Summary of articles published by CMMC members in 2014

Selected publications related to CMMC-projects are listed in alphabetical order by the first author published in 2014.

  1. Ackermann S, Kocak H, Hero B, Ehemann V, Kahlert Y, Oberthuer A, Roels F, Theissen J, Odenthal M, Berthold F, and Fischer M (2014). Foxp1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma. BMC cancer 14, 840.

  2. Altmuller J, Budde BS, and Nürnberg P (2014). Enrichment of target sequences for next-generation sequencing applications in research and diagnostics. Biol Chem 395, 231-237.

  3. Anand R, Wai T, Baker MJ, Kladt N, Schauss AC, Rugarli EI, and Langer T (2014). The i-aaa protease yme1l and oma1 cleave opa1 to balance mitochondrial fusion and fission. J Cell Biol 204, 919-929.

  4. Andree M, Seeger JM, Schull S, Coutelle O, Wagner-Stippich D, Wiegmann K, Wunderlich CM, Brinkmann K, Broxtermann P, Witt A, Fritsch M, Martinelli P, Bielig H, Lamkemeyer T, Rugarli EI, Kaufmann T, Sterner-Kock A, Wunderlich FT, Villunger A, Martins LM, Krönke M, Kufer TA, Utermöhlen O, and Kashkar H (2014). Bid-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against shigella. EMBO 32, 2171-87.

  5. Bahat A, Perlberg S, Melamed-Book N, Lauria I, Langer T, and Orly J (2014). Star enhances transcription of genes encoding the mitochondrial proteases involved in its own degradation. Mol Endocrinol 28, 208-224.

  6. Baker MJ, Lampe PA, Stojanovski D, Korwitz A, Anand R, Tatsuta T, and Langer T (2014). Stress-induced oma1 activation and autocatalytic turnover regulate opa1-dependent mitochondrial dynamics. EMBO J 33, 578-593.

  7. Basmanav FB, Oprisoreanu AM, Pasternack SM, Thiele H, Fritz G, Wenzel J, Grosser L, Wehner M, Wolf S, Fagerberg C, Bygum A, Altmüller J, Rutten A, Parmentier L, El Shabrawi-Caelen L, Hafner C, Nürnberg P, Kruse R, Schoch S, Hanneken S, and Betz RC (2014). Mutations in poglut1, encoding protein o-glucosyltransferase 1, cause autosomal-dominant dowling-degos disease. Am J Hum Genes 94, 135-143.

  8. Beck BB, Phillips JB, Bartram MP, Wegner J, Thoenes M, Pannes A, Sampson J, Heller R, Gobel H, Koerber F, Neugebauer A, Hedergott A, Nürnberg G, Nürnberg P, Thiele H, Altmüller J, Toliat MR, Staubach S, Boycott KM, Valente EM, Janecke AR, Eisenberger T, Bergmann C, Tebbe L, Wang Y, Wu Y, Fry AM, Westerfield M, Wolfrum U, and Bolz HJ (2014). Mutation of poc1b in a severe syndromic retinal ciliopathy. Hum Mutat 35, 1153-1162.

  9. Becker AK, Mikolajek H, Paulsson M, Wagener R, and Werner JM (2014). A structure of a collagen VI VWA domain displays N and C termini at opposite sides of the protein. Structure 22, 199-208.

  10. Bognar P, Nemeth I, Mayer B, Haluszka D, Wikonkal N, Ostorhazi E, John S, Paulsson M, Smyth N, Pasztoi M, Buzas EI, Szipocs R, Kolonics A, Temesvari E, and Karpati S (2014). Reduced inflammatory threshold indicates skin barrier defect in transglutaminase 3 knockout mice. J Invest Dermatol 134, 105-111.

  11. Bonar D, and Hanisch FG (2014). Trefoil factor family domains represent highly efficient conformational determinants for n-linked n,n'-di-n-acetyllactosediamine (lacdinac) synthesis. J Biol Chem 289, 29677-29690.

  12. Borck G, de Vries L, Wu HJ, Smirin-Yosef P, Nürnberg G, Lagovsky I, Ishida LH, Thierry P, Wieczorek D, Nürnberg P, Foley J, Kubisch C, and Basel-Vanagaite L (2014). Homozygous truncating ptprf mutation causes athelia. Hum Genet 133, 1041-7.

