - with poster presentation

5.00 - 6.00 p.m.
CMMC Lecture

Senescence in cancer: Restore, prevent or eliminate?
Clemens Schmitt

Charité Universitätsmedizin and Max-Delbrück-Center for Molecular Medicine, Berlin, DE



6. 00 - 6.15 p.m.

Change of location for the CMMC Dinner to the CMMC Research Building (Robert-Koch-Str. 21)

from 6.15 p.m.

Reception followed by the CMMC Dinner

Research Area A:
Mechanisms of tumor development: intrinsic and extrinsic control of cell proliferation and tissue invasion

9.00 - 9.20 a.m.

A 6 - Polarity networks in melanocyte function and melanoma cell plasticity
Sandra Iden - CECAD Cologne

9.20 - 9.40 a.m.

A 1 - The multifaceted function of the lysine-specific histone demethylase 1 in lung cancer
Margarethe Odenthal / Reinhard Büttner - Institute for Pathology

9.40 - 10.00 a.m.

A 4 - Prel. title: The multiple facets of the type II transmembrane serine protease ST14 and hypotonic stress during carcinogenesis in fish and mammals
Matthias Hammerschmidt - Biocenter, Institute for Zoology

10.00 - 10.20 a.m. 

Coffee break with poster session

10.20 - 10.40 a.m. 

A 9 - Modeling Myd88-driven lymphoma
H Christian Reinhardt1 / Martin Peifer2  - Department I for Internal Medicine1 / Department of Translational Genomics2

10.40 - 11.00 a.m.

A 10 - Epigenetic mechanisms of genomic instability and therapy resistance in cancer
Michal-Ruth Schweiger - Laboratory for Epigenetics and Tumorgenetics

11.00 - 11.20 a.m.

assoc. RG - title to be announced

11.20 - 11.40 a.m.

Coffee Break - with poster presentation

Research Area B:
Principles of immunity, inflammation and infection

11.40 - 12.00 p.m.

CAP 12 - Tumor-specific endogenous immune response in esophago-gastric adenocarcinoma
Hans A Schlößer - Department of General, Visceral and Cancer Srugery

12.00 - 12.20 p.m.

B 2 - Inflammatory pathways propagating ventricular arrhythmia  - the role of myeloperoxidase for postischemic pro-arrhythmic remodeling
Stephan Baldus / Martin Mollenhauer / Volker Rudolph - Department III of Internal Medicine

12.20 - 12.40 p.m.

B 1 - Prel. title: Metabolic addiction and reprogramming of an anti-tumor T cell response
Hinrich Abken - Department I of Internal Medicine

12.40 - 1.00 p.m.

Final discussion and leave-taking
Thomas Benzing - Chair of the CMMC