  13. Borgal L, Rinschen MM, Dafinger C, Hoff S, Reinert MJ, Lamkemeyer T, Lienkamp SS, Benzing T, and Schermer B (2014). Casein kinase 1 alpha phosphorylates the wnt regulator jade-1 and modulates its activity. J Biol Chem 289, 26344-26356.

  14. Breitenkamp AF, Matthes J, Nass RD, Sinzig J, Lehmkuhl G, Nürnberg P, and Herzig S (2014). Rare mutations of cacnb2 found in autism spectrum disease-affected families alter calcium channel function. PLoS One 9, e95579.

  15. Brinkmann K, and Kashkar H (2014). Targeting the mitochondrial apoptotic pathway: A preferred approach in hematologic malignancies? Cell Death Dis 5, e1098.

  16. Brinkmann K, Hombach A, Michael Seeger J, Wagner-Stippich D, Klubertz D, Krönke M, Abken H, and Kashkar H (2014). SMAC mimetic potentiates tumor susceptibility towards natural killer cell-mediated killing. Leuk Lymphoma 55, 456-465.

  17. Brown A, Augustin M, Junger M, Zutt M, Dissemond J, Rabe E, Kaufmann R, Simon M, Stucker M, Karrer S, Koenen W, Vanscheidt W, Scharfetter-Kochanek K, Wollina U, Krieg T, and Eming SA (2014). Randomized standard-of-care-controlled trial of a silica gel fibre matrix in the treatment of chronic venous leg ulcers. Eur J Dermatol 24, 210-216.

  18. Brunn A, Mihelcic M, Carstov M, Hummel L, Geier F, Schmidt A, Saupe L, Utermöhlen O, and Deckert M (2014a). Il-10, Il-4, and stat6 promote an m2 milieu required for termination of p0106-125-induced murine experimental autoimmune neuritis. Am J Pathol 184, 2627-2640.

  19. Brunn A, Utermöhlen O, Mihelcic M, Saupe L, Fiocco Z, Schmidt A, Carstov M, Montesinos-Rongen M, and Deckert M (2014). Costimulatory molecule cd40 is essential for myelin protein 0 peptide 106-125-induced experimental autoimmune neuritis in mice. J Neuropathol Exp Neurol 73, 454-466.

  20. Burgute BD, Peche VS, Steckelberg AL, Glockner G, Gassen B, Gehring NH, and Noegel AA (2014). Nkap is a novel rs-related protein that interacts with rna and rna binding proteins. Nucleic Acids Res 42, 3177-3193.

  21. Burtscher V, Schicker K, Novikova E, Pohn B, Stockner T, Kugler C, Singh A, Zeitz C, Lancelot ME, Audo I, Leroy BP, Freissmuth M, Herzig S, Matthes J, and Koschak A (2014). Spectrum of cav1.4 dysfunction in congenital stationary night blindness type 2. Biochim Biophys Acta 1838, 2053-2065.

  22. Carnevalli LS, Scognamiglio R, Cabezas-Wallscheid N, Rahmig S, Laurenti E, Masuda K, Jockel L, Kuck A, Sujer S, Polykratis A, Erlacher M, Pasparakis M, Essers MA, and Trumpp A (2014). Improved hsc reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B. J Exp Med 211, 769-779.

  23. Chatterjee S, Wieczorek C, Schottle J, Siobal M, Hinze Y, Franz T, Florin A, Adamczak J, Heukamp LC, Neumaier B, and Ullrich RT (2014). Transient antiangiogenic treatment improves delivery of cytotoxic compounds and therapeutic outcome in lung cancer. Cancer Res 74, 2816-2824.

  24. Coutelle O, Hornig-Do HT, Witt A, Andree M, Schiffmann LM, Piekarek M, Brinkmann K, Seeger JM, Liwschitz M, Miwa S, Hallek M, Krönke M, Trifunovic A, Eming SA, Wiesner RJ, Hacker UT, and Kashkar H (2014). Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing. EMBO Mol Med 6, 624-639.

  25. Dahlhoff M, Frances D, Kloepper JE, Paus R, Schafer M, Niemann C, and Schneider MR (2014). Overexpression of epigen during embryonic development induces reversible, egfr-dependent sebaceous gland hyperplasia. Mol Cell Biol 34, 3086-9.

  26. Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, Eftychi C, Lin J, Corona T, Hermance N, Zelic M, Kirsch P, Basic M, Bleich A, Kelliher M, and Pasparakis M (2014). Ripk1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature 513, 90-94.

  27. Dejanovic B, and Schwarz G (2014). Neuronal nitric oxide synthase-dependent S-nitrosylation of gephyrin regulates gephyrin clustering at gabaergic synapses. J Neurosci 34, 7763-7768.

  28. Dejanovic B, Lal D, Catarino CB, Arjune S, Belaidi AA, Trucks H, Vollmar C, Surges R, Kunz WS, Motameny S, Altmüller J, Kohler A, Neubauer BA, Epicure C, Nürnberg P, Noachtar S, Schwarz G, and Sander T (2014). Exonic microdeletions of the gephyrin gene impair gabaergic synaptic inhibition in patients with idiopathic generalized epilepsy. Neurobiol Dis 67, 88-96.

  29. Dejanovic B, Semtner M, Ebert S, Lamkemeyer T, Neuser F, Luscher B, Meier JC, and Schwarz G (2014). Palmitoylation of gephyrin controls receptor clustering and plasticity of gabaergic synapses. PLoS Biol 12, e1001908.

  30. Dibue M, Kamp MA, Neumaier F, Steiger HJ, Hanggi D, Hescheler J, and Schneider T (2014). Cardiac phenomena during kainic-acid induced epilepsy and lamotrigine antiepileptic therapy. Epilepsy Res 108, 666-674.

  31. Diermeier S, Kolovos P, Heizinger L, Schwartz U, Georgomanolis T, Zirkel A, Wedemann G, Grosveld F, Knoch TA, Merkl R, Cook PR, Langst G, and Papantonis A (2014). Tnf-alpha signalling primes chromatin for nf-kappa b binding and induces rapid and widespread nucleosome repositioning. Genome biology 15, 536.

  32. Dogan SA, Pujol C, Maiti P, Kukat A, Wang S, Hermans S, Senft K, Wibom R, Rugarli EI, and Trifunovic A (2014). Tissue-specific loss of dars2 activates stress responses independently of respiratory chain deficiency in the heart. Cell Metab 19, 458-469.

  33. Doss S, Lohmann K, Seibler P, Arns B, Klopstock T, Zuhlke C, Freimann K, Winkler S, Lohnau T, Drungowski M, Nürnberg P, Wiegers K, Lohmann E, Naz S, Kasten M, Bohner G, Ramirez A, Endres M, and Klein C (2014). Recessive dystonia-ataxia syndrome in a turkish family caused by a cox20 (fam36a) mutation. J Neurol 261, 207-212.

  34. Dreidax D, Bannert S, Henrich KO, Schroder C, Bender S, Oakes CC, Lindner S, Schulte JH, Duffy D, Schwarzl T, Saadati M, Ehemann V, Benner A, Pfister S, Fischer M, and Westermann F (2014). P19-ink4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in mycn-amplified neuroblastomas. Hum Mol Genet 23, 6826-376.

  35. Eckes B, Krieg T, and Wickstrom SA (2014). Role of integrin signaling through integrin-linked kinase (ilk) in skin physiology and pathology. Exp Dermatol 23, 453-6.

  36. Eckes B, Moinzadeh P, Sengle G, Hunzelmann N, and Krieg T (2014). Molecular and cellular basis of scleroderma. J Mol Med (Berl) 92, 913-924.

  37. Eguether T, Ermolaeva MA, Zhao Y, Bonnet MC, Jain A, Pasparakis M, Courtois G, and Tassin AM (2014). The deubiquitinating enzyme cyld controls apical docking of basal bodies in ciliated epithelial cells. Nat Commun 5, 4585.

  38. Ehlken H, Krishna-Subramanian S, Ochoa-Callejero L, Kondylis V, Nadi NE, Straub BK, Schirmacher P, Walczak H, Kollias G, and Pasparakis M (2014). Death receptor-independent fadd signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific nemo knockout. Cell Death Differ 21, 1721-32.

  39. Elsayed SM, Heller R, Thoenes M, Zaki MS, Swan D, Elsobky E, Zuhlke C, Ebermann I, Nürnberg G, Nürnberg P, and Bolz HJ (2014). Autosomal dominant sca5 and autosomal recessive infantile sca are allelic conditions resulting from sptbn2 mutations. Eur J Hum Genet 22, 286-288.

  40. Eming SA (2014). Evolution of immune pathways in regeneration and repair: Recent concepts and translational perspectives. Semin Immunol 26, 275-276.

  41. Escobar-Henriques M, and Langer T (2014). Dynamic survey of mitochondria by ubiquitin. EMBO Rep 15, 231-243.

  42. Fabian J, Lodrini M, Oehme I, Schier MC, Thole TM, Hielscher T, Kopp-Schneider A, Opitz L, Capper D, von Deimling A, Wiegand I, Milde T, Mahlknecht U, Westermann F, Popanda O, Roels F, Hero B, Berthold F, Fischer M, Kulozik AE, Witt O, and Deubzer HE (2014). Grhl1 acts as tumor suppressor in neuroblastoma and is negatively regulated by mycn and hdac3. Cancer Res 74, 2604-2616.

  43. Fernandez-Cuesta L, Peifer M, Lu X, Sun R, Ozretic L, Seidel D, Zander T, Leenders F, George J, Müller C, Dahmen I, Pinther B, Bosco G, Konrad K, Altmüller J, Nürnberg P, Achter V, Lang U, Schneider PM, Bogus M, Soltermann A, Brustugun OT, Helland A, Solberg S, Lund-Iversen M, Ansen S, Stoelben E, Wright GM, Russell P, Wainer Z, Solomon B, Field JK, Hyde R, Davies MP, Heukamp LC, Petersen I, Perner S, Lovly CM, Cappuzzo F, Travis WD, Wolf J, Vingron M, Brambilla E, Haas SA, Büttner R, and Thomas RK (2014). Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids. Nat Commun 5, 3518.

  44. Fernandez-Cuesta L, Plenker D, Osada H, Sun R, Menon R, Leenders F, Ortiz-Cuaran S, Peifer M, Bos M, Dassler J, Malchers F, Schottle J, Vogel W, Dahmen I, Koker M, Ullrich RT, Wright GM, Russell PA, Wainer Z, Solomon B, Brambilla E, Nagy-Mignotte H, Moro-Sibilot D, Brambilla CG, Lantuejoul S, Altmüller J, Becker C, Nürnberg P, Heuckmann JM, Stoelben E, Petersen I, Clement JH, Sanger J, Muscarella LA, la Torre A, Fazio VM, Lahortiga I, Perera T, Ogata S, Parade M, Brehmer D, Vingron M, Heukamp LC, Büttner R, Zander T, Wolf J, Perner S, Ansen S, Haas SA, Yatabe Y, and Thomas RK (2014). Cd74-nrg1 fusions in lung adenocarcinoma. Cancer Discov 4, 415-422.

  45. Fischer B, Metzger M, Richardson R, Knyphausen P, Ramezani T, Franzen R, Schmelzer E, Bloch W, Carney TJ, and Hammerschmidt M (2014). P53 and tap63 promote keratinocyte proliferation and differentiation in breeding tubercles of the zebrafish. PLoS Genet 10, e1004048.

  46. Florea F, Bernards C, Caproni M, Kleindienst J, Hashimoto T, Koch M, and Sitaru C (2014). Ex vivo pathogenicity of anti-laminin gamma1 autoantibodies. Am J Pathol 184, 494-506.

  47. Franko A, von Kleist-Retzow JC, Neschen S, Wu M, Schommers P, Bose M, Kunze A, Hartmann U, Sanchez-Lasheras C, Stoehr O, Huntgeburth M, Brodesser S, Irmler M, Beckers J, de Angelis MH, Paulsson M, Schubert M, and Wiesner RJ (2014). Liver adapts mitochondrial function to insulin resistant and diabetic states in mice. J Hepatol 60, 816-823.

  48. Frohlich M, Dejanovic B, Kashkar H, Schwarz G, and Nussberger S (2014). S-palmitoylation represents a novel mechanism regulating the mitochondrial targeting of bax and initiation of apoptosis. Cell Death Dis 5, e1057.

  49. Gao J, Schatton D, Martinelli P, Hansen H, Pla-Martin D, Barth E, Becker C, Altmueller J, Frommolt P, Sardiello M, and Rugarli EI (2014). Cluh regulates mitochondrial biogenesis by binding mrnas of nuclear-encoded mitochondrial proteins. J Cell Biol 207, 213-223.

  50. Gee HY, Otto EA, Hurd TW, Ashraf S, Chaki M, Cluckey A, Vega-Warner V, Saisawat P, Diaz KA, Fang H, Kohl S, Allen SJ, Airik R, Zhou W, Ramaswami G, Janssen S, Fu C, Innis JL, Weber S, Vester U, Davis EE, Katsanis N, Fathy HM, Jeck N, Klaus G, Nayir A, Rahim KA, Al Attrach I, Al Hassoun I, Ozturk S, Drozdz D, Helmchen U, O'Toole JF, Attanasio M, Lewis RA, Nürnberg G, Nürnberg P, Washburn J, MacDonald J, Innis JW, Levy S, and Hildebrandt F (2014). Whole-exome resequencing distinguishes cystic kidney diseases from phenocopies in renal ciliopathies. Kidney Int 85, 880-887.

  51. Geibel M, Badurek S, Horn JM, Vatanashevanopakorn C, Koudelka J, Wunderlich CM, Bronneke HS, Wunderlich FT, and Minichiello L (2014). Ablation of trkb signalling in cck neurons results in hypercortisolism and obesity. Nat Commun 5, 3427.

  52. Glockner G, Hulsmann N, Schleicher M, Noegel AA, Eichinger L, Gallinger C, Pawlowski J, Sierra R, Euteneuer U, Pillet L, Moustafa A, Platzer M, Groth M, Szafranski K, and Schliwa M (2014). The genome of the foraminiferan reticulomyxa filosa. Curr Biol 24, 11-18.

  53. Gravemann S, Brinkkötter PT, Vehreschild JJ, Franke B, Ehren K, Bunemann E, Orbach H, Wei V, Hellmich M, Benzing T, and Fatkenheuer G (2014). Low-grade proteinuria is highly prevalent in hiv-positive patients on antiretroviral treatment. AIDS. DOI: 10.1097/QAD.0000000000000324.

  54. Guay-Woodford LM, Bissler JJ, Braun MC, Bockenhauer D, Cadnapaphornchai MA, Dell KM, Kerecuk L, Liebau MC, Alonso-Peclet MH, Shneider B, Emre S, Heller T, Kamath BM, Murray KF, Moise K, Eichenwald EE, Evans J, Keller RL, Wilkins-Haug L, Bergmann C, Gunay-Aygun M, Hooper SR, Hardy KK, Hartung EA, Streisand R, Perrone R, and Moxey-Mims M (2014). Consensus expert recommendations for the diagnosis and management of autosomal recessive polycystic kidney disease: Report of an international conference. J Pediatr 165, 611-7.

  55. Hagmann H, Bossung V, Belaidi AA, Fridman A, Karumanchi SA, Thadhani R, Schermer B, Mallmann P, Schwarz G, Benzing T, and Brinkkötter PT (2014). Low-molecular weight heparin increases circulating sflt-1 levels and enhances urinary elimination. PLoS One 9, e85258.

  56. Hagmann H, Kuczkowski A, Ruehl M, Lamkemeyer T, Brodesser S, Horke S, Dryer S, Schermer B, Benzing T, and Brinkkötter PT (2014). Breaking the chain at the membrane: Paraoxonase 2 counteracts lipid peroxidation at the plasma membrane. FASEB J 28, 1769-1779.

  57. Hanisch FG, Bonar D, Schloerer N, and Schroten H (2014). Human trefoil factor 2 is a lectin that binds alpha-glcnac-capped mucin glycans with antibiotic activity against helicobacter pylori. J Biol Chem 289, 27363-27375.

  58. Hartwig S, Raschke S, Knebel B, Scheler M, Irmler M, Passlack W, Müller S, Hanisch FG, Franz T, Li X, Dicken HD, Eckardt K, Beckers J, de Angelis MH, Weigert C, Haring HU, Al-Hasani H, Ouwens DM, Eckel J, Kotzka J, and Lehr S (2014). Secretome profiling of primary human skeletal muscle cells. Biochim Biophys Acta 1844, 1011-1017.

  59. Havarushka N, Fischer-Schrader K, Lamkemeyer T, and Schwarz G (2014). Structural basis of thermal stability of the tungsten cofactor synthesis protein moab from pyrococcus furiosus. PLoS One 9, e86030.

  60. Herrmann G, Knudsen L, Madershahian N, Muhlfeld C, Frank K, Rahmanian P, Wahlers T, Wittwer T, and Ochs M (2014). Effects of exogenous surfactant on the non-heart-beating donor lung graft in experimental lung transplantation - a stereological study. J Anat 224, 594-602.

  61. Hess ME, and Brüning JC (2014). The fat mass and obesity-associated (fto) gene: Obesity and beyond? Biochim Biophys Acta 1842, 2039-4.

  62. Horner M, Kaufmann B, Cotugno G, Wiedtke E, Büning H, Grimm D, and Weber W (2014). A chemical switch for controlling viral infectivity. Chem Commun (Camb) 50, 10319-10322.

  63. Hosel M, Lucifora J, Michler T, Holz G, Gruffaz M, Stahnke S, Zoulim F, Durantel D, Heikenwalder M, Nierhoff D, Millet R, Salvetti A, Protzer U, and Büning H (2014). Hepatitis B virus infection enhances susceptibility toward adeno-associated viral vector transduction in vitro and in vivo. Hepatology 59, 2110-2120.

  64. Hoyer-Kuhn H, Semler O, Garbes L, Zimmermann K, Becker J, Wollnik B, Schoenau E, and Netzer C (2014). A nonclassical ifitm5 mutation located in the coding region causes severe osteogenesis imperfecta with prenatal onset. J Bone Miner Res 29, 1387-1391.

  65. Hussain MS, Battaglia A, Szczepanski S, Kaygusuz E, Toliat MR, Sakakibara S, Altmuller J, Thiele H, Nurnberg G, Moosa S, Yigit G, Beleggia F, Tinschert S, Clayton-Smith J, Vasudevan P, Urquhart JE, Donnai D, Fryer A, Percin F, Brancati F, Dobbie A, Smigiel R, Gillessen-Kaesbach G, Wollnik B, Noegel AA, Newman WG, and Nurnberg P (2014). Mutations in ckap2l, the human homolog of the mouse radmis gene, cause filippi syndrome. Am J Hum Gen 95, 622-632.

  66. Kelly BT, Graham SC, Liska N, Dannhauser PN, Höning S, Ungewickell EJ, and Owen DJ (2014). Clathrin adaptors. Ap2 controls clathrin polymerization with a membrane-activated switch. Science 345, 459-463.

  67. Keusekotten K, Bade VN, Meyer-Teschendorf K, Sriramachandran AM, Fischer-Schrader K, Krause A, Horst C, Schwarz G, Hofmann K, Dohmen RJ, and Praefcke GJ (2014). Multivalent interactions of the sumo-interaction motifs in ring finger protein 4 determine the specificity for chains of the sumo. Biochem J 457, 207-214.

  68. Khan MA, Rupp VM, Orpinell M, Hussain MS, Altmüller J, Steinmetz MO, Enzinger C, Thiele H, Hohne W, Nürnberg G, Baig SM, Ansar M, Nürnberg P, Vincent JB, Speicher MR, Gonczy P, and Windpassinger C (2014). A missense mutation in the pisa domain of hssas-6 causes autosomal recessive primary microcephaly in a large consanguineous pakistani family. Hum Mol Genet 23, 5940-9.

  69. Kim C, and Pasparakis M (2014a). Epidermal p65/nf-kappa b signalling is essential for skin carcinogenesis. EMBO Mol Med 6, 970-983.

  70. Kim C, and Pasparakis M (2014b). Rip kinase 3 in necroptosis: Does it take two or more to kill? Cell Death Differ 21, 1505-1507.

  71. Kobold S, Steffen J, Chaloupka M, Grassmann S, Henkel J, Castoldi R, Zeng Y, Chmielewski M, Schmollinger J, Schnurr M, Rothenfusser S, Schendel DJ, Abken H, Sustmann C, Niederfellner G, Klein C, Bourquin C, and Endres S (2014). Bispecific t cell recruiting antibody enhances anti-tumor activity of adoptive t cell transfer. Oncol Res Treat 37, 239-239.

  72. Kohli P, Bartram MP, Habbig S, Pahmeyer C, Lamkemeyer T, Benzing T, Schermer B, and Rinschen MM (2014). Label-free quantitative proteomic analysis of the yap/taz interactome. Am J Physiol Cell Physiol 306, C805-818.

  73. Komlosi K, Hadzsiev K, Garbes L, Martinez Carrera LA, Pal E, Sigurethsson JH, Magnusson O, Melegh B, and Wirth B (2014). Exome sequencing identifies laing distal myopathy myh7 mutation in a roma family previously diagnosed with distal neuronopathy. Neuromuscul Disord 24, 156-161.

  74. Kondadi AK, Wang S, Montagner S, Kladt N, Korwitz A, Martinelli P, Herholz D, Baker MJ, Schauss AC, Langer T, and Rugarli EI (2014). Loss of the M-AAA protease subunit afg(3)l(2) causes mitochondrial transport defects and tau hyperphosphorylation. EMBO J 33, 1011-1026.

  75. Kornfeld JW, and Brüning JC (2014). Regulation of metabolism by long, non-coding rnas. Front Genet 5, 57.

  76. Koziel R, Ruckenstuhl C, Albertini E, Neuhaus M, Netzberger C, Bust M, Madeo F, Wiesner RJ, and Jansen-Durr P (2014). Methionine restriction slows down senescence in human diploid fibroblasts. Aging cell 13, 1038-1048.

  77. Krug C, Wiesinger M, Abken H, Schuler-Thurner B, Schuler G, Dorrie J, and Schaft N (2014). A gmp-compliant protocol to expand and transfect cancer patient T cells with mrna encoding a tumor-specific chimeric antigen receptor. Cancer Immunol Immunother 63, 999-1008.

  78. Kukat A, Dogan SA, Edgar D, Mourier A, Jacoby C, Maiti P, Mauer J, Becker C, Senft K, Wibom R, Kudin AP, Hultenby K, Flogel U, Rosenkranz S, Ricquier D, Kunz WS, and Trifunovic A (2014). Loss of ucp2 attenuates mitochondrial dysfunction without altering ros production and uncoupling activity. PLoS Genet 10, e1004385.

  79. Kurschat CE, Muller RU, Franke M, Maintz D, Schermer B, and Benzing T (2014). An approach to cystic kidney diseases: The clinician's view. Nat Rev Nephrol 10, 687-699.

  80. Kye MJ, Niederst ED, Wertz MH, Goncalves ID, Akten B, Dover KZ, Peters M, Riessland M, Neveu P, Wirth B, Kosik KS, Sardi SP, Monani UR, Passini MA, and Sahin M (2014). SMN regulates axonal local translation via miR-183/mtor pathway. Hum Mol Genet 23, 6318-31.

  81. Lepperhof V, Polchynski O, Kruttwig K, Bruggemann C, Neef K, Drey F, Zheng Y, Ackermann JP, Choi YH, Wunderlich FT, Hoehn M, Hescheler J, and Saric T (2014). Bioluminescent imaging of genetically selected induced pluripotent stem cell-derived cardiomyocytes after transplantation into infarcted heart of syngeneic recipients. PLoS One 9, e107363.

  82. Lettmann S, Bloch W, Maass T, Niehoff A, Schulz JN, Eckes B, SA, Bonaldo P, Paulsson M, and Wagener R (2014). Col6a1 null mice as a model to study skin phenotypes in patients with collagen VI related myopathies: Expression of classical and novel collagen VI variants during wound healing. PLoS One 9, e105686.

  83. Li P, Meinke P, Huong le TT, Wehnert M, and Noegel AA (2014). Contribution of sun1 mutations to the pathomechanism in muscular dystrophies. Hum Mutat 35, 452-461.

  84. Liebau MC (2014). An emerging molecular understanding and novel targeted treatment approaches in pediatric kidney diseases. Front Pediatr 2, 68.

  85. Liggett JL, Choi CK, Donnell RL, Kihm KD, Kim JS, Min KW, Noegel AA, and Baek SJ (2014). Nonsteroidal anti-inflammatory drug sulindac sulfide suppresses structural protein nesprin-2 expression in colorectal cancer cells. Bba-Gen Subjects 1840, 322-331.

  86. Liu Y, Liu X, Hao W, Decker Y, Schomburg R, Fulop L, Pasparakis M, Menger MD, and Fassbender K (2014). IKKbeta deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology. J Neurosci 34, 12982-12999.

